Publications - Page 1
| Authors | Citation | Abstract | Title | Delivery Method | Organism |
|---|
| Kipshidze, N., Keane, E., Stein, D., Chawla, P., Skrinska, V., Shandar, L.R., Komorowski, R., Hau... | XXIst Congress of the European Society of Cardiology, Ed. Francisco Navarro-Lopez, Monduzzi Edito... | | Local delivery of antisense phosphorodiamidate morpholino oligomer; Resten-NG inhibits myointimal... | | |
| Kim K, Nakagawa H, Fei P, Rustgi AK, El-Deiry WS | Cell Death Differ. 2004 May;11(5):583-7. No abstract available. | | Targeting Bcl-x(L) in esophageal squamous cancer to sensitize to chemotherapy plus TRAIL-induced ... | Scrape Delivery | cell culture: human HCE4, TE3, and TE5 cells. |
| Devi G | Cancer Gene Therapy, 2003, vol. 10, no. SUPP/1, pp. 9 | | In Vivo Efficacy of Phosphorodiamidate Morpholino-Based Antisense Oligomers in Tumor and Angiogen... | | |
| Hudziak RM, Weller DL, Weller DD, Barofsky E | Proceedings of the ASMS Conference on Mass Spectrometry and Allied Topics 1996 44:607 | | Mass Spectrometric Analysis of Morpholino Phosphorodiamidate Oligomers | | |
| Smith AW, Skilling DE, Matson DO, Kroeker AD, Stein DA, Berke T, Iversen PL | J Am Vet Med Assoc. 2002 Feb 15;220(4):455-8 | | Detection of vesicular exanthema of swine-like calicivirus in tissues from a naturally infected s... | not applicable | calicivirus |
| Summerton J | In: Peptide Nucleic Acids, Morpholinos, and Related Antisense Biomolecules. Janson C. and During... | | Morpholinos and PNAs Compared | | |
| Tucker RP | Acta Histochemica et Cytochemica, 2002, vol. 35, no. 5, pp. 361-366 | | Using Antisense Morpholino Oligos to Knockdown Gene Expression in the Chicken Embryo | | chick embryo |
| Okamoto H, Hirate Y, Ando H | Frontiers in Bioscience. 2004 Jan 1;9:93-9 | | Systematic Identification of Factors in Zebrafish Regulating the Early Midbrain and Cerebellar De... | | zebrafish |
| Ge Q, Stein D, Kroeker A, Iversen P, Chen J | Program and abstracts of the 44th Interscience Conference of Antimicrobial Agents and Chemotherap... | | Inhibition of influenza A virus production in vero cells with morpholino oligomers | | |
| Summerton J and Weller D | Nucleosides Nucleotides 1997; 16: 889-898 | | Antisense properties of morpholino oligomers | | |
| Neugebauer JM, Amack JD, Peterson AG, Bisgrove BW, Yost HJ | Nature. 2009 Feb 25. [Epub ahead of print] | | FGF signalling during embryo development regulates cilia length in diverse epithelia | | zebrafish |
| Rottbauer W, Wessels G, Dahme T, Just S, Trano N, Hassel D, Burns CG, Katus HA, Fishman MC | Circ Res. 2006 Aug 4;99(3):323-31. Epub 2006 Jun 29 |
| Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contr... | | zebrafish |
| Iversen P, Ghosh C, Stein D, Weller D | Antisense Technology, Part A, General Methods, Methods of Delivery, and RNA Studies. Phillips I,... |
| Evaluation of Antisense Mechanisms of Action | | |
| Liu G, Dou S, Pretorius PH, Liu X, Chen L, Rusckowski M, Hnatowich DJ | Q J Nucl Med Mol Imaging. 2009 Dec 15. [Epub ahead of print] |
AIM: Using the antiCEA antibody MN14, a LS174T mouse tumor model has been successfully targeted... | Tumor pretargeting in mice using MORF conjugated CC49 antibody and radiolabeled complimentary cMO... | | mice |
| Martinez-Morales JR, Rembold M, Greger K, Simpson JC, Brown KE, Quiring R, Pepperkok R, Martin-Be... | Development. 2009 Jul;136(13):2165-75 |
Although the vertebrate retina is a well-studied paradigm for organogenesis, the morphogenetic ... | ojoplano-mediated basal constriction is essential for optic cup morphogenesis | Microinjection | zebrafish |
| Fletcher S, Adams AM, Johnsen RD, Greer K, Moulton HM, Wilton SD | Mol Ther. 2010 Mar 23. [Epub ahead of print] |
Antisense oligomer-induced manipulation of dystrophin pre-mRNA processing can remove exons carr... | Dystrophin Isoform Induction In Vivo by Antisense-mediated Alternative Splicing | peptide-coupled | mice |
| Jedrusik A, Bruce AW, Tan MH, Leong DE, Skamagki M, Yao M, Zernicka-Goetz M | Dev Biol. 2010 Apr 26. [Epub ahead of print] |
Divisions of polarised blastomeres that allocate polar cells to outer and apolar cells to inner... | Maternally and zygotically provided Cdx2 have novel and critical roles for early development of t... | | Mouse embryo |
| Huang C, Gu S, Yu P, Yu F, Feng C, Gao N, Du J | Dev Biol. 2009 Dec 23. [Epub ahead of print] |
Mutations in SMARCAL1 cause Schimke Immuno-Osseous Dysplasia (SIOD), an autosomal recessive mul... | Deficiency of smarcal1 causes cell cycle arrest and developmental abnormalities in zebrafish | | zebrafish |
| Tucker RP | Dev Dyn 2001 Sep;222(1):115-9 | A key feature of vertebrate development is the formation of the neural crest. In the trunk, ne... | Abnormal neural crest cell migration after the in vivo knockdown of tenascin-C expression with mo... | Electroporation | chick embryo |
| Stalmans I, Lambrechts D, De Smet F, Jansen S, Wang J, Maity S, Kneer P, Von Der Ohe M, Swillen A... | Nat Med. 2003 Feb;9(2):173-82 | Hemizygous deletion of chromosome 22q11 (del22q11) causes thymic, parathyroid, craniofacial an... | VEGF: A modifier of the del22q11 (DiGeorge) syndrome? | Microinjection | zebrafish |
| Vendrell V, Gimnopoulos D, Becker T and Schimmang T | Int. J. Dev. Biol. 2001 45 (S1): S105-S106 | FGF3 has been involved in the development of the inner ear in a number of species including mous... | Functional analysis of FGF3 during zebrafish inner ear development. | Microinjection | zebrafish |
| Childs S, Chen JN, Garrity DM, Fishman MC | Development. 2002 Feb;129(4):973-8 | Little is known about how vascular patterns are generated in the embryo. The vasculature of the ... | Patterning of angiogenesis in the zebrafish embryo | Microinjection | zebrafish |
| Smith AW, Matson DO, Stein DA, Skilling DE, Kroeker AD, Berke T, Iversen PL | Curr Opin Mol Ther. 2002 Apr;4(2):177-84 | The Earth's oceans are the primary reservoir for an emerging family of RNA viruses, the Calicivi... | Antisense treatment of caliciviridae: an emerging disease agent of animals and humans | | |
| Devine CA, Key B | Methods in Cell Science. 2003; 25(1-2):33-37 | The method described here outlines a simple protocol to investigate the in vivo function of axon... | Identifying axon guidance defects in the embryonic zebrafish brain | Microinjection | zebrafish |
| Lewis JL, Bonner J, Modrell M, Ragland JW, Moon RT, Dorsky RI, Raible DW. | Development. 2004 Mar;131(6):1299-308. | While Wnt/beta-catenin signaling is known to be involved in the development of neural crest cell... | Reiterated Wnt signaling during zebrafish neural crest development. | Microinjection | zebrafish |
| Luo KL, Luo JH, Yu YP | Cancer Sci. 2009. [Epub ahead of print] | (-)-Epigallocatechin-3-gallate (EGCG) is one of the major polyphenol components in green tea. It ... | (-)-Epigallocatechin-3-gallate induces Du145 prostate cancer cell death via downregulation of inh... | | cell culture: human prostate cancer cell line Du145 |
| Scholpp S, Wolf O, Brand M, Lumsden A | Development. 2006 Mar;133(5):855-64. Epub 2006 Feb 1 | . . . Midway between the anterior neural border and the midbrain-hindbrain boundary, two well-k... | Hedgehog signalling from the zona limitans intrathalamica orchestrates patterning of the zebrafis... | Microinjection | zebrafish |
| Pak JH, Manevich Y, Kim HS, Feinstein SI, Fisher AB | J Biol Chem. 2002 Dec 20;277(51):49927-34. Epub 2002 Oct 07 | 1-cys peroxiredoxin (1-cysPrx), a member of the peroxiredoxin superfamily, reduces phospholipid h... | An antisense oligonucleotide to 1-cys peroxiredoxin causes lipid peroxidation and apoptosis in lu... | Special Delivery | cell culture: L2 cells |
| Hsieh DJ, Liao CF | Br J Pharmacol. 2002 Nov 6;137(6):782-792 | 1. A zebrafish M(2) muscarinic acetylcholine receptor (mAChR) gene was cloned. It encodes 495 ami... | Zebrafish M(2) muscarinic acetylcholine receptor: cloning, pharmacological characterization, expr... | Microinjection | zebrafish |
| Teraoka H, Ogawa A, Kubota A, Stegeman JJ, Peterson RE, Hiraga T | Aquat Toxicol. 2010 May 7. [Epub ahead of print] | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) causes various signs of toxicity in early life stages ... | Malformation of certain brain blood vessels caused by TCDD activation of Ahr2/Arnt1 signaling in ... | | zebrafish |
| Dong W, Teraoka H, Tsujimoto Y, Stegeman JJ, Hiraga T | Toxicol Sci. 2004 Jan;77(1):109-16. Epub 2003 Dec 03 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent and potent developmental toxicant in v... | Role of Aryl Hydrocarbon Receptor in Mesencephalic Circulation Failure and Apoptosis in Zebrafish... | Microinjection | zebrafish |
| Tadjuidje E, Hollemann T. | Dev Dyn. 2006 Aug;235(8):2095-110.Click here to read | 7-dehydrocholesterol reductase (7-Dhcr) catalyses the final step in the pathway of cholesterol bi... | Cholesterol homeostasis in development: the role of Xenopus 7-dehydrocholesterol reductase (Xdhcr... | Microinjection | Xenopus laevis |
| Giles RV, Spiller DG, Clark RE, Tidd DM | Antisense Nucleic Acid Drug Dev 1999 Apr;9(2):213-20 | A 28-mer morpholino oligonucleotide analog was designed to hybridize to 8 bases of intron 1 and e... | Antisense morpholino oligonucleotide analog induces missplicing of c-myc mRNA | streptolysin O | cell culture: human leukemia lines |
| Lee HS, Nishanian TG, Mood K, Bong YS, Daar IO | Nat Cell Biol. 2008 Aug;10(8):979-86. Epub 2008 Jul 6 | A body of evidence is emerging that shows a requirement for ephrin ligands in the proper migratio... | EphrinB1 controls cell-cell junctions through the Par polarity complex | Microinjection | Xenopus |
| Ochi H, Hans S, Westerfield M | J Biol Chem. 2008 Feb 8;283(6):3529-36. Epub 2007 Dec 3. | A cascade of signaling events triggers myogenesis in vertebrates. Although studies of zebrafish i... | Smarcd3 regulates the timing of zebrafish myogenesis onset | | zebrafish |
| Gore AV, Maegawa S, Cheong A, Gilligan PC, Weinberg ES, Sampath K | Nature. 2005 Dec 15;438(7070):1030-5 | A central question in the development of multicellular organisms pertains to the timing and mecha... | The zebrafish dorsal axis is apparent at the four-cell stage | Microinjection | zebrafish |
| Hill AJ, Bello SM, Prasch AL, Peterson RE, Heideman W | Toxicol Sci. 2004 Mar;78(1):78-87. Epub 2004 Jan 12 | A common response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in teleost embryos is bl... | Water permeability and TCDD-induced edema in zebrafish early-life stages | Microinjection | zebrafish |
| Hämmerle B, Tejedor FJ | PLoS ONE. 2007 Nov 14;2(11):e1169 | A complete account of the whole developmental process of neurogenesis involves understanding a nu... | A Novel Function of DELTA-NOTCH Signalling Mediates the Transition from Proliferation to Neurogen... | Electroporation | chick embryo |
| Woo AJ, Moran TB, Schindler Y, Choe SK, Langer NB, Sullivan MR, Fujiwara Y, Paw BH, Cantor AB | Mol Cell Biol. 2008 Apr;28(8):2675-89. Epub 2008 Feb 4. | A complete understanding of the transcriptional regulation of developmental lineages requires tha... | Identification of ZBP-89 as a Novel GATA-1 Associated Transcription Factor Involved in Megakaryoc... | | zebrafish |
| Nichane M, Ren X, Bellefroid EJ | EMBO J. 2010 Jan 6;29(1):55-67. Epub 2009 Oct 22 | A complex set of extracellular signals is required for neural crest (NC) specification. However, ... | Self-regulation of Stat3 activity coordinates cell-cycle progression and neural crest specificati... | Microinjection | Xenopus |
| Miller CT, Yelon D, Stainier DY, Kimmel CB | Development. 2003 Apr;130(7):1353-65 | A conserved endothelin 1 signaling pathway patterns the jaw and other pharyngeal skeletal element... | Two endothelin 1 effectors, hand2 and bapx1, pattern ventral pharyngeal cartilage and the jaw joi... | Microinjection | zebrafish |
| Shu X, Huang J, Dong Y, Choi J, Langenbacher A, Chen JN | Development. 2007 May;134(10):1921-30. Epub 2007 Apr 18 | A conserved molecular cascade involving Nodal signaling that patterns the laterality of the later... | Na,K-ATPase alpha2 and Ncx4a regulate zebrafish left-right patterning | | zebrafish |
| Sinner D, Kirilenko P, Rankin S, Wei E, Howard L, Kofron M, Heasman J, Woodland HR, Zorn AM | Development. 2006 May;133(10):1955-66. | A conserved molecular pathway has emerged controlling endoderm formation in Xenopus zebrafish and... | Global analysis of the transcriptional network controlling Xenopus endoderm formation | Microinjection | Xenopus |
| Massé K, Bhamra S, Eason R, Dale N, Jones EA | Nature. 2007 Oct 25;449(7165):1058-62 | A conserved network of eye field transcription factors (EFTFs) underlies the development of the e... | Purine-mediated signalling triggers eye development | | Xenopus laevis |
| Zhou L, Civitello ER, Gupta N, Silverman RH, Molinaro RJ, Anderson DE, Torrence PF | Bioconjug Chem. 2005 Mar 16;16(2):383-390 | A convergent synthetic approach was used to conjugate 2',5'-oligoadenylate (2-5A, p5'A2' [p5'A2']... | Endowing RNase H-Inactive Antisense with Catalytic Activity: 2-5A-Morphants. | not applicable | not applicable |
| Pfaff KL, Straub CT, Chiang K, Bear DM, Zhou Y, Zon LI | Mol Cell Biol. 2007 Aug;27(16):5887-97. Epub 2007 Jun 18. | A critical step in cell division is formation of the mitotic spindle, which is a bipolar array of... | The zebrafish cassiopeia mutant reveals that SIL is required for mitotic spindle organization | | zebrafish |
| Dees E, Robertson JB, Ashe M, Pabon-Pena LM, Bader D, Goodwin RL | Anat Rec A Discov Mol Cell Evol Biol. 2005 Sep;286A(1):823-32. | A defining characteristic of embryonic cells is their ability to divide rapidly, even in tissues ... | LEK1 protein expression in normal and dysregulated cardiomyocyte mitosis | Special Delivery | cell culture: mouse neonatal cardiac myocytes |
| Osada S, Ohmori SY, Taira M. | Development 2003 May;130(9):1783-94 | A family of inner nuclear membrane proteins is implicated in gene regulation by interacting with ... | XMAN1, an inner nuclear membrane protein, antagonizes BMP signaling by interacting with Smad1 in ... | Microinjection | Xenopus |
| Schuff M, Rossner A, Wacker SA, Donow C, Gessert S, Knochel W. | Dev Dyn. 2007 Jan;236(1):226-39. | A functional knockdown of FoxN3, a member of subclass N of fork head/winged helix transcription f... | FoxN3 is required for craniofacial and eye development of Xenopus laevis. | Microinjection | Xenopus laevis |
| Piloto S, Schilling TF | Development. 2010 Jun;137(12):1981-90. Epub 2010 May 12. Erratum in: Development. 2010 Aug 1;137(... | A fundamental issue in cell biology is how migratory cell behaviors are controlled by dynamically... | Ovo1 links Wnt signaling with N-cadherin localization during neural crest migration | | zebrafish |
