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Publications Database

Publications - Page 63
AuthorsCitationAbstractTitleDelivery MethodOrganism
Chablais F, Jazwinska ADevelopment. 2010 Mar;137(6):871-9In mammals, the loss of a limb is irreversible. By contrast, urodele amphibians and teleost fish ...IGF signaling between blastema and wound epidermis is required for fin regenerationzebrafish
Verbruggen V, Ek O, Georlette D, Delporte F, Von Berg V, Detry N, Biemar F, Coutinho P, Martial J...J Biol Chem. 2010 Feb 22. [Epub ahead of print]Pax6 is a well conserved transcription factor that contains two DNA binding domains, a paired dom...The Pax6b homeodomain is dispensable for pancreatic endocrine cell differentiation in zebrafishMicroinjectionzebrafish
O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, N...J Clin Invest. 2010 Feb 22. pii: 40076. doi: 10.1172/JCI40076. [Epub ahead of print]The autosomal recessive kidney disease nephronophthisis (NPHP) constitutes the most frequent gene...Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronop...zebrafish
Cruz C, Maegawa S, Weinberg ES, Wilson SW, Dawid IB, Kudoh TProc Natl Acad Sci U S A. 2010 Feb 8. [Epub ahead of print]In vertebrates, Evx homeodomain transcription factor-encoding genes are expressed in the posterio...Induction and patterning of trunk and tail neural ectoderm by the homeobox gene eve1 in zebrafish...
Kissa K, Herbomel PNature. 2010 Feb 14. [Epub ahead of print]The ontogeny of haematopoietic stem cells (HSCs) during embryonic development is still highly deb...Blood stem cells emerge from aortic endothelium by a novel type of cell transitionzebrafish
Christen B, Robles V, Raya M, Paramonov I, Belmonte JCBMC Biol. 2010 Jan 20;8:5ABSTRACT: BACKGROUND: Dedifferentiation occurs naturally in mature cell types during epimorphic r...Regeneration and reprogramming comparedInjection then electroporation in vivozebrafish
Okamoto M, Van Stry M, Chung L, Koyanagi M, Sun X, Suzuki Y, Ohara O, Kitamura H, Hijikata A, Kub...Nat Immunol. 2009 Aug;10(8):872-9. Epub 2009 Jun 28.T helper type 2 (TH2) bias, which is the propensity of naive CD4+ T cells to differentiate into i...Mina, an Il4 repressor, controls T helper type 2 biasEndo-Portercell culture: C57BL/6 CD4+ T cells
Ren X, Gomez GA, Zhang B, Lin SBlood. 2010 Feb 25. [Epub ahead of print]Recent lineage studies suggest that hematopoietic stem cells (HSCs) may be derived from endotheli...Scl isoforms act downstream of etsrp to specify angioblasts and definitive hematopoietic stem cel...zebrafish
Nolte C, Rastegar M, Amores A, Bouchard M, Grote D, Maas R, Kovacs EN, Postlethwait J, Rambaldi I...Dev Biol. 2006 Nov 15;299(2):582-93. Epub 2006 Aug 30The antero-posterior (AP) and dorso-ventral (DV) patterning of the neural tube is controlled in p...Stereospecificity and PAX6 function direct Hoxd4 neural enhancer activity along the antero-poster...Microinjectionzebrafish
Delcroix M, Riley LWPharmaceuticals. 2010;3:448-70Viral diseases affect hundreds of millions of people worldwide, and the few available drugs to t...Cell-Penetrating Peptides for Antiviral Drug Developmentpeptide-coupled
Shi X, Zhou BToxicol Sci. 2010 Mar 3. [Epub ahead of print]Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant and causes oxidative stress, a...The Role of Nrf2 and MAPK Pathways in PFOS-induced Oxidative Stress in Zebrafish Embryoszebrafish
Park BY, Saint-Jeannet JPDev Dyn. 2010 Mar 3. [Epub ahead of print]The transcription factor Sox9 has been implicated in inner ear formation in several species. To i...Long-term consequences of Sox9 depletion on inner ear developmentMicroinjectionXenopus
Fjose A, Zhao XFNew Biotechnology. 2010 Feb 26 [Epub ahead of print]The microRNA (miRNA) pathway and the phenomenon of RNA interference (RNAi) have similar mechanism...Exploring microRNA functions in zebrafishzebrafish
Li H, Kloosterman W, Fekete DMJ Neurosci. 2010 Mar 3;30(9):3254-63Members of the microRNA (miRNA) 183 family (miR-183, miR-96, and miR-182) are expressed abundantl...MicroRNA-183 Family Members Regulate Sensorineural Fates in the Inner Earzebrafish
Zhang J, Stein DA, Timoney PJ, Balasuriya UBVirus Res. 2010 Mar 2. [Epub ahead of print]A significant consequence of equine arteritis virus (EAV) infection of horses is persistence of t...Curing of HeLa Cells Persistently Infected with Equine Arteritis Virus by a Peptide-conjugated Mo...peptide-coupledcell culture: HeLa with equine arteritis viral infection
Guiral EC, Faas L, Pownall MEDev Biol. 2010 Mar 3. [Epub ahead of print]In vertebrates, there are two related genes, Sulf1 and Sulf2 that code for extracellular heparan ...Neural crest migration requires the activity of the extracellular sulfatases XtSulf1 and XtSulf2Xenopus
Hudak LM, Lunt S, Chang CH, Winkler E, Flammer H, Lindsey M, Perkins BInvest Ophthalmol Vis Sci. 2010 Mar 5. [Epub ahead of print]Purpose: Jeune's Asphyxiating Thoracic Dystrophy (JATD) is an autosomal recessive disorder with s...The Intraflagellar Transport Protein Ift80 is essential for Photoreceptor Survival in a Zebrafish...Microinjectionzebrafish
Cao Y, Oswald F, Wacker SA, Bundschu K, Knöchel WJ Biol Chem. 2010 Mar 12;285(11):8408-8421. Epub 2010 Jan 11Xenopus Oct25 is a POU family subclass V (POU-V) transcription factor with a distinct domain stru...Reversal of Xenopus Oct25 Function by Disruption of the POU Domain StructureMicroinjectionXenopus
Tsukada Y, Ishitani T, Nakayama KIGenes Dev. 2010 Mar 1;24(5):432-7Methylation of histone H3 Lys 9 and Lys 27 (H3K9 and H3K27) is associated with transcriptional si...KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain developmentzebrafish
Tobin DM, Vary JC Jr, Ray JP, Walsh GS, Dunstan SJ, Bang ND, Hagge DA, Khadge S, King MC, Hawn TR...Cell. 2010 Mar 5;140(5):717-730Exposure to Mycobacterium tuberculosis produces varied early outcomes, ranging from resistance to...The lta4h Locus Modulates Susceptibility to Mycobacterial Infection in Zebrafish and HumansMicroinjectionzebrafish
Silvestre DC, Gil GA, Tomasini N, Bussolino DF, Caputto BLPLoS One. 2010 Mar 4;5(3):e9544BACKGROUND: We have previously shown that the transcription factor c-Fos is also capable of assoc...Growth of Peripheral and Central Nervous System Tumors Is Supported by Cytoplasmic c-Fos in Human...Osmotic pump (Alzet) though cannula to right caudate putamenmice: NPcis on C57BL/6J background
Blythe SA, Reid CD, Kessler DS, Klein PSDev Dyn. 2009 Jun;238(6):1422-32Chromatin immunoprecipitation (ChIP) is a powerful method for analyzing the interaction of regula...Chromatin immunoprecipitation in early Xenopus laevis embryosMicroinjectionXenopus laevis
Park SJ, Jung SH, Jogeswar G, Ryoo HM, Yook JI, Choi HS, Rhee Y, Kim CH, Lim SKBone. 2010 Mar 6. [Epub ahead of print]Osteoblasts originate from mesenchymal stem cells by the coordinated activities of different sign...The transcription factor Snail regulates osteogenic differentiation by repressing Runx2 expressio...zebrafish
Hartwig S, Ho J, Pandey P, Macisaac K, Taglienti M, Xiang M, Alterovitz G, Ramoni M, Fraenkel E, ...Development. 2010 Apr;137(7):1189-203The Wilms' tumor suppressor 1 (WT1) gene encodes a DNA- and RNA-binding protein that plays an ess...Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during ...Vivo-MorpholinoMouse kidney explants, embryonic
van Eekelen M, Runtuwene V, Overvoorde J, den Hertog JDev Biol. 2010 Feb 24. [Epub ahead of print]Convergence and extension (C&E) cell movements are essential to shape the body axis during verteb...RPTPalpha and PTPepsilon signaling via Fyn/Yes and RhoA is essential for zebrafish convergence an...zebrafish
Tran U, Zakin L, Schweickert A, Agrawal R, Döger R, Blum M, De Robertis EM, Wessely ODevelopment. 2010 Apr;137(7):1107-16The RNA-binding protein Bicaudal C is an important regulator of embryonic development in C. elega...The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 ac...Xenopus
Kim MS, Yoon SK, Bollig F, Kitagaki J, Hur W, Whye NJ, Wu YP, Rivera MN, Park JY, Kim HS, Malik K...J Biol Chem. 2010 Mar 10. [Epub ahead of print]Mammalian kidney development requires the functions of the Wilms tumor gene WT1 and the WNT/beta-...A novel Wilms Tumor 1 (WT1) target gene negatively regulates the WNT signaling pathwayzebrafish
Jing L, Lefebvre JL, Gordon LR, Granato MNeuron. 2009 Mar 12;61(5):721-33Early during neuromuscular development, acetylcholine receptors (AChRs) accumulate at the center ...Wnt signals organize synaptic prepattern and axon guidance through the zebrafish unplugged/MuSK r...Microinjectionzebrafish
Zhao X, He X, Han X, Yu Y, Ye F, Chen Y, Hoang T, Xu X, Mi QS, Xin M, Wang F, Appel B, Lu QRNeuron. 2010 Mar 11;65(5):612-626MicroRNAs (miRNAs) regulate various biological processes, but evidence for miRNAs that control th...MicroRNA-Mediated Control of Oligodendrocyte Differentiationzebrafish
Ito T, Ando H, Suzuki T, Ogura T, Hotta K, Imamura Y, Yamaguchi Y, Handa HScience. 2010 Mar 12;327(5971):1345-50Half a century ago, thalidomide was widely prescribed to pregnant women as a sedative but was fou...Identification of a primary target of thalidomide teratogenicityMicroinjectionzebrafish
Quintana FJ, Iglesias AH, Farez MF, Caccamo M, Burns EJ, Kassam N, Oukka M, Weiner HLPLoS One. 2010 Mar 5;5(3):e9478BACKGROUND: Jawed vertebrates generate their immune-receptor repertoire by a recombinatorial mech...Adaptive autoimmunity and foxp3-based immunoregulation in zebrafishMicroinjectionzebrafish
Neumann-Haefelin E, Kramer-Zucker A, Slanchev K, Hartleben B, Noutsou F, Martin K, Wanner N, Ritt...Hum Mol Genet. 2010 Mar 16. [Epub ahead of print]Mutations of the immunoglobulin superfamily proteins nephrin and Neph1 lead to congenital nephrot...A Model organism approach: Defining the role of Neph proteins as regulators of neuron and kidney ...zebrafish
Wang Q, Yin H, Camelliti P, Betts C, Moulton H, Lee H, Saleh AF, Gait MJ, Wood MJJ Gene Med. 2010 Mar 16. [Epub ahead of print]BACKGROUND: Targeted splice modulation of pre-mRNA transcripts by antisense oligonucleotides (AOs...In vitro evaluation of novel antisense oligonucleotides is predictive of in vivo exon skipping ac...peptide-coupledmdk mice, H2K mdx cells
Sadikot T, Hammond CR, Ferrari MBDev Dyn. 2010 Mar 16;239(4):1124-1135. [Epub ahead of print]The N-terminus of telethonin forms a unique structure linking two titin N-termini at the Z-disc. ...Distinct roles for telethonin N-versus C-terminus in sarcomere assembly and maintenanceXenopus
Salanga MC, Meadows SM, Myers CT, Krieg PADev Dyn. 2010 Mar 16;239(4):1178-1187. [Epub ahead of print]Transcription factors of the ETS family are important regulators of endothelial and hematopoietic...ETS family protein ETV2 is required for initiation of the endothelial lineage but not the hematop...Xenopus
Nagashima M, Saito J, Mawatari K, Mori Y, Matsukawa T, Koriyama Y, Kato SAdv Exp Med Biol. 2010;664:517-24Recently, we cloned a photoreceptor-specific purpurin cDNA from axotomized goldfish retina. In th...A hypoplastic retinal lamination in the purpurin knock down embryo in zebrafishzebrafish
Hsu RJ, Lin CY, Hoi HS, Zheng SK, Lin CC, Tsai HJNucleic Acids Res. 2010 Mar 17. [Epub ahead of print]A strong, negative cis-element located at the first intron +502/+835 (I300) of zebrafish myf5 has...Novel intronic microRNA represses zebrafish myf5 promoter activity through silencing dickkopf-3 g...Microinjectionzebrafish
Nishino A, Okamura Y, Piscopo S, Brown ERBMC Neurosci. 2010 Jan 19;11:6BACKGROUND: Rhythmic motor patterns for locomotion in vertebrates are generated in spinal cord ne...A glycine receptor is involved in the organization of swimming movements in an invertebrate chord...MicroinjectionCiona intestinalis
Anantpadma M, Stein DA, Vrati SJ Antimicrob Chemother. 2010 Mar 18. [Epub ahead of print]Background Japanese encephalitis virus (JEV) has a significant impact on public health throughout...Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-con...peptide-coupledmice and cell culture: Vero, Neuro2A and J774E cells
Ptaszynska MM, Pendrak ML, Stracke ML, Roberts DDMol Cancer Res. 2010 Mar;8(3):309-21. Epub 2010 Mar 2Important roles for vascular endothelial growth factor (VEGF) and autotaxin (ATX) have been estab...Autotaxin Signaling via Lysophosphatidic Acid Receptors Contributes to Vascular Endothelial Growt...Endo-PorterCell Culture: human umbilical vein endothelial cells (HUVECs)
D'Autilia S, Broccoli V, Barsacchi G, Andreazzoli MProc Natl Acad Sci U S A. 2010 Mar 22. [Epub ahead of print]In the developing central nervous system, the cell cycle clock plays a crucial role in determinin...Xenopus Bsx links daily cell cycle rhythms and pineal photoreceptor fateMicroinjectionXenopus
Morita H, Nandadasa S, Yamamoto TS, Terasaka-Iioka C, Wylie C, Ueno NDevelopment. 2010 Apr;137(8):1315-25Neural tube formation is one of the most dynamic morphogenetic processes of vertebrate developmen...Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of ...MicroinjectionXenopus
Pretorius PR, Baye LM, Nishimura DY, Searby CC, Bugge K, Yang B, Mullins RF, Stone EM, Sheffield ...PLoS Genet. 2010 Mar 19;6(3):e1000884Bardet-Biedl Syndrome (BBS) is a heterogeneous syndromic form of retinal degeneration. We have id...Identification and Functional Analysis of the Vision-Specific BBS3 (ARL6) Long IsoformMicroinjectionzebrafish
Fletcher S, Adams AM, Johnsen RD, Greer K, Moulton HM, Wilton SDMol Ther. 2010 Mar 23. [Epub ahead of print] Antisense oligomer-induced manipulation of dystrophin pre-mRNA processing can remove exons carr...Dystrophin Isoform Induction In Vivo by Antisense-mediated Alternative Splicingpeptide-coupledmice
Mangos S, Lam PY, Zhao A, Liu Y, Mudumana S, Vasilyev A, Liu A, Drummond IADis Model Mech. 2010 Mar 24. [Epub ahead of print]Mutations in polycystin1 (PKD1) account for the majority of autosomal dominant polycystic kidney ...The ADPKD genes pkd1a/b and pkd2 regulate extracellular matrix formationMicroinjectionzebrafish
Ren B, Deng Y, Mukhopadhyay A, Lanahan AA, Zhuang ZW, Moodie KL, Mulligan-Kehoe MJ, Byzova TV, Pe...J Clin Invest. 2010 Mar 8. [Epub ahead of print]Arterial morphogenesis is an important and poorly understood process. In particular, the signalin...ERK1/2-Akt1 crosstalk regulates arteriogenesis in mice and zebrafishMicroinjectionzebrafish
Telfer WR, Busta AS, Bonnemann CG, Feldman EL, Dowling JJHum Mol Genet. 2010 Mar 25. [Epub ahead of print]Collagen VI is an integral part of the skeletal muscle extracellular matrix, providing mechanical...Zebrafish Models of Collagen VI Related MyopathiesMicroinjectionzebrafish
Chopra SS, Stroud DM, Watanabe H, Bennett JS, Burns CG, Wells KS, Yang T, Zhong TP, Roden DMCirc Res. 2010 Mar 25. [Epub ahead of print]Rationale: Voltage-gated sodium channels initiate action potentials in excitable tissues. Mice in...Voltage-Gated Sodium Channels Are Required for Heart Development in ZebrafishMicroinjectionzebrafish
Li HY, Bourdelas A, Carron C, Shi DLMech Dev. 2010 Mar 22. [Epub ahead of print]RNA-binding proteins play an important role to post-transcriptionally regulate gene expression. D...The RNA-binding protein Seb4/RBM24 is a direct target of MyoD and is required for myogenesis duri...MicroinjectionXenopus laevis
Tachibana K, Mori M, Matsuhira T, Karino T, Inagaki T, Nagayama A, Nishiyama A, Hara M, Kishimoto...Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5006-11. Epub 2010 Feb 25Initiation of DNA replication in eukaryotic cells is controlled through an ordered assembly of pr...Initiation of DNA replication after fertilization is regulated by p90Rsk at pre-RC/pre-IC transit...MicroinjectionStarfish Asterina pectinifera

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