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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12454 scientific papers returned from the database with the search filters currently being used below.
There are 12454 scientific papers returned from the database with the search filters currently being used below.
The translational blocking of α5 and α6 integrin subunits affects migration and invasion, and increases sensitivity to carboplatin of SKOV-3 ovarian cancer cell line
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Citation:
Exp Cell Res. 2017 Jan 25. pii: S0014-4827(17)30019-8. doi: 10.1016/j.yexcr.2017.01.010. [Epub ahead of print] Epub:
Not Epub Abstract:
Epithelial ovarian cancer is the most lethal gynecologic malignancy. Integrins, overexpressed in cancer, are involved in... Organism or Cell Type:
cell culture: SKOV-3 ovarian cancer Citation Extract: Villegas-Pineda JC, Toledo-Leyva A, Osorio-Trujillo JC, Hernández-Ramírez VI, Talamás-Rohana P. The translational blocking of α5 and α6 integrin subunits affects migration and invasion, and increases sensitivity to carboplatin of SKOV-3 ovarian cancer cell line. Exp Cell Res. 2017 Jan 25. pii: S0014-4827(17)30019-8. doi: 10.1016/j.yexcr.2017.01.010. [Epub ahead of print]. |
Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development
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Citation:
Dev Biol. 2017 Jan 15;421(2):171-182. doi: 10.1016/j.ydbio.2016.11.021 Epub:
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Mutations in SIX1 and in its co-factor, EYA1, underlie Branchiootorenal Spectrum disorder (BOS), which is characterized by... Organism or Cell Type:
Xenopus Citation Extract: Neilson KM, Abbruzzesse G, Kenyon K, Bartolo V, Krohn P, Alfandari D, Moody SA. Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development. Dev Biol. 2017 Jan 15;421(2):171-182. doi: 10.1016/j.ydbio.2016.11.021. |
An Epha4/Sipa1l3/Wnt pathway regulates eye development and lens maturation
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Citation:
Development. 2017 Jan 15;144(2):321-333. doi: 10.1242/dev.147462 Epub:
Not Epub Abstract:
The signal-induced proliferation-associated family of proteins comprises four members, SIPA1 and SIPA1L1-3. Mutations of the... Delivery Method:
http://dev.biologists.org/content/144/2/321 Organism or Cell Type:
Xenopus Citation Extract: Rothe M, Kanwal N, Dietmann P, Seigfried FA, Hempel A, Schütz D, Reim D, Engels R, Linnemann A, Schmeisser MJ, Bockmann J, Kühl M, Boeckers TM, Kühl SJ. An Epha4/Sipa1l3/Wnt pathway regulates eye development and lens maturation. Development. 2017 Jan 15;144(2):321-333. doi: 10.1242/dev.147462. |
In vivo translatome profiling reveals early defects in ribosome biology underlying SMA pathogenesis
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Citation:
bioRxiv. 2017. doi:10.1101/103481 Epub:
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Background: Genetic alterations impacting on ubiquitously expressed proteins involved in mRNA metabolism often result in... Delivery Method:
i.v. injection Organism or Cell Type:
SMA mice Citation Extract: Bernabò P, Tebaldi T, Groen EJN, Lane FM, Perenthaler E, Mattedi F, Newbery HJ, Zhou H, Zuccotti P, Potrich V, Muntoni F, Quattrone A, Gillingwater TH, Viero1 G. In vivo translatome profiling reveals early defects in ribosome biology underlying SMA pathogenesis. bioRxiv. 2017. doi:10.1101/103481. |
Kif4 Is Essential for Mouse Oocyte Meiosis
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Citation:
PLoS One. 2017 Jan 26;12(1):e0170650. doi: 10.1371/journal.pone.0170650 Epub:
Not Epub Abstract:
Progression through the meiotic cell cycle must be strictly regulated in oocytes to generate viable embryos and offspring.... Delivery Method:
microinjection Organism or Cell Type:
mouse oocyte Citation Extract: Camlin NJ, McLaughlin EA, Holt JE. Kif4 Is Essential for Mouse Oocyte Meiosis. PLoS One. 2017 Jan 26;12(1):e0170650. doi: 10.1371/journal.pone.0170650. |
The invariant cleavage pattern displayed by ascidian embryos depends on spindle positioning along the cell's longest axis in the apical plane and relies on asynchronous cell divisions
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Citation:
Elife. 2017 Jan 25;6. pii: e19290. doi: 10.7554/eLife.19290. [Epub ahead of print] Epub:
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The ascidian embryo is an ideal system to investigate how cell position is determined during embryogenesis. Using 3D timelapse... Delivery Method:
microinjection Organism or Cell Type:
Phallusia mammillata (ascidian) Citation Extract: Dumollard R, Minc N, Salez G, Ben Aicha S, Bekkouche F, Hebras C, Besnardeau L, McDougall A. The invariant cleavage pattern displayed by ascidian embryos depends on spindle positioning along the cell's longest axis in the apical plane and relies on asynchronous cell divisions. Elife. 2017 Jan 25;6. pii: e19290. doi: 10.7554/eLife.19290. [Epub ahead of print]. |
Cilia Control Vascular Mural Cell Recruitment in Vertebrates
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Citation:
Cell Rep. 2017 Jan 24;18(4):1033-1047. doi: 10.1016/j.celrep.2016.12.044 Epub:
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Vascular mural cells (vMCs) are essential components of the vertebrate vascular system, controlling blood vessel maturation and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen X, Gays D, Milia C, Santoro MM. Cilia Control Vascular Mural Cell Recruitment in Vertebrates. Cell Rep. 2017 Jan 24;18(4):1033-1047. doi: 10.1016/j.celrep.2016.12.044. |
Acetylation promotes TyrRS nuclear translocation to prevent oxidative damage
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Citation:
Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):687-692. doi: 10.1073/pnas.1608488114 Epub:
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Tyrosyl-tRNA synthetase (TyrRS) is well known for its essential aminoacylation function in protein synthesis. Recently, TyrRS... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cao X, Li C, Xiao S, Tang Y, Huang J, Zhao S, Li X, Li J, Zhang R, Yu W. Acetylation promotes TyrRS nuclear translocation to prevent oxidative damage. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):687-692. doi: 10.1073/pnas.1608488114. |
Early frameshift alleles of zebrafish tbx5a that fail to develop the heartstrings phenotype
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Citation:
bioRxiv. 2017. doi:10.1101/103168 Epub:
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Tbx5 is a key transcription factor for vertebrate heart and forelimb development that causes Holt-Oram syndrome when mutated in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chiavacci E, Kirchgeorg L, Felker A, Burger A, Mosimann C. Early frameshift alleles of zebrafish tbx5a that fail to develop the heartstrings phenotype. bioRxiv. 2017. doi:10.1101/103168. |
Genetic Drivers of Kidney Defects in the DiGeorge Syndrome
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Citation:
N Engl J Med. 2017 Jan 25. doi: 10.1056/NEJMoa1609009. [Epub ahead of print] Epub:
Yes Abstract:
Background The DiGeorge syndrome, the most common of the microdeletion syndromes, affects multiple organs, including the heart... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lopez-Rivera E, Liu YP, Verbitsky M, Anderson BR, Capone VP, Otto EA, Yan Z, Mitrotti A, Martino J, Steers NJ, Fasel DA, Vukojevic K, Deng R, Racedo SE, Liu Q, Werth M, Westland R, Vivante A, Makar GS, Bodria M, Sampson MG, Gillies CE, Vega-Warner V, Maiorana M, Petrey DS, Honig B, Lozanovski VJ, Salomon R, Heidet L, Carpentier W, Gaillard D, Carrea A, Gesualdo L, Cusi D, Izzi C, Scolari F, van Wijk JA, Arapovic A, Saraga-Babic M, Saraga M, Kunac N, Samii A, McDonald-McGinn DM, Crowley TB, Zackai EH, Drozdz D, Miklaszewska M, Tkaczyk M, Sikora P, Szczepanska M, Mizerska-Wasiak M, <authors deleted - database limit> Tasic V, Latos-Bielenska A, Materna-Kiryluk A, Allegri L, Wong CS, Drummond IA, D'Agati V, Imamoto A, Barasch JM, Hildebrandt F, Kiryluk K, Lifton RP, Morrow BE, Jeanpierre C, Papaioannou VE, Ghiggeri GM, Gharavi AG, Katsanis N, Sanna-Cherchi S. Genetic Drivers of Kidney Defects in the DiGeorge Syndrome. N Engl J Med. 2017 Jan 25. doi: 10.1056/NEJMoa1609009. [Epub ahead of print]. |