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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Killing the messenger: The role of CXCR7 in regulating primordial germ cell migration

Authors:
Mahabaleshwar H, Boldajipour B, Raz E
Citation:
Cell Adh Migr. 2008 Apr;2(2):69-70. Epub 2008 Apr 3
Epub:
Not Epub
Abstract:
Primordial Germ Cell (PGC) migration in zebrafish is guided by SDF-1a. Binding of this chemokine to its receptor CXCR4b...
Organism or Cell Type:
zebrafish
Citation Extract:
Mahabaleshwar H, Boldajipour B, Raz E. Killing the messenger: The role of CXCR7 in regulating primordial germ cell migration. Cell Adh Migr. 2008 Apr;2(2):69-70. Epub 2008 Apr 3.

Laser-scanning velocimetry: A confocal microscopy method for quantitative measurement of cardiovascular performance in zebrafish embryos and larvae

Authors:
Malone MH, Sciaky N, Stalheim L, Hahn KM, Linney E, Johnson GL
Citation:
BMC Biotechnol. 2007 Jul 10;7(1):40 [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: The zebrafish Danio rerio is an important model system for drug discovery and to study cardiovascular...
Organism or Cell Type:
zebrafish
Citation Extract:
Malone MH, Sciaky N, Stalheim L, Hahn KM, Linney E, Johnson GL. Laser-scanning velocimetry: A confocal microscopy method for quantitative measurement of cardiovascular performance in zebrafish embryos and larvae. BMC Biotechnol. 2007 Jul 10;7(1):40 [Epub ahead of print].

Long-term systemic administration of unconjugated morpholino oligomers for therapeutic expression of dystrophin by exon skipping in skeletal muscle: implications for cardiac muscle integrity

Authors:
Malerba A, Boldrin L, Dickson G
Citation:
Nucleic Acid Ther. 2011 Aug;21(4):293-8
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a lethal X-linked inherited disease caused by mutations in the dystrophin gene and...
Delivery Method:
Injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Malerba A, Boldrin L, Dickson G. Long-term systemic administration of unconjugated morpholino oligomers for therapeutic expression of dystrophin by exon skipping in skeletal muscle: implications for cardiac muscle integrity. Nucleic Acid Ther. 2011 Aug;21(4):293-8.

Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations

Authors:
MacInnes AW, Amsterdam A, Whittaker CA, Hopkins N, Lees JA
Citation:
Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10408-13. Epub 2008 Jul 18
Epub:
Not Epub
Abstract:
Zebrafish carrying heterozygous mutations for 17 different ribosomal protein (rp) genes are prone to developing malignant...
Organism or Cell Type:
zebrafish
Citation Extract:
MacInnes AW, Amsterdam A, Whittaker CA, Hopkins N, Lees JA. Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10408-13. Epub 2008 Jul 18.

Lowe syndrome: Between primary cilia assembly and Rac1-mediated membrane remodeling

Authors:
Madhivanan K, Mukherjee D, Aguilar RC
Citation:
Commun Integr Biol. 2012 Nov 1;5(6):641-4. doi: 10.4161/cib.21952
Epub:
Not Epub
Abstract:
Lowe syndrome (LS) is a lethal X-linked genetic disease caused by functional deficiencies of the phosphatidlyinositol 5-...
Organism or Cell Type:
zebrafish
Citation Extract:
Madhivanan K, Mukherjee D, Aguilar RC. Lowe syndrome: Between primary cilia assembly and Rac1-mediated membrane remodeling. Commun Integr Biol. 2012 Nov 1;5(6):641-4. doi: 10.4161/cib.21952.

Maternally-Recruited DCP1A and DCP2 Contribute to Messenger RNA Degradation During Oocyte Maturation and Genome Activation in Mouse

Authors:
Ma J, Flemr M, Strnad H, Svoboda P, Schultz RM
Citation:
Biol Reprod. 2012 Nov 7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The oocyte-to-zygote transition entails transforming a highly differentiated oocyte into totipotent blastomeres and represents...
Organism or Cell Type:
mouse oocytes
Citation Extract:
Ma J, Flemr M, Strnad H, Svoboda P, Schultz RM. Maternally-Recruited DCP1A and DCP2 Contribute to Messenger RNA Degradation During Oocyte Maturation and Genome Activation in Mouse. Biol Reprod. 2012 Nov 7. [Epub ahead of print].

Megalencephalic leukoencephalopathy with subcortical cysts type 1 (MLC1) due to a homozygous deep intronic splicing mutation (c.895-226T>G) abrogated in vitro using an antisense morpholino oligonucleotide

Authors:
Mancini C, Vaula G, Scalzitti L, Cavalieri S, Bertini E, Aiello C, Lucchini C, Gatti RA, Brussino A, Brusco A
Citation:
Neurogenetics. 2012 May 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Megalencephalic leukoencephalopathy with subcortical cysts is an autosomal recessive disease characterized by early onset...
Organism or Cell Type:
cell culture
Citation Extract:
Mancini C, Vaula G, Scalzitti L, Cavalieri S, Bertini E, Aiello C, Lucchini C, Gatti RA, Brussino A, Brusco A. Megalencephalic leukoencephalopathy with subcortical cysts type 1 (MLC1) due to a homozygous deep intronic splicing mutation (c.895-226T>G) abrogated in vitro using an antisense morpholino oligonucleotide. Neurogenetics. 2012 May 3. [Epub ahead of print].

Methionine aminopeptidase 2 is required for hematopoietic stem cell initiation and proliferation

Authors:
Ma AC, Fung TK, Lin RHC, Chung MIS, Yang D, Ekker SC, Leung AYH
Citation:
Blood. 2011 Epub ahead of print] doi:10.1182/blood-2011-04-350173
Epub:
Not Epub
Abstract:
In a chemical screening, we tested the anti-angiogenic effects of fumagillin derivatives and identified fumagillin as an...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma AC, Fung TK, Lin RHC, Chung MIS, Yang D, Ekker SC, Leung AYH. Methionine aminopeptidase 2 is required for hematopoietic stem cell initiation and proliferation. Blood. 2011 Epub ahead of print] doi:10.1182/blood-2011-04-350173.

Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina

Authors:
Luo J, Uribe RA, Hayton S, Calinescu A-A, Gross JM, Hitchcock PF
Citation:
Neural Dev. 2012;7(33). doi:10.1186/1749-8104-7-33
Epub:
Not Epub
Abstract:
Background Midkine is a small heparin binding growth factor expressed in numerous tissues during development. The unique...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Luo J, Uribe RA, Hayton S, Calinescu A-A, Gross JM, Hitchcock PF. Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina. Neural Dev. 2012;7(33). doi:10.1186/1749-8104-7-33.

Mitogen-activated Protein Kinase p38 Regulates the Wnt/Cyclic GMP/Ca2+ Non-canonical Pathway

Authors:
Ma L, Wang HY
Citation:
J Biol Chem. 2007 Sep 28;282(39):28980-90. Epub 2007 Aug 7
Epub:
Not Epub
Abstract:
The non-canonical Wnt/cyclic GMP/Ca(2+)/NF-AT pathway operates via Frizzled-2, a member of the superfamily of G protein-coupled...
Organism or Cell Type:
cell culture: mouse F9 cells
Citation Extract:
Ma L, Wang HY. Mitogen-activated Protein Kinase p38 Regulates the Wnt/Cyclic GMP/Ca2+ Non-canonical Pathway. J Biol Chem. 2007 Sep 28;282(39):28980-90. Epub 2007 Aug 7.

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