Publications - Page 1
| Authors | Citation | Abstract | Title | Delivery Method | Organism |
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| Esaki M, Hoshijima K, Kobayashi S, Fukuda H, Kawakami K, Hirose S | Am J Physiol Regul Integr Comp Physiol. 2007 Jan;292(1):R470-80. Epub 2006 Aug 31. | Uptake of Na(+) from the environment is an indispensable strategy for the survival of freshwater ... | Visualization in zebrafish larvae of Na+ uptake in mitochondrion-rich cells whose differentiation... | Microinjection | zebrafish |
| Zhang YJ, Wang KY, Stein DA, Patel D, Watkins R, Moulton HM, Iversen PL, Matson DO | Antiviral Res. 2007 Jan;73(1):12-23. Epub 2006 Jun 14. | Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with Kaposi's sarcoma and primary ef... | Inhibition of replication and transcription activator and latency-associated nuclear antigen of K... | peptide-coupled | cell culture: PEL cells |
| Cheng L, Guo XF, Yang XY, Chong M, Cheng J, Li G, Gui YH, Lu DR | Biochem Biophys Res Commun. 2006 Jun 16;344(4):1290-9. Epub 2006 Apr 19. | delta-sarcoglycan, one member of the sarcoglycan complex, is a very conservative muscle-specific ... | delta-sarcoglycan is necessary for early heart and muscle development in zebrafish | Microinjection | zebrafish |
| Chiou MJ, Chao TT, Wu JL, Kuo CM, Chen JY | Biochem Biophys Res Commun. 2006 Oct 20;349(2):750-8. Epub 2006 Aug 28. | During mouse embryogenesis, CTGF/CCN2 is expressed in zones containing hypertrophic chondroctyes ... | The physiological role of CTGF/CCN2 in zebrafish notochond development and biological analysis of... | Microinjection | zebrafish |
| Weber GJ, Choe SE, Dooley KA, Paffett-Lugassy NN, Zhou Y, Zon LI. | Blood. 2005 Jul 15;106(2):521-30. Epub 2005 Apr 12. | Hematopoiesis involves the production of stem cells, followed by the orchestrated differentiation... | Mutant specific gene programs in the zebrafish | Microinjection | zebrafish |
| Nissen RM, Amsterdam A, Hopkins N | BMC Dev Biol. 2006 Jun 7;6:28. | ABSTRACT: BACKGROUND: Craniofacial birth defects result from defects in cranial neural crest (NC)... | A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required ... | Microinjection | zebrafish |
| Isenberg, J. S., Romeo, M. J., Abu-Asab, M., Tsokos, M., Oldenborg, A., Pappan, L., Wink, D. A. ... | Circ. Res. 100:712-720, 2007 | Thrombospondin-1 (TSP1) limits the angiogenic and vasodilator activities of NO. This activity of ... | Increasing survival of ischemic tissue by targeting CD47. | in vivo: injection | mice and cell culture |
| Saulnier DM, Ghanbari H, Brandli AW | Dev Biol. 2002 Aug 1;248(1):13-28 | In the vertebrate embryo, development of the excretory system is characterized by the successive ... | Essential function of wnt-4 for tubulogenesis in the Xenopus pronephric kidney | Microinjection | Xenopus |
| Cheng W, Guo L, Zhang Z, Soo HM, Wen C, Wu W, Peng J | Dev Biol. 2006 Jun 15;294(2):482-96. Epub 2006 Apr 24. | Defects in some of liver-enriched genes in mammals will cause liver- and/or blood-related disease... | HNF factors form a network to regulate liver-enriched genes in zebrafish | Microinjection | zebrafish |
| van der Meer DL, Marques IJ, Leito JT, Besser J, Bakkers J, Schoonheere E, Bagowski CP | Dev Biol. 2006 Nov 15;299(2):356-72. Epub 2006 Aug 4. | Mammalian CYPHER (Oracle, KIA0613), a member of the PDZ-LIM family of proteins (Enigma/LMP-1, ENH... | Zebrafish cypher is important for somite formation and heart development | Microinjection | zebrafish |
| Sato M, Tsai HJ, Yost HJ | Dev Biol. 2006 Oct 1;298(1):12-21. Epub 2006 Jun 2. | The primary heart field in all vertebrates is thought to be derived exclusively from lateral plat... | Semaphorin3D regulates invasion of cardiac neural crest cells into the primary heart field | Microinjection | zebrafish |
| Feng L, Hernandez RE, Waxman JS, Yelon D, Moens CB | Dev Biol. 2009 Oct 26. [Epub ahead of print] | Retinoic acid (RA) is an important developmental signaling molecule responsible for the patternin... | Dhrs3a Regulates Retinoic Acid Biosynthesis through a Feedback Inhibition Mechanism | | zebrafish |
| Brott BK, Sokol SY. | Dev Cell. 2005 May;8(5):703-15. | Early stages of vertebrate heart development have been linked to Wnt signaling. Here we show in b... | A vertebrate homolog of the cell cycle regulator Dbf4 is an inhibitor of Wnt signaling required f... | Microinjection | Xenopus |
| Liu F, van den Broek O, Destree O, Hoppler S | Development. 2005 Dec;132(24):5375-85. Epub 2005 Nov 16. | Tcf/Lef transcription factors and beta-catenin mediate canonical Wnt signalling, which plays rema... | Distinct roles for Xenopus Tcf/Lef genes in mediating specific responses to Wnt/beta-catenin sign... | Microinjection | Xenopus laevis |
| Honjo Y, Eisen JS | Development. 2005 Oct;132(20):4461-70. Epub 2005 Sep 14. | In avians and mice, trunk neural crest migration is restricted to the anterior half of each somit... | Slow muscle regulates the pattern of trunk neural crest migration in zebrafish | Microinjection | zebrafish |
| Fairbank PD, Lee C, Ellis A, Hildebrand JD, Gross JM, Wallingford JB | Development. 2006 Oct;133(20):4109-18. Epub 2006 Sep 20. | Shroom family proteins have been implicated in the control of the actin cytoskeleton, but so far ... | Shroom2 (APXL) regulates melanosome biogenesis and localization in the retinal pigment epithelium | Microinjection | Xenopus tropicalis |
| Moreno M, Munoz R, Aroca F, Labarca M, Brandan E, Larrain J | EMBO J. 2005 Apr 6;24(7):1397-405. Epub 2005 Mar 17. | The BMP4 signaling pathway plays key roles during early embryonic development and for maintenance... | Biglycan is a new extracellular component of the Chordin-BMP4 signaling pathway. | Microinjection | Xenopus |
| Yamamoto T, Suzuki N | J Biol Chem. 2005 Apr 29;280(17):16979-86. Epub 2005 Feb 14. | We isolated and characterized cDNA clones (PKG Ia and PKG Ib) for medaka fish cGMP-dependent prot... | Expression and function of cGMP-dependent protein kinase type I during medaka fish embryogenesis | Microinjection | medaka |
| Dumont J, Umbhauer M, Rassinier P, Hanauer A, Verlhac MH | J Cell Biol. 2005 Apr 25;169(2):227-31. Epub 2005 Apr 18. | Vertebrate oocytes arrest in metaphase of the second meiotic division (MII), where they maintain ... | p90Rsk is not involved in cytostatic factor arrest in mouse oocytes | Microinjection | Xenopus |
| Connor RM, Allen CL, Devine CA, Claxton C, Key B | J Comp Neurol. 2005 Apr 25;485(1):32-42 | The early axon scaffolding in the embryonic vertebrate brain consists of a series of ventrally pr... | BOC, brother of CDO, is a dorsoventral axon-guidance molecule in the embryonic vertebrate brain | Microinjection | zebrafish |
| Blasiole B, Kabbani N, Boehmler W, Thisse B, Thisse C, Canfield V, Levenson R | J Neurobiol. 2005 Sep 5;64(3):285-97. | We have analyzed the functional role of neuronal calcium sensor-1 (Ncs-1) in zebrafish developmen... | Neuronal calcium sensor-1 gene ncs-1a is essential for semicircular canal formation in zebrafish ... | Microinjection | zebrafish |
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Cui WW, Low SE, Hirata H, Saint-Amant L, Geisler R, Hume RI, Kuwada JY. | J Neurosci. 2005 Jul 13;25(28):6610-20. | shocked (sho) is a zebrafish mutation that causes motor deficits attributable to CNS defects duri... | The zebrafish shocked gene encodes a glycine transporter and is essential for the function of ear... | Microinjection | zebrafish |
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Nakamura H, Katahira T, Sato T, Watanabe Y, Funahashi J. | Mech Dev. 2004 Sep;121(9):1137-43. | It remained very difficult to manipulate gene expression in chick embryos until the advent of in ... | Gain- and loss-of-function in chick embryos by electroporation. | Electroporation | chick embryo |
| Ku M, Sokol SY, Wu J, Tussie-Luna MI, Roy AL, Hata A. | Mol Cell Biol. 2005 Aug;25(16):7144-57. | Goosecoid (Gsc) is a homeodomain-containing transcription factor present in a wide variety of ver... | Positive and negative regulation of the transforming growth factor beta/activin target gene goose... | Microinjection | Xenopus laevis |
| Hsu HJ, Hsu NC, Hu MC, Chung BC | Mol Cell Endocrinol. 2006 Mar 27;248(1-2):160-3. Epub 2005 Dec 13. Review. | Steroid hormones regulate physiological homeostasis for salt, sugar, and sex differentiation. All... | Steroidogenesis in zebrafish and mouse models | Microinjection | zebrafish |
| Zhao Y, Yang Z, Phelan JK, Wheeler DA, Lin S, McCabe ER | Mol. Endocrinol., Nov 2006; 20: 2630 - 2640. | Mutations in the human nuclear receptor, DAX1, cause X-linked adrenal hypoplasia congenita (AHC).... | Zebrafish dax1 is required for development of the interrenal organ, the adrenal cortex equivalent | Microinjection | zebrafish |
| Boyadjiev SA, Fromme JC, Ben J, Chong SS, Nauta C, Hur DJ, Zhang G, Hamamoto S, Schekman R, Ravaz... | Nat Genet. 2006 Oct;38(10):1192-7. Epub 2006 Sep 17. | Cranio-lenticulo-sutural dysplasia (CLSD) is an autosomal recessive syndrome characterized by lat... | Cranio-lenticulo-sutural dysplasia is caused by a SEC23A mutation leading to abnormal endoplasmic... | Microinjection | zebrafish |
| Valente EM, Logan CV, Mougou-Zerelli S, Lee JH, Silhavy JL, Brancati F, Iannicelli M, Travaglini ... | Nat Genet. 2010 May 30 [Epub ahead of print] | Joubert syndrome (JBTS), related disorders (JSRDs) and Meckel syndrome (MKS) are ciliopathies. We... | Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes | | zebrafish |
| Zhong TP, Childs S, Leu JP, Fishman MC | Nature 2001 Nov 8;414(6860:216-20 | Arteries and veins are morphologically, functionally and molecularly very different, but how this... | Gridlock signalling pathway fashions the first embryonic artery | Microinjection | zebrafish |
| Zhu Y, Rice CD, Pang Y, Pace M, Thomas P | Proc Natl Acad Sci U S A 2003 Mar 4;100(5):2231-6 | The structures of membrane receptors mediating rapid, nongenomic actions of steroids have not bee... | Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an ... | Microinjection | zebrafish |
| Moeller H, Jenny A, Schaeffer HJ, Schwarz-Romond T, Mlodzik M, Hammerschmidt M, Birchmeier W. | Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15900-5. Epub 2006 Oct 10. | Canonical and noncanonical Wnt signaling regulate crucial events in the development of vertebrate... | Diversin regulates heart formation and gastrulation movements in development. | Microinjection | zebrafish |
| Yamamoto T, Yao Y, Harumi T, Suzuki N | Zoolog Sci 2003;20(2):181-91 | To better understand the nitric oxide (NO) / cyclic GMP (cGMP) signaling pathway during embryogen... | Localization of the Nitric Oxide/cGMP Signaling Pathway-Related Genes and Influences of Morpholin... | Microinjection | medaka embryos |
| Prasch AL, Tanguay RL, Mehta V, Heideman W, Peterson RE | 2006 Mar;69(3):776-87. Epub 2005 Nov 23. | In order to use the zebrafish as a model to study 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) deve... | Identification of zebrafish ARNT1 homologs: TCDD toxicity in the developing zebrafish requires AR... | Microinjection | zebrafish |
| Satoh K, Ohnishi J, Sato A, Takeyama M, Iemura SI, Natsume T, Shibuya H | 2007 Nov;27(21):7623-30. Epub 2007 Sep 4 | Development of anterior neural structure in Xenopus requires the inhibition of BMP and Wnt signal... | Nemo-like kinase-myocyte enhancer factor 2A signaling regulates anterior formation in Xenopus dev... | | Xenopus |
| Nikitina N, Bronner-Fraser M, Sauka-Spengler T | 2009. Cold Spring Harb. Protoc. | Lampreys are one of the most basal animals in which many of the true vertebrate characteristics (... | Microinjection of RNA and Morpholino Oligos into Lamprey Embryos | Microinjection | Lamprey |
| Wang X, Smirnov S | ACS Nano. 2009 Mar 13. [Epub ahead of print] | The surface charge effect in controlling ionic conductance through a nanoporous alumina membrane ... | Label-Free DNA Sensor Based on Surface Charge Modulated Ionic Conductance | | |
| Sun C, Xu M, Xing Z, Wu Z, Li Y, Li T, Zhao M | Acta Biochim Biophys Sin (Shanghai). 2009 Aug;41(8):677-88 | Lissencephaly is a severe disease characterized by brain malformation. The main causative gene of... | Expression and function on embryonic development of lissencephaly-1 genes in zebrafish | | zebrafish |
| Kole R, Williams T, Cohen L | Acta Biochim Pol. 2004;51(2):373-8 | Targeting splicing by antisense oligonucleotides allows RNA modifications that are not possible w... | RNA modulation, repair and remodeling by splice switching oligonucleotides | not applicable | not applicable |
| Tucker RP | Acta Histochemica et Cytochemica, 2002, vol. 35, no. 5, pp. 361-366 | | Using Antisense Morpholino Oligos to Knockdown Gene Expression in the Chicken Embryo | | chick embryo |
| Yokota T, Duddy W, Partridge T | Acta Myol. 2007 Dec;26(3):179-84 | Exon skipping is one of the more promising therapeutic options for Duchenne Muscular Dystrophy (D... | Optimizing exon skipping therapies for DMD | | |
| Lebleu B, Moulton HM, Abes R, Ivanova GD, Abes S, Stein DA, Iversen PL, Arzumanov AA, Gait MJ | Adv Drug Deliv Rev. 2008 Mar 1;60(4-5):517-29. Epub 2007 Oct 22. | Charge neutral steric block oligonucleotide analogues, such as peptide nucleic acids (PNA) or pho... | Cell penetrating peptide conjugates of steric block oligonucleotides | peptide-coupled | various |
| Neuman BW, Stein DA, Kroeker AD, Moulton HM, Bestwick RK, Iversen PL, Buchmeier MJ | Adv Exp Med Biol. 2006;581:567-71 | No abstract available.
| Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers | | |
| Nagashima M, Saito J, Mawatari K, Mori Y, Matsukawa T, Koriyama Y, Kato S | Adv Exp Med Biol. 2010;664:517-24 | Recently, we cloned a photoreceptor-specific purpurin cDNA from axotomized goldfish retina. In th... | A hypoplastic retinal lamination in the purpurin knock down embryo in zebrafish | | zebrafish |
| Brand, R.M. and Iversen, P.L. | Advances Drug Devel. Reviews. 2000. 44(1): 51-57 | The potential for using antisense compounds as therapeutic agents has generated great enthusiasm.... | Transdermal delivery of antisense compounds | transdermal | not applicable |
| Nishimura DY, Swiderski RE, Searby CC, Berg EM, Ferguson AL, Hennekam R, Merin S, Weleber RG, Bie... | Am J Hum Genet. 2005 Dec;77(6):1021-33. Epub 2005 Oct 26 | Bardet-Biedl syndrome (BBS) is an autosomal recessive, genetically heterogeneous, pleiotropic hum... | Comparative genomics and gene expression analysis identifies BBS9, a new Bardet-Biedl syndrome ge... | | |
| Heuser A, Plovie ER, Ellinor PT, Grossmann KS, Shin JT, Wichter T, Basson CT, Lerman BB, Sasse-Kl... | Am J Hum Genet. 2006 Dec;79(6):1081-8. Epub 2006 Oct 3 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically heterogeneous heart-muscl... | Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy | | zebrafish |
| Asai-Coakwell M, French CR, Berry KM, Ye M, Koss R, Somerville M, Mueller R, van Heyningen V, Was... | Am J Hum Genet. 2007 Feb;80(2):306-15. Epub 2006 Dec 29 | Colobomata represent visually impairing ocular closure defects that are associated with a diverse... | GDF6, a Novel Locus for a Spectrum of Ocular Developmental Anomalies | | |
| Stoetzel C, Muller J, Laurier V, Davis EE, Zaghloul NA, Vicaire S, Jacquelin C, Plewniak F, Leitc... | Am J Hum Genet. 2007 Jan;80(1):1-11. Epub 2006 Nov 15 | Bardet-Biedl syndrome (BBS) is primarily an autosomal recessive ciliopathy characterized by progr... | Identification of a Novel BBS Gene (BBS12) Highlights the Major Role of a Vertebrate-Specific Bra... | | zebrafish |
| Valdmanis PN, Meijer IA, Reynolds A, Lei A, Macleod P, Schlesinger D, Zatz M, Reid E, Dion PA, Dr... | Am J Hum Genet. 2007 Jan;80(1):152-61. Epub 2006 Dec 1 | Hereditary spastic paraplegia (HSP) is a progressive upper-motor neurodegenerative disease. The e... | Mutations in the KIAA0196 Gene at the SPG8 Locus Cause Hereditary Spastic Paraplegia | | zebrafish |
| Ugarte M, Aguado C, Desviat LR, Sanchez-Alcudia R, Rincon A, Perez B | Am J Hum Genet. 2007 Oct 26;81(6) [Epub ahead of print] | We describe the use of antisense morpholino oligonucleotides (AMOs) to restore normal splicing ca... | Propionic and Methylmalonic Acidemia: Antisense Therapeutics for Intronic Variations Causing Aber... | | cell culture |
