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Morpholino Publications Database

Publications - Page 3
AuthorsCitationAbstractTitleDelivery MethodOrganism
An M, Henion PDInt J Dev Biol. 2012;56:223-37 doi: 10.1387/ijdb.113383maThe functions of gene regulatory networks that control embryonic cell diversification occur on a ...The zebrafish sf3b1b460 mutant reveals differential requirements for the sf3b1 pre-mRNA processin...Microinjectionzebrafish
Anant S, Henderson JO, Mukhopadhyay D, Navaratnam N, Kennedy S, Min J, Davidson NOJ Biol Chem. 2001 Dec 14;276(50):47338-51. Epub 2001 Sep 27Mammalian apolipoprotein B (apoB) mRNA editing is mediated by a multicomponent holoenzyme contain...Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editi...Special Deliverycell culture: rat hepatoma, McArdle7777
Anantpadma M, Stein DA, Vrati SJ Antimicrob Chemother. 2010 Mar 18. [Epub ahead of print]Background Japanese encephalitis virus (JEV) has a significant impact on public health throughout...Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-con...peptide-coupledmice and cell culture: Vero, Neuro2A and J774E cells
Anas MK, Lee MB, Zhou C, Hammer MA, Slow S, Karmouch J, Liu XJ, Bröer S, Lever M, Baltz JMDevelopment. 2008 Dec;135(24):4123-30Betaine (N,N,N-trimethylglycine) added to culture media is known to substantially improve the dev...SIT1 is a betaine/proline transporter that is activated in mouse eggs after fertilization and fun...
Anastasaki C, Longman D, Capper A, Patton EE, Cáceres JFNucleic Acids Res. 2011 Jan 11. [Epub ahead of print]The nonsense-mediated mRNA decay (NMD) pathway is a highly conserved surveillance mechanism that ...Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafis...zebrafish
Andermann P, Ungos J, Raible DWDev Biol. 2002 Nov 1;251(1):45-58Cells delaminate from epithelial placodes to form sensory ganglia in the vertebrate head. We desc...Neurogenin1 Defines Zebrafish Cranial Sensory Ganglia PrecursorsMicroinjectionzebrafish
Anderson JL, Carten JD, Farber SAMethods Cell Biol. 2011;101:111-41. doi: 10.1016/B978-0-12-387036-0.00005-0. ReviewLipids serve essential functions in cells as signaling molecules, membrane components, and source...Zebrafish lipid metabolism: from mediating early patterning to the metabolism of dietary fat and ...Microinjectionzebrafish
Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Lori Sussel LDevelopment. 2011;138:3213-3224; doi:10.1242/dev.058693The homeodomain transcription factor Nkx2.2 is essential for pancreatic development and islet cel...The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell m...Microinjectionzebrafish
Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel LJ Biol Chem. 2009 Sep 15. [Epub ahead of print]Nkx2.2 and NeuroD1 are two critical regulators of pancreatic beta cell development. Nkx2.2 is a h...Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) BY ...zebrafish
Anderson MJ, Pham VN, Vogel AM, Weinstein BM, Roman BLDev Biol. 2008 Jun 15;318(2):258-67. Epub 2008 Mar 26Aortic arch malformations are common congenital disorders that are frequently of unknown etiology...Loss of unc45a precipitates arteriovenous shunting in the aortic archesMicroinjectionzebrafish
Anderson RM, Bosch JA, Goll MG, Hesselson D, Dong PD, Shin D, Chi NC, Shin CH, Schlegel A, Halper...Dev Biol. 2009 Jul 21. [Epub ahead of print]Developmental mechanisms regulating gene expression and the stable acquisition of cell fate direc...Loss of Dnmt1 catalytic activity reveals multiple roles for DNA methylation during pancreas devel...zebrafish
Andersson O, Adams BA, Yoo D, Ellis GC, Gut P, Anderson RM, German MS, Stainier DYCell Metab. 2012 Jun 6;15(6):885-94. Epub 2012 May 17Diabetes can be controlled with insulin injections, but a curative approach that restores the num...Adenosine signaling promotes regeneration of pancreatic β cells in vivoMicroinjectionzebrafish
Ando H, Kobayashi M, Tsubokawa T, Uyemura K, Furuta T, Okamoto HDev Biol. 2005 Nov 15;287(2):456-68. Epub 2005 Oct 14.The telencephalon shows the greatest degree of size variation in the vertebrate brain. Understand...Lhx2 mediates the activity of Six3 in zebrafish forebrain growthMicroinjectionzebrafish
Ando H, Okamoto HMar Biotechnol (NY). 2006 May-Jun;8(3):295-303. Epub 2006 Apr 18Functional analyses of gene function by knockdown and expression approaches strongly enhance the ...Efficient Transfection Strategy for the Spatiotemporal Control of Gene Expression in ZebrafishLipofectinzebrafish
Andoniadou CL, Signore M, Young RM, Gaston-Massuet C, Wilson SW, Fuchs E, Martinez-Barbera JPDevelopment. 2011 Oct 17. [Epub ahead of print]The Wnt/β-catenin pathway plays an essential role during regionalisation of the vertebrate neural...HESX1- and TCF3-mediated repression of Wnt/beta-catenin targets is required for normal developmen...Microinjectionzebrafish
Andreazzoli M, Gestri G, Cremisi F, Casarosa S, Dawid IB, Barsacchi G.Development. 2003 Nov;130(21):5143-54.In Xenopus neuroectoderm, posterior cells start differentiating at the end of gastrulation, while...Xrx1 controls proliferation and neurogenesis in Xenopus anterior neural plate.MicroinjectionXenopus
Angeles Julaton VT, Reijo Pera AHum Mol Genet. 2011 Mar 19. [Epub ahead of print]Human infertility is common and frequently linked to poor germ cell development. Yet, human germ ...NANOS3 function in human germ cell developmentElectroporation (Amaxa)Cell culture: human embryonic stem cells (hESC) H9 (XX)
Angerer LM, Angerer RCMethods Cell Biol. 2004;74:699-711No abstract available. Disruption of gene function using antisense morpholinos.
Angerer LM, Newman LA, Angerer RCDevelopment. 2005 Mar;132(5):999-1008. Epub 2005 Feb 2Patterning of cell fates along the sea urchin animal-vegetal embryonic axis requires the opposing...SoxB1 downregulation in vegetal lineages of sea urchin embryos is achieved by both transcriptiona...MicroinjectionSea urchin, Strongylocentrotus purpuratus
Angerer LM, Oleksyn DW, Levine AM, Li X, Klein WH, Angerer RCDevelopment. 2001 Nov;128(22):4393-404We have identified a single homolog of goosecoid, SpGsc, that regulates cell fates along both the...Sea urchin goosecoid function links fate specification along the animal-vegetal and oral-aboral e...Microinjectionsea urchin
Angotzi AR, Mungpakdee S, Stefansson S, Male R, Chourrout DGen Comp Endocrinol. 2011 Feb 26. [Epub ahead of print]When mutated in mammals, paired-like homeobox Prop1 gene produces highly variable pituitary pheno...Involvement of Prop1 homeobox gene in the early development of fish pituitary glandzebrafish
Anichtchik O, Diekmann H, Fleming A, Roach A, Goldsmith P, Rubinsztein DCJ Neurosci. 2008 Aug 13;28(33):8199-207Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder in the Western w...Loss of PINK1 function affects development and results in neurodegeneration in zebrafishzebrafish
AnonymousThe illustrious websiteTesting, 1...2...3 *pFFFFt*Can this be cancelled?
Anquetil V, Le Sommer C, Méreau A, Hamon S, Lerivray H, Hardy SJ Biol Chem. 2009 Sep 17. [Epub ahead of print]Alternative splicing of 3' terminal exons plays a critical role in gene expression by producing m...The polypyrimidine tract binding protein (PTB) prevents the activity of an intronic regulatory el...Xenopus
Anthony K, Feng L, Arechavala-Gomeza V, Guglieri M, Straub V, Bushby K, Cirak S, Morgan J, Munton...Hum Gene Ther Methods. 2012 Oct 17. [Epub ahead of print]Restoration of the open reading frame of the DMD gene and dystrophin protein production in Duchen...Exon Skipping Quantification by qRT-PCR in Duchenne Muscular Dystrophy Patients Treated with the ...i.v. infusionhuman
Antic D, Stubbs JL, Suyama K, Kintner C, Scott MP, Axelrod JDPLoS One. 2010 Feb 2;5(2):e8999Left-right asymmetry in vertebrates is initiated in an early embryonic structure called the ventr...Planar Cell Polarity Enables Posterior Localization of Nodal Cilia and Left-Right Axis Determinat...MicroinjectionXenopus laevis
Antkiewicz DS, Peterson RE, Heideman WToxicol Sci. 2006 Nov;94(1):175-82. Epub 2006 Aug 25.The zebrafish (Danio rerio) has become an attractive vertebrate model for studying developmental ...Blocking Expression of AHR2 and ARNT1 in Zebrafish Larvae Protects Against Cardiac Toxicity of 2,...Microinjectionzebrafish
Anzenberger U, Bit-Avragim N, Rohr S, Rudolph F, Dehmel B, Willnow TE, Abdelilah-Seyfried SJ Cell Sci. 2006 May 15;119(Pt 10):2127-37. Epub 2006 Apr 25Megalin/LRP2 is an endocytic receptor in the proximal tubules of the mammalian kidney that plays ...Elucidation of megalin/LRP2-dependent endocytic transport processes in the larval zebrafish prone...Microinjectionzebrafish
Aoki Y, Nakamura A, Yokota T, Saito T, Okazawa H, Nagata T, Takeda SMol Ther. 2010 Sep 7. [Epub ahead of print]A promising therapeutic approach for Duchenne muscular dystrophy (DMD) is exon skipping using ant...In-frame Dystrophin Following Exon 51-Skipping Improves Muscle Pathology and Function in the Exon...Injectionmice, mdx
Aoki Y, Saint-Germain N, Gyda M, Magner-Fink E, Lee YH, Credidio C, Saint-Jeannet JPDev Biol. 2003 Jul 1;259(1):19-33The transcription factors of the Sox family play important roles in diverse developmental process...Sox10 regulates the development of neural crest-derived melanocytes in Xenopus.MicroinjectionXenopus
Aoki Y, Yokota T, Nagata T, Nakamura A, Tanihata J, Saito T, Duguez SMR, Nagaraju K, Hoffman EP, ...PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1204638109Duchenne muscular dystrophy (DMD), the commonest form of muscular dystrophy, is caused by lack of...Bodywide skipping of exons 45–55 in dystrophic mdx52 mice by systemic antisense deliveryVivo-Morpholinomice, mdx52
Aoyama K, Burns DM, Suh SW, Garnier P, Matsumori Y, Shiina H, Swanson RAJ Cereb Blood Flow Metab. 2005 Mar;25(3):358-70.Endoplasmic reticulum (ER) stress leads to activation of caspase-12, which in turn can lead to ac...Acidosis causes endoplasmic reticulum stress and caspase-12-mediated astrocyte deathSpecial Deliverycell culture: mouse astrocytes
Appel B, Marasco P, McClung LE, Latimer AJDev Dyn. 2003 Oct;228(2):281-6Cells that occupy the midline of vertebrate embryos arise from a common population of precursors....lunatic fringe regulates Delta-Notch induction of hypochord in zebrafishzebrafish
Appelbaum L, Anzulovich A, Baler R, Gothilf YJ Biol Chem. 2005 Mar 25;280(12):11544-51. Epub 2005 Jan 18In non-mammalian vertebrates, the pineal gland is photoreceptive and contains an intrinsic circad...Homeobox-clock protein interaction in zebrafish: A shared mechanism for pineal-specific and circa...Microinjectionzebrafish
Aquilina-Beck A, Ilagan K, Liu Q, Liang JOBMC Dev Biol. 2007 Nov 8;7(1):126 [Epub ahead of print] ABSTRACT: BACKGROUND: Nodals are secreted signaling proteins with many roles in vertebrate develo...Nodal signaling is required for closure of the anterior neural tube in zebrafishzebrafish
Araki I, Brand MGenesis. 2001 Jul;30(3):157-9No abstract availableMorpholino-induced knockdown of Fgf8 efficiently phenocopies the acerebellar (ACE) phenotypeMicroinjectionzebrafish
Araki T, Kusakabe M, Nishida EJ Biol Chem. 2010 Dec 21. [Epub ahead of print]Epidermal differentiation in the ventral ectoderm of Xenopus embryos is regulated by the bone mor...A transmembrane protein EIG121L is required for epidermal differentiation during early embryonic ...Xenopus
Archer A, Srinivas Kitambi S, Hallgren SL, Pedrelli M, Håkan Olsén K, Mode A, Gustafsson JOpen J Endocrine Metabolic Dis. 2012;2(4):74-81. doi: 10.4236/ojemd.2012.24012The liver X-receptors (LXRs) act as cholesterol sensors and participate in the regulation of lipi...The Liver X-Receptor (Lxr) Governs Lipid Homeostasis in Zebrafish during DevelopmentMicroinjectionzebrafish
Archer TC, Jin J, Casey ESDev Biol. 2011 Feb 15;350(2):429-40. Epub 2010 Dec 11Sox1, Sox2 and Sox3, the three members of the SoxB1 subgroup of transcription factors, have simil...Interaction of Sox1, Sox2, Sox3 and Oct4 during primary neurogenesisMicroinjectionXenopus laevis
Arduini BL, Bosse KM, Henion PDDevelopment. 2009 Jun;136(12):1987-94. Epub 2009 May 13The neural crest generates multiple cell types during embryogenesis but the mechanisms regulating...Genetic ablation of neural crest cell diversificationzebrafish
Arenas-Mena C, Cameron RA, Davidson EHDev Growth Differ. 2006 Sep;48(7):463-72Sphox11/13b is one of the two hox genes of Strongylocentrotus purpuratus expressed in the embryo....Hindgut specification and cell-adhesion functions of Sphox11/13b in the endoderm of the sea urchi...MicroinjectionSea urchin, Strongylocentrotus purpuratus
Argasinska J, Rana AA, Gilchrist MJ, Lachani K, Young A, Smith JCInt J Dev Biol. 2009;53(1):37-43Members of the REEP (Receptor expression enhancing protein) family contain a TB2/DP1, HVA22 domai...Loss of REEP4 causes paralysis of the Xenopus embryoXenopus tropicalis
Argenton F, Giudici S, Deflorian G, Cimbro S, Cotelli F, Beltrame MMech Dev. 2004 Feb;121(2):131-42Sox proteins are DNA-binding proteins belonging to the HMG box superfamily and they play key role...Ectopic expression and knockdown of a zebrafish sox21 reveal its role as a transcriptional repres...Microinjectionzebrafish
Arkhipova V, Wendik B, Devos N, Ek O, Peers B, Meyer DDev Biol. 2012 May 1;365(1):290-302. Epub 2012 Mar 9Differentiation of insulin producing beta-cells is a genetically well defined process that involv...Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafi...Microinjectionzebrafish
Armas P, Margarit E, Mouguelar VS, Allende ML, Calcaterra NBPLoS ONE. 2013;8(5):e63234. doi:10.1371/journal.pone.0063234CNBP is a nucleic acid chaperone implicated in vertebrate craniofacial development, as well as in...Beyond the Binding Site: In Vivo Identification of tbx2, smarca5 and wnt5b as Molecular Targets o...Microinjectionzebrafish
Armisen R, Fuentes R, Olguin P, Cabrejos ME, Kukuljan MJ Neurosci. 2002 Oct 1;22(19):8347-51The ability of neurons to fire rapid action potential relies on the expression of voltage-gated s...Repressor element-1 silencing transcription/neuron-restrictive silencer factor is required for ne...MicroinjectionXenopus laevis
Armisen R, Fuentes R, Olguin P, Cabrejos ME, Kukuljan M.J Neurosci. 2002 Oct 1;22(19):8347-51.The ability of neurons to fire rapid action potential relies on the expression of voltage-gated s...Repressor element-1 silencing transcription/neuron-restrictive silencer factor is required for ne...MicroinjectionXenopus laevis
Arnaud E, Ferri KF, Thibaut J, Haftek-Terreau Z, Aouacheria A, Le Guellec D, Lorca T, Gillet GCell Death Differ. 2006 Jul;13(7):1128-37. Epub 2005 Nov 11.Although the role of the b-cell lymphoma (Bcl)-2 family of apoptosis inhibitors is well documente...The zebrafish bcl-2 homologue Nrz controls development during somitogenesis and gastrulation via ...Microinjectionzebrafish
Arniges M, Vazquez E, Fernandez-Fernandez JM, Valverde MAJ Biol Chem. 2004 Dec 24;279(52):54062-8. Epub 2004 Oct 15The vertebrate transient receptor potential cationic channel TRPV4 has been proposed as an osmo- ...Swelling-activated Ca2+ entry via TRPV4 channel is defective in cystic fibrosis airway epitheliatransfectioncell culture: CFT1 cells
Arora VMethods Mol Med. 2004;106:273-92The concept of metabolic redirection involves shifting the metabolism of a substrate away from on...Antisense strategies for redirection of drug metabolism: using Paclitaxel as a modelrats, Sprague Dawley

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