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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9231 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids

Authors:
Erkenbrack EM, Davidson EH, Peter IS
Citation:
Development. 2018 Nov 23. pii: dev.167288. doi: 10.1242/dev.167288. [Epub ahead of print]
Abstract:
Evolution of the animal body plan is driven by changes in developmental gene regulatory networks (GRNs), but how networks...
Organism or Cell Type:
Eucidaris tribuloides (sea urchin)
Citation Extract:
Erkenbrack EM, Davidson EH, Peter IS. Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids. Development. 2018 Nov 23. pii: dev.167288. doi: 10.1242/dev.167288. [Epub ahead of print].

Induction of Interferon-Stimulated Genes and Cellular Stress Pathways by Morpholinos

Authors:
Lai JKH, Gagalova K, Stainier DYR
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/479188
Abstract:
The phenotypes caused by morpholino-mediated interference of gene function in zebrafish are often not observed in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lai JKH, Gagalova K, Stainier DYR. Induction of Interferon-Stimulated Genes and Cellular Stress Pathways by Morpholinos. bioRxive. 2018;[Preprint] doi:10.1101/479188.

Centrosomal protein FOR20 is essential for cilia-dependent development in zebrafish embryos

Authors:
Xie S, Jin J, Xu Z, Huang Y, Zhang W, Zhao L, Lo LJ, Peng J, Liu W, Wang F, Shu Q, Zhou T
Citation:
FASEB J. 2018 Nov 26:fj201801235RR. doi: 10.1096/fj.201801235RR. [Epub ahead of print]
Abstract:
Centrosomal proteins play critical roles in ciliogenesis. Mutations in many centrosomal proteins have been documented to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xie S, Jin J, Xu Z, Huang Y, Zhang W, Zhao L, Lo LJ, Peng J, Liu W, Wang F, Shu Q, Zhou T. Centrosomal protein FOR20 is essential for cilia-dependent development in zebrafish embryos. FASEB J. 2018 Nov 26:fj201801235RR. doi: 10.1096/fj.201801235RR. [Epub ahead of print].

Knockdown of calcium-binding calb2a and calb2b genes indicates the key regulator of the early development of the zebrafish, Danio rerio

Authors:
Bhoyar RC, Jadhao AG, Sabharwal A, Ranjan G, Sivasubbu S, Pinelli C
Citation:
Brain Struct Funct. 2018 Nov 20. doi: 10.1007/s00429-018-1797-8. [Epub ahead of print]
Abstract:
The present study initiates our investigation regarding the role of calb2a and calb2b genes that are expressed in the central...
Organism or Cell Type:
zebrafish
Citation Extract:
Bhoyar RC, Jadhao AG, Sabharwal A, Ranjan G, Sivasubbu S, Pinelli C. Knockdown of calcium-binding calb2a and calb2b genes indicates the key regulator of the early development of the zebrafish, Danio rerio. Brain Struct Funct. 2018 Nov 20. doi: 10.1007/s00429-018-1797-8. [Epub ahead of print].

Drug-free albumin-triggered sensitization of cancer cells to anticancer drugs

Authors:
Li L, Yang J, Soodvilai S, Wang J, Opanasopit P, Kopeček J
Citation:
J Control Release. 2018;[Epub ahead of print] doi:10.1016/j.jconrel.2018.11.015
Abstract:
Chemosensitization strategies have been used to sensitize cancer cells to conventional drugs, but their utility is often...
Citation Extract:
Li L, Yang J, Soodvilai S, Wang J, Opanasopit P, Kopeček J. Drug-free albumin-triggered sensitization of cancer cells to anticancer drugs. J Control Release. 2018;[Epub ahead of print] doi:10.1016/j.jconrel.2018.11.015.

Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing

Authors:
Blazquez L, Emmett W, Faraway R, Pineda JMB, Bajew S, Gohr A, Haberman N, Sibley CR, Bradley RK, Irimia M, Ule J
Citation:
Mol Cell. 2018 Nov 1;72(3):496-509.e9. doi: 10.1016/j.molcel.2018.09.033
Abstract:
Recursive splicing (RS) starts by defining an "RS-exon," which is then spliced to the preceding exon, thus creating a...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HeLa Flp-In T-REx KPNA1, mouse neural precursos cells (NPC)
Citation Extract:
Blazquez L, Emmett W, Faraway R, Pineda JMB, Bajew S, Gohr A, Haberman N, Sibley CR, Bradley RK, Irimia M, Ule J. Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing. Mol Cell. 2018 Nov 1;72(3):496-509.e9. doi: 10.1016/j.molcel.2018.09.033.

Zebrafish miR-462-731 regulates hematopoietic specification and pu.1-dependent primitive myelopoiesis

Authors:
Huang C-X, Huang Y, Duan X-K, Zhang M, Tu J-P, Liu J-X, Liu H, Chen T-S, Wang W-M, Wang H-L.
Citation:
Cell Death Differ. 2018; doi:10.1038/s41418-018-0234-0
Abstract:
MicroRNAs (miRNAs) play significant roles in both embryonic hematopoiesis and hematological malignancy. Zebrafish miR-462-731...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang C-X, Huang Y, Duan X-K, Zhang M, Tu J-P, Liu J-X, Liu H, Chen T-S, Wang W-M, Wang H-L.. Zebrafish miR-462-731 regulates hematopoietic specification and pu.1-dependent primitive myelopoiesis. Cell Death Differ. 2018; doi:10.1038/s41418-018-0234-0.

VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche

Authors:
Li D, Xue W, Li M, Dong M, Wang J, Wang X, Li X, Chen K, Zhang W, Wu S, Zhang Y, Gao L, Chen Y, Chen J, Zhou BO, Zhou Y, Yao X, Li L, Wu D, Pan W
Citation:
Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0709-7
Abstract:
Haematopoietic stem and progenitor cells (HSPCs) give rise to all blood lineages that support the entire lifespan of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li D, Xue W, Li M, Dong M, Wang J, Wang X, Li X, Chen K, Zhang W, Wu S, Zhang Y, Gao L, Chen Y, Chen J, Zhou BO, Zhou Y, Yao X, Li L, Wu D, Pan W. VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche. Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0709-7.

Targeted exon skipping of a CEP290 mutation rescues Joubert syndrome phenotypes in vitro and in a murine model

Authors:
Ramsbottom SA, Molinari E, Srivastava S, Silberman F, Henry C, Alkanderi S, Devlin LA, White K, Steel DH, Saunier S, Miles CG, Sayer JA
Citation:
Proc Natl Acad Sci U S A. 2018 Nov 16. pii: 201809432. doi: 10.1073/pnas.1809432115. [Epub ahead of print]
Abstract:
Genetic treatments of renal ciliopathies leading to cystic kidney disease would provide a real advance in current therapies....
Delivery Method:
Endo-Porter, Vivo-Morpholino
Organism or Cell Type:
cell culture: human urine-derived renal epithelial kidney cells (hURECs), Cep290Gt mice
Citation Extract:
Ramsbottom SA, Molinari E, Srivastava S, Silberman F, Henry C, Alkanderi S, Devlin LA, White K, Steel DH, Saunier S, Miles CG, Sayer JA. Targeted exon skipping of a CEP290 mutation rescues Joubert syndrome phenotypes in vitro and in a murine model. Proc Natl Acad Sci U S A. 2018 Nov 16. pii: 201809432. doi: 10.1073/pnas.1809432115. [Epub ahead of print].

Lin CY, Zhang PH, Chen YJ, Wu CL, Tsai HJ

Authors:
Conditional Overexpression of rtn4al in Muscle of Adult Zebrafish Displays Defects Similar to Human Amyotrophic Lateral Sclerosis
Citation:
Mar Biotechnol (NY). 2018 Nov 15. doi: 10.1007/s10126-018-9857-x. [Epub ahead of print]
Abstract:
The protein level of muscle-specific human NogoA is abnormally upregulated in amyotrophic lateral sclerosis (ALS) mice and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Conditional Overexpression of rtn4al in Muscle of Adult Zebrafish Displays Defects Similar to Human Amyotrophic Lateral Sclerosis. Lin CY, Zhang PH, Chen YJ, Wu CL, Tsai HJ. Mar Biotechnol (NY). 2018 Nov 15. doi: 10.1007/s10126-018-9857-x. [Epub ahead of print].

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