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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

HIF-1alpha signaling upstream of Nkx2.5 is required for cardiac development in xenopus

Authors:
Nagao K, Taniyama Y, Kietzmann T, Doi T, Komuro I, Morishita R
Citation:
J Biol Chem. 2008 Apr 25;283(17):11841-9. Epub 2008 Feb 25.
Epub:
Not Epub
Abstract:
HIF-1alpha is originally identified as a transcription factor that activates gene expression in response to hypoxia. In...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Nagao K, Taniyama Y, Kietzmann T, Doi T, Komuro I, Morishita R. HIF-1alpha signaling upstream of Nkx2.5 is required for cardiac development in xenopus. J Biol Chem. 2008 Apr 25;283(17):11841-9. Epub 2008 Feb 25..

Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors

Authors:
Nejigane S, Takahashi S, Haramoto Y, Michiue T, Asashima M
Citation:
Int J Dev Biol. 2013;57(5):407-14. doi: 10.1387/ijdb.130010st.
Epub:
Not Epub
Abstract:
Hippo signaling is a conserved pathway that regulates cell proliferation and organ size control. Mst1 and Mst2 were identified...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Nejigane S, Takahashi S, Haramoto Y, Michiue T, Asashima M. Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors. Int J Dev Biol. 2013;57(5):407-14. doi: 10.1387/ijdb.130010st..

Identification and angiogenic role of the novel tumor endothelial marker CLEC14A

Authors:
Mura M, Swain RK, Zhuang X, Vorschmitt H, Reynolds G, Durant S, Beesley JF, Herbert JM, Sheldon H, Andre M, Sanderson S, Glen K, Luu NT, McGettrick HM, Antczak P, Falciani F, Nash GB, Nagy ZS, Bicknell R
Citation:
Oncogene. 2012 Jan 19;31(3):293-305. doi: 10.1038/onc.2011.233. Epub 2011 Jun 27
Epub:
Not Epub
Abstract:
Tumor endothelial markers (TEMs) that are highly expressed in human tumor vasculature compared with vasculature in normal...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mura M, Swain RK, Zhuang X, Vorschmitt H, Reynolds G, Durant S, Beesley JF, Herbert JM, Sheldon H, Andre M, Sanderson S, Glen K, Luu NT, McGettrick HM, Antczak P, Falciani F, Nash GB, Nagy ZS, Bicknell R. Identification and angiogenic role of the novel tumor endothelial marker CLEC14A. Oncogene. 2012 Jan 19;31(3):293-305. doi: 10.1038/onc.2011.233. Epub 2011 Jun 27.

Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates

Authors:
Muto E, Tabata Y, Taneda T, Aoki Y, Muto A, Arai K, Watanabe S
Citation:
Biochimie. 2004 Aug;86(8):523-31
Epub:
Not Epub
Abstract:
We isolated Veph, a novel gene encoding a pleckstrin homology (PH) domain-containing protein from a mouse. Veph was strongly...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Muto E, Tabata Y, Taneda T, Aoki Y, Muto A, Arai K, Watanabe S. Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates. Biochimie. 2004 Aug;86(8):523-31.

In vitro oocyte culture-based manipulation of zebrafish maternal genes

Authors:
Nair S, Lindeman RE, Pelegri F
Citation:
Dev Dyn. 2012 Oct 16. doi: 10.1002/dvdy.23894. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In animals, females deposit gene products into developing oocytes, which drive early cellular events in embryos immediately...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nair S, Lindeman RE, Pelegri F. In vitro oocyte culture-based manipulation of zebrafish maternal genes. Dev Dyn. 2012 Oct 16. doi: 10.1002/dvdy.23894. [Epub ahead of print].

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Authors:
Niederriter AR, Davis EE, Golzio C, Oh EC, Tsai IC, Katsanis N
Citation:
J Vis Exp. 2013;(78):e50338. doi:10.3791/50338
Epub:
Not Epub
Abstract:
Here, we present methods for the development of assays to query potentially clinically significant nonsynonymous changes using...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Niederriter AR, Davis EE, Golzio C, Oh EC, Tsai IC, Katsanis N. In Vivo Modeling of the Morbid Human Genome using Danio rerio. J Vis Exp. 2013;(78):e50338. doi:10.3791/50338.

Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryo

Authors:
Nakano Y, Kim HR, Kawakami A, Roy S, Schier AF, Ingham PW
Citation:
Dev Biol. 2004 May 15;269(2):381-92
Epub:
Not Epub
Abstract:
Searches of zebrafish EST and whole genome shotgun sequence databases for sequences encoding the sterol-sensing domain (SSD)...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nakano Y, Kim HR, Kawakami A, Roy S, Schier AF, Ingham PW. Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryo. Dev Biol. 2004 May 15;269(2):381-92.

Inhibiting Uterine PC6 Blocks Embryo Implantation: An Obligatory Role for a Proprotein Convertase in Fertility

Authors:
Nie G, Li Y, Wang M, Liu YX, Findlay JK, Salamonsen LA
Citation:
Biol Reprod. 2005 Apr;72(4):1029-36. Epub 2004 Dec 15.
Epub:
Not Epub
Abstract:
Successful embryo implantation involves complex interactions between the embryo and the uterus and is critical in establishing...
Delivery Method:
in vivo: uterine (Special Delivery)
Organism or Cell Type:
mice
Citation Extract:
Nie G, Li Y, Wang M, Liu YX, Findlay JK, Salamonsen LA. Inhibiting Uterine PC6 Blocks Embryo Implantation: An Obligatory Role for a Proprotein Convertase in Fertility. Biol Reprod. 2005 Apr;72(4):1029-36. Epub 2004 Dec 15..

Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers

Authors:
Neuman BW, Stein DA, Kroeker AD, Moulton HM, Bestwick RK, Iversen PL, Buchmeier MJ
Citation:
Adv Exp Med Biol. 2006;581:567-71
Epub:
Not Epub
Abstract:
Identification of potential SARS-CoV antiviral compounds has progressed swiftly, thanks in part to the availability of...
Citation Extract:
Neuman BW, Stein DA, Kroeker AD, Moulton HM, Bestwick RK, Iversen PL, Buchmeier MJ. Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers. Adv Exp Med Biol. 2006;581:567-71.

Inhibition of KSHV-associated lymphoma engraftment in SCID mouse by morpholino oligomers

Authors:
Nan Y, Patel D, Zhang Y
Citation:
Infect Agent Cancer. 2010; 5(Suppl 1): A40. Epub 2010 Oct 11
Epub:
Not Epub
Abstract:
Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, is associated with several malignant...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mouse, SCID
Citation Extract:
Nan Y, Patel D, Zhang Y. Inhibition of KSHV-associated lymphoma engraftment in SCID mouse by morpholino oligomers. Infect Agent Cancer. 2010; 5(Suppl 1): A40. Epub 2010 Oct 11.

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