Publications - Page 4
| Authors | Citation | Abstract | Title | Delivery Method | Organism |
|---|
| Miller CT, Kimmel CB | Genesis. 2001 Jul;30(3):186-7 | No abstract available | Morpholino phenocopies of endothelin 1 (sucker) and other anterior arch class mutations | Microinjection | zebrafish |
| Monga SP, Monga HK, Tan X, Mule K, Pediaditakis P, Michalopoulos GK | Gastroenterology. 2003 Jan;124(1):202-216 | BACKGROUND & AIMS: Wnt/beta-catenin pathway activation occurs during liver growth in hepatoblasto... | beta-catenin antisense studies in embryonic liver cultures: Role in proliferation, apoptosis, and... | oligo bathing | organ culture: mouse liver explants |
| Moore JC, Sumerel JL, Schnackenberg BJ, Nichols JA, Wikramanayake A, Wessel GM, Marzluff WF | Mol Cell Biol. 2002 Jul 1;22(13):4863-4875 | cdk4 mRNA and protein are constitutively expressed in sea urchin eggs and throughout embryonic de... | Cyclin D and cdk4 Are Required for Normal Development beyond the Blastula Stage in Sea Urchin Emb... | Microinjection | Sea urchins |
| Morcos PA | Methods Enzymol 2000;313:174-89 | No abstract available. | Gene switching: analyzing a broad range of mutations using steric block antisense oligonucleotide... | Scrape Delivery | Cell Culture: human HeLa pLuc 705 cell and HeLa pRLCMV |
| Morcos PA | Genesis. 2001 Jul;30(3):94-102 | One of the many features that make morpholino oligos unique among the antisense structural types ... | Achieving efficient delivery of morpholino oligos in cultured cells | Special Delivery | cell culture: HeLa AntisenseTest System |
| Muller F, Lakatos L, Dantonel J, Strahle U, Tora L | Curr Biol 2001 Feb 20;11(4):282-287 | General transcription factors TFIIA, B, D, E, F, H, and RNA polymerase II (Pol II) are required f... | TBP is not universally required for zygotic RNA polymerase II transcription in zebrafish | Microinjection | zebrafish |
| Munshi C, Graeff R, Lee HC | J Biol Chem 2002 Dec 20;277(51):49453-8 | Granulocytic differentiation of human HL-60 cells can be induced by retinoic acid and is accompan... | Evidence for a causal role of CD38 expression in granulocytic differentiation of human HL-60 cell... | Special Delivery | cell culture: HL60 cells |
| Muraoka O | Nippon Yakurigaku Zasshi. 2002 Aug;120(2):96-100. Japanese. | The technology for the control of gene function is necessary not only to study development, but a... | [The new technology for controlling gene function in zebrafish] | not applicable | not applicable |
| Nasevicius A, Ekker SC | Curr Opin Mol Ther. 2001 Jun;3(3):224-8 | Unconventional antisense technology has entered the mainstream for both therapeutic and functiona... | The zebrafish as a novel system for functional genomics and therapeutic development applications | | zebrafish |
| Nasevicius A, Larson J, Ekker SC | Yeast 2000 Dec;17(4):294-301 | Angiogenesis is a fundamental vertebrate developmental process that requires signalling by the se... | Distinct requirements for zebrafish angiogenesis revealed by a VEGF-A morphant | Microinjection | zebrafish |
| Nasevicius A and Ekker SC | Nature Genetics 2000 October; 26(2): 216 - 220 | The sequencing of the zebrafish genome should be completed by the end of 2002. Direct assignment ... | Effective targeted gene 'knockdown' in zebrafish | Microinjection | zebrafish |
| Nielsen PE | Annu Rev Biophys Biomol Struct. 1995 24:167-83. Review | This review discusses the recent developments of DNA analogues with nonphosphodiester backbones i... | DNA analogues with nonphosphodiester backbones | | |
| Nishi E, Prat A, Hospital V, Elenius K, Klagsbrun M. | EMBO J 2001 Jul 2;20(13):3342-3350 | Heparin-binding epidermal growth factor-like growth factor (HB-EGF), a mitogen and chemotactic fa... | N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor ... | Special Delivery | cell culture: HaCaT keratinocytes |
| Nlend MC, Bookman RJ, Conner GE, Salathe M. | Am J Respir Cell Mol Biol 2002 Oct;27(4):436-45 | In ciliated airway epithelial cells, purinergic stimulation increases both intracellular calcium ... | Regulator of g-protein signaling protein 2 modulates purinergic calcium and ciliary beat frequenc... | Special Delivery | cell culture:human endothelial cells (ECs), ovine epithelial cells |
| Nutt SL, Bronchain OJ, Hartley KO, Amaya E | Genesis. 2001 Jul;30(3):110-3 | Morpholino (MO) based inhibition of translational initiation represents an attractive methodology... | Comparison of morpholino based translational inhibition during the development of Xenopus laevis ... | Microinjection | X.laevis & X.tropicalis |
| Ohnuma S, Mann F, Boy S, Perron M, Harris WA | Methods. 2002 Dec;28(4):411-9 | The analysis of gene function during retinal development can be addressed by perturbing gene expr... | Lipofection strategy for the study of Xenopus retinal development. | lipid-based | Xenopus |
| Paganelli AR, Ocana OH, Prat MI, Franco PG, Lopez SL, Morelli L, Adamo AM, Riccomagno MM, Matsuba... | Mech Dev 2001 Sep;107(1-2):119-31 | We analyzed the influence of presenilins on the genetic cascades that control neuronal differenti... | The Alzheimer-related gene presenilin-1 facilitates sonic hedgehog expression in Xenopus primary ... | Microinjection | Xenopus laevis |
| Pak JH, Manevich Y, Kim HS, Feinstein SI, Fisher AB | J Biol Chem. 2002 Dec 20;277(51):49927-34. Epub 2002 Oct 07 | 1-cys peroxiredoxin (1-cysPrx), a member of the peroxiredoxin superfamily, reduces phospholipid h... | An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lu... | Special Delivery | cell culture: L2 cells |
| Park EK, Warner N, Mood K, Pawson T, Daar IO | Mol Cell Biol. 2002 May;22(10):3404-14 | Low-molecular-weight protein tyrosine phosphatase (LMW-PTP) has been implicated in the regulation... | Low-molecular-weight protein tyrosine phosphatase is a positive component of the fibroblast growt... | Microinjection | Xenopus |
| Parsons MJ, Campos I, Hirst EM, Stemple DL | Development 2002 Jul;129(14):3505-12 | Muscular dystrophy is frequently caused by disruption of the dystrophin-glycoprotein complex (DGC... | Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos. | Microinjection | zebrafish |
| Partridge M, Vincent A, Matthews P, Puma J, Stein D, Summerton J | Antisense Nucleic Acid Drug Dev. 1996 Fall;6(3):169-75 | We report a simple and effective means for delivering Morpholino antisense oligos into the cytoso... | A simple method for delivering morpholino antisense oligos into the cytoplasm of cells | Scrape Delivery | cell culture: Hela and rat FT02B liver cells |
| Patton EE, Zon LI | Nat Rev Genet. 2001 Dec;2(12):956-66. | Inventive genetic screens in zebrafish are revealing new genetic pathways that control vertebrate... | The Art and Design of Genetic Screens: Zebrafish | Microinjection | zebrafish |
| Penberthy WT, Shafizadeh E, Lin S | Front Biosci. 2002 Jun 1;7:D1439-53 | Much of our current understanding of the function of genes modulating the normal process of embry... | The zebrafish as a model for human disease | | zebrafish |
| Phillips BT, Bolding K, Riley BB | Dev Biol 2001 Jul 15;235(2):351-365 | Members of the fibroblast growth factor (FGF) family of peptide ligands have been implicated in o... | Zebrafish fgf3 and fgf8 Encode Redundant Functions Required for Otic Placode Induction | Microinjection | zebrafish |
| Picker A, Scholpp S, Bohli H, Takeda H, Brand M. | Development. 2002 Jul 1;129(13):3227-3239 | The pax2.1 gene encodes a paired-box transcription factor that is one of the earliest genes to be... | A novel positive transcriptional feedback loop in midbrain-hindbrain boundary development is reve... | Microinjection | zebrafish |
| Polli M, Amaya E | Development. 2002 Jun;129(12):2917-27 | Xenopus laevis has been a particularly useful model organism for identifying factors involved in ... | A study of mesoderm patterning through the analysis of the regulation of Xmyf-5 expression. | Microinjection | Xenopus tropicalis |
| Poulain M, Lepage T | Development. 2002 Nov 1;129(21):4901-4914 | Endoderm specification in zebrafish is mediated by the zygotic transcription factors Bon/Mixer, F... | Mezzo, a paired-like homeobox protein is an immediate target of Nodal signalling and regulates en... | Microinjection | zebrafish |
| Prasadan K, Daume E, Preuett B, Spilde T, Bhatia A, Kobayashi H, Hembree M, Manna P, Gittes GK | Diabetes. 2002 Nov;51(11):3229-36 | The embryonic pancreas is thought to develop from pluripotent endodermal cells that give rise to ... | Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas | oligo bathing | Mouse embryonic tissue |
| Prescott SM, Yost HJ | Proc. Natl. Acad. Sci. USA. 2002 July 9; 99 (14): 9084-9086 | No abstract available. | The COXes of Danio: From mechanistic model to experimental therapeutics | Microinjection | zebrafish |
| Qin G, Taylor M, Ning YY, Iversen P, Kobzik L | Antisense Nucleic Acid Drug Dev 2000 Feb;10(1):11-6 | Morpholino antisense oligomers directed against the cytokine tumor necrosis factor (TNF-alpha) ca... | In vivo evaluation of a morpholino antisense oligomer directed against tumor necrosis factor-alp... | in vivo: intranasal | BALB/c mice |
| Raible F, Brand M | Mech Dev 2001 Sep;107(1-2):105-17 | Several molecules of the Fibroblast growth factor family have been implicated in the development ... | Tight transcriptional control of the ETS domain factors Erm and Pea3 by Fgf signaling during earl... | Microinjection | zebrafish |
| Rex M, Hilton E, Old R | Int J Dev Biol. 2002 Mar;46(2):217-26 | We have investigated the induction of the six Xenopus nodal-related genes, Xnr1-Xnr6, by maternal... | Multiple interactions between maternally-activated signalling pathways control Xenopus nodal-rela... | Microinjection | Xenopus laevis |
| Richard-Parpaillon L, Heligon C, Chesnel F, Boujard D, Philpott A | Dev Biol. 2002 Apr 15;244(2):407-17 | The insulin-like growth factors (IGFs) are well known mitogens, both in vivo and in vitro, while ... | The IGF Pathway Regulates Head Formation by Inhibiting Wnt Signaling in Xenopus | Microinjection | Xenopus |
| Ricker JL, Mata JE, Iversen PL, Gattone VH | Kidney Int. 2002 Jan;61 Suppl 1:125-131 | c-myc antisense oligonucleotide treatment ameliorates murine ARPKD.BACKGROUND: Overexpression of ... | c-myc antisense oligonucleotide treatment ameliorates murine ARPKD | in vivo: injection | C57BL/6J-cpk/+ Mice |
| Ring C, Ogata S, Meek L, Song J, Ohta T, Miyazono K, Cho KW | Genes Dev. 2002 Apr 1;16(7):820-35 | We investigated the regulation of the activin/nodal-inducible distal element (DE) of the Xenopus ... | The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcriptio... | Microinjection | Xenopus tropicalis |
| Ross JJ, Shimmi O, Vilmos P, Petryk A, Kim H, Gaudenz K, Hermanson S, Ekker SC, O'Connor MB, Mars... | Nature 2001 Mar 22;410(6827):479-483 | Bone morphogenetic protein (BMP) signalling regulates embryonic dorsal-ventral cell fate decision... | Twisted gastrulation is a conserved extracellular BMP antagonist | Microinjection | zebrafish |
| Rozema DB, Ekena K, Lewis DL, Loomis AG, Wolff JA | Bioconjug Chem. 2003 Jan-Feb;14(1):51 | Endosomolysis, a critical barrier to efficient delivery of macromolecules such as nucleic acids, ... | Endosomolysis by Masking of a Membrane-Active Agent (EMMA) for Cytoplasmic Release of Macromolecu... | peptide-based | cell culture: HeLa AntisenseTest System |
| Sakaguchi T, Kuroiwa A, Takeda H | Mech Dev 2001 Sep;107(1-2):25-38 | Vertebrate endoderm development has recently become the focus of intense investigation. We have i... | A novel sox gene, 226D7, acts downstream of Nodal signaling to specify endoderm precursors in zeb... | Microinjection | zebrafish |
| Satou Y, Imai KS, Satoh N | Genesis. 2001 Jul;30(3):103-6 | First, using morpholino against lacZ, we demonstrate that the morpholino specifically suppresses ... | Action of morpholinos in Ciona embryos | Microinjection | Ciona savignyi |
| Satou Y, Yagi K, Imai KS, Yamada L, Nishida H, Satoh N | Dev Genes Evol. 2002 Mar;212(2):87-92 | In ascidians, maternal factor(s) localized in the myoplasm of the egg are essential for specifica... | macho-1-related genes in Ciona embryos | Microinjection | Ciona savignyi |
| Satou Y, Imai KS, Satoh N | Development. 2001 Sep;128(18):3559-70 | In early Ciona embryos, nuclear accumulation of beta-catenin is most probably the first step of e... | Early embryonic expression of a LIM-homeobox gene Cs-lhx3 is downstream of beta-catenin and respo... | Microinjection | Ciona savignyi |
| Satow R, Chan TC, Asashima M | Biochem Biophys Res Commun 2002 Jul 5;295(1):85-91 | In a screen for genes expressed in neural tissues and pronephroi, we isolated a novel gene, named... | Molecular cloning and characterization of dullard: a novel gene required for neural development | Microinjection | Xenopus |
| Saulnier DM, Ghanbari H, Brandli AW | Dev Biol. 2002 Aug 1;248(1):13-28 | In the vertebrate embryo, development of the excretory system is characterized by the successive ... | Essential function of wnt-4 for tubulogenesis in the Xenopus pronephric kidney | Microinjection | Xenopus |
| Sazani P, Gemignani F, Kang SH, Maier MA, Manoharan M, Persmark M, Bortner D, Kole R | Nat Biotechnol. 2002 Dec;20(12):1228-33 | Systemically injected 2'-O-methoxyethyl (2'-O-MOE)-phosphorothioate and PNA-4K oligomers (peptide... | Systemically delivered antisense oligomers upregulate gene expression in mouse tissues | in vivo: injection | Mice: EGFP transgenic |
| Sazani P, Kang SH, Maier MA, Wei C, Dillman J, Summerton J, Manoharan M, Kole R | Nucleic Acids Res. 2001 Oct 1;29(19):3965-74 | The antisense activity of oligomers with 2'-O-methyl (2'-O-Me) phosphorothioate, 2'-O-methoxyethy... | Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs | scrape loading and free uptake | cell culture: HeLa cells |
| Schmajuk G, Sierakowska H, Kole R | J Biol Chem 1999 Jul 30;274(31):21783-9 | A novel, positive read-out assay that quantifies only sequence-specific nuclear activity of antis... | Antisense oligonucleotides with different backbones. Modification of splicing pathways and effic... | scrape loading and free uptake | cell culture: Hela and K562 cells |
| Scholpp S, Brand M | Genesis. 2001 Jul;30(3):129-33 | No abstract available. | Morpholino-induced knockdown of zebrafish engrailed genes eng2 and eng3 reveals redundant and uni... | Microinjection | zebrafish |
| Schwarz-Romond T, Asbrand C, Bakkers J, Kuhl M, Schaeffer HJ, Huelsken J, Behrens J, Hammerschmid... | Genes Dev. 2002 Aug 15;16(16):2073-84 | Wnt signals control decisive steps in development and can induce the formation of tumors. Canonic... | The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradati... | Microinjection | zebrafish |
| Schweickert A, Deissler K, Blum M, Steinbeisser H | Genesis. 2001 Jul;30(3):144-8 | The mucus secreting cement gland is the anterior-most ectodermal organ of the Xenopus embryo. The... | Pitx1 and Pitx2c are required for ectopic cement gland formation in xenopus laevis | Microinjection | Xenopus |
| Segawa H, Miyashita T, Hirate Y, Higashijima S, Chino N, Uyemura K, Kikuchi Y, Okamoto H. | Neuron 2001 May;30(2):423-36 | Islet-2 is a LIM/homeodomain-type transcription factor of the Islet-1 family expressed in embryon... | Functional repression of islet-2 by disruption of complex with ldb impairs peripheral axonal outg... | Microinjection | zebrafish |
