Publications - Page 2
| Authors | Citation | Abstract | Title | Delivery Method | Organism |
|---|
| Ding, X-Z, Iversen, P., Cluck, M.W., Knezetic, J.A. and Adrian, T.E. | Biochem Biophys Res Commun 1999 Jul 22;261(1):218-23 | Epidemiologic and animal studies have linked pancreatic cancer growth with fat intake, especially... | Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells | Scrape Delivery | cell culture: human pancreatic cancer cell lines |
| Dorsky RI, Sheldahl LC, Moon RT | Dev Biol. 2002 Jan 15;241(2):229-37 | The Wnt/beta-catenin signaling pathway plays multiple roles during embryonic development, only a ... | A transgenic Lef1/beta-catenin-dependent reporter is expressed in spatially restricted domains th... | Microinjection | zebrafish |
| Draper BW, Morcos PA, Kimmel CB | Genesis. 2001 Jul;30(3):154-6 | No abstract available. | Inhibition of zebrafish fgf8 pre-mRNA splicing with morpholino oligos: A quantifiable method for ... | Microinjection | zebrafish |
| Dressman J, Kincer J, Matveev SV, Guo L, Greenberg RN, Guerin T, Meade D, Li XA, Zhu W, Uittenbog... | J Clin Invest. 2003 Feb;111(3):389-97 | Protease inhibitors decrease the viral load in HIV patients, however the patients develop hypertr... | HIV protease inhibitors promote atherosclerotic lesion formation independent of dyslipidemia by i... | oligo bathing | cell culture: THP-1 cells |
| Dupre A, Jessus C, Ozon R, Haccard O | EMBO J. 2002 Aug 1;21(15):4026-36 | In Xenopus oocytes, the c-mos proto-oncogene product has been proposed to act downstream of proge... | Mos is not required for the initiation of meiotic maturation in Xenopus oocytes | Microinjection | Xenopus |
| Dutton K, Dutton JR, Pauliny A, Kelsh RN | Genesis. 2001 Jul;30(3):188-9 | No abstract available. | A morpholino phenocopy of the colourless mutant | Microinjection | zebrafish |
| Ekker SC | Yeast 2000 Dec;17(4):302-306 | The vertebrate genome contains a predicted 50 000-100 000 genes, many of unknown function. The re... | Morphants: a new systematic vertebrate functional genomics approach | not applicable | zebrafish |
| Ekker SC, Larson JD | Genesis. 2001 Jul;30(3):89-93 | No abstract available. | Morphant technology in model developmental systems | not applicable | not applicable |
| Erter CE, Wilm TP, Basler N, Wright CV, Solnica-Krezel L | Development. 2001 Sep;128(18):3571-83 | The dorsal ectoderm of the vertebrate gastrula was proposed by Nieuwkoop to be specified towards ... | Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo | Microinjection | zebrafish |
| Etheridge LA, Wu T, Liang JO, Ekker SC, Halpern ME | Genesis. 2001 Jul;30(3):164-9 | No abstract available. | Floor plate develops upon depletion of tiggy-winkle and sonic hedgehog | Microinjection | zebrafish |
| Feldman B, Concha ML, Saude L, Parsons MJ, Adams RJ, Wilson SW, Stemple DL | Curr Biol. 2002 Dec 23;12(24):2129-35 | Activities of a variety of signaling proteins that regulate embryogenesis are limited by endogeno... | Lefty antagonism of squint is essential for normal gastrulation | Microinjection | zebrafish |
| Feldman B, Stemple DL | Genesis. 2001 Jul;30(3):175-7 | No abstract available. | Morpholino phenocopies of sqt, oep, and ntl mutations | Microinjection | zebrafish |
| Fisher ME, Isaacs HV, Pownall ME | Development 2002 Mar;129(6):1307-15 | This paper addresses the molecular mechanisms that regulate the transcriptional activation of the... | eFGF is required for activation of XmyoD expression in the myogenic cell lineage of Xenopus laevi... | Microinjection | Xenopus |
| Frazzetto G, Klingbeil P, Bouwmeester T | Mech Dev. 2002 Apr;113(1):3-14 | Gastrulation in vertebrates is a highly dynamic process driven by convergent extension movements ... | Xenopus marginal coil (Xmc), a novel FGF inducible cytosolic coiled-coil protein regulating gast... | Microinjection | Xenopus laevis |
| Fuchikami T, Mitsunaga-Nakatsubo K, Amemiya S, Hosomi T, Watanabe T, Kurokawa D, Kataoka M, Harad... | Development. 2002 Nov 15;129(22):5205-5216 | Signals from micromere descendants play a crucial role in sea urchin development. In this study, ... | T-brain homologue (HpTb) is involved in the archenteron induction signals of micromere descendant... | Microinjection | Sea urchins |
| Furthauer M, Reifers F, Brand M, Thisse B, Thisse C | Development 2001 Jun;128(12):2175-86 | In looking for novel factors involved in the regulation of the fibroblast growth factor (FGF) sig... | sprouty4 acts in vivo as a feedback-induced antagonist of FGF signaling in zebrafish | Microinjection | zebrafish |
| Garrity DM, Childs S, Fishman MC | Development. 2002 Oct;129(19):4635-45 | Holt-Oram syndrome is one of the autosomal dominant human "heart-hand" disorders, with a combinat... | The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome | Microinjection | zebrafish |
| Ghosh C, Iversen P | Antisense Nucleic Acid Drug Dev 2000 Aug;10(4):263-274 | Antisense oligonucleotides inhibit gene expression by interfering with transcription, translation... | Intracellular Delivery Strategies for Antisense Phosphorodiamidate Morpholino Oligos | various | cell culture: HeLa cells |
| Ghosh, C., Stein, D., Weller, D and Iversen, P | In Antisense Technology Part A, General Methods, Methods of Delivery, and RNA Studies. Methods in... | No abstract available. | Methods for Evaluation of Antisense Mechanisms of Action | | |
| Giles RV, Spiller DG, Clark RE, Tidd DM | Antisense Nucleic Acid Drug Dev 1999 Apr;9(2):213-20 | A 28-mer morpholino oligonucleotide analog was designed to hybridize to 8 bases of intron 1 and e... | Antisense morpholino oligonucleotide analog induces missplicing of c-myc mRNA | streptolysin O | cell culture: human leukemia lines |
| Gregory M, Hanumanthaiah R, Jagadeeswaran P | Blood Cells Mol Dis. 2002 Nov-Dec;29(3):286-95 | ABSTRACTThe zebrafish is an excellent model for mammalian hemostasis and thrombosis since it poss... | Genetic analysis of hemostasis and thrombosis using vascular occlusion | Microinjection | zebrafish |
| Grosser T, Yusuff S, Cheskis E, Pack MA, FitzGerald GA | Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8418-23 | Study of the cyclooxygenases (COXs) has been limited by the role of COX-2 in murine reproduction ... | Developmental expression of functional cyclooxygenases in zebrafish | Microinjection | organ culture: mouse liver explants |
| Grune T, Reinheckel T, North JA, Li R, Bescos PB, Shringarpure R, Davies KJ | FASEB J. 2002 Oct;16(12):1602-10 | We find that ezrin, a cytoskeletal protein involved in anchoring actin to the cell membrane, is p... | Ezrin turnover and cell shape changes catalyzed by proteasome in oxidatively stressed cells | oligo bathing | cell culture: clone 9 liver epithelial cells |
| Habeck H, Odenthal J, Walderich B, Maischein H, Schulte-Merker S | Curr Biol. 2002 Aug 20;12(16):1405-12 | Blood vessels form either by the assembly and differentiation of mesodermal precursor cells (vasc... | Analysis of a zebrafish VEGF receptor mutant reveals specific disruption of angiogenesis | Microinjection | zebrafish |
| Hall CJ, Flores MV, Davidson AJ, Crosier KE, Crosier PS | Dev Biol. 2002 Nov 1;251(1):105-117 | The precise assembly of an integrated network of blood vessels is essential for the survival of v... | Radar Is Required for the Establishment of Vascular Integrity in the Zebrafish | Microinjection | zebrafish |
| Heasman J | Dev Biol. 2002 Mar 15;243(2):209-14 | Since morpholino oligos were first introduced as a means to inhibit gene function in embryos, in ... | Morpholino oligos: making sense of antisense? | Microinjection | Xenopus |
| Heasman J, Kofron M, and Wylie C | Developmental Biology 2000 222: 124-134 | Xenopus embryos develop dorsal/ventral and anterior/posterior axes as a result of the activity of... | Beta-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach | Microinjection | Xenopus |
| Heasman J, Wessely O, Langland R, Craig EJ, Kessler DS | Dev Biol. 2001 Dec 15;240(2):377-86 | VegT is an essential maternal regulator of germ layer specification in Xenopus. The localization ... | Vegetal Localization of Maternal mRNAs Is Disrupted by VegT Depletion | Microinjection | Xenopus |
| Heisenberg CP, Houart C, Take-Uchi M, Rauch GJ, Young N, Coutinho P, Masai I, Caneparo L, Concha ... | Genes Dev. 2001 Jun 1;15(11):1427-34 | Zebrafish embryos homozygous for the masterblind (mbl) mutation exhibit a striking phenotype in w... | A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformati... | Microinjection | zebrafish |
| Henry CA, Urban MK, Dill KK, Merlie JP, Page MF, Kimmel CB, Amacher SL | Development. 2002 Aug 1;129(15):3693-3704 | The formation of somites, reiterated structures that will give rise to vertebrae and muscles, is ... | Two linked hairy/Enhancer of split-related zebrafish genes, her1 and her7, function together to r... | Microinjection | zebrafish |
| Hermanto U, Zong CS, Li W, Wang LH | Mol Cell Biol. 2002 Apr;22(7):2345-65 | The insulin-like growth factor I (IGF-I) receptor (IGF-IR) is known to regulate a variety of cell... | RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-depe... | Scrape Delivery | cell culture: Swiss 3T3 cells |
| Hjorth JT, Connor RM, Key B | Int J Dev Biol. 2002;46(4):583-96 | hlx1 is a related homeobox gene expressed in a dynamic spatiotemporal expression pattern during d... | Role of hlx1 in zebrafish brain morphogenesis | Microinjection | zebrafish |
| Holley SA, Julich D, Rauch GJ, Geisler R, Nusslein-Volhard C | Development. 2002 Mar;129(5):1175-83 | Somite formation is thought to be regulated by an unknown oscillator mechanism that causes the ce... | her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somi... | Microinjection | zebrafish |
| Horsfield J, Ramachandran A, Reuter K, LaVallie E, Collins-Racie L, Crosier K, Crosier P | Mech Dev. 2002 Jul;115(1-2):15-26 | We have isolated a zebrafish cadherin that is orthologous to human LI-cadherin (CDH17). Zebrafish... | Cadherin-17 is required to maintain pronephric duct integrity during zebrafish development | Microinjection | zebrafish |
| Houart C, Caneparo L, Heisenberg CP, Barth KA, Take-Uchi M, Wilson SW | Neuron 2002 35:255–265 | Cells at the anterior boundary of the neural plate (ANB) can induce telencephalic gene expression... | Establishment of the Telencephalon during Gastrulation by Local Antagonism of Wnt Signaling | Microinjection | zebrafish |
| Howard EW, Newman LA, Oleksyn DW, Angerer RC, Angerer LM | Development 2001 128(3):365-375 | Localization of nuclear beta-catenin initiates specification of vegetal fates in sea urchin embry... | SpKrl: a direct target of (beta)-catenin regulation required for endoderm differentiation in sea ... | Microinjection | Sea urchins |
| Howell M, Inman GJ, Hill CS | Development. 2002 Jun 15;129(12):2823-2834 | In early Xenopus embryos, the prototypical XFast-1/Smad2/Smad4 complex ARF1 is induced at the Mix... | A novel Xenopus Smad-interacting forkhead transcription factor (XFast-3) cooperates with XFast-1 ... | Microinjection | Xenopus |
| Hoshijima K, Metherall JE, Grunwald DJ | Genes Dev. 2002 Oct 1;16(19):2518-29 | Although the vertebrate embryonic midline plays a critical role in determining the left/right asy... | A protein disulfide isomerase expressed in the embryonic midline is required for left/right asymm... | Microinjection | zebrafish |
| Hsieh DJ, Liao CF | Br J Pharmacol. 2002 Nov 6;137(6):782-792 | 1. A zebrafish M(2) muscarinic acetylcholine receptor (mAChR) gene was cloned. It encodes 495 ami... | Zebrafish M(2) muscarinic acetylcholine receptor: cloning, pharmacological characterization, expr... | Microinjection | zebrafish |
| Huang H, Liu N, Lin S | Genesis. 2001 Jul;30(3):134-6 | No abstract available. | Pdx-1 knockdown reduces insulin promoter activity in zebrafish | Microinjection | zebrafish |
| Hudziak RM, Summerton J, Weller DD, Iversen PL | Antisense Nucleic Acid Drug Dev 2000 Jun;10(3):163-76 | The phosphorodiamidate Morpholino oligomers (PMO) are a new class of antisense agents that inhibi... | Antiproliferative effects of steric blocking phosphorodiamidate morpholino antisense agents direc... | Scrape Delivery | cell culture: various cell lines |
| Hudziak RM, Barofsky E, Barofsky DF, Weller DL, Huang SB, Weller DD | Antisense Nucleic Acid Drug Dev 1996 Winter;6(4):267-72 | Oligomers possessing the Morpholino phosphorodiamidate backbone were evaluated for resistance to ... | Resistance of morpholino phosphorodiamidate oligomers to enzymatic degradation | | not applicable |
| Hunter MP, Prince VE | Dev Biol. 2002 Jul 15;247(2):367-389 | The pharyngeal arches are one of the defining features of the vertebrates, with the first arch fo... | Zebrafish Hox Paralogue Group 2 Genes Function Redundantly as Selector Genes to Pattern the Seco... | Microinjection | zebrafish |
| Imai KS, Satou Y, Satoh N | Development. 2002 Jun;129(11):2723-32 | Multiple functions of a Zic-like zinc finger transcription factor gene (Cs-ZicL) were identified ... | Multiple functions of a Zic-like gene in the differentiation of notochord, central nervous system... | Microinjection | Ciona savignyi |
| Imai KS, Satoh N, Satou Y | Development. 2002 Apr 1;129(7):1729-38 | In early Ciona savignyi embryos, nuclear localization of beta-catenin is the first step of endode... | Early embryonic expression of FGF4/6/9 gene and its role in the induction of mesenchyme and notoc... | Microinjection | Ciona savignyi |
| Imai Y, Gates MA, Melby AE, Kimelman D, Schier AF, Talbot WS | Development 2001 Jun;128(12):2407-20 | Ventralizing transcriptional repressors in the Vox/Vent family have been proposed to be important... | The homeobox genes vox and vent are redundant repressors of dorsal fates in zebrafish | Microinjection | zebrafish |
| Imai Y, Talbot WS | Genesis. 2001 Jul;30(3):160-3 | No abstract available. | Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations | Microinjection | zebrafish |
| Itoh M, Noutomi T, Chiba H, Mizuguchi J | Oral Oncol. 2002 Dec;38(8):752-6 | Carboplatin (CBDCA) has been widely used for the treatment of oral squamous cell carcinoma (SCC).... | BcI-xL antisense treatment sensitizes Bcl-xL-overexpressing squamous cell carcinoma cells to carb... | Scrape Delivery | cell culture: squamous cell carcinoma |
| Iversen PL | Curr Opin Mol Ther 2001 Jun;3(3):235-8 | The phosphorodiamidate morpholino oligomers (PMOs) are a distinct class of oligonucleotide analog... | Phosphorodiamidate morpholino oligomers: favorable properties for sequence-specific gene inactiva... | | |
| Jost JP, Oakeley EJ, Zhu B, Benjamin D, Thiry S, Siegmann M, Jost YC | Nucleic Acis Res 2001 Nov 1 29(21):4452-4461 | Changes in gene expression during mouse myoblast differentiation were monitored by DNA microarray... | 5-Methycytosine DNA glycosylase participates in the genome-wide loss of DNA methylation occurring... | Special Delivery | cell culture: mouse G8 myoblasts |
