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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12067 scientific papers returned from the database with the search filters currently being used below.

DeltaA/DeltaD Regulate Multiple and Temporally Distinct Phases of Notch Signaling during Dopaminergic Neurogenesis in Zebrafish

Authors:
Mahler J, Filippi A, Driever W
Citation:
J Neurosci. 2010 Dec 8;30(49):16621-35; doi:10.1523/JNEUROSCI.4769-10.2010
Epub:
Not Epub
Abstract:
Dopaminergic neurons develop at distinct anatomical sites to form some of the major neuromodulatory systems in the vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mahler J, Filippi A, Driever W. DeltaA/DeltaD Regulate Multiple and Temporally Distinct Phases of Notch Signaling during Dopaminergic Neurogenesis in Zebrafish. J Neurosci. 2010 Dec 8;30(49):16621-35; doi:10.1523/JNEUROSCI.4769-10.2010.

Dishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarity

Authors:
Mahuzier A, Gaudé HM, Grampa V, Anselme I, Silbermann F, Leroux-Berger M, Delacour D, Ezan J, Montcouquiol M, Saunier S, Schneider-Maunoury S, Vesque C
Citation:
J Cell Biol. 2012 Aug 27. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cilia are at the core of planar polarity cellular events in many systems. However, the molecular mechanisms by which they...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mahuzier A, Gaudé HM, Grampa V, Anselme I, Silbermann F, Leroux-Berger M, Delacour D, Ezan J, Montcouquiol M, Saunier S, Schneider-Maunoury S, Vesque C. Dishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarity. J Cell Biol. 2012 Aug 27. [Epub ahead of print].

Dishevelled2 Is a Stable Protein During Early Zebrafish Development

Authors:
Lum WM, Robertson JK, Van Raay TJ
Citation:
Zebrafish. 2011 [Epub ahead of print] doi:10.1089/zeb.2011.0691
Epub:
Not Epub
Abstract:
Wnt signaling is a major player during development and its misregulation often leads to disease, especially cancer. The...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lum WM, Robertson JK, Van Raay TJ. Dishevelled2 Is a Stable Protein During Early Zebrafish Development. Zebrafish. 2011 [Epub ahead of print] doi:10.1089/zeb.2011.0691.

Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway

Authors:
Luxardi G, Marchal L, Thomé V, Kodjabachian L
Citation:
Development. 2010 Jan 7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The vertebrate body plan is established in two major steps. First, mesendoderm induction singles out prospective endoderm,...
Organism or Cell Type:
Xenopus
Citation Extract:
Luxardi G, Marchal L, Thomé V, Kodjabachian L. Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway. Development. 2010 Jan 7. [Epub ahead of print].

Dominant mutation of CCDC78 in a unique congenital myopathy with prominent internal nuclei and atypical cores

Authors:
Majczenko K, Davidson AE, Camelo-Piragua S, Agrawal PB, Manfready RA, Li X, Joshi S, Xu J, Peng W, Beggs AH, Li JZ, Burmeister M, Dowling JJ
Citation:
Am J Hum Genet. 2012 Aug 10;91(2):365-71. doi: 10.1016/j.ajhg.2012.06.012. Epub 2012 Jul 19
Epub:
Not Epub
Abstract:
Congenital myopathies are clinically and genetically heterogeneous diseases that typically present in childhood with hypotonia...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Majczenko K, Davidson AE, Camelo-Piragua S, Agrawal PB, Manfready RA, Li X, Joshi S, Xu J, Peng W, Beggs AH, Li JZ, Burmeister M, Dowling JJ. Dominant mutation of CCDC78 in a unique congenital myopathy with prominent internal nuclei and atypical cores. Am J Hum Genet. 2012 Aug 10;91(2):365-71. doi: 10.1016/j.ajhg.2012.06.012. Epub 2012 Jul 19.

Dosing regimen has a significant impact on the efficiency of morpholino oligomer-induced exon skipping in mdx mice

Authors:
Malerba A, Thorogood FC, Dickson G, Graham IR
Citation:
Hum Gene Ther. 2009 Sep;20(9):955-65.
Epub:
Not Epub
Abstract:
Duchenne Muscular Dystrophy (DMD) is a myodegenerative disorder caused primarily by mutations that create premature termination...
Delivery Method:
in vivo: injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Malerba A, Thorogood FC, Dickson G, Graham IR. Dosing regimen has a significant impact on the efficiency of morpholino oligomer-induced exon skipping in mdx mice. Hum Gene Ther. 2009 Sep;20(9):955-65..

DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1

Authors:
Ly A, Nikolaev A, Suresh G, Zheng Y, Tessier-Lavigne M, Stein E
Citation:
Cell. 2008 Jun 27;133(7):1241-54
Epub:
Not Epub
Abstract:
During nervous system development, spinal commissural axons project toward and across the ventral midline. They are guided in...
Organism or Cell Type:
Xenopus
Citation Extract:
Ly A, Nikolaev A, Suresh G, Zheng Y, Tessier-Lavigne M, Stein E. DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1. Cell. 2008 Jun 27;133(7):1241-54.

Dual Myostatin and Dystrophin Exon Skipping by Morpholino Nucleic Acid Oligomers Conjugated to a Cell-penetrating Peptide Is a Promising Therapeutic Strategy for the Treatment of Duchenne Muscular Dystrophy

Authors:
Malerba A, Kang JK, McClorey G, Saleh AF, Popplewell L, Gait MJ, Wood MJA, Dickson G
Citation:
Mol Ther Nucleic Acids. 2012;1:e62. doi:/10.1038/mtna.2012.54
Epub:
Not Epub
Abstract:
The knockdown of myostatin, a negative regulator of skeletal muscle mass may have important implications in disease conditions...
Delivery Method:
Vivo-Morpholino oligos and peptide coupled oligos
Organism or Cell Type:
mice, mdx and normal
Citation Extract:
Malerba A, Kang JK, McClorey G, Saleh AF, Popplewell L, Gait MJ, Wood MJA, Dickson G. Dual Myostatin and Dystrophin Exon Skipping by Morpholino Nucleic Acid Oligomers Conjugated to a Cell-penetrating Peptide Is a Promising Therapeutic Strategy for the Treatment of Duchenne Muscular Dystrophy. Mol Ther Nucleic Acids. 2012;1:e62. doi:/10.1038/mtna.2012.54.

Dystroglycan is required for proper retinal layering

Authors:
Lunardi A, Cremisi F, Dente L
Citation:
Dev Biol. 2006 Feb 15;290(2):411-20. Epub 2006 Jan 9.
Epub:
Not Epub
Abstract:
Dystroglycan (DG) is a transmembrane receptor linking the extracellular matrix to the internal cytoskeleton. Its structural...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lunardi A, Cremisi F, Dente L. Dystroglycan is required for proper retinal layering. Dev Biol. 2006 Feb 15;290(2):411-20. Epub 2006 Jan 9..

Eafs Control Erythroid Cell Fate by Regulating c-myb Expression through Wnt Signaling

Authors:
Ma X, Liu J-X
Citation:
PLoS ONE 2013;8(5):e64576. doi:10.1371/journal.pone.0064576
Epub:
Not Epub
Abstract:
ELL associated factor 1 and ELL associated factor 2 (EAF1/2 factors) are reported to play important roles in tumor suppression...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma X, Liu J-X. Eafs Control Erythroid Cell Fate by Regulating c-myb Expression through Wnt Signaling. PLoS ONE 2013;8(5):e64576. doi:10.1371/journal.pone.0064576.

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