Publications - Page 5
| Authors | Citation | Abstract | Title | Delivery Method | Organism |
|---|
| Sehnert AJ, Huq A, Weinstein BM, Walker C, Fishman M, Stainier DYR. | Nat Genet 2002 May;31(1):106-10 | Mutations of the gene (TNNT2) encoding the thin-filament contractile protein cardiac troponin T a... | Cardiac troponin T is essential in sarcomere assembly and cardiac contractility | Microinjection | zebrafish |
| Shepherd IT, Beattie CE, Raible DW | Dev Biol 2001 Mar 15;231(2):420-435 | We have identified zebrafish orthologues of glial cell line-derived neurotrophic factor (GDNF) an... | Functional Analysis of Zebrafish GDNF | Microinjection | zebrafish |
| Shimizu T, Yamanaka Y, Nojima H, Yabe T, Hibi M, Hirano T | Mech Dev. 2002 Oct;118(1-2):125 | Dharma/Bozozok (Dha/Boz) is a homeodomain protein containing an Engrailed homology (Eh) 1 repress... | A novel repressor-type homeobox gene, ved, is involved in dharma/bozozok-mediated dorsal organiz... | Microinjection | zebrafish |
| Shinya M, Koshida S, Sawada A, Kuroiwa A, Takeda H | Development 2001 Nov 1;128(21):4153-4164 | The telencephalon is formed in the most anterior part of the central nervous system (CNS) and is ... | Fgf signalling through MAPK cascade is required for development of the subpallial telencephalon i... | Microinjection | zebrafish |
| Shumay E, Song X, Wang HY, Malbon CC | Mol Biol Cell. 2002 Nov;13(11):3943-54 | Insulin stimulates a rapid phosphorylation and sequestration of the beta(2)-adrenergic receptor. ... | pp60Src Mediates Insulin-stimulated Sequestration of the beta(2)-Adrenergic Receptor: Insulin St... | Special Delivery | cell culture: Human epidermoid carcinoma A431 |
| Siddall LS, Barcroft LC, Watson AJ | Mol Reprod Dev. 2002 Dec;63(4):413-421 | Morpholino antisense oligonucleotides act by blocking translation of their target gene products a... | Targeting gene expression in the preimplantation mouse embryo using morpholino antisense oligonuc... | Special Delivery and lipid-based | preimplantation mouse embryos |
| Smith AW, Matson DO, Stein DA, Skilling DE, Kroeker AD, Berke T, Iversen PL | Curr Opin Mol Ther. 2002 Apr;4(2):177-84 | The Earth's oceans are the primary reservoir for an emerging family of RNA viruses, the Calicivi... | Antisense treatment of caliciviridae: an emerging disease agent of animals and humans | | |
| Solomon KS, Fritz A | Development. 2002 Jul;129(13):3127-36 | Sensory placodes are ectodermal thickenings that give rise to elements of the vertebrate cranial ... | Concerted action of two dlx paralogs in sensory placode formation | Microinjection | zebrafish |
| Song MH, Huang FZ, Chang GY, Weisblat DA | Development. 2002 Aug;129(15):3681-92 | We have identified homologs of the Drosophila pair-rule gene even-skipped in the glossiphoniid le... | Expression and function of an even-skipped homolog in the leech Helobdella robusta | Microinjection | Helobdella (leech) |
| Souopgui J, Solter M, Pieler T | EMBO J. 2002 Dec 1;21(23):6429-6439 | We have isolated the Xenopus p21-activated kinase 3 (XPak3) by virtue of its expression in the te... | XPak3 promotes cell cycle withdrawal during primary neurogenesis in Xenopus laevis | Microinjection | Xenopus |
| Spokony RF, Aoki Y, Saint-Germain N, Magner-Fink E, Saint-Jeannet JP | Development. 2002 Jan;129(2):421-32 | The SOX family of transcription factors has been implicated in cell fate specification during emb... | The transcription factor Sox9 is required for cranial neural crest development in Xenopus | Microinjection | Xenopus laevis |
| Squillace R, Chenault D, Wang E | Dev Biol. 2002 Oct 1;250(1):218 | Growth factor withdrawal from proliferating myoblasts induces the expression of muscle-specific g... | Inhibition of Muscle Differentiation by the Novel Muscleblind-Related Protein CHCR | Scrape Delivery | cell culture: C2C12 cells |
| Stalmans I, Lambrechts D, De Smet F, Jansen S, Wang J, Maity S, Kneer P, Von Der Ohe M, Swillen A... | Nat Med. 2003 Feb;9(2):173-82 | Hemizygous deletion of chromosome 22q11 (del22q11) causes thymic, parathyroid, craniofacial an... | VEGF: A modifier of the del22q11 (DiGeorge) syndrome? | Microinjection | zebrafish |
| Stein D, Foster E, Huang SB, Weller D, Summerton J | Antisense Nucleic Acid Drug Dev. 1997 Jun;7(3):151-7 | Cell-free translation studies were carried out to compare the efficacy and specificity of four an... | A specificity comparison of four antisense types: morpholino, 2'-O-methyl RNA, DNA, and phosphoro... | in vitro: TNT | |
| Stein DA, Skilling DE, Iversen PL, Smith AW | Antisense Nucleic Acid Drug Dev. 2001 Oct;11(5):317-25 | Caliciviruses infect and cause disease in animals and humans. They are nonenveloped, positive-str... | Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomer... | Scrape Delivery | cell culture: PK-15 and Vero cells |
| Sugiyama S, Nakamura H | Development. 2003 Feb 1;130(3):451-462 | Mature chick optic tecta consist of 16 laminae and receive retinal fiber projections in a precise... | The role of Grg4 in tectal laminar formation | Electroporation | chick embryo |
| Sumanas S, Kim HJ, Hermanson S, Ekker SC | Genesis. 2001 Jul;30(3):114-8. | No abstract available. | Zebrafish frizzled-2 morphant displays defects in body axis elongation | Microinjection | zebrafish |
| Sumanas S, Ekker SC | Genesis. 2001 Jul;30(3):119-22 | No abstract available.Oligos designed to two different orthologues of Xfz7 gene | Xenopus frizzled-7 morphant displays defects in dorsoventral patterning and convergent extension ... | Microinjection | Xenopus laevis |
| Sumanas S, Larson JD | Briefings in Functional Genomics and Proteomics. 2002. 1(3):239-256 | Morpholino phosphorodiamidate anti-sense oligonucleotides (MPOs) have recently emerged as a tool ... | Morpholino phosphorodiamidate oligonucleotides in zebrafish: A recipe for functional genomics? | Microinjection | zebrafish |
| Summerton J | Biochimica et Biophysica Acta 1999 1489: 141-158 | RNase H-competent phosphorothioates (S-DNAs) have dominated the antisense field in large part bec... | Morpholino Antisense Oligomers: The Case for an RNase-H Independent Structural Type | | |
| Summerton J and Dwight Weller | Antisense & Nucleic Acid Drug Development 1997 7:187-195 | Antisense promised major advances in treating a broad range of intractable diseases, but in recen... | Morpholino Antisense Oligomers: Design, Preparation and Properties. | | |
| Summerton J, David Stein, Sung Ben Huang, Paula Matthews, Dwight Weller, and Michael Partridge | Antisense & Nucleic Acid Drug Development 1997 7: 63-70 | Morpholino and phosphorothioate (S-DNA) antisense oligos were compared in both cell-free and in-c... | Morpholino and Phosphorothioate Antisense Oligomers Compared in Cell-Free and In-Cell Systems | in vitro: TNT and scrape loading | cell culture: HeLa cells |
| Summerton J (submitted 1973, published 1979) | J Theor Biol 1979 May 7;78(1):61-75 | A general approach is proposed for development of anti-viral complexes capable of specific intrac... | Intracellular inactivation of specific nucleotide sequences: a general approach to the treatment ... | | |
| Suwanmanee T, Sierakowska H, Fucharoen S, Kole R | Mol Ther. 2002 Dec;6(6):718-26. | A HeLa cell line stably expressing the human beta-globin gene carrying thalassemic mutations beta... | Repair of a Splicing Defect in Erythroid Cells from Patients with beta-Thalassemia/HbE Disorder | scrape loading and syringe loading | cell culture: C2C12 cells |
| Suwanmanee T, Sierakowska H, Lacerra G, Svasti S, Kirby S, Walsh CE, Fucharoen S, Kole R | Mol Pharmacol. 2002 Sep;62(3):545-53. | Correct human beta-globin mRNA has been restored in erythroid cells from transgenic mice carrying... | Restoration of Human beta-Globin Gene Expression in Murine and Human IVS2-654 Thalassemic Erythro... | syringe loading and free uptake | cell culture: Hela and human erythroid precursor cells |
| Sweet HC, Gehring M, Ettensohn CA. | Development. 2002 Apr;129(8):1945-55 | Signals from micromere descendants play a critical role in patterning the early sea urchin embryo... | LvDelta is a mesoderm-inducing signal in the sea urchin embryo and can endow blastomeres with org... | Microinjection | sea urchin |
| Swertfeger DK, Bu G, Hui DY | J Biol Chem 2002 Feb 8;277(6):4141-6 | This research was undertaken to identify the cell surface receptor responsible for mediating apol... | Low density lipoprotein receptor-related protein mediates apolipoprotein E inhibition of smooth m... | Special Delivery | cell culture: mouse aortic smooth muscle |
| Szeto DP, Griffin KJ, Kimelman D | Development. 2002 Nov 1;129(21):5093-5101 | The recently identified zebrafish T-box gene hrT is expressed in the developing heart and in the ... | hrT is required for cardiovascular development in zebrafish | Microinjection | zebrafish |
| Tackett AJ, Wei L, Cameron CE, Raney KD | Nucleic Acids Res 2001 Jan 15;29(2):565-572 | Hepatitis C virus (HCV) helicase, non-structural protein 3 (NS3), is proposed to aid in HCV genom... | Unwinding of nucleic acids by HCV NS3 helicase is sensitive to the structure of the duplex | | |
| Tan C, Deardorff MA, Saint-Jeannet JP, Yang J, Arzoumanian A, Klein PS | Development. 2001 Oct 1;128(19):3665-3674. | Wnts are a family of secreted glycoproteins that are important for multiple steps in early develo... | Kermit, a frizzled interacting protein, regulates frizzled 3 signaling in neural crest developmen... | Microinjection | Xenopus |
| Taylor MF, Paulauskis JD, Weller DD, Kobzik L. | Cytokine. 1997 Sep;9(9):672-81. | The authors investigated the use of antisense oligomers specific for TNF-alpha (AS-2) and nonsens... | Comparison of efficacy of antisense oligomers directed toward TNF-alpha in helper T and macrophag... | Lipofectin | Cell Culture: RAW 264.7 and HT1 cells: a murine T helper cell |
| Taylor MF, Paulauskis JD, Weller DD, Kobzik L | J Biol Chem. 1996 Jul 19;271(29):17445-52 | Chemical modification of antisense oligonucleotides to increase nuclease resistance may improve t... | In vitro efficacy of morpholino-modified antisense oligomers directed against tumor necrosis fact... | culture: Incubation & free uptake | cell culture: RAW 264.7 cells |
| Taylor MF, Weller DD, Kobzik L | Antisense Nucleic Acid Drug Dev 1998 Jun;8(3):199-205 | Antisense oligomers can inhibit expression of a single gene in a sequence-specific manner. As a r... | Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macroph... | lipid-based | cell culture: mouse primary alveolar macrophages |
| Tidd DM, Giles RV, Broughton CM, Clark RE | BMC Mol Biol. 2001;2(1):13. | BACKGROUND: A study was undertaken to resolve preliminary conflicting results on the proliferatio... | Expression of c-myc is not critical for cell proliferation in established human leukemia lines | streptolysin O or electroporation | cell culture: human leukemia lines |
| Tiso N, Filippi A, Pauls S, Bortolussi M, Argenton F | Mech Dev. 2002 Oct;118(1-2):29. | In vertebrates, the embryonic dorsoventral asymmetry is regulated by the bone morphogenetic prote... | BMP signalling regulates anteroposterior endoderm patterning in zebrafish | Microinjection | zebrafish |
| Topczewska JM, Topczewski J, Shostak A, Kume T, Solnica-Krezel L, Hogan BL. | Genes Dev. 2001 Sep 15;15(18):2483-93 | Previous studies identified zebrafish foxc1a and foxc1b as homologs of the mouse forkhead gene, F... | The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish | Microinjection | zebrafish |
| Tsang M, Friesel R, Kudoh T, Dawid IB | Nat Cell Biol 2002 Feb;4(2):165-9 | Fibroblast growth factors (FGFs) are members of a family of some 30 secreted proteins important i... | Identification of Sef, a novel modulator of FGF signalling | Microinjection | zebrafish |
| Tucker RP | Dev Dyn 2001 Sep;222(1):115-9 | A key feature of vertebrate development is the formation of the neural crest. In the trunk, ne... | Abnormal neural crest cell migration after the in vivo knockdown of tenascin-C expression with mo... | Electroporation | chick embryo |
| Van Der Sar AM, Zivkovic D, Den Hertog J | Dev Dyn. 2002 Feb;223(2):292-297 | Receptor protein-tyrosine phosphatase alpha (RPTP alpha) is highly expressed in the developing re... | Eye defects in receptor protein-tyrosine phosphatase [alpha] knock-down zebrafish | Microinjection | zebrafish |
| Varga ZM, Amores A, Lewis KE, Yan YL, Postlethwait JH, Eisen JS, Westerfield M | Development. 2001 Sep;128(18):3497-509 | Sonic hedgehog (Shh) signaling patterns many vertebrate tissues. shh mutations dramatically affec... | Zebrafish smoothened functions in ventral neural tube specification and axon tract formation | Microinjection | zebrafish |
| Vendrell V, Gimnopoulos D, Becker T and Schimmang T | Int. J. Dev. Biol. 2001 45 (S1): S105-S106 | FGF3 has been involved in the development of the inner ear in a number of species including mous... | Functional analysis of FGF3 during zebrafish inner ear development. | Microinjection | zebrafish |
| Visser JA, Olaso R, Verhoef-Post M, Kramer P, Themmen APN, Ingraham HA. | Molecular Endocrinology 2001 15 (6): 936-945 | Mullerian inhibiting substance (MIS or anti-Mullerian hormone) is a member of the transforming gr... | The Serine/Threonine Transmembrane Receptor ALK2 Mediates Müllerian Inhibiting Substance Signalin... | Special Delivery | cell culture: RAW 264.7 cells |
| Wada S, Saiga H | Development. 2002 Dec 15;129(24):5597-5608 | Two axial structures, a neural tube and a notochord, are key structures in the chordate body plan... | HrzicN, a new Zic family gene of ascidians, plays essential roles in the neural tube and notochor... | Microinjection | Halocynthia roretzi (ascidian) |
| Wada S, Toyoda R, Yamamoto H, Saiga H | Dev Dyn 2002 Sep;225(1):46-53 | The brain (sensory vesicle) of the ascidian larvae is thought to be homologous to the vertebrate ... | Ascidian otx gene Hroth activates transcription of the brain-specific gene HrTRP | Microinjection | Halocynthia roretzi (ascidian) |
| Wages JM Jr; Wages GM; Matthews P; Weller D; Summerton J | Biotechniques. 1997 Dec;23(6):1116-21 | Nucleic acid isolation for amplification-based diagnostics requires techniques that do not co-pur... | Affinity purification of RNA: sequence-specific capture by nonionic morpholino probes | | |
| Wallace KN, Yusuff S, Sonntag JM, Chin AJ, Pack M | Genesis. 2001 Jul;30(3):141-3 | No abstract available. | Zebrafish hhex regulates liver development and digestive organ chirality | Microinjection | zebrafish |
| Walsh EC, Stainier DY | Science. 2001 293: 1670-2 | Cardiac valve formation is a complex process that involves cell signaling events between the myoc... | UDP–Glucose Dehydrogenase Required for Cardiac Valve Formation in Zebrafish | | zebrafish |
| Walshe J, Maroon H, McGonnell IM, Dickson C, Mason I. | Current Biology 2002 12(13): 1117–1123 | The hindbrain (brainstem) of all vertebrates follows a segmental developmental strategy and has b... | Establishment of Hindbrain Segmental Identity Requires Signaling by FGF3 and FGF8 | Microinjection | zebrafish |
| Wang G, Huang H, Dai R, Lee KY, Lin S, Mivechi NF | Genesis. 2001 Jul;30(3):195-7 | No abstract available. | Suppression of heat shock transcription factor HSF1 in zebrafish causes heat-induced apoptosis | Microinjection | zebrafish |
| Wei X, Malicki J | Nat Genet. 2002 Jun;31(2):150-7 | A layered organization of cells is a common architectural feature of many neuronal formations. Mu... | nagie oko, encoding a MAGUK-family protein, is essential for cellular patterning of the retina | Microinjection | zebrafish |
