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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
Inactivating negative regulators of cortical branched actin enhances persistence of single cell migration
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Citation:
J Cell Sci. 2023 Dec 7:jcs.261332. doi: 10.1242/jcs.261332. Online ahead of print Epub:
Yes Abstract:
The Rac1-WAVE-Arp2/3 pathway pushes the plasma membrane by polymerizing branched actin, thereby powering membrane protrusions... Citation Extract: Fokin AI, Boutillon A, James J, Courtois L, Vacher S, Simanov G, Wang Y, Polesskaya A, Bièche I, David NB, Gautreau AM. Inactivating negative regulators of cortical branched actin enhances persistence of single cell migration. J Cell Sci. 2023 Dec 7:jcs.261332. doi: 10.1242/jcs.261332. Online ahead of print. |
Transmembrane protein 14A protects glomerular filtration barrier integrity
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Citation:
Physiol Rep. 2023 Dec;11(23):e15847. doi: 10.14814/phy2.15847 Epub:
Not Epub Abstract:
Transmembrane protein 14A (TMEM14A) is a relatively unknown protein that is now identified to be required for maintaining the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Khalil R, Bonnemaijer JDD, Kreutz R, Spaink HP, Hogendoorn PCW, Baelde HJ. Transmembrane protein 14A protects glomerular filtration barrier integrity. Physiol Rep. 2023 Dec;11(23):e15847. doi: 10.14814/phy2.15847. |
A cell-and-plasma numerical model reveals hemodynamic stress and flow adaptation in zebrafish microvessels after morphological alteration
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Citation:
PLoS Comput Biol. 2023 Dec 4;19(12):e1011665. doi: 10.1371/journal.pcbi.1011665. Online ahead of print Epub:
Not Epub Abstract:
The development of a functional cardiovascular system ensures a sustainable oxygen, nutrient and hormone delivery system for... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Maung Ye SS, Phng LK. A cell-and-plasma numerical model reveals hemodynamic stress and flow adaptation in zebrafish microvessels after morphological alteration. PLoS Comput Biol. 2023 Dec 4;19(12):e1011665. doi: 10.1371/journal.pcbi.1011665. Online ahead of print. |
Selenoprotein deficiency disorder predisposes to aortic aneurysm formation
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Citation:
Nat Commun. 2023 Dec 2;14(1):7994. doi: 10.1038/s41467-023-43851-6 Epub:
Not Epub Abstract:
Aortic aneurysms, which may dissect or rupture acutely and be lethal, can be a part of multisystem disorders that have a... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schoenmakers E, Marelli F, Jørgensen HF, Visser WE, Moran C, Groeneweg S, Avalos C, Jurgens SJ, Figg N, Finigan A, Wali N, Agostini M, Wardle-Jones H, Lyons G, Rusk R, Gopalan D, Twiss P, Visser JJ, Goddard M, Nashef SAM, Heijmen R, Clift P, Sinha S, Pirruccello JP, Ellinor PT, Busch-Nentwich EM, Ramirez-Solis R, Murphy MP, Persani L, Bennett M, Chatterjee K. Selenoprotein deficiency disorder predisposes to aortic aneurysm formation. Nat Commun. 2023 Dec 2;14(1):7994. doi: 10.1038/s41467-023-43851-6. |
Efficacy of exon-skipping therapy for DMD cardiomyopathy with mutations in actin binding domain 1
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Citation:
Mol Ther Nucleic Acids. 2023 Oct 19;34:102060. doi: 10.1016/j.omtn.2023.102060. eCollection 2023 Dec 12 Epub:
Not Epub Abstract:
Exon-skipping therapy is a promising treatment strategy for Duchenne muscular dystrophy (DMD), which is caused by loss-of-... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: hiPSC-CMs Citation Extract: Shiba N, Yang X, Sato M, Kadota S, Suzuki Y, Agata M, Nagamine K, Izumi M, Honda Y, Koganehira T, Kobayashi H, Ichimura H, Chuma S, Nakai J, Tohyama S, Fukuda K, Miyazaki D, Nakamura A, Shiba Y. Efficacy of exon-skipping therapy for DMD cardiomyopathy with mutations in actin binding domain 1. Mol Ther Nucleic Acids. 2023 Oct 19;34:102060. doi: 10.1016/j.omtn.2023.102060. eCollection 2023 Dec 12. |
A Role for Two-Pore Channel Type 2 (TPC2)-Mediated Regulation of Membrane Contact Sites During Zebrafish Notochord Biogenesis?
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Citation:
Contact (Thousand Oaks). 2023 Nov 7;6:25152564231211409. doi: 10.1177/25152564231211409 Epub:
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We have previously shown that in the developing trunk of zebrafish embryos, two-pore channel type 2 (TPC2)-mediated Ca2+... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rice KL, Chan CM, Kelu JJ, Miller AL, Webb SE. A Role for Two-Pore Channel Type 2 (TPC2)-Mediated Regulation of Membrane Contact Sites During Zebrafish Notochord Biogenesis?. Contact (Thousand Oaks). 2023 Nov 7;6:25152564231211409. doi: 10.1177/25152564231211409. |
Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation
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Citation:
Circulation. 2023 Nov 29. doi: 10.1161/CIRCULATIONAHA.123.065458. Online ahead of print Epub:
Not Epub Abstract:
Background: A better understanding of the molecular mechanism of aortic valve development and bicuspid aortic valve (BAV)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin Y, Yang Q, Lin X, Liu X, Qian Y, Xu D, Cao N, Han X, Zhu Y, Hu W, He X, Yu Z, Kong X, Zhu L, Zhong Z, Liu K, Zhou B, Wang Y, Peng J, Zhu W, Wang J. Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation. Circulation. 2023 Nov 29. doi: 10.1161/CIRCULATIONAHA.123.065458. Online ahead of print. |
Biallelic COQ4 Variants in Hereditary Spastic Paraplegia: Clinical and Molecular Characterization
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Citation:
Mov Disord. 2023 Nov 28. doi: 10.1002/mds.29664. Online ahead of print Epub:
Not Epub Abstract:
Background: Hereditary spastic paraplegias (HSP) are neurologic disorders characterized by progressive lower-extremity... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lin X, Jiang JY, Hong DJ, Lin KJ, Li JJ, Chen YJ, Qiu YS, Wang Z, Liao YC, Yang K, Shi Y, Wang MW, Hsu SL, Hong S, Zeng YH, Chen XC, Wang N, Lee YC, Chen WJ. Biallelic COQ4 Variants in Hereditary Spastic Paraplegia: Clinical and Molecular Characterization. Mov Disord. 2023 Nov 28. doi: 10.1002/mds.29664. Online ahead of print. |
ASS1 deficiency is associated with impaired neuronal differentiation in zebrafish larvae
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Citation:
Mol Genet Metab. 2023;108097:[Epub] doi:10.1016/j.ymgme.2023.108097 Epub:
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Citrullinemia type 1 (CTLN1) is a rare autosomal recessive urea cycle disorder caused by deficiency of the cytosolic enzyme... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Seidl MJ, Scharre S, Posset R, Druck A-C, Epp F, Okun JG, Dimitrov B, Hoffmann GF, Kölker S, Zielonka M. ASS1 deficiency is associated with impaired neuronal differentiation in zebrafish larvae. Mol Genet Metab. 2023;108097:[Epub] doi:10.1016/j.ymgme.2023.108097. |
Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2
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Citation:
Sci Adv. 2023 Nov 24;9(47):eadh9673. doi: 10.1126/sciadv.adh9673. Epub 2023 Nov 24 Epub:
Not Epub Abstract:
The mammalian intestine is one of the most rapidly self-renewing tissues, driven by stem cells residing at the crypt bottom.... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Colozza G, Lee H, Merenda A, Wu SS, Català-Bordes A, Radaszkiewicz TW, Jordens I, Lee JH, Bamford AD, Farnhammer F, Low TY, Maurice MM, Bryja V, Kim J, Koo BK. Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2. Sci Adv. 2023 Nov 24;9(47):eadh9673. doi: 10.1126/sciadv.adh9673. Epub 2023 Nov 24. |