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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Functional specificity of the Xenopus T-domain protein brachyury is conferred by its ability to interact with smad1

Authors:
Messenger NJ, Kabitschke C, Andrews R, Grimmer D, Miguel RN, Blundell TL, Smith JC, Wardle FC
Citation:
Dev Cell. 2005 Apr;8(4):599-610
Epub:
Not Epub
Abstract:
Members of the T-box gene family play important and diverse roles in development and disease. Here, we study the functional...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Messenger NJ, Kabitschke C, Andrews R, Grimmer D, Miguel RN, Blundell TL, Smith JC, Wardle FC. Functional specificity of the Xenopus T-domain protein brachyury is conferred by its ability to interact with smad1. Dev Cell. 2005 Apr;8(4):599-610.

Geminin Deficiency Causes a Chk1-dependent G2 Arrest in Xenopus

Authors:
McGarry TJ
Citation:
Mol Biol Cell. 2002 Oct 1; 13(10): 3662-3671
Epub:
Not Epub
Abstract:
Geminin is an unstable inhibitor of DNA replication that gets destroyed at the metaphase/anaphase transition. The biological...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
McGarry TJ. Geminin Deficiency Causes a Chk1-dependent G2 Arrest in Xenopus. Mol Biol Cell. 2002 Oct 1; 13(10): 3662-3671.

Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model

Authors:
McIntyre JC, Davis E, Joiner A, Williams CL, Tsai IC, Jenkins PM, McEwen DP, Zhang L, Escobado J, Thomas S, Szymanska K, Johnson CA, Beales PL, Green ED, Mullikin JC, NISC Comparative Sequencing Program, Sabo A, Muzny DM, Gibbs RA, Attie-Bitach T, Yoder BK, Reed RR, Katsanis N, Martens J
Citation:
Nat Med. 2012;[Epub ahead of print] doi:/10.1038/nm.2860
Epub:
Not Epub
Abstract:
Cilia are evolutionarily conserved microtubule-based organelles that are crucial for diverse biological functions, including...
Organism or Cell Type:
zebrafish
Citation Extract:
McIntyre JC, Davis E, Joiner A, Williams CL, Tsai IC, Jenkins PM, McEwen DP, Zhang L, Escobado J, Thomas S, Szymanska K, Johnson CA, Beales PL, Green ED, Mullikin JC, NISC Comparative Sequencing Program, Sabo A, Muzny DM, Gibbs RA, Attie-Bitach T, Yoder BK, Reed RR, Katsanis N, Martens J . Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model. Nat Med. 2012;[Epub ahead of print] doi:/10.1038/nm.2860.

Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent

Authors:
Mich JK, Blaser H, Thomas NA, Firestone AJ, Yelon D, Raz E, Chen JK
Citation:
Dev Biol. 2009 Apr 15;328(2):342-54. Epub 2009 Feb 4
Epub:
Not Epub
Abstract:
Primordial germ cells (PGCs) are the progenitors of reproductive cells in metazoans and are an important model for the study of...
Delivery Method:
Microinjection
Organism or Cell Type:
Zebrafish (lit. review)
Citation Extract:
Mich JK, Blaser H, Thomas NA, Firestone AJ, Yelon D, Raz E, Chen JK. Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent. Dev Biol. 2009 Apr 15;328(2):342-54. Epub 2009 Feb 4.

Glucosylceramide transferase activity is critical for encystation and viable cyst production by an intestinal protozoan, Giardia lamblia

Authors:
Mendez TL, Chatterjee AD, Duarte TT, Gazos-Lopes F, Robles-Martinez L, Roy D, Sun J, Maldonado RA, Roychowdhury S, Almeida IC, Das S
Citation:
J Biol Chem. 2013;[Epub ahead of print] doi:10.1074/jbc.M112.438416
Epub:
Not Epub
Abstract:
The production of viable cysts by Giardia is essential for its survival in the environment and spreading the infection via...
Delivery Method:
Electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Mendez TL, Chatterjee AD, Duarte TT, Gazos-Lopes F, Robles-Martinez L, Roy D, Sun J, Maldonado RA, Roychowdhury S, Almeida IC, Das S. Glucosylceramide transferase activity is critical for encystation and viable cyst production by an intestinal protozoan, Giardia lamblia. J Biol Chem. 2013;[Epub ahead of print] doi:10.1074/jbc.M112.438416 .

Glycine receptors regulate interneuron differentiation during spinal network development

Authors:
McDearmid JR, Liao M, Drapeau P
Citation:
Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9679-84. Epub 2006 Jun 8
Epub:
Not Epub
Abstract:
Glycinergic and GABAergic excitatory chloride-mediated signaling is often the first form of activity to emerge in the nascent...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McDearmid JR, Liao M, Drapeau P. Glycine receptors regulate interneuron differentiation during spinal network development. Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9679-84. Epub 2006 Jun 8.

Graded levels of Pax2a and Pax8 regulate cell differentiation during sensory placode formation

Authors:
McCarroll MN, Lewis ZR, Culbertson MD, Martin BL, Kimelman D, Nechiporuk AV
Citation:
Development. 2012 Aug;139(15):2740-50. doi: 10.1242/dev.076075. Epub 2012 Jun 28
Epub:
Not Epub
Abstract:
Pax gene haploinsufficiency causes a variety of congenital defects. Renal-coloboma syndrome, resulting from mutations in Pax2,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McCarroll MN, Lewis ZR, Culbertson MD, Martin BL, Kimelman D, Nechiporuk AV. Graded levels of Pax2a and Pax8 regulate cell differentiation during sensory placode formation. Development. 2012 Aug;139(15):2740-50. doi: 10.1242/dev.076075. Epub 2012 Jun 28.

Growth differentiation factor-9 signaling in the ovary

Authors:
Mazerbourg S, Hsueh AJ
Citation:
Mol Cell Endocrinol. 2003 Apr 28;202(1-2):31-6
Epub:
Not Epub
Abstract:
Growth differentiation factor-9 (GDF-9) is an oocyte-derived growth factor and a member of the transforming growth factor-beta...
Delivery Method:
not published
Organism or Cell Type:
Mouse embryo
Citation Extract:
Mazerbourg S, Hsueh AJ. Growth differentiation factor-9 signaling in the ovary. Mol Cell Endocrinol. 2003 Apr 28;202(1-2):31-6.

Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins

Authors:
Milanese C, Sager JJ, Bai Q, Farrell TC, Cannon JR, Greenamyre JT, Burton EA
Citation:
J Biol Chem. 2012 Jan 27;287(5):2971-83. doi: 10.1074/jbc.M111.308312. Epub 2011 Nov 29
Epub:
Not Epub
Abstract:
α-Synuclein is strongly implicated in the pathogenesis of Parkinson disease. However, the normal functions of synucleins and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Milanese C, Sager JJ, Bai Q, Farrell TC, Cannon JR, Greenamyre JT, Burton EA. Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins. J Biol Chem. 2012 Jan 27;287(5):2971-83. doi: 10.1074/jbc.M111.308312. Epub 2011 Nov 29.

Identification of chaperonin CCTgamma subunit as a determinant of retinotectal development by whole-genome subtraction cloning from zebrafish no tectal neuron mutant

Authors:
Matsuda N, Mishina M
Citation:
Development. 2004 May;131(9):1913-25.
Epub:
Not Epub
Abstract:
Zebrafish no tectal neuron (ntn) mutant obtained by trimethylpsoralen (TMP) mutagenesis showed defects in tectal neuropil...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Matsuda N, Mishina M. Identification of chaperonin CCTgamma subunit as a determinant of retinotectal development by whole-genome subtraction cloning from zebrafish no tectal neuron mutant. Development. 2004 May;131(9):1913-25..

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