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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9231 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Granulin 1 Promotes Retinal Regeneration in Zebrafish

Authors:
Tsuruma K, Saito Y, Okuyoshi H, Yamaguchi A, Shimazawa M, Goldman D, Hara H
Citation:
Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):6057-6066. doi: 10.1167/iovs.18-24828
Abstract:
Purpose: Retinal degenerative diseases can progress to severe reductions of vision. In general, the changes are permanent in...
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Tsuruma K, Saito Y, Okuyoshi H, Yamaguchi A, Shimazawa M, Goldman D, Hara H. Granulin 1 Promotes Retinal Regeneration in Zebrafish. Invest Ophthalmol Vis Sci. 2018 Dec 3;59(15):6057-6066. doi: 10.1167/iovs.18-24828.

Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish ( Danio rerio)

Authors:
Eisa-Beygi S, Benslimane FM, El-Rass S, Prabhudesai S, Abdelrasoul MKA, Simpson PM, Yalcin HC, Burrows PE, Ramchandran R
Citation:
Arterioscler Thromb Vasc Biol. 2018 Dec;38(12):2806-2818. doi: 10.1161/ATVBAHA.118.311231
Abstract:
Objective- Endothelial cells (ECs) sense and respond to flow-induced mechanical stress, in part, via microtubule-based...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Eisa-Beygi S, Benslimane FM, El-Rass S, Prabhudesai S, Abdelrasoul MKA, Simpson PM, Yalcin HC, Burrows PE, Ramchandran R. Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish ( Danio rerio). Arterioscler Thromb Vasc Biol. 2018 Dec;38(12):2806-2818. doi: 10.1161/ATVBAHA.118.311231.

Endodermal pouch-expressed dmrt2b is important for pharyngeal cartilage formation

Authors:
Li L, Mao A, Wang P, Ning G, Cao Y, Wang Q
Citation:
Biol Open. 2018 Dec 17;7(12). pii: bio035444. doi: 10.1242/bio.035444
Abstract:
Pharyngeal pouches, a series of outpocketings derived from the foregut endoderm, are essential for craniofacial skeleton...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li L, Mao A, Wang P, Ning G, Cao Y, Wang Q. Endodermal pouch-expressed dmrt2b is important for pharyngeal cartilage formation. Biol Open. 2018 Dec 17;7(12). pii: bio035444. doi: 10.1242/bio.035444.

Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos

Authors:
Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E
Citation:
Nat Commun. 2018 Dec 14;9(1):5314. doi: 10.1038/s41467-018-07732-7
Abstract:
Arteries and veins are formed independently by different types of endothelial cells (ECs). In vascular remodeling, arteries and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weijts B, Gutierrez E, Saikin SK, Ablooglu AJ, Traver D, Groisman A, Tkachenko E. Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos. Nat Commun. 2018 Dec 14;9(1):5314. doi: 10.1038/s41467-018-07732-7.

Hif-1α-Induced Expression of Il-1β Protects against Mycobacterial Infection in Zebrafish

Authors:
Ogryzko NV, Lewis A, Wilson HL, Meijer AH, Renshaw SA, Elks PM
Citation:
J Immunol. 2018 Dec 14. pii: ji1801139. doi: 10.4049/jimmunol.1801139. [Epub ahead of print]
Abstract:
Drug-resistant mycobacteria are a rising problem worldwide. There is an urgent need to understand the immune response to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ogryzko NV, Lewis A, Wilson HL, Meijer AH, Renshaw SA, Elks PM. Hif-1α-Induced Expression of Il-1β Protects against Mycobacterial Infection in Zebrafish. J Immunol. 2018 Dec 14. pii: ji1801139. doi: 10.4049/jimmunol.1801139. [Epub ahead of print].

Pathogenic copy number variants that affect gene expression contribute to genomic burden in cerebral palsy

Authors:
Corbett MA, van Eyk CL, Webber DL, Bent SJ, Newman M, Kelly Harper, Berry JG, Azmanov DN, Woodward KJ, Gardner AE, Slee J, Pérez-Jurado LA, MacLennan AH, Gecz J
Citation:
npj Genomic Med. 2018;3:33 doi:10.1038/s41525-018-0073-4
Abstract:
Cerebral palsy (CP) is the most frequent movement disorder of childhood affecting 1 in 500 live births in developed countries....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Corbett MA, van Eyk CL, Webber DL, Bent SJ, Newman M, Kelly Harper, Berry JG, Azmanov DN, Woodward KJ, Gardner AE, Slee J, Pérez-Jurado LA, MacLennan AH, Gecz J. Pathogenic copy number variants that affect gene expression contribute to genomic burden in cerebral palsy. npj Genomic Med. 2018;3:33 doi:10.1038/s41525-018-0073-4.

Alteration of the Retinoid Acid-CBP Signaling Pathway in Neural Crest Induction Contributes to Enteric Nervous System Disorder

Authors:
Li C, Hu R, Hou N, Wang Y, Wang Z, Yang T, Gu Y, He M, Shi Y, Chen J, Song W, Li T
Citation:
Front Pediatr. 2018 Dec 3;6:382. doi: 10.3389/fped.2018.00382. eCollection 2018
Abstract:
Hirschsprung Disease (HSCR) and/or hypoganglionosis are common pediatric disorders that arise from developmental deficiencies...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Li C, Hu R, Hou N, Wang Y, Wang Z, Yang T, Gu Y, He M, Shi Y, Chen J, Song W, Li T. Alteration of the Retinoid Acid-CBP Signaling Pathway in Neural Crest Induction Contributes to Enteric Nervous System Disorder. Front Pediatr. 2018 Dec 3;6:382. doi: 10.3389/fped.2018.00382. eCollection 2018.

Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis

Authors:
Tu HQ, Qin XH, Liu ZB, Song ZQ, Hu HB, Zhang YC, Chang Y, Wu M, Huang Y, Bai YF, Wang G, Han QY, Li AL, Zhou T, Liu F, Zhang XM, Li HY
Citation:
Nat Commun. 2018 Dec 11;9(1):5277. doi: 10.1038/s41467-018-07664-2
Abstract:
Defective ciliogenesis causes human developmental diseases termed ciliopathies. Microtubule (MT) asters originating from...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tu HQ, Qin XH, Liu ZB, Song ZQ, Hu HB, Zhang YC, Chang Y, Wu M, Huang Y, Bai YF, Wang G, Han QY, Li AL, Zhou T, Liu F, Zhang XM, Li HY. Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis. Nat Commun. 2018 Dec 11;9(1):5277. doi: 10.1038/s41467-018-07664-2.

Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border

Authors:
Narboux-Neme N. Ekker M, Levi G, Heude É
Citation:
bioRxiv. 2018;[Preprint] doi:10.1101/435321
Abstract:
Neural tube defects (NTDs), one of the most common birth defects in human, present a multifactorial etiology with a poorly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Narboux-Neme N. Ekker M, Levi G, Heude É. Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border. bioRxiv. 2018;[Preprint] doi:10.1101/435321.

The RhoGEF protein Plekhg5 regulates apical constriction of bottle cells during gastrulation

Authors:
Popov IK, Ray HJ, Skoglund P, Keller R, Chang C
Citation:
Development. 2018 Dec 12;145(24). pii: dev168922. doi: 10.1242/dev.168922
Abstract:
Apical constriction regulates epithelial morphogenesis during embryonic development, but how this process is controlled is not...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Popov IK, Ray HJ, Skoglund P, Keller R, Chang C. The RhoGEF protein Plekhg5 regulates apical constriction of bottle cells during gastrulation. Development. 2018 Dec 12;145(24). pii: dev168922. doi: 10.1242/dev.168922.

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