Publications - Page 63
| Authors | Citation | Abstract | Title | Delivery Method | Organism |
| Chablais F, Jazwinska A | Development. 2010 Mar;137(6):871-9 | In mammals, the loss of a limb is irreversible. By contrast, urodele amphibians and teleost fish ... | IGF signaling between blastema and wound epidermis is required for fin regeneration | | zebrafish |
| Verbruggen V, Ek O, Georlette D, Delporte F, Von Berg V, Detry N, Biemar F, Coutinho P, Martial J... | J Biol Chem. 2010 Feb 22. [Epub ahead of print] | Pax6 is a well conserved transcription factor that contains two DNA binding domains, a paired dom... | The Pax6b homeodomain is dispensable for pancreatic endocrine cell differentiation in zebrafish | Microinjection | zebrafish |
| O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, N... | J Clin Invest. 2010 Feb 22. pii: 40076. doi: 10.1172/JCI40076. [Epub ahead of print] | The autosomal recessive kidney disease nephronophthisis (NPHP) constitutes the most frequent gene... | Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronop... | | zebrafish |
| Cruz C, Maegawa S, Weinberg ES, Wilson SW, Dawid IB, Kudoh T | Proc Natl Acad Sci U S A. 2010 Feb 8. [Epub ahead of print] | In vertebrates, Evx homeodomain transcription factor-encoding genes are expressed in the posterio... | Induction and patterning of trunk and tail neural ectoderm by the homeobox gene eve1 in zebrafish... | | |
| Kissa K, Herbomel P | Nature. 2010 Feb 14. [Epub ahead of print] | The ontogeny of haematopoietic stem cells (HSCs) during embryonic development is still highly deb... | Blood stem cells emerge from aortic endothelium by a novel type of cell transition | | zebrafish |
| Christen B, Robles V, Raya M, Paramonov I, Belmonte JC | BMC Biol. 2010 Jan 20;8:5 | ABSTRACT: BACKGROUND: Dedifferentiation occurs naturally in mature cell types during epimorphic r... | Regeneration and reprogramming compared | Injection then electroporation in vivo | zebrafish |
| Okamoto M, Van Stry M, Chung L, Koyanagi M, Sun X, Suzuki Y, Ohara O, Kitamura H, Hijikata A, Kub... | Nat Immunol. 2009 Aug;10(8):872-9. Epub 2009 Jun 28. | T helper type 2 (TH2) bias, which is the propensity of naive CD4+ T cells to differentiate into i... | Mina, an Il4 repressor, controls T helper type 2 bias | Endo-Porter | cell culture: C57BL/6 CD4+ T cells |
| Ren X, Gomez GA, Zhang B, Lin S | Blood. 2010 Feb 25. [Epub ahead of print] | Recent lineage studies suggest that hematopoietic stem cells (HSCs) may be derived from endotheli... | Scl isoforms act downstream of etsrp to specify angioblasts and definitive hematopoietic stem cel... | | zebrafish |
| Nolte C, Rastegar M, Amores A, Bouchard M, Grote D, Maas R, Kovacs EN, Postlethwait J, Rambaldi I... | Dev Biol. 2006 Nov 15;299(2):582-93. Epub 2006 Aug 30 | The antero-posterior (AP) and dorso-ventral (DV) patterning of the neural tube is controlled in p... | Stereospecificity and PAX6 function direct Hoxd4 neural enhancer activity along the antero-poster... | Microinjection | zebrafish |
| Delcroix M, Riley LW | Pharmaceuticals. 2010;3:448-70 | Viral diseases affect hundreds of millions of people worldwide, and the few
available drugs to t... | Cell-Penetrating Peptides for Antiviral Drug Development | peptide-coupled | |
| Shi X, Zhou B | Toxicol Sci. 2010 Mar 3. [Epub ahead of print] | Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant and causes oxidative stress, a... | The Role of Nrf2 and MAPK Pathways in PFOS-induced Oxidative Stress in Zebrafish Embryos | | zebrafish |
| Park BY, Saint-Jeannet JP | Dev Dyn. 2010 Mar 3. [Epub ahead of print] | The transcription factor Sox9 has been implicated in inner ear formation in several species. To i... | Long-term consequences of Sox9 depletion on inner ear development | Microinjection | Xenopus |
| Fjose A, Zhao XF | New Biotechnology. 2010 Feb 26 [Epub ahead of print] | The microRNA (miRNA) pathway and the phenomenon of RNA interference (RNAi) have similar mechanism... | Exploring microRNA functions in zebrafish | | zebrafish |
| Li H, Kloosterman W, Fekete DM | J Neurosci. 2010 Mar 3;30(9):3254-63 | Members of the microRNA (miRNA) 183 family (miR-183, miR-96, and miR-182) are expressed abundantl... | MicroRNA-183 Family Members Regulate Sensorineural Fates in the Inner Ear | | zebrafish |
| Zhang J, Stein DA, Timoney PJ, Balasuriya UB | Virus Res. 2010 Mar 2. [Epub ahead of print] | A significant consequence of equine arteritis virus (EAV) infection of horses is persistence of t... | Curing of HeLa Cells Persistently Infected with Equine Arteritis Virus by a Peptide-conjugated Mo... | peptide-coupled | cell culture: HeLa with equine arteritis viral infection |
| Guiral EC, Faas L, Pownall ME | Dev Biol. 2010 Mar 3. [Epub ahead of print] | In vertebrates, there are two related genes, Sulf1 and Sulf2 that code for extracellular heparan ... | Neural crest migration requires the activity of the extracellular sulfatases XtSulf1 and XtSulf2 | | Xenopus |
| Hudak LM, Lunt S, Chang CH, Winkler E, Flammer H, Lindsey M, Perkins B | Invest Ophthalmol Vis Sci. 2010 Mar 5. [Epub ahead of print] | Purpose: Jeune's Asphyxiating Thoracic Dystrophy (JATD) is an autosomal recessive disorder with s... | The Intraflagellar Transport Protein Ift80 is essential for Photoreceptor Survival in a Zebrafish... | Microinjection | zebrafish |
| Cao Y, Oswald F, Wacker SA, Bundschu K, Knöchel W | J Biol Chem. 2010 Mar 12;285(11):8408-8421. Epub 2010 Jan 11 | Xenopus Oct25 is a POU family subclass V (POU-V) transcription factor with a distinct domain stru... | Reversal of Xenopus Oct25 Function by Disruption of the POU Domain Structure | Microinjection | Xenopus |
| Tsukada Y, Ishitani T, Nakayama KI | Genes Dev. 2010 Mar 1;24(5):432-7 | Methylation of histone H3 Lys 9 and Lys 27 (H3K9 and H3K27) is associated with transcriptional si... | KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development | | zebrafish |
| Tobin DM, Vary JC Jr, Ray JP, Walsh GS, Dunstan SJ, Bang ND, Hagge DA, Khadge S, King MC, Hawn TR... | Cell. 2010 Mar 5;140(5):717-730 | Exposure to Mycobacterium tuberculosis produces varied early outcomes, ranging from resistance to... | The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and Humans | Microinjection | zebrafish |
| Silvestre DC, Gil GA, Tomasini N, Bussolino DF, Caputto BL | PLoS One. 2010 Mar 4;5(3):e9544 | BACKGROUND: We have previously shown that the transcription factor c-Fos is also capable of assoc... | Growth of Peripheral and Central Nervous System Tumors Is Supported by Cytoplasmic c-Fos in Human... | Osmotic pump (Alzet) though cannula to right caudate putamen | mice: NPcis on C57BL/6J background |
| Blythe SA, Reid CD, Kessler DS, Klein PS | Dev Dyn. 2009 Jun;238(6):1422-32 | Chromatin immunoprecipitation (ChIP) is a powerful method for analyzing the interaction of regula... | Chromatin immunoprecipitation in early Xenopus laevis embryos | Microinjection | Xenopus laevis |
| Park SJ, Jung SH, Jogeswar G, Ryoo HM, Yook JI, Choi HS, Rhee Y, Kim CH, Lim SK | Bone. 2010 Mar 6. [Epub ahead of print] | Osteoblasts originate from mesenchymal stem cells by the coordinated activities of different sign... | The transcription factor Snail regulates osteogenic differentiation by repressing Runx2 expressio... | | zebrafish |
| Hartwig S, Ho J, Pandey P, Macisaac K, Taglienti M, Xiang M, Alterovitz G, Ramoni M, Fraenkel E, ... | Development. 2010 Apr;137(7):1189-203 | The Wilms' tumor suppressor 1 (WT1) gene encodes a DNA- and RNA-binding protein that plays an ess... | Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during ... | Vivo-Morpholino | Mouse kidney explants, embryonic |
| van Eekelen M, Runtuwene V, Overvoorde J, den Hertog J | Dev Biol. 2010 Feb 24. [Epub ahead of print] | Convergence and extension (C&E) cell movements are essential to shape the body axis during verteb... | RPTPalpha and PTPepsilon signaling via Fyn/Yes and RhoA is essential for zebrafish convergence an... | | zebrafish |
| Tran U, Zakin L, Schweickert A, Agrawal R, Döger R, Blum M, De Robertis EM, Wessely O | Development. 2010 Apr;137(7):1107-16 | The RNA-binding protein Bicaudal C is an important regulator of embryonic development in C. elega... | The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 ac... | | Xenopus |
| Kim MS, Yoon SK, Bollig F, Kitagaki J, Hur W, Whye NJ, Wu YP, Rivera MN, Park JY, Kim HS, Malik K... | J Biol Chem. 2010 Mar 10. [Epub ahead of print] | Mammalian kidney development requires the functions of the Wilms tumor gene WT1 and the WNT/beta-... | A novel Wilms Tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway | | zebrafish |
| Jing L, Lefebvre JL, Gordon LR, Granato M | Neuron. 2009 Mar 12;61(5):721-33 | Early during neuromuscular development, acetylcholine receptors (AChRs) accumulate at the center ... | Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK r... | Microinjection | zebrafish |
| Zhao X, He X, Han X, Yu Y, Ye F, Chen Y, Hoang T, Xu X, Mi QS, Xin M, Wang F, Appel B, Lu QR | Neuron. 2010 Mar 11;65(5):612-626 | MicroRNAs (miRNAs) regulate various biological processes, but evidence for miRNAs that control th... | MicroRNA-Mediated Control of Oligodendrocyte Differentiation | | zebrafish |
| Ito T, Ando H, Suzuki T, Ogura T, Hotta K, Imamura Y, Yamaguchi Y, Handa H | Science. 2010 Mar 12;327(5971):1345-50 | Half a century ago, thalidomide was widely prescribed to pregnant women as a sedative but was fou... | Identification of a primary target of thalidomide teratogenicity | Microinjection | zebrafish |
| Quintana FJ, Iglesias AH, Farez MF, Caccamo M, Burns EJ, Kassam N, Oukka M, Weiner HL | PLoS One. 2010 Mar 5;5(3):e9478 | BACKGROUND: Jawed vertebrates generate their immune-receptor repertoire by a recombinatorial mech... | Adaptive autoimmunity and foxp3-based immunoregulation in zebrafish | Microinjection | zebrafish |
| Neumann-Haefelin E, Kramer-Zucker A, Slanchev K, Hartleben B, Noutsou F, Martin K, Wanner N, Ritt... | Hum Mol Genet. 2010 Mar 16. [Epub ahead of print] | Mutations of the immunoglobulin superfamily proteins nephrin and Neph1 lead to congenital nephrot... | A Model organism approach: Defining the role of Neph proteins as regulators of neuron and kidney ... | | zebrafish |
| Wang Q, Yin H, Camelliti P, Betts C, Moulton H, Lee H, Saleh AF, Gait MJ, Wood MJ | J Gene Med. 2010 Mar 16. [Epub ahead of print] | BACKGROUND: Targeted splice modulation of pre-mRNA transcripts by antisense oligonucleotides (AOs... | In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping ac... | peptide-coupled | mdk mice, H2K mdx cells |
| Sadikot T, Hammond CR, Ferrari MB | Dev Dyn. 2010 Mar 16;239(4):1124-1135. [Epub ahead of print] | The N-terminus of telethonin forms a unique structure linking two titin N-termini at the Z-disc. ... | Distinct roles for telethonin N-versus C-terminus in sarcomere assembly and maintenance | | Xenopus |
| Salanga MC, Meadows SM, Myers CT, Krieg PA | Dev Dyn. 2010 Mar 16;239(4):1178-1187. [Epub ahead of print] | Transcription factors of the ETS family are important regulators of endothelial and hematopoietic... | ETS family protein ETV2 is required for initiation of the endothelial lineage but not the hematop... | | Xenopus |
| Nagashima M, Saito J, Mawatari K, Mori Y, Matsukawa T, Koriyama Y, Kato S | Adv Exp Med Biol. 2010;664:517-24 | Recently, we cloned a photoreceptor-specific purpurin cDNA from axotomized goldfish retina. In th... | A hypoplastic retinal lamination in the purpurin knock down embryo in zebrafish | | zebrafish |
| Hsu RJ, Lin CY, Hoi HS, Zheng SK, Lin CC, Tsai HJ | Nucleic Acids Res. 2010 Mar 17. [Epub ahead of print] | A strong, negative cis-element located at the first intron +502/+835 (I300) of zebrafish myf5 has... | Novel intronic microRNA represses zebrafish myf5 promoter activity through silencing dickkopf-3 g... | Microinjection | zebrafish |
| Nishino A, Okamura Y, Piscopo S, Brown ER | BMC Neurosci. 2010 Jan 19;11:6 | BACKGROUND: Rhythmic motor patterns for locomotion in vertebrates are generated in spinal cord ne... | A glycine receptor is involved in the organization of swimming movements in an invertebrate chord... | Microinjection | Ciona intestinalis |
| Anantpadma M, Stein DA, Vrati S | J Antimicrob Chemother. 2010 Mar 18. [Epub ahead of print] | Background Japanese encephalitis virus (JEV) has a significant impact on public health throughout... | Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-con... | peptide-coupled | mice and cell culture: Vero, Neuro2A and J774E cells |
| Ptaszynska MM, Pendrak ML, Stracke ML, Roberts DD | Mol Cancer Res. 2010 Mar;8(3):309-21. Epub 2010 Mar 2 | Important roles for vascular endothelial growth factor (VEGF) and autotaxin (ATX) have been estab... | Autotaxin Signaling via Lysophosphatidic Acid Receptors Contributes to Vascular Endothelial Growt... | Endo-Porter | Cell Culture: human umbilical vein endothelial cells (HUVECs) |
| D'Autilia S, Broccoli V, Barsacchi G, Andreazzoli M | Proc Natl Acad Sci U S A. 2010 Mar 22. [Epub ahead of print] | In the developing central nervous system, the cell cycle clock plays a crucial role in determinin... | Xenopus Bsx links daily cell cycle rhythms and pineal photoreceptor fate | Microinjection | Xenopus |
| Morita H, Nandadasa S, Yamamoto TS, Terasaka-Iioka C, Wylie C, Ueno N | Development. 2010 Apr;137(8):1315-25 | Neural tube formation is one of the most dynamic morphogenetic processes of vertebrate developmen... | Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of ... | Microinjection | Xenopus |
| Pretorius PR, Baye LM, Nishimura DY, Searby CC, Bugge K, Yang B, Mullins RF, Stone EM, Sheffield ... | PLoS Genet. 2010 Mar 19;6(3):e1000884 | Bardet-Biedl Syndrome (BBS) is a heterogeneous syndromic form of retinal degeneration. We have id... | Identification and Functional Analysis of the Vision-Specific BBS3 (ARL6) Long Isoform | Microinjection | zebrafish |
| Fletcher S, Adams AM, Johnsen RD, Greer K, Moulton HM, Wilton SD | Mol Ther. 2010 Mar 23. [Epub ahead of print] |
Antisense oligomer-induced manipulation of dystrophin pre-mRNA processing can remove exons carr... | Dystrophin Isoform Induction In Vivo by Antisense-mediated Alternative Splicing | peptide-coupled | mice |
| Mangos S, Lam PY, Zhao A, Liu Y, Mudumana S, Vasilyev A, Liu A, Drummond IA | Dis Model Mech. 2010 Mar 24. [Epub ahead of print] | Mutations in polycystin1 (PKD1) account for the majority of autosomal dominant polycystic kidney ... | The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formation | Microinjection | zebrafish |
| Ren B, Deng Y, Mukhopadhyay A, Lanahan AA, Zhuang ZW, Moodie KL, Mulligan-Kehoe MJ, Byzova TV, Pe... | J Clin Invest. 2010 Mar 8. [Epub ahead of print] | Arterial morphogenesis is an important and poorly understood process. In particular, the signalin... | ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafish | Microinjection | zebrafish |
| Telfer WR, Busta AS, Bonnemann CG, Feldman EL, Dowling JJ | Hum Mol Genet. 2010 Mar 25. [Epub ahead of print] | Collagen VI is an integral part of the skeletal muscle extracellular matrix, providing mechanical... | Zebrafish Models of Collagen VI Related Myopathies | Microinjection | zebrafish |
| Chopra SS, Stroud DM, Watanabe H, Bennett JS, Burns CG, Wells KS, Yang T, Zhong TP, Roden DM | Circ Res. 2010 Mar 25. [Epub ahead of print] | Rationale: Voltage-gated sodium channels initiate action potentials in excitable tissues. Mice in... | Voltage-Gated Sodium Channels Are Required for Heart Development in Zebrafish | Microinjection | zebrafish |
| Li HY, Bourdelas A, Carron C, Shi DL | Mech Dev. 2010 Mar 22. [Epub ahead of print] | RNA-binding proteins play an important role to post-transcriptionally regulate gene expression. D... | The RNA-binding protein Seb4/RBM24 is a direct target of MyoD and is required for myogenesis duri... | Microinjection | Xenopus laevis |
| Tachibana K, Mori M, Matsuhira T, Karino T, Inagaki T, Nagayama A, Nishiyama A, Hara M, Kishimoto... | Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5006-11. Epub 2010 Feb 25 | Initiation of DNA replication in eukaryotic cells is controlled through an ordered assembly of pr... | Initiation of DNA replication after fertilization is regulated by p90Rsk at pre-RC/pre-IC transit... | Microinjection | Starfish Asterina pectinifera |