Publications - Page 5
| Authors | Citation | Abstract | Title | Delivery Method | Organism |
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| Matson CW, Clark BW, Jenny MJ, Fleming CR, Hahn ME, Di Giulio RT | Aquat Toxicol. 2008 May 30;87(4):289-95. Epub 2008 Feb 23. | A significant challenge in environmental toxicology is that many genetic and genomic tools availa... | Development of the morpholino gene knockdown technique in Fundulus heteroclitus: A tool for study... | Microinjection | Fundulus heteroclitus |
| Froehlicher M, Liedtke A, Groh KJ, Neuhauss SC, Segner H, Eggen RI | Aquat Toxicol. 2009 Apr 24. [Epub ahead of print] | Aquatic toxicology is facing the challenge to assess the impact of complex mixtures of compounds ... | Zebrafish (Danio rerio) neuromast: Promising biological endpoint linking developmental and toxico... | | zebrafish |
| Clark BW, Matson CW, Jung D, Di Giulio RT | Aquat Toxicol. 2010 Aug 15;99(2):232-40 | Exposure of developing fish to polycyclic aromatic hydrocarbons (PAHs) and halogenated aromatic h... | AHR2 mediates cardiac teratogenesis of polycyclic aromatic hydrocarbons and PCB-126 in Atlantic k... | | Fundulus heteroclitus |
| Wills LP, Matson CW, Landon CD, Di Giulio RT | Aquat Toxicol. 2010 Aug 1;99(1):33-41. Epub 2010 Apr 14 | Fundulus heteroclitus (Atlantic killifish) found at the Atlantic Wood Industries Superfund site o... | Characterization of the recalcitrant CYP1 phenotype found in Atlantic killifish (Fundulus heteroc... | Microinjection | Fundulus heteroclitus |
| Teraoka H, Ogawa A, Kubota A, Stegeman JJ, Peterson RE, Hiraga T | Aquat Toxicol. 2010 May 7. [Epub ahead of print] | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) causes various signs of toxicity in early life stages ... | Malformation of certain brain blood vessels caused by TCDD activation of Ahr2/Arnt1 signaling in ... | | zebrafish |
| Scott JA, Incardona JP, Pelkki K, Shepardson S, Hodson PV | Aquat Toxicol. 2010 Oct 30. [Epub ahead of print] | In the embryo-larval stages of fish, alkylphenanthrenes such as retene (7-isopropyl-1-methylphena... | AhR2-mediated, CYP1A-independent cardiovascular toxicity in zebrafish (Danio rerio) embryos expos... | | zebrafish |
| Bugel SM, White LA, Cooper KR | Aquatic Toxicol. 2012;[Epub ahead of print] doi:10.1016/j.aquatox.2012.09.019 | Vitellogenins are hepatically derived yolk–protein precursors required for oogenesis in all ovipa... | Inhibition of vitellogenin gene induction by 2,3,7,8–tetrachlorodibenzo–p–dioxin is mediated by a... | Microinjection | zebrafish |
| Nimura T, Sueyoshi N, Ishida A, Yoshimura Y, Ito M, Tokumitsu H, Shigeri Y, Nozaki N, Kameshita I | Arch Biochem Biophys. 2007 Jan 15;457(2):205-16. Epub 2006 Nov 6 | Nuclear Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP-N) is an enzyme that dephos... | Knockdown of nuclear Ca(2+)/calmodulin-dependent protein kinase phosphatase causes developmental ... | | zebrafish |
| Shimomura S, Nagamine T, Nimura T, Sueyoshi N, Shigeri Y, Kameshita I | Arch Biochem Biophys. 2007 Jul 15;463(2):218-30. Epub 2007 Apr 12. | Doublecortin-like protein kinase (DCLK) is a protein Ser/Thr kinase expressed in brain and believ... | Expression, characterization, and gene knockdown of zebrafish doublecortin-like protein kinase | | zebrafish |
| Goldstone JV, Jönsson ME, Behrendt L, Woodin BR, Jenny MJ, Nelson DR, Stegeman JJ | Arch Biochem Biophys. 2008 Dec 10. [Epub ahead of print] | Enzymes in the cytochrome P450 1 family oxidize many common environmental toxicants. We identifie... | Cytochrome P450 1D1: A novel CYP1A-related gene that is not transcriptionally activated by PCB126... | | zebrafish |
| Sueyoshi N, Nimura T, Ishida A, Taniguchi T, Yoshimura Y, Ito M, Shigeri Y, Kameshita I | Arch Biochem Biophys. 2009 Jun 12. [Epub ahead of print] | Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) dephosphorylates and regulates mul... | Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) is indispensable for normal embryo... | Microinjection | zebrafish |
| Senga Y, Nagamine T, Kameshita I, Sueyoshi N | Arch Biochem Biophys. 2011 Nov 15. [Epub ahead of print] | We isolated cDNA clones for zebrafish Ca(2+)/calmodulin-dependent protein kinase I (zCaMKI) δ iso... | Knockdown of two splice variants of Ca(2+)/calmodulin-dependent protein kinase Iδ causes developm... | Microinjection | zebrafish |
| Yokota T, Takeda S, Lu QL, Partridge TA, Nakamura A, Hoffman EP | Arch Neurol. 2009 Jan;66(1):32-8 | Antisense oligonucleotides are short nucleic acid sequences designed for use as small-molecule dr... | A renaissance for antisense oligonucleotide drugs in neurology: exon skipping breaks new ground | | |
| Bohnsack BL, Gallina D, Thompson H, Kasprick DS, Lucarelli MJ, Dootz G, Nelson C, McGonnell IM, K... | Arch Ophthalmol. 2011 Apr 11. [Epub ahead of print] | Objectives To identify and explain morphologic changes of the extraocular muscles (EOMs) in anop... | Development of Extraocular Muscles Require Early Signals From Periocular Neural Crest and the Dev... | Microinjection | zebrafish |
| Selzer M, Zhang G, Lin LQ | Arch Phys Med Rehabil. 2006 Oct;87(10):e1 | Objective: To determine the role of neurofilament in central nervous system (CNS) axon regenerati... | Article 2: Inhibition of Neurofilament Synthesis by Morpholino Antisense Oligonucleotides Inhibit... | spinal transection and retrograde transport to brain stem | Lamprey |
| Lupfer C, Stein DA, Mourich DV, Tepper SE, Iversen PL, Pastey M | Arch Virol. 2008 May;153(5):929-37. Epub 2008 Mar 28. | New methods to combat influenza A virus (FLUAV) in humans and animals are needed. The H3N8 subtyp... | Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers | Peptide-coupled intranasal | mice |
| Gray C, Packham IM, Wurmser F, Eastley NC, Hellewell PG, Ingham PW, Crossman DC, Chico TJA | Arterioscler Thromb Vasc Biol, Oct 2007; 27: 2135 - 2141 | Objective— The role of ischemia in collateral vessel development (arteriogenesis) is a contentiou... | Ischemia Is Not Required for Arteriogenesis in Zebrafish Embryos | | zebrafish |
| Lin Y, Zhu X, McLntee FL, Xiao H, Zhang J, Fu M, Chen YE | Arterioscler Thromb Vasc Biol. 2003 Dec 1 [Epub ahead of print] | OBJECTIVE: Peroxisome proliferator-activated receptor gamma (PPARgamma) possesses general benefic... | Interferon Regulatory Factor-1 Mediates PPAR{gamma}-Induced Apoptosis in Vascular Smooth Muscle C... | Special Delivery | cell culture: rat aortic smooth muscle cells |
| Zhang S, Ren J, Khan MF, Cheng AM, Abendschein D, Muslin AJ | Arterioscler Thromb Vasc Biol. 2003 Jul 3 [Epub ahead of print] | OBJECTIVE: Neointima formation occurs in arteries in response to mechanical or chemical injury an... | Grb2 Is Required for the Development of Neointima in Response to Vascular Injury | Scrape Delivery | cell culture: rat aortic smooth muscle cells |
| Pini B, Grosser T, Lawson JA, Price TS, Pack MA, Fitzgerald GA | Arterioscler Thromb Vasc Biol. 2005 Feb;25(2):315-20. Epub 2004 Dec 2. | OBJECTIVE: Prostaglandin E synthases (PGESs) are being explored as antiinflammtory drug targets a... | Prostaglandin E Synthases in Zebrafish | not published | zebrafish |
| Guan Z, Basi D, Li Q, Mariash A, Xia YF, Geng J, Kao E, Hall JL | Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):96-101. Epub 2004 Nov 11. | OBJECTIVE: The aim of this project was to test the hypothesis that redox factor 1 (Ref-1) was a c... | Loss of Redox Factor 1 Decreases NF-kappaB Activity and Increases Susceptibility of Endothelial C... | Special Delivery | cell culture: Bovine pulmonary endothelial cells |
| Wu X, Zhong H, Song J, Damoiseaux R, Yang Z, Lin S | Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2414-6 | No abstract available | Mycophenolic acid is a potent inhibitor of angiogenesis | | |
| Mariappan D, Niemann R, Gajewski M, Winkler J, Chen S, Choorapoikayil S, Bitzer M, Schulz H, Hesc... | Arterioscler Thromb Vasc Biol. 2009 Jun 18. [Epub ahead of print] | OBJECTIVE: We recently isolated and characterized endothelial-like CD31(+) cells derived from mou... | Somitovasculin, a Novel Endothelial-Specific Transcript Involved in the Vasculature Development | | zebrafish |
| Geudens I, Herpers R, Hermans K, Segura I, Ruiz de Almodovar C, Bussmann J, De Smet F, Vandevelde... | Arterioscler Thromb Vasc Biol. 2010 May 13. [Epub ahead of print] | OBJECTIVE: To study whether Notch signaling, which regulates cell fate decisions and vessel morph... | Role of Dll4/Notch in the Formation and Wiring of the Lymphatic Network in Zebra Fish | Microinjection | zebrafish |
| McGuire PG, Rangasamy S, Maestas J, Das A | Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):e107-15. Epub 2011 Sep 22 | OBJECTIVE:
The mechanisms that regulate the physical interaction of pericytes and endothelial ce... | Pericyte-derived sphingosine 1-phosphate induces the expression of adhesion proteins and modulate... | Endo-Porter | cell culture: human retinal cells |
| Rissone A, Foglia E, Sangiorgio L, Cermenati S, Nicoli S, Cimbro S, Beltrame M, Bussolino F, Cote... | Arterioscler Thromb Vasc Biol. 2012 Apr 19. [Epub ahead of print] | OBJECTIVE:
The goal of this study was to determine the in vivo functions of the synaptic protein... | The Synaptic Proteins β-Neurexin and Neuroligin Synergize With Extracellular Matrix-Binding Vascu... | Microinjection | zebrafish |
| Huang H, Jin T, He J, Ding Q, Xu D, Wang L, Zhang Y, Pan Y, Wang Z, Chen Y | Arterioscler Thromb Vasc Biol. 2012 Jul 19. [Epub ahead of print] | OBJECTIVE:
Progesterone and adipoQ receptor (PAQR) 10 and PAQR11 are 2 highly homologous genes i... | Progesterone and AdipoQ Receptor 11 Links Ras Signaling to Cardiac Development in Zebrafish | Microinjection | zebrafish |
| Tobia C, Chiodelli P, Nicoli S, Dell’Era P, Buraschi S, Mitola S, Foglia E, van Loenen PB, Alewij... | Arterioscler Thromb Vasc Biol. 2012;[Epub ahead of print] doi:10.1161/ATVBAHA.112.250035 | Objective—Endothelial sphingosine-1-phosphate (S1P) receptor-1 (S1P1) affects different vascular ... | Sphingosine-1-Phosphate Receptor-1 Controls Venous Endothelial Barrier Integrity in Zebrafish | Microinjection | zebrafish |
| Csányi G, Yao M, Rodriguez AI, Al Ghouleh I, Sharifi-Sanjani M, Frazziano G, Xiaojun H, Kelley EE... | Arterioscler Thromb Vasc Biol. 2012;[Epub ahead of print] doi:10.1161/ATVBAHA.112.300031 | Objective—Although the matricellular protein thrombospondin-1 (TSP1) is highly expressed in the v... | Thrombospondin-1 Regulates Blood Flow via CD47 Receptor–Mediated Activation of NADPH Oxidase 1 | Vivo-Morpholino | rat, Sprague Dawley, male |
| Gray C, Bratt D, Lees J, Dacosta M, Plant K, Solaymani-Kohal S, Tazzyman S, Serbanovic-Canic J, C... | Arterioscler Thromb Vasc Biol. 2013 Apr 4. [Epub ahead of print] | OBJECTIVE: Coarctation of the aorta is rarely associated with known gene defects. Blomstrand chon... | Loss of Function of Parathyroid Hormone Receptor 1 Induces Notch-Dependent Aortic Defects During ... | Microinjection | zebrafish |
| Kaluza D, Kroll J, Gesierich S, Manavski Y, Boeckel JN, Doebele C, Zelent A, Rössig L, Zeiher AM,... | Arterioscler Thromb Vasc Biol. 2013 Jan 3. [Epub ahead of print] | OBJECTIVE:
Histone deacetylases (HDACs) modulate gene expression by deacetylation of histone and... | Histone Deacetylase 9 Promotes Angiogenesis by Targeting the Antiangiogenic MicroRNA 17-92 Cluste... | Microinjection | zebrafish |
| Cermenati S, Moleri S, Neyt C, Bresciani E, Carra S, Grassini DR, Omini A, Goi M, Cotelli F, Fran... | Arterioscler Thromb Vasc Biol. 2013 Mar 21. [Epub ahead of print] | OBJECTIVE: Lymphangiogenesis is regulated by transcription factors and by growth factor pathways,... | Sox18 Genetically Interacts With VegfC to Regulate Lymphangiogenesis in Zebrafish | Microinjection | zebrafish |
| Zhao Y, Lin S | Arterioscler Thromb Vasc Biol. 2013 Mar 28. [Epub ahead of print] | OBJECTIVE: Studying the underlying molecular mechanisms for maintaining stereotyped vascular lume... | Essential Role of Sh3gl3 for Vascular Lumen Maintenance in Zebrafish | Microinjection | zebrafish |
| Isenberg, J. S., Hyodo, F., Pappan, L. K., Abu-Asab, M., Tsokos, M., Frazier, W. A., Krishna, M.... | Arterioscler. Thromb. Vasc. Biol. 27:2582-2588, 2007 | OBJECTIVE: Decreased blood flow secondary to peripheral vascular disease underlies a significant ... | Blocking thrombospondin-1/CD47 signaling alleviates deleterious effects of aging on tissue respon... | In vitro: transfection; in vivo: intramuscular injection | mice |
| Hu Z, Zhang J, Zhang Q | Autophagy. 2011 Dec 1;7(12). [Epub ahead of print] | The implications of autophagy related genes in serious neural degenerative diseases have been wel... | Expression pattern and functions of autophagy-related gene atg5 in zebrafish organogenesis | Microinjection | zebrafish |
| Soto-Pantoja DR, Miller TW, Pendrak ML, Degraff WG, Sullivan C, Ridnour LA, Abu-Asab M, Wink DA, ... | Autophagy. 2012 Nov 1;8(11). [Epub ahead of print] | Accidental or therapeutic exposure to ionizing radiation has severe physiological consequences an... | CD47 deficiency confers cell and tissue radioprotection by activation of autophagy | | |
| Benato F, Skobo T, Gioacchini G, Moro I, Ciccosanti F, Piacentini M, Fimia GM, Carnevali O, Valle... | Autophagy. 2013 Jan 24;9(4). [Epub ahead of print] | AMBRA1 is a positive regulator of the BECN1-dependent program of autophagy recently identified in... | Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogene... | | zebrafish |
| Hoffmann S, Berger IM, Glaser A, Bacon C, Li L, Gretz N, Steinbeisser H, Rottbauer W, Just S, Rap... | Basic Res Cardiol. 2013 Mar;108(2):339. doi: 10.1007/s00395-013-0339-z. Epub 2013 Mar 1 | The heart’s rhythm is initiated and regulated by a group of specialized cells in the sinoatrial n... | Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescu... | Microinjection | zebrafish |
| Mol Cell Biol. 2006 Dec;26(24):9291-301. Epub 2006 Sep 25. | Beekman C, Nichane M, De Clercq S, Maetens M, Floss T, Wurst W, Bellefroid E, Marine JC. | Nucleostemin (NS) is a putative GTPase expressed preferentially in the nucleoli of neuronal and e... | Evolutionarily conserved role of nucleostemin: controlling proliferation of stem/progenitor cells... | Microinjection | Xenopus |
| Snider AC, Leong D, Wang QT, Wysocka J, Yao MWM, Scott MP | Bio Open. 2012;Advance Online Publication doi:10.1242/bio.20122949 | During preimplantation development, the embryo must establish totipotency and enact the earliest ... | The chromatin remodeling factor Chd1l is required in the preimplantation embryo | Microinjection | Mouse embryo |
| Bubenshchikova E, Ichimura K, Fukuyo Y, Powell R, Hsu C, Morrical SO, Sedor JR, Sakai T, Obara T | Bio Open. 2012;[Advance Online Publication] doi:10.1242/bio.20121016 | Defects in cilia and basal bodies function are linked to ciliopathies, which result in kidney cys... | Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis | Microinjection | zebrafish |
| Hisano Y, Ota S, Arakawa K, Muraki M, Kono N, Oshita K, Sakuma T, Tomita M, Yamamoto T, Okada Y, ... | Bio Open. 2013;[Epub ahead of print] doi:10.1242/bio.20133871 | Artificially designed nucleases such as zinc-finger nucleases (ZFNs) and transcription activator-... | Quantitative assay for TALEN activity at endogenous genomic loci | | zebrafish |
| Yao Z, Farr III GH, Tapscott SJ, Maves L | Bio Open. 2013;[Epub ahead of print] doi:10.1242/bio.20133921 | The basic helix–loop–helix factor Myod initiates skeletal muscle differentiation by directly and ... | Pbx and Prdm1a transcription factors differentially regulate subsets of the fast skeletal muscle ... | Microinjection | zebrafish |
| Sun SC, Liu HL, Sun QY | Biochem Biophys Res Comm. 2012;[Epub ahead of print] | Survivin is a member of inhibitors of apoptosis proteins (IAPs), and also belongs to be a member ... | Survivin regulates Plk1 localization to kinetochore in mouse oocyte meiosis | Microinjection | mouse oocytes |
| Yang J, Zeng Z, Wei J, Jiang L, Ma Q, Wu M, Huang X, Ye S, Li Y, Ma D, Gao Q | Biochem Biophys Res Comm. 2013;[Epub ahead of print] doi:10.1016/j.bbrc.2013.02.085 | Semaphorin4d (SEMA4D), also known as CD100, an oligodendrocyte secreted R-Ras GTPase-activating p... | Sema4d Is Required for the Development of the Hindbrain boundary and Skeletal Muscle in Zebrafish | Microinjection | zebrafish |
| Ding, X-Z, Iversen, P., Cluck, M.W., Knezetic, J.A. and Adrian, T.E. | Biochem Biophys Res Commun 1999 Jul 22;261(1):218-23 | Epidemiologic and animal studies have linked pancreatic cancer growth with fat intake, especially... | Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells | Scrape Delivery | cell culture: human pancreatic cancer cell lines |
| Lacroix L, Arimondo PB, Takasugi M, Helene C, Mergny JL | Biochem Biophys Res Commun 2000 Apr 13;270(2):363-9 | Oligonucleotides can be used as sequence-specific DNA ligands by forming a local triple helix. In... | Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ion... | not applicable | not applicable |
| Satow R, Chan TC, Asashima M | Biochem Biophys Res Commun 2002 Jul 5;295(1):85-91 | In a screen for genes expressed in neural tissues and pronephroi, we isolated a novel gene, named... | Molecular cloning and characterization of dullard: a novel gene required for neural development | Microinjection | Xenopus |
| Teraoka H, Dong W, Tsujimoto Y, Iwasa H, Endoh D, Ueno N, Stegeman JJ, Peterson RE, Hiraga T | Biochem Biophys Res Commun 2003 May 2;304(2):223-8 | The mechanism of toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is thought to result from... | Induction of cytochrome P450 1A is required for circulation failure and edema by 2,3,7,8-tetrachl... | Microinjection | zebrafish |
| Ussat S, Werner UE, Kruse ML, Luschen S, Scherer G, Kabelitz D, Adam-Klages S | Biochem Biophys Res Commun. 2002 Jun 14;294(3):672-9 | The molecular mechanisms mediating death receptor-induced caspase-independent necrotic cell death... | Upregulation of p21(WAF1/Cip1) precedes tumor necrosis factor-induced necrosis-like cell death | Special Delivery | cell culture: NIH-3T3 cells |
