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Morpholinos blocking mRNA localization elements

Citations of papers with Morpholinos blocking mRNA localization elements are here.


Morpholino oligos have been shown effective for blocking localization elements on mRNAs, inhibiting binding of the RNA recognition proteins needed for directed movement of the mRNAs.

References


Gilligan PC, Kumari P, Lim S, Cheong A, Chang A, Sampath K.
Conservation defines functional motifs in the squint/nodal-related 1 RNA dorsal localization element. Nucleic Acids Res. 2011 Apr 1;39(8):3340-9. Epub 2010 Dec 10.

Rabinowitz JS, Lambert JD. Spiralian quartet developmental potential is regulated by specific localization elements that mediate asymmetric RNA segregation. Development. 2010 Nov 1. [Epub ahead of print]

Koebernick K, Loeber J, Arthur PK, Tarbashevich K, Pieler T. Elr-type proteins protect Xenopus Dead end mRNA from miR-18-mediated clearance in the soma. Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16148-53. Epub 2010 Aug 30

Arthur PK, Claussen M, Koch S, Tarbashevich K, Jahn O, Pieler T. Participation of Xenopus Elr-type proteins in vegetal mRNA localization during oogenesis. J Biol Chem. 2009 Jul 24;284(30):19982-92. Epub 2009 May 20.