Publications - Page 7
| Authors | Citation | Abstract | Title | Delivery Method | Organism |
|---|
| Her GM, Chiang CC, Chen WY, Wu JL | FEBS Lett 2003 Mar 13;538(1-3):125-33 | Mammalian liver fatty acid binding protein (L-FABP) is a small cytosolic protein in various tissu... | In vivo studies of liver-type fatty acid binding protein (L-FABP) gene expression in liver of tra... | Microinjection | zebrafish |
| Teraoka H, Dong W, Tsujimoto Y, Iwasa H, Endoh D, Ueno N, Stegeman JJ, Peterson RE, Hiraga T | Biochem Biophys Res Commun 2003 May 2;304(2):223-8 | The mechanism of toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is thought to result from... | Induction of cytochrome P450 1A is required for circulation failure and edema by 2,3,7,8-tetrachl... | Microinjection | zebrafish |
| Voronina E, Marzluff WF, Wessel GM | Dev Biol 2003 Apr 15;256(2):258-75 | Sea urchins are members of a limited group of animals in which meiotic maturation of oocytes is c... | Cyclin B synthesis is required for sea urchin oocyte maturation. | Microinjection | Sea urchins |
| Barreto G, Borgmeyer U, Dreyer C | Mech Dev 2003 Apr;120(4):415-28 | The germ cell nuclear factor (GCNF, NR6A1) is a nuclear orphan receptor that functions as a trans... | The germ cell nuclear factor is required for retinoic acid signaling during Xenopus development. | Microinjection | Xenopus |
| Chen F, Kook H, Milewski R, Gitler AD, Lu MM, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke ... | Cell 2002 Sep 20;110(6):713-23 | Hop is a small, divergent homeodomain protein that lacks certain conserved residues required for ... | Hop is an unusual homeobox gene that modulates cardiac development. | Microinjection | zebrafish |
| Barreto G, Reintsch W, Kaufmann C, Dreyer C. | Dev Biol 2003 May 15;257(2):329-42 | The germ cell nuclear factor (GCNF, NR6A1) is a nuclear orphan receptor first described in the mo... | The function of Xenopus germ cell nuclear factor (xGCNF) in morphogenetic movements during neurul... | Microinjection | Xenopus |
| Zhang J, Bai S, Tanase C, Nagase H, Sarras MP Jr. | Dev Genes Evol 2003 May 8; [epub ahead of print] | MMP activities are controlled by a combination of proteolytic pro-enzyme activation steps and inh... | The expression of tissue inhibitor of metalloproteinase 2 (TIMP-2) is required for normal develop... | Microinjection | zebrafish |
| Houston DW, Wylie C. | Development 2003 Jun;130(12):2695-704 | One of the earliest lineage restriction events in embryogenesis is the specification of the prima... | The Xenopus LIM-homeodomain protein Xlim5 regulates the differential adhesion properties of early... | Microinjection | Xenopus |
| Liu G, Liu C, Zhang S, He J, Liu N, Gupta S, Rusckowski M, Hnatowich DJ. | Nucl Med Commun 2003 Jun;24(6):697-705 | SUMMARYThis laboratory is exploring the use of morpholinos (MORFs), synthetic DNA analogues, for ... | Investigations of 99mTc morpholino pretargeting in mice. | In vivo: injection | Swiss NIH nude mice |
| Boguslavsky D, Ierusalimsky V, Malyshev A, Balaban P, Belyavsky A. | Neuroscience 2003 Jun 18;119(1):15-18 | In the present study, the applicability of antisense morpholino oligos for loss-of-function exper... | Selective blockade of gene expression in a single identified snail neuron. | Microinjection | Helix lucorum (snail) |
| Xiao T, Shoji W, Zhou W, Su F, Kuwada JY. | J Neurosci 2003 May 15;23(10):4190-8 | Class 4 semaphorins are a large class of transmembrane proteins that contain a sema domain and th... | Transmembrane Sema4E Guides Branchiomotor Axons to Their Targets in Zebrafish. | Microinjection | zebrafish |
| Xanthos JB, Kofron M, Tao Q, Schaible K, Wylie C, Heasman J. | Development 2002 Sep;129(17):4027-43 | Since the three main pathways (the Wnt, VegT and BMP pathways) involved in organizer and axis for... | The roles of three signaling pathways in the formation and function of the Spemann Organizer. | Microinjection | Xenopus |
| LeSueur JA, Fortuno ES 3rd, McKay RM, Graff JM. | Dev Cell 2002 Jun;2(6):771-83 | Before the nervous system establishes its complex array of cell types and connections, multipoten... | Smad10 is required for formation of the frog nervous system. | Microinjection | Xenopus |
| Zhu Y, Rice CD, Pang Y, Pace M, Thomas P | Proc Natl Acad Sci U S A 2003 Mar 4;100(5):2231-6 | The structures of membrane receptors mediating rapid, nongenomic actions of steroids have not bee... | Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an ... | Microinjection | zebrafish |
| Ettensohn CA, Illies MR, Oliveri P, De Jong DL. | Development 2003 Jul;130(13):2917-28 | In the sea urchin embryo, the large micromeres and their progeny function as a critical signaling... | Alx1, a member of the Cart1/Alx3/Alx4 subfamily of Paired-class homeodomain proteins, is an essen... | Microinjection | Sea urchins |
| Jiang K, Pereira E, Maxfield M, Russell B, Goudelock DM, Sanchez Y. | J Biol Chem. 2003 Jul 4;278(27):25207-17. Epub 2003 Apr 03. | Checkpoints are biochemical pathways that provide the cell with mechanisms to detect DNA damage a... | Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on... | Special Delivery | cell culture: HeLa cells |
| Joukov V, Chen J, Fox EA, Green JB, Livingston DM. | Proc Natl Acad Sci U S A 2001 Oct 9;98(21):12078-83 | The breast and ovarian susceptibility protein 1 (BRCA1) heterodimerizes with its structural relat... | Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis d... | Microinjection | Xenopus |
| Blanc V, Navaratnam N, Henderson JO, Anant S, Kennedy S, Jarmuz A, Scott J, Davidson NO. | J Biol Chem 2001 Mar 30;276(13):10272-83 | C to U editing of apolipoprotein B (apoB) mRNA involves the interaction of a multicomponent editi... | Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apo... | Special Delivery | cell culture: McArdle rat hepatoma |
| Spagnoli A, Torello M, Nagalla SR, Horton WA, Pattee P, Hwa V, Chiarelli F, Roberts CT Jr, Rosenf... | J Biol Chem 2002 May 24;277(21):18860-7 | The chondrogenesis process requires the ordered proliferation and differentiation of chondrocytes... | Identification of STAT-1 as a molecular target of IGFBP-3 in the process of chondrogenesis. | Special Delivery | cell culture: RCJ3.1C5.18 cells |
| Maton G, Thibier C, Castro A, Lorca T, Prigent C, Jessus C. | J Biol Chem. 2003 Jun 13;278(24):21439-49. Epub 2003 Apr 01. | Xenopus oocytes are arrested in meiotic prophase I and resume meiotic divisions in response to pr... | Cdc2-Cyclin B triggers H3 kinase activation of aurora-A in xenopus oocytes. | Microinjection | Xenopus |
| Lemjabbar H, Li D, Gallup M, Sidhu S, Drori E, Basbaum C. | J Biol Chem 2003 Apr 23; [epub ahead of print] | Cells dividing at the time of carcinogen exposure are at particular risk for neoplasia. Tobacco s... | Tobacco smoke-induced lung cell proliferation mediated by tumor necrosis factor alpha converting ... | Special Delivery | cell culture: NCIH292 cells |
| Moulton HM, Moulton JD | Curr Opin Mol Ther. 2003 Apr;5(2):123-32 | Cationic transport peptides conjugated to steric blocking antisense oligomers (oligos) increase o... | Peptide-assisted delivery of steric-blocking antisense oligomers | not applicable | not applicable |
| Moulton HM, Hase MC, Smith KM, Iversen PL | Antisense Nucleic Acid Drug Dev. 2003 Feb;13(1):31-43. | Phosphorodiamidate morpholino oligomers (PMO) are uncharged antisense molecules that bind complem... | HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers | peptide-coupled | cell culture: various Hela |
| Kwon HJ, Chung HM | Biochem Biophys Res Commun. 2003 Jul 11;306(4):1008-13 | Polycomb group (PcG) genes are required for the stable repression of the homeotic genes and other... | Yin Yang 1, a vertebrate Polycomb group gene, regulates antero-posterior neural patterning | Microinjection | Xenopus |
| Ng JK, Kawakami Y, Buscher D, Raya A, Itoh T, Koth CM, Rodriguez Esteban C, Rodriguez-Leon J, Gar... | Development. 2002 Nov;129(22):5161-70 | A major gap in our knowledge of development is how the growth and identity of tissues and organs ... | The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10 | Microinjection | zebrafish |
| Carruthers S, Mason J, Papalopulu N | Mech Dev. 2003 May;120(5):607-16 | The Xenopus p27(Xic1) gene encodes a cyclin dependent kinase (CDK) inhibitor of the Cip/Kip famil... | Depletion of the cell-cycle inhibitor p27(Xic1) impairs neuronal differentiation and increases th... | Microinjection | Xenopus tropicalis |
| Bink RJ, Habuchi H, Lele Z, Dolk E, Joore J, Rauch GJ, Geisler R, Wilson SW, Den Hertog J, Kimata... | J Biol Chem. 2003 Aug 15;278(33):31118-27. Epub 2003 Jun 01. | Heparan sulfate proteoglycans function in development and disease. They consist of a core protein... | Heparan sulfate 6-O-sulfotransferase is essential for muscle development in Zebrafish | Microinjection | zebrafish |
| Bellmeyer A, Krase J, Lindgren J, LaBonne C | Dev Cell. 2003 Jun;4(6):827-39 | The neural crest, a population of multipotent progenitor cells, is a defining feature of vertebra... | The Protooncogene c-Myc Is an Essential Regulator of Neural Crest Formation in Xenopus | Microinjection | Xenopus |
| Dutton KA, Pauliny A, Lopes SS, Elworthy S, Carney TJ, Rauch J, Geisler R, Haffter P, Kelsh RN | Development. 2001 Nov;128(21):4113-25 | Waardenburg-Shah syndrome combines the reduced enteric nervous system characteristic of Hirschspr... | Zebrafish colourless encodes sox10 and specifies non-ectomesenchymal neural crest fates | Microinjection | zebrafish |
| Sidi S, Friedrich RW, Nicolson T | Science. 2003 Jul 4;301(5629):96-9. Epub 2003 Jun 12. | The senses of hearing and balance in vertebrates rely upon the sensory hair cells (HCs) of the in... | NompC TRP Channel Required for Vertebrate Sensory Hair Cell Mechanotransduction | Microinjection | zebrafish |
| Stenkamp DL, Frey RA | Dev Biol. 2003 Jun 15;258(2):349-63 | Hedgehog (Hh) signaling is required for eye development in vertebrates; known roles in the zebraf... | Extraretinal and retinal hedgehog signaling sequentially regulate retinal differentiation in zebr... | Microinjection | zebrafish |
| O'Hara MF, Nibbio BJ, Craig RC, Nemeth KR, Charlap JH, Knudsen TB | Reprod Toxicol. 2003 Jul-Aug;17(4):365-75 | The peripheral benzodiazepine receptor (Bzrp) has been implicated in the control of several proce... | Mitochondrial benzodiazepine receptors regulate oxygen homeostasis in the early mouse embryo | | Mouse embryo |
| Zhang S, Ren J, Khan MF, Cheng AM, Abendschein D, Muslin AJ | Arterioscler Thromb Vasc Biol. 2003 Jul 3 [Epub ahead of print] | OBJECTIVE: Neointima formation occurs in arteries in response to mechanical or chemical injury an... | Grb2 Is Required for the Development of Neointima in Response to Vascular Injury | Scrape Delivery | cell culture: rat aortic smooth muscle cells |
| Zhang J, Bai S, Zhang X, Nagase H, Sarras MP Jr. | Matrix Biol. 2003 May;22(3):279-93 | Matrix metalloproteinases (MMPs) play important roles in the turnover of components of extracellu... | The expression of novel membrane-type matrix metalloproteinase isoforms is required for normal de... | Microinjection | zebrafish |
| Lee SA, Shen EL, Fiser A, Sali A, Guo S | Development. 2003 Jun;130(12):2669-79 | Vertebrate epibranchial placodes give rise to visceral sensory neurons that transmit vital inform... | The zebrafish forkhead transcription factor Foxi1 specifies epibranchial placode-derived sensory ... | Microinjection | zebrafish |
| Pandur P, Lasche M, Eisenberg LM, Kuhl M | Nature. 2002 Aug 8;418(6898):636-41 | Formation of the vertebrate heart requires a complex interplay of several temporally regulated si... | Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis | Microinjection | Xenopus |
| Latinkic BV, Mercurio S, Bennett B, Hirst EM, Xu Q, Lau LF, Mohun TJ, Smith JC | Development. 2003 Jun;130(11):2429-41 | Cyr61 is a secreted, heparin-binding, extracellular matrix-associated protein whose activities in... | Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling | Microinjection | Xenopus laevis |
| Lele Z, Folchert A, Concha M, Rauch GJ, Geisler R, Rosa F, Wilson SW, Hammerschmidt M, Bally-Cuif... | Development. 2002 Jul;129(14):3281-94 | N-cadherin (Ncad) is a classical cadherin that is implicated in several aspects of vertebrate emb... | parachute/n-cadherin is required for morphogenesis and maintained integrity of the zebrafish neur... | Microinjection | zebrafish |
| Xu X, Meiler SE, Zhong TP, Mohideen M, Crossley DA, Burggren WW, Fishman MC | Nat Genet. 2002 Feb;30(2):205-9 | The zebrafish embryo is transparent and can tolerate absence of blood flow because its oxygen is ... | Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin | Microinjection | zebrafish |
| Becker CG, Schweitzer J, Feldner J, Becker T, Schachner M | J Neurosci. 2003 Jul 16;23(15):6232-7 | To investigate the role of tenascin-R in nervous system development, we studied axon pathfinding ... | Tenascin-R as a repellent guidance molecule for developing optic axons in zebrafish | Microinjection | zebrafish |
| Wolff C, Roy S, Ingham PW | Curr Biol. 2003 Jul 15;13(14):1169-81 | BACKGROUND: In the zebrafish embryo, the differentiation of distinct muscle fiber types has been ... | Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the... | Microinjection | zebrafish |
| Iversen PL, Arora V, Acker AJ, Mason DH, Devi GR | Clin Cancer Res. 2003 Jul;9(7):2510-9 | PURPOSE: The overexpression of c-myc associated with uncontrolled cell proliferation is a frequen... | Efficacy of antisense morpholino oligomer targeted to c-myc in prostate cancer xenograft murine m... | Special Delivery | Cell Culture: PC-3 human androgen-independent prostate carcinoma |
| Gebski BL, Mann CJ, Fletcher S, Wilton SD | Hum Mol Genet. 2003 Aug 1;12(15):1801-11 | The mdx mouse model of muscular dystrophy arose due to a nonsense mutation in exon 23 of the dyst... | Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle. | In vivo: injection and cell culture | cell culture: mouse MDX muscle cells |
| Carreira-Barbosa F, Concha ML, Takeuchi M, Ueno N, Wilson SW, Tada M | Development. 2003 Sep 1;130(17):4037-404 | During vertebrate gastrulation, mesodermal and ectodermal cells undergo convergent extension, a p... | Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish. | Microinjection | zebrafish |
| Mayer AN, Fishman MC | Development. 2003 Sep 1;130(17):3917-3928 | Digestive organ development occurs through a sequence of morphologically distinct stages, from ov... | nil per os encodes a conserved RNA recognition motif protein required for morphogenesis and cytod... | Microinjection | zebrafish |
| Ly H, Nierlich DP, Olsen JC, Kaplan AH | J Virol. 2000 Nov;74(21):9937-45 | Several determinants that appear to promote the dimerization of murine retroviral genomic RNA hav... | Functional characterization of the dimer linkage structure RNA of Moloney murine sarcoma virus | Scrape Delivery | Molony murine sarcoma virus |
| Im HJ, Smirnov D, Yuhi T, Raghavan S, Olsson JE, Muscat GE, Koopman P, Loh H | Mol Pharmacol. 2001 Jun;59(6):1486-96 | Previously, we reported the presence of dual promoters, referred to as distal (DP) and proximal, ... | Transcriptional modulation of mouse mu-opioid receptor distal promoter activity by Sox18 | lipid-based | cell culture: neuronal NMB and non-neuronal HeLa cells |
| Schenk PW, Boersma AW, Brandsma JA, den Dulk H, Burger H, Stoter G, Brouwer J, Nooter K. | Cancer Res. 2001 Oct 1;61(19):6982-6 | The therapeutic potential of cisplatin, one of the most active and widely used anticancer drugs, ... | SKY1 is involved in cisplatin-induced cell kill in Saccharomyces cerevisiae, and inactivation of ... | Special Delivery | cell culture: human ovarian carcinoma A2780 cell line |
| Inada K, Horie T, Kusakabe T, Tsuda M. | Neurosci Lett. 2003 Aug 28;347(3):167-70 | The sequencing of the ascidian Ciona intestinalis genome was completed at the end of 2002. Effect... | Targeted knockdown of an opsin gene inhibits the swimming behaviour photoresponse of ascidian lar... | Microinjection | Ciona intestinalis |
| David NB, Sapede D, Saint-Etienne L, Thisse C, Thisse B, Dambly-Chaudiere C, Rosa FM, Ghysen A. | Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16297-302. Epub 2002 Nov 20 | Cell migration plays an essential role in many morphogenetic processes, and its deregulation has ... | Molecular basis of cell migration in the fish lateral line: role of the chemokine receptor CXCR4 ... | Microinjection | zebrafish |
