Publications - Page 62
| Authors | Citation | Abstract | Title | Delivery Method | Organism |
|---|
| Popplewell LJ, Adkin C, Arechavala-Gomeza V, Aartsma-Rus A, de Winter CL, Wilton SD, Morgan JE, M... | Neuromuscul Disord. 2010 Jan 13. [Epub ahead of print] | Duchenne muscular dystrophy (DMD) is caused by the lack of functional dystrophin protein, most co... | Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD ge... | Electroporation (Amaxa) | mouse expressing human dystrophin, cultured DMD cells |
| Schütte A, Hedrich J, Stöcker W, Becker-Pauly C | PLoS One. 2010 Jan 21;5(1):e8835 | BACKGROUND: Meprin metalloproteases are thought to be involved in basic physiological functions s... | Let It Flow: Morpholino Knockdown in Zebrafish Embryos Reveals a Pro-Angiogenic Effect of the Met... | | zebrafish |
| Christie TL, Carter A, Rollins EL, Childs SJ | Dev Biol. 2010 Jan 20. [Epub ahead of print] | Spleen tyrosine kinase (Syk) plays critical roles in B-cell and T-cell development, the maintenan... | Syk and Zap-70 function redundantly to promote angioblast migration | | zebrafish |
| Mitchell IC, Brown TS, Terada LS, Amatruda JF, Nwariaku FE | PLoS One. 2010 Jan 20;5(1):e8807 | BACKGROUND: Vascular endothelial cadherin (VE-cad) is essential for endothelial barrier integrity... | Effect of Vascular Cadherin Knockdown on Zebrafish Vasculature during Development | Microinjection | zebrafish |
| Sakamoto K, Onimaru K, Munakata K, Suda N, Tamura M, Ochi H, Tanaka M | PLoS One. 2009;4(4):e5121. Epub 2009 Apr 13 | We explored the molecular mechanisms of morphological transformations of vertebrate paired fin/li... | Heterochronic shift in Hox-mediated activation of sonic hedgehog leads to morphological changes d... | Microinjection | zebrafish |
| Kuo MW, Wang SH, Chang JC, Chang CH, Huang LJ, Lin HH, Yu AL, Li WH, Yu J | PLoS One. 2009;4(3):e4980. Epub 2009 Mar 25 | Although the human genome project has been completed for some time, the issue of the number of tr... | A novel puf-A gene predicted from evolutionary analysis is involved in the development of eyes an... | Microinjection | zebrafish |
| Matluk N, Rochiera JA, Karaczyn A, Adams TL, Verdi JM | BMC Biol. 2010 Jan 25;8(1):7. [Epub ahead of print] | ABSTRACT: BACKGROUND: Previous studies have linked neurotrophin receptor-interacting MAGE protein... | A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway | Endo-Porter | cell culture: HEK293 |
| Teoh PH, Shu-Chien AC, Chan WK | Dev Dyn. 2010 Jan 27. [Epub ahead of print] | pbx1, a TALE (three-amino acid loop extension) homeodomain transcription factor, is involved in a... | Pbx1 is essential for growth of zebrafish swim bladder | | zebrafish |
| Sazani P, Weller DL, Shrewsbury SB | Int J Toxicol. 2010 Jan 28. [Epub ahead of print] | Duchenne muscular dystrophy (DMD) is caused by dystrophin gene mutations. Restoration of dystroph... | Safety Pharmacology and Genotoxicity Evaluation of AVI-4658 | | Mouse, cynomolgus monkey |
| Komoike Y, Shimojima K, Liang JS, Fujii H, Maegaki Y, Osawa M, Fujii S, Higashinakagawa T, Yamamo... | J Hum Genet. 2010 Jan 29. [Epub ahead of print] | Array-based comparative genomic hybridization identified a 2.3-Mb microdeletion of 17p13.2p13.1 i... | A functional analysis of GABARAP on 17p13.1 by knockdown zebrafish | | zebrafish |
| Zhang J, Piontek J, Wolburg H, Piehl C, Liss M, Otten C, Christ A, Willnow TE, Blasig IE, Abdelil... | Proc Natl Acad Sci U S A. 2010 Jan 5. [Epub ahead of print] | Lumen expansion driven by hydrostatic pressure occurs during many morphogenetic processes. Althou... | Establishment of a neuroepithelial barrier by Claudin5a is essential for zebrafish brain ventricu... | Microinjection | zebrafish |
| Zhang QY, Zheng K, Ma SS, Tong Y, Luo C | Chinese Science Bulletin. 2010;55:145-152 | β-catenin gene is essential for the formation of normal dorsal axial structure in vertebrates. Re... | Goldfish β-catenin cell-autonomously inhibits the expression of early neural development regulati... | | Goldfish (Carassius auratus auratus) |
| Ishitani T, Hirao T, Suzuki M, Isoda M, Ishitani S, Harigaya K, Kitagawa M, Matsumoto K, Itoh M | Nat Cell Biol. 2010 Jan 31. [Epub ahead of print] | The Notch signalling pathway has a crucial function in determining cell fates in multiple tissues... | Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active tr... | | zebrafish |
| Knowlton MN, Kelly GM | Zebrafish. 2004;1(2):133-44 | Although Xenopus studies have shown that Frizzled 7 activates at least two noncanonical signaling... | Zebrafish Mir antagonizes Frizzled 7-induced gastrulation defects | Microinjection | zebrafish |
| Pei W, Feldman B | Dev Biol. 2009 Feb 1;326(1):201-11. Epub 2008 Nov 19 | Loss of the zebrafish Nodal-related protein Squint causes a spectrum of phenotypes including cycl... | Identification of common and unique modifiers of zebrafish midline bifurcation and cyclopia | Microinjection | zebrafish |
| Jin H, Sood R, Xu J, Zhen F, English MA, Liu PP, Wen Z | Development. 2009 Feb;136(4):647-54. Erratum in: Development. 2009 Apr;136(8):1397 | One unique feature of vertebrate definitive hematopoiesis is the ontogenic switching of hematopoi... | Definitive hematopoietic stem/progenitor cells manifest distinct differentiation output in the ze... | Microinjection | zebrafish |
| Nikolaou N, Watanabe-Asaka T, Gerety S, Distel M, Köster RW, Wilkinson DG | Development. 2009 Aug;136(15):2523-33. Epub 2009 Jun 24 | Previous studies have identified roles of the modulation of Notch activation by Fringe homologues... | Lunatic fringe promotes the lateral inhibition of neurogenesis | Microinjection | zebrafish |
| Passeri MJ, Cinaroglu A, Gao C, Sadler KC | Hepatology. 2009 Feb;49(2):443-52. | Steatosis is the most common consequence of acute alcohol abuse and may predispose to more severe... | Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory e... | Microinjection | zebrafish |
| Bajpai R, Chen DA, Rada-Iglesias A, Zhang J, Xiong Y, Helms J, Chang CP, Zhao Y, Swigut T, Wysock... | Nature. 2010 Feb 3. [Epub ahead of print] | Heterozygous mutations in the gene encoding the CHD (chromodomain helicase DNA-binding domain) me... | CHD7 cooperates with PBAF to control multipotent neural crest formation | Microinjection | Xenopus |
| Chen AY, Zhang EY, Guan W, Cheng F, Kleiboeker S, Yankee TM, Qiu J | Blood. 2009 Oct 27. [Epub ahead of print] | Human parvovirus B19 (B19V) infection shows a strong erythroid tropism and drastically destroys e... | The small 11kDa non-structural protein of human parvovirus B19 plays a key role in inducing apopt... | Endo-Porter | Parvovirus B19 in cell culture: human primary CD36+ erythroid progenitor cells |
| Antic D, Stubbs JL, Suyama K, Kintner C, Scott MP, Axelrod JD | PLoS One. 2010 Feb 2;5(2):e8999 | Left-right asymmetry in vertebrates is initiated in an early embryonic structure called the ventr... | Planar Cell Polarity Enables Posterior Localization of Nodal Cilia and Left-Right Axis Determinat... | Microinjection | Xenopus laevis |
| Shindo A, Hara Y, Yamamoto TS, Ohkura M, Nakai J, Ueno N | PLoS One. 2010 Feb 2;5(2):e8897 | The establishment of cell polarity is crucial for embryonic cells to acquire their proper morphol... | Tissue-Tissue Interaction-Triggered Calcium Elevation Is Required for Cell Polarization during Xe... | Microinjection | Xenopus |
| Xu PF, Zhu KY, Jin Y, Chen Y, Sun XJ, Deng M, Chen SJ, Chen Z, Liu TX | Proc Natl Acad Sci U S A. 2010 Jan 21. [Epub ahead of print] | Dorsal organizer formation is one of the most critical steps in early embryonic development. Seve... | Setdb2 restricts dorsal organizer territory and regulates left-right asymmetry through suppressin... | | zebrafish |
| Nossa CW, Jain P, Tamilselvam B, Gupta VR, Chen LF, Schreiber V, Desnoyers S, Blanke SR | Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19998-20003. Epub 2009 Nov 6 | Modification of eukaryotic proteins is a powerful strategy used by pathogenic bacteria to modulat... | Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori | Endo-Porter | cell culture: AGS cells infected with H. pylori 26695 |
| Hesselson D, Anderson RM, Beinat M, Stainier DY | Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14896-901. Epub 2009 Aug 19 | Pancreatic beta-cells are critical regulators of glucose homeostasis, and they vary dramatically ... | Distinct populations of quiescent and proliferative pancreatic beta-cells identified by HOTcre me... | | zebrafish |
| Morley RH, Lachani K, Keefe D, Gilchrist MJ, Flicek P, Smith JC, Wardle FC | Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3829-34. Epub 2009 Feb 18 | Using chromatin immunoprecipitation combined with genomic microarrays we have identified targets ... | A gene regulatory network directed by zebrafish No tail accounts for its roles in mesoderm format... | Microinjection | zebrafish |
| Marchal L, Luxardi G, Thomé V, Kodjabachian L | Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17437-42. Epub 2009 Sep 28 | Neural induction is the process that initiates nervous system development in vertebrates. Two dis... | BMP inhibition initiates neural induction via FGF signaling and Zic genes | Microinjection | Xenopus |
| Ozhan-Kizil G, Havemann J, Gerberding M | Dev Biol. 2009 Mar 1;327(1):230-9. Epub 2008 Nov 5 | Germ cells are a population of cells that do not differentiate to form somatic tissue but form th... | Germ cells in the crustacean Parhyale hawaiensis depend on Vasa protein for their maintenance but... | | Parhyale hawaiensis |
| Seo S, Baye LM, Schulz NP, Beck JS, Zhang Q, Slusarski DC, Sheffield VC | Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1488-93. Epub 2010 Jan 4 | Bardet-Biedl syndrome (BBS) is a human genetic disorder resulting in obesity, retinal degeneratio... | BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembl... | Microinjection | zebrafish |
| Betancur P, Bronner-Fraser M, Sauka-Spengler T | Proc Natl Acad Sci U S A. 2010 Feb 5. [Epub ahead of print] | The neural crest is a multipotent, stem cell-like population that migrates extensively in the emb... | Genomic code for Sox10 activation reveals a key regulatory enhancer for cranial neural crest | Electroporation | chick embryo |
| Xi Y, Ryan J, Noble S, Yu M, Yilbas AE, Ekker M | Eur J Neurosci. 2010 Feb 5. [Epub ahead of print] | Mutations in the human PTEN-induced kinase 1 (PINK1) gene are linked to recessive familial Parkin... | Impaired dopaminergic neuron development and locomotor function in zebrafish with loss of pink1 f... | | zebrafish |
| Komoike Y, Fujii K, Nishimura A, Hiraki Y, Hayashidani M, Shimojima K, Nishizawa T, Higashi K, Ya... | Genesis. 2010 Feb 9. [Epub ahead of print] | Williams-Beuren syndrome (WBS) is a neurodevelopmental disorder presenting with an elfin-like fac... | Zebrafish gene knockdowns imply roles for human YWHAG in infantile spasms and cardiomegaly | | zebrafish |
| Manning JA, Lewis M, Koblar SA, Kumar S | Cell Death Differ. 2010 Feb 12. [Epub ahead of print] | The centrosome is the primary microtubule organising centre of the cell. It is composed of many p... | An essential function for the centrosomal protein NEDD1 in zebrafish development | Microinjection | zebrafish |
| Wood MJ, Gait MJ, Yin H | Brain. 2010 Feb 11. [Epub ahead of print] | Splice-modulation therapy, whereby molecular manipulation of premessenger RNA splicing is enginee... | RNA-targeted splice-correction therapy for neuromuscular disease | | |
| Soler Bistué AJ, Martín FA, Vozza N, Ha H, Joaquín JC, Zorreguieta A, Tolmasky ME | Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13230-5. Epub 2009 Jul 28 | Inhibition of bacterial gene expression by RNase P-directed cleavage is a promising strategy for ... | Inhibition of aac(6')-Ib-mediated amikacin resistance by nuclease-resistant external guide sequen... | | Escherichia coli AS19 |
| Almeida AD, Wise HM, Hindley CJ, Slevin MK, Hartley RS, Philpott A | Neural Dev. 2010 Jan 4;5(1):1 | ABSTRACT: BACKGROUND: The neural crest is a unique population of cells that arise in the vertebra... | The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis | | Xenopus laevis |
| Morichika K, Kataoka K, Terayama K, Tazaki A, Kinoshita T, Watanabe K, Mochii M | Dev Growth Differ. 2010 Feb;52(2):235-44 | Primordial germ cells (PGCs) in Xenopus embryo are specified in the endodermal cell mass and migr... | Perturbation of Notch/Suppressor of Hairless pathway disturbs migration of primordial germ cells ... | | Xenopus |
| Thummel R, Enright JM, Kassen SC, Montgomery JE, Bailey TJ, Hyde DR | Exp Eye Res. 2010 Feb 9. [Epub ahead of print] | The light-damaged zebrafish retina results in the death of photoreceptor cells and the subsequent... | Pax6a and Pax6b are required at different points in neuronal progenitor cell proliferation during... | Injection then electroporation in vivo | zebrafish |
| Le Pabic P, Scemama JL, Stellwag EJ | Evol Dev. 2010 Jan;12(1):45-60 | Phylogenetic reconstructions suggest that the ancestral osteichthyan Hox paralog group 2 gene com... | Role of Hox PG2 genes in Nile tilapia pharyngeal arch specification: implications for gnathostome... | Microinjection | Nile tilapia |
| Subauste MC, Sansom OJ, Porecha N, Raich N, Du L, Maher JF | Mol Carcinog. 2010 Feb;49(2):105-13. | In the treatment of colon cancer, the development of resistance to apoptosis is a major factor in... | Fem1b, a proapoptotic protein, mediates proteasome inhibitor-induced apoptosis of human colon can... | | cell culture: human colon cancer |
| Sun H, Li D, Chen S, Liu Y, Liao X, Deng W, Li N, Zeng M, Tao D, Ma Y | J Biol Chem. 2010 Feb 5;285(6):4243-50. Epub 2009 Dec 9 | Piwi proteins are required for germ cell proliferation, differentiation, and germ line stem cell ... | Zili inhibits transforming growth factor-beta signaling by interacting with Smad4 | Microinjection | zebrafish |
| Mathew LK, Sengupta S, Franzosa JA, Perry J, La Du J, Andreasen EA, Tanguay RL | J Biol Chem. 2009 Nov 27;284(48):33642-53. Epub 2009 Sep 30 | Zebrafish have the remarkable ability to regenerate body parts including the heart and fins by a ... | Comparative expression profiling reveals an essential role for raldh2 in epimorphic regeneration | | zebrafish |
| Nelsen SM, Christian JL | J Biol Chem. 2009 Oct 2;284(40):27157-66. Epub 2009 Aug 3 | Bone morphogenetic proteins (BMPs) require proteolytic activation by members of the proprotein co... | Site-specific cleavage of BMP4 by furin, PC6, and PC7 | | Xenopus |
| Wan X, Ji W, Mei X, Zhou J, Liu JX, Fang C, Xiao W | PLoS One. 2010 Feb 9;5(2):e9118 | Previous studies indicated that EAF (ELL-associated factor) family members, EAF1 and EAF2/U19, pl... | Negative Feedback Regulation of Wnt4 Signaling by EAF1 and EAF2/U19 | Microinjection | zebrafish |
| Naumann U, Cameroni E, Pruenster M, Mahabaleshwar H, Raz E, Zerwes HG, Rot A, Thelen M | PLoS One. 2010 Feb 11;5(2):e9175 | BACKGROUND: CXCR7 (RDC1), the recently discovered second receptor for CXCL12, is phylogenetically... | CXCR7 Functions as a Scavenger for CXCL12 and CXCL11 | Microinjection | zebrafish |
| Drinjakovic J, Jung H, Campbell DS, Strochlic L, Dwivedy A, Holt CE | Neuron. 2010 Feb 11;65(3):341-357 | Regulated protein degradation via the ubiquitin-proteasome system (UPS) plays a central role in b... | E3 Ligase Nedd4 Promotes Axon Branching by Downregulating PTEN | Microinjection | Xenopus |
| Pearson CG, Osborn DP, Giddings TH Jr, Beales PL, Winey M | J Cell Biol. 2009 Dec 14;187(6):905-20 | Centrioles are the foundation for centrosome and cilia formation. The biogenesis of centrioles is... | Basal body stability and ciliogenesis requires the conserved component Poc1 | | zebrafish |
| Moulton HM, Moulton JD | Biochim Biophys Acta. 2010 Feb 16. [Epub ahead of print] | Exon-skipping efficacy of phosphodiamidate morpholino oligomers (PMOs) or the conjugates of PMOs ... | Morpholinos and Their Peptide Conjugates: Therapeutic Promise and Challenge for Duchenne Muscular... | peptide-coupled versus bare oligo, injected | mouse, monkey, dog |
| Chen HL, Yuh CH, Wu KK | PLoS One. 2010 Feb 19;5(2):e9318 | BACKGROUND: Nestin is expressed in neural progenitor cells (NPC) of developing brain. Despite its... | Nestin Is Essential for Zebrafish Brain and Eye Development through Control of Progenitor Cell Ap... | Microinjection | zebrafish |
| McLeish JA, Chico TJ, Taylor HB, Tucker C, Donaldson K, Brown SB | Thromb Haemost. 2010 Feb 19;103(4). [Epub ahead of print] | Low mass ambient exposure to airborne particles is associated with atherothrombotic events that m... | Skin exposure to micro- and nano-particles can cause haemostasis in zebrafish larvae | | zebrafish |
