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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen

Authors:
Peal DS, Mills RW, Lynch SN, Mosley JM, Lim E, Ellinor PT, January CT, Peterson RT, Milan DJ
Citation:
Circulation. 2011 Jan 4;123(1):23-30. Epub 2010 Nov 15.
Epub:
Not Epub
Abstract:
Background- Genetic long QT (LQT) syndrome is a life-threatening disorder caused by mutations that result in prolongation of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peal DS, Mills RW, Lynch SN, Mosley JM, Lim E, Ellinor PT, January CT, Peterson RT, Milan DJ. Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen. Circulation. 2011 Jan 4;123(1):23-30. Epub 2010 Nov 15..

Novel gene ashwin functions in Xenopus cell survival and anteroposterior patterning

Authors:
Patil SS, Alexander TB, Uzman JA, Lou CH, Gohil H, Sater AK
Citation:
Dev Dyn. 2006 May 5;235(7):1895-1907 [Epub ahead of print]
Epub:
Not Epub
Abstract:
The novel gene ashwin was isolated in a differential display screen for genes activated or up-regulated early in neural...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Patil SS, Alexander TB, Uzman JA, Lou CH, Gohil H, Sater AK. Novel gene ashwin functions in Xenopus cell survival and anteroposterior patterning. Dev Dyn. 2006 May 5;235(7):1895-1907 [Epub ahead of print].

Oligodendrocyte specification in zebrafish requires notch-regulated cyclin-dependent kinase inhibitor function

Authors:
Park HC, Boyce J, Shin J, Appel B
Citation:
J Neurosci. 2005 Jul 20;25(29):6836-44
Epub:
Not Epub
Abstract:
Cyclin-dependent kinase inhibitors (Cdkis) influence both cell-cycle progression and differentiation of neural cells. However,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Park HC, Boyce J, Shin J, Appel B. Oligodendrocyte specification in zebrafish requires notch-regulated cyclin-dependent kinase inhibitor function. J Neurosci. 2005 Jul 20;25(29):6836-44.

p38α MAPK is a MTOC-associated protein regulating spindle assembly, spindle length and accurate chromosome segregation during mouse oocyte meiotic maturation

Authors:
Ou XH, Li S, Xu BZ, Wang ZB, Quan S, Li M, Zhang QH, Ouyang YC, Schatten H, Xing FQ, Sun QY
Citation:
Cell Cycle. 2010 Oct 20;9(20). [Epub ahead of print]
Epub:
Not Epub
Abstract:
P38αMAPK (p38α) is usually activated in response to various stresses and plays a role in the inhibition of cell proliferation...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Ou XH, Li S, Xu BZ, Wang ZB, Quan S, Li M, Zhang QH, Ouyang YC, Schatten H, Xing FQ, Sun QY. p38α MAPK is a MTOC-associated protein regulating spindle assembly, spindle length and accurate chromosome segregation during mouse oocyte meiotic maturation. Cell Cycle. 2010 Oct 20;9(20). [Epub ahead of print].

PAR-1 phosphorylates Mind bomb to promote vertebrate neurogenesis

Authors:
Ossipova O, Ezan J, Sokol SY
Citation:
Dev Cell. 2009 Aug;17(2):222-33
Epub:
Not Epub
Abstract:
Generation of neurons in the vertebrate central nervous system requires a complex transcriptional regulatory network and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ossipova O, Ezan J, Sokol SY. PAR-1 phosphorylates Mind bomb to promote vertebrate neurogenesis. Dev Cell. 2009 Aug;17(2):222-33.

PAR1 specifies ciliated cells in vertebrate ectoderm downstream of aPKC

Authors:
Ossipova O, Tabler J, Green JB, Sokol SY
Citation:
Development. 2007 Dec;134(23):4297-306
Epub:
Not Epub
Abstract:
Partitioning-defective 1 (PAR1) and atypical protein kinase C (aPKC) are conserved serine/threonine protein kinases implicated...
Organism or Cell Type:
Xenopus
Citation Extract:
Ossipova O, Tabler J, Green JB, Sokol SY. PAR1 specifies ciliated cells in vertebrate ectoderm downstream of aPKC. Development. 2007 Dec;134(23):4297-306.

Pax2/8 proteins coordinate sequential induction of otic and epibranchial placodes through differential regulation of foxi1, sox3 and fgf24

Authors:
Padanad MS, Riley BB
Citation:
Dev Biol. 2011 Mar 1;351(1):90-8. Epub 2011 Jan 4
Epub:
Not Epub
Abstract:
Vertebrate cranial placodes contribute vitally to development of sensory structures of the head. Amongst posterior placodes,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Padanad MS, Riley BB. Pax2/8 proteins coordinate sequential induction of otic and epibranchial placodes through differential regulation of foxi1, sox3 and fgf24. Dev Biol. 2011 Mar 1;351(1):90-8. Epub 2011 Jan 4.

Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis

Authors:
Panchal RG, Geller BL, Mellbye B, Lane D, Iversen PL, Bavari S
Citation:
Nucleic Acid Therapeutics. 2012;[Epub ahead of print] doi:10.1089/nat.2012.0362
Epub:
Not Epub
Abstract:
Targeting bacterial essential genes using antisense phosphorodiamidate morpholino oligomers (PMOs) represents an important...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Bacillus anthracis
Citation Extract:
Panchal RG, Geller BL, Mellbye B, Lane D, Iversen PL, Bavari S. Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis. Nucleic Acid Therapeutics. 2012;[Epub ahead of print] doi:10.1089/nat.2012.0362.

Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication

Authors:
Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ
Citation:
Antiviral Res. 2008 Feb;77(2):95-107. Epub 2007 Oct 4
Epub:
Not Epub
Abstract:
Porcine reproductive and respiratory syndrome (PRRS) has been devastating the global swine industry for more than a decade, and...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Porcine reproductive and resporatory syndrome virus (PRRSV) in cell cultures
Citation Extract:
Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ. Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication. Antiviral Res. 2008 Feb;77(2):95-107. Epub 2007 Oct 4.

Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes

Authors:
Pascreau G, Eckerdt F, Lewellyn AL, Prigent C, Maller JL
Citation:
J Biol Chem. 2009 Feb 27;284(9):5497-505. Epub 2009 Jan 2
Epub:
Not Epub
Abstract:
p53 is an important tumor suppressor regulating the cell cycle at multiple stages in higher vertebrates. The p53 gene is...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pascreau G, Eckerdt F, Lewellyn AL, Prigent C, Maller JL. Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes. J Biol Chem. 2009 Feb 27;284(9):5497-505. Epub 2009 Jan 2.

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