Publications - Page 1
| Authors | Citation | Abstract | Title | Delivery Method | Organism |
|---|
| Shimizu T, Yamanaka Y, Nojima H, Yabe T, Hibi M, Hirano T | Mech Dev. 2002 Oct;118(1-2):125 | Dharma/Bozozok (Dha/Boz) is a homeodomain protein containing an Engrailed homology (Eh) 1 repress... | A novel repressor-type homeobox gene, ved, is involved in dharma/bozozok-mediated dorsal organiz... | Microinjection | zebrafish |
| Olesnicky Killian EC, Birkholz DA, Artinger KB | Dev Biol. 2009 Sep 1;333(1):161-72. Epub 2009 Jul 1 | Neural crest cells (NCCs) are a unique population of multipotent cells that migrate along defined... | A role for chemokine signaling in neural crest cell migration and craniofacial development | Microinjection | zebrafish |
| Masumoto J, Zhou W, Chen FF, Su F, Kuwada JY, Hidaka E, Katsuyama T, Sagara J, Taniguchi S, Ngo-H... | J Biol Chem. 2003 Feb 7;278(6):4268-76. Epub 2002 Dec 02. | The pyrin domain was identified recently in multiple proteins that are associated with apoptosis ... | Caspy: A Zebrafish caspase activated by ASC oligomerization required for pharyngeal Arch develop... | Microinjection | zebrafish |
| Kawachi K, Masuyama N, Nishida E | J Biol Chem. 2003 Feb 14;278(7):5473-7. Epub 2002 Dec 04 | The fibroblast growth factor (FGF)/MAPK pathway plays an important role in early Xenopus developm... | Essential role of the transcription factor Ets-2 in Xenopus early development | Microinjection | Xenopus |
| Maves L, Jackman W, Kimmel CB | Development. 2002. 129(16):3825-3837 | The segmentation of the vertebrate hindbrain into rhombomeres is highly conserved, but how early ... | FGF3 and FGF8 mediate a rhombomere 4 signaling activity in the zebrafish hindbrain | Microinjection | zebrafish |
| Qin G, Taylor M, Ning YY, Iversen P, Kobzik L | Antisense Nucleic Acid Drug Dev 2000 Feb;10(1):11-6 | Morpholino antisense oligomers directed against the cytokine tumor necrosis factor (TNF-alpha) ca... | In vivo evaluation of a morpholino antisense oligomer directed against tumor necrosis factor-alp... | in vivo: intranasal | BALB/c mice |
| Summerton J and Dwight Weller | Antisense & Nucleic Acid Drug Development 1997 7:187-195 | Antisense promised major advances in treating a broad range of intractable diseases, but in recen... | Morpholino Antisense Oligomers: Design, Preparation and Properties. | | |
| Agathon A, Thisse B, Thisse C | Genesis. 2001 Jul;30(3):178-82 | No abstract available | Morpholino knock-down of antivin1 and antivin2 upregulates nodal signaling | Microinjection | zebrafish |
| Lele Z, Bakkers J, Hammerschmidt M. | Genesis. 2001 Jul;30(3):190-4 | No abstract available. | Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail m... | Microinjection | zebrafish |
| Nishi E, Prat A, Hospital V, Elenius K, Klagsbrun M. | EMBO J 2001 Jul 2;20(13):3342-3350 | Heparin-binding epidermal growth factor-like growth factor (HB-EGF), a mitogen and chemotactic fa... | N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor ... | Special Delivery | cell culture: HaCaT keratinocytes |
| Shumay E, Song X, Wang HY, Malbon CC | Mol Biol Cell. 2002 Nov;13(11):3943-54 | Insulin stimulates a rapid phosphorylation and sequestration of the beta(2)-adrenergic receptor. ... | pp60Src Mediates Insulin-stimulated Sequestration of the beta(2)-Adrenergic Receptor: Insulin St... | Special Delivery | cell culture: Human epidermoid carcinoma A431 |
| Devi GR | Curr Opin Mol Ther. 2002 Apr;4(2):138-48. Review. | Prostate cancer, like most other solid tumors, represents a heterogeneous entity consisting of a ... | Prostate cancer: status of current treatments and emerging antisense-based therapies | | |
| Parsons MJ, Campos I, Hirst EM, Stemple DL | Development 2002 Jul;129(14):3505-12 | Muscular dystrophy is frequently caused by disruption of the dystrophin-glycoprotein complex (DGC... | Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos. | Microinjection | zebrafish |
| Sugiyama S, Nakamura H | Development. 2003 Feb 1;130(3):451-462 | Mature chick optic tecta consist of 16 laminae and receive retinal fiber projections in a precise... | The role of Grg4 in tectal laminar formation | Electroporation | chick embryo |
| Topczewska JM, Topczewski J, Shostak A, Kume T, Solnica-Krezel L, Hogan BL. | Genes Dev. 2001 Sep 15;15(18):2483-93 | Previous studies identified zebrafish foxc1a and foxc1b as homologs of the mouse forkhead gene, F... | The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish | Microinjection | zebrafish |
| Stalmans I, Lambrechts D, De Smet F, Jansen S, Wang J, Maity S, Kneer P, Von Der Ohe M, Swillen A... | Nat Med. 2003 Feb;9(2):173-82 | Hemizygous deletion of chromosome 22q11 (del22q11) causes thymic, parathyroid, craniofacial an... | VEGF: A modifier of the del22q11 (DiGeorge) syndrome? | Microinjection | zebrafish |
| Tran HT, Sekkali B, Van Imschoot G, Janssens S, Vleminckx K | Proc Natl Acad Sci U S A. 2010 Aug 30. [Epub ahead of print] | The formation of primitive (embryonic) blood in vertebrates is mediated by spatio-temporally rest... | Wnt/beta-catenin signaling is involved in the induction and maintenance of primitive hematopoies... | | Xenopus |
| Frazzetto G, Klingbeil P, Bouwmeester T | Mech Dev. 2002 Apr;113(1):3-14 | Gastrulation in vertebrates is a highly dynamic process driven by convergent extension movements ... | Xenopus marginal coil (Xmc), a novel FGF inducible cytosolic coiled-coil protein regulating gast... | Microinjection | Xenopus laevis |
| Dibner C, Elias S, Frank D | Development. 2001 Sep;128(18):3415-26 | Meis-family homeobox proteins have been shown to regulate cell fate specification in vertebrate a... | XMeis3 protein activity is required for proper hindbrain patterning in Xenopus laevis embryos | Microinjection | Xenopus |
| Hunter MP, Prince VE | Dev Biol. 2002 Jul 15;247(2):367-389 | The pharyngeal arches are one of the defining features of the vertebrates, with the first arch fo... | Zebrafish Hox Paralogue Group 2 Genes Function Redundantly as Selector Genes to Pattern the Seco... | Microinjection | zebrafish |
| Muraoka O | Nippon Yakurigaku Zasshi. 2002 Aug;120(2):96-100. Japanese. | The technology for the control of gene function is necessary not only to study development, but a... | [The new technology for controlling gene function in zebrafish] | not applicable | not applicable |
| Luo KL, Luo JH, Yu YP | Cancer Sci. 2009. [Epub ahead of print] | (-)-Epigallocatechin-3-gallate (EGCG) is one of the major polyphenol components in green tea. It ... | (-)-Epigallocatechin-3-gallate induces Du145 prostate cancer cell death via downregulation of inh... | | cell culture: human prostate cancer cell line Du145 |
| Sumanas S, Zhang B, Dai R, Lin S | Dev Biol. 2005 Jul 1;283(1):85-96. | A novel zebrafish gene bloody fingers (blf) encoding a 478 amino acid protein containing fifteen ... | 15-Zinc finger protein Bloody Fingers is required for zebrafish morphogenetic movements during ne... | Microinjection | zebrafish |
| Carney SA, Peterson RE, Heideman W | Mol Pharmacol. 2004 Sep;66(3):512-21 | The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that dimerizes wit... | 2,3,7,8-Tetrachlorodibenzo-p-dioxin Activation of the Aryl Hydrocarbon Receptor/Aryl Hydrocarbon ... | Microinjection | zebrafish |
| Bello SM, Heideman W, Peterson RE | Toxicol Sci. 2004 Apr;78(2):258-66. | A role for the aryl hydrocarbon receptor (AHR) pathway in vascular maturation has been implicated... | 2,3,7,8-Tetrachlorodibenzo-p-dioxin Inhibits Regression of the Common Cardinal Vein in Developing... | Microinjection | zebrafish |
| Planchart A, Mattingly CJ | Chem Res Toxicol. 2010 Jan 7. [Epub ahead of print] | Vertebrate jaw development can be disrupted by exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (T... | 2,3,7,8-Tetrachlorodibenzo-p-dioxin Upregulates FoxQ1b in Zebrafish Jaw Primordium | | zebrafish |
| De Lucchini S, Ori M, Cremisi F, Nardini M, Nardi I | Mol Cell Neurosci. 2005 Jun;29(2):299-312 | In this paper, we show that serotonin, via 5-HT2B receptor, is involved in Xenopus retinal histog... | 5-HT2B-mediated serotonin signaling is required for eye morphogenesis in Xenopus | Microinjection | Xenopus |
| Jost JP, Oakeley EJ, Zhu B, Benjamin D, Thiry S, Siegmann M, Jost YC | Nucleic Acis Res 2001 Nov 1 29(21):4452-4461 | Changes in gene expression during mouse myoblast differentiation were monitored by DNA microarray... | 5-Methycytosine DNA glycosylase participates in the genome-wide loss of DNA methylation occurring... | Special Delivery | cell culture: mouse G8 myoblasts |
| Barboric M, Lenasi T, Chen H, Johansen EB, Guo S, Peterlin BM | Proc Natl Acad Sci U S A. 2009 Apr 27. [Epub ahead of print] | Eukaryotic gene expression is commonly controlled at the level of RNA polymerase II (RNAPII) paus... | 7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for ... | | zebrafish |
| Machingo QJ, Fritz A, Shur BD | Development. 2006 Jun;133(11):2233-41. Epub 2006 May 3. | Complex carbohydrates are highly polymorphic macromolecules that are involved in diverse biologic... | A beta1,4-galactosyltransferase is required for Bmp2-dependent patterning of the dorsoventral axi... | Microinjection | zebrafish |
| Machingo QJ, Fritz A, Shur BD | Dev Biol. 2006 Sep 15;297(2):471-82. Epub 2006 May 27 | Our understanding of how complex carbohydrates function during embryonic development is still ver... | A beta1,4-galactosyltransferase is required for convergent extension movements in zebrafish | Microinjection | zebrafish |
| Liu J, Fraser SD, Faloon PW, Rollins EL, Vom Berg J, Starovic-Subota O, Laliberte AL, Chen JN, Se... | Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):13990-5. Epub 2007 Jun 15 | The vasculature tailors to the needs of different tissues and organs. Molecular, structural, and ... | A betaPix-Pak2a signaling pathway regulates cerebral vascular stability in zebrafish | | zebrafish |
| Tokuoka M, Satoh N, Satou Y | Dev Biol. 2005 Dec 15;288(2):387-96. Epub 2005 Nov 11. | Ascidian larval mesenchyme cells, comprising about 900 cells, are derived from the A7.6, B8.5 and... | A bHLH transcription factor gene, Twist-like1, is essential for the formation of mesodermal tissu... | Microinjection | Ciona savignyi |
| Seguchi O, Takashima S, Yamazaki S, Asakura M, Asano Y, Shintani Y, Wakeno M, Minamino T, Kondo H... | J Clin Invest. 2007 Oct;117(10):2812-24. | Marked sarcomere disorganization is a well-documented characteristic of cardiomyocytes in the fai... | A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart | | zebrafish |
| Topp JD, Jackson J, Melton AA, Lynch KW | RNA. 2008 Aug 21. [Epub ahead of print] | The human CD45 gene encodes a protein-tyrosine phosphatase that exhibits differential isoform exp... | A cell-based screen for splicing regulators identifies hnRNP LL as a distinct signal-induced repr... | Electroporation | cell culture: human JSL1 T-cell line |
| Horne-Badovinac S, Rebagliati M, Stainier DY | Science. 2003 Oct 24;302(5645):662-5 | Many vertebrate organs adopt asymmetric positions with respect to the midline, but little is know... | A cellular framework for gut-looping morphogenesis in zebrafish | Microinjection | zebrafish |
| Zoeller JJ, McQuillan A, Whitelock J, Ho SY, Iozzo RV | J Cell Biol. 2008 Apr 21;181(2):381-94 | Perlecan's developmental functions are difficult to dissect in placental animals because perlecan... | A central function for perlecan in skeletal muscle and cardiovascular development | | zebrafish |
| Zoeller JJ, Pimtong W, Corby H, Goldoni S, Iozzo AE, Owens RT, Ho SY, Iozzo RV | J Biol Chem. 2009 Feb 10. [Epub ahead of print] | Decorin, an archetypal member of the small leucine-rich proteoglycan gene family, regulates colla... | A central role for decorin during vertebrate convergent extension | | zebrafish |
| Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, Cirone P, Griesbach HL, Schneider I, Slusarski DC, Holle... | Chem Biol. 2006 Sep;13(9):1001-9 | Previous mode of action studies identified methionine aminopeptidase 2 (MetAP-2) as the target of... | A chemical and genetic approach to the mode of action of fumagillin | Microinjection | zebrafish |
| Tomlinson ML, Guan P, Morris RJ, Fidock MD, Rejzek M, Garcia-Morales C, Field RA, Wheeler GN | Chem Biol. 2009 Jan 30;16(1):93-104 | To dissect the function of matrix metalloproteinases (MMPs) involved in cellular migration in viv... | A chemical genomic approach identifies matrix metalloproteinases as playing an essential and spec... | | Xenopus laevis |
| Rothbächer U, Bertrand V, Lamy C, Lemaire P | Development. 2007 Nov;134(22):4023-32 | Our understanding of the maternal factors that initiate early chordate development, and of their ... | A combinatorial code of maternal GATA, Ets and beta-catenin-TCF transcription factors specifies a... | | Ciona intestinalis |
| Khanna H, Davis EE, Murga-Zamalloa CA, Estrada-Cuzcano A, Lopez I, den Hollander AI, Zonneveld M... | Nat Genet. 2009 Jun;41(6):739-45. Epub 2009 May 10 | Despite rapid advances in the identification of genes involved in disease, the predictive power o... | A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies | Microinjection | zebrafish |
| He J, Liu G, Zhang S, Vanderheyden JL, Liu N, Liu C, Zhang Y, Gupta S, Rusckowski M, Hnatowich DJ | Bioconjug Chem. 2003 Sep-Oct;14(5):1018-23 | The stability of hybridized duplexes is an important criterion for any radiopharmaceutical applic... | A comparison of in vitro and in vivo stability in mice of two morpholino duplexes differing in ch... | in vivo: injection | male CD-1 mice |
| Vasil ML, Stonehouse MJ, Vasil AI, Wadsworth SJ, Goldfine H, Bolcome RE 3rd, Chan J | PLoS Pathog. 2009 May;5(5):e1000420. Epub 2009 May 8 | The hemolytic phospholipase C (PlcHR) expressed by Pseudomonas aeruginosa is the original member ... | A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selec... | | zebrafish |
| Kato Y, Habas R, Katsuyama Y, Naar AM, He X | Nature. 2002 Aug 8;418(6898):641-6 | The transforming growth factor beta (TGF beta) family of cytokines, including Nodal, Activin and ... | A component of the ARC/Mediator complex required for TGF beta/Nodal signalling | Microinjection | Xenopus laevis |
| Swiers G, Chen YH, Johnson AD, Loose M | Dev Biol. 2010 Apr 13. [Epub ahead of print] | Understanding how mesoderm is specified during development is a fundamental issue in biology, and... | A conserved mechanism for vertebrate mesoderm specification in urodele amphibians and mammals | Microinjection | Axolotl |
| Srinivas BP, Woo J, Leong WY, Roy S | Nat Genet. 2007 Jun;39(6):781-6. Epub 2007 May 27 | Skeletal muscles arise by fusion of precursor cells, myoblasts, into multinucleated fibers. In ve... | A conserved molecular pathway mediates myoblast fusion in insects and vertebrates | | zebrafish |
| Tang J, Hu G, Hanai JI, Yadlapalli G, Lin Y, Zhang B, Galloway J, Bahary N, Sinha S, Thisse B, Th... | J Biol Chem. 2006 Mar 10;281(10):6664-72. Epub 2005 Nov 28. | Calponin 2 (h2 calponin, CNN2) is an actin-binding protein implicated in cytoskeletal organizatio... | A critical role for calponin 2 in vascular development | Microinjection | zebrafish |
| Vlecken DH, Testerink J, Ott EB, Sakalis PA, Jaspers RT, Bagowski CP | Int J Dev Biol. 2009 Apr 2. [Epub ahead of print] | The globin family, including hemoglobin, myoglobin, neuroglobin and cytoglobin, plays an importan... | A critical role for myoglobin in zebrafish development | | zebrafish |
| Dickmeis T, Mourrain P, Saint-Etienne L, Fischer N, Aanstad P, Clark M, Strahle U, Rosa F | Genes Dev. 2001 Jun 15;15(12):1487-92 | casanova (cas) mutant zebrafish embryos lack endoderm and develop cardia bifida. In a substractiv... | A crucial component of the endoderm formation pathway, CASANOVA, is encoded by a novel sox-relate... | Microinjection | zebrafish |
