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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 8581 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans

Authors:
Lansdon LA, Darbro BW, Petrin AL, Hulstrand AM, Standley JM, Brouillette RB, Long A, Mansilla MA, Cornell RA, Murray JC, Houston DW, Manak R
Citation:
Genetics. 2017;[Epub ahead of print] doi:10.1534/genetics.117.300535
Abstract:
Orofacial clefts are one of the most common birth defects, affecting 1-2 per 1000 births, and have a complex etiology. High-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Lansdon LA, Darbro BW, Petrin AL, Hulstrand AM, Standley JM, Brouillette RB, Long A, Mansilla MA, Cornell RA, Murray JC, Houston DW, Manak R. Identification of Isthmin 1 as a Novel Clefting and Craniofacial Patterning Gene in Humans. Genetics. 2017;[Epub ahead of print] doi:10.1534/genetics.117.300535.

Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome

Authors:
Thorsen K, Dam VS, Kjaer-Sorensen K, Pedersen LN, Skeberdis VA, Jurevičius J, Treinys R, Petersen IMBS, Nielsen MS, Oxvig C, Morth JP, Matchkov VV, Aalkjær C, Bundgaard H, Jensen HK
Citation:
Nat Comm. 2017;8:1696. doi:10.1038/s41467-017-01630-0
Abstract:
Patients with short QT syndrome (SQTS) may present with syncope, ventricular fibrillation or sudden cardiac death. Six SQTS...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thorsen K, Dam VS, Kjaer-Sorensen K, Pedersen LN, Skeberdis VA, Jurevičius J, Treinys R, Petersen IMBS, Nielsen MS, Oxvig C, Morth JP, Matchkov VV, Aalkjær C, Bundgaard H, Jensen HK. Loss-of-activity-mutation in the cardiac chloride-bicarbonate exchanger AE3 causes short QT syndrome. Nat Comm. 2017;8:1696. doi:10.1038/s41467-017-01630-0.

Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo [version 1; referees: awaiting peer review]

Authors:
Eve AMJ, Smith JC
Citation:
Wellcome Open Res. 2017;2:111. doi:10.12688/wellcomeopenres.12394.1
Abstract:
Background: Previous work in the zebrafish embryo has shown that laminin γ-3 (lamc3) is enriched in endothelial cells marked by...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Eve AMJ, Smith JC. Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo [version 1; referees: awaiting peer review]. Wellcome Open Res. 2017;2:111. doi:10.12688/wellcomeopenres.12394.1.

Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning

Authors:
Pelliccia JL, Jindal GA, Burdine RD
Citation:
eLife. 2017;6:e28635 doi:10.7554/eLife.28635
Abstract:
Vertebrate embryonic patterning depends on signaling from Nodal, a TGFβ superfamily member. There are three Nodal orthologs in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pelliccia JL, Jindal GA, Burdine RD. Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning. eLife. 2017;6:e28635 doi:10.7554/eLife.28635.

The zinc finger gene Nolz1 regulates the formation of retinal progenitor cells and suppresses the Lim3/Lhx3 phenotype of retinal bipolar cells in chicken retina

Authors:
Blixt MKE, Konjusha D, Ring H, Hallböök F
Citation:
Dev Dyn. 2017 Nov 15. doi: 10.1002/dvdy.24607. [Epub ahead of print]
Abstract:
BACKGROUND: The zinc-finger transcription factor Nolz1 regulates spinal cord neuron development by interacting with the...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Blixt MKE, Konjusha D, Ring H, Hallböök F. The zinc finger gene Nolz1 regulates the formation of retinal progenitor cells and suppresses the Lim3/Lhx3 phenotype of retinal bipolar cells in chicken retina. Dev Dyn. 2017 Nov 15. doi: 10.1002/dvdy.24607. [Epub ahead of print].

Transient cardiomyocyte fusion regulates cardiac development in zebrafish

Authors:
Sawamiphak S, Kontarakis Z, Filosa A, Reischauer S, Stainier DYR
Citation:
Nat Comm. 2017;8:1525. doi:10.1038/s41467-017-01555-8
Abstract:
Cells can sacrifice their individuality by fusing, but the prevalence and significance of this process are poorly understood....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sawamiphak S, Kontarakis Z, Filosa A, Reischauer S, Stainier DYR. Transient cardiomyocyte fusion regulates cardiac development in zebrafish. Nat Comm. 2017;8:1525. doi:10.1038/s41467-017-01555-8.

A Nonredundant Role for the TRPM6 Channel in Neural Tube Closure

Authors:
Komiya Y, Bai Z, Cai N, Lou L, Al-Saadi N, Mezzacappa C, Habas R, Runnels LW
Citation:
Sci Rep. 2017;7:15623. doi:10.1038/s41598-017-15855-y
Abstract:
In humans, germline mutations in Trpm6 cause autosomal dominant hypomagnesemia with secondary hypocalcemia disorder. Loss of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Komiya Y, Bai Z, Cai N, Lou L, Al-Saadi N, Mezzacappa C, Habas R, Runnels LW. A Nonredundant Role for the TRPM6 Channel in Neural Tube Closure. Sci Rep. 2017;7:15623. doi:10.1038/s41598-017-15855-y.

Intraflagellar transport proteins are involved in thrombocyte filopodia formation and secretion

Authors:
Radhakrishnan U, Alsrhani A, Sundaramoorthi H, Khandekar G, Kashyap M, Fuchs JL, Perkins BD, Omori Y, Jagadeeswaran P
Citation:
Platelets. 2017 Nov 10:1-10. doi: 10.1080/09537104.2017.1361524. [Epub ahead of print]
Abstract:
Intraflagellar transport (IFT) proteins are vital for the genesis and maintenance of cilia. Our identification of ift122...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Radhakrishnan U, Alsrhani A, Sundaramoorthi H, Khandekar G, Kashyap M, Fuchs JL, Perkins BD, Omori Y, Jagadeeswaran P. Intraflagellar transport proteins are involved in thrombocyte filopodia formation and secretion. Platelets. 2017 Nov 10:1-10. doi: 10.1080/09537104.2017.1361524. [Epub ahead of print].

Temporally distinct transcriptional regulation of myocyte dedifferentiation and Myofiber growth during muscle regeneration

Authors:
Louie KW, Saera-Vila A, Kish PE, Colacino JA, Kahana A
Citation:
BMC Genomics. 2017 Nov 9;18(1):854. doi: 10.1186/s12864-017-4236-y
Abstract:
BACKGROUND: Tissue regeneration requires a series of steps, beginning with generation of the necessary cell mass, followed by...
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Louie KW, Saera-Vila A, Kish PE, Colacino JA, Kahana A. Temporally distinct transcriptional regulation of myocyte dedifferentiation and Myofiber growth during muscle regeneration. BMC Genomics. 2017 Nov 9;18(1):854. doi: 10.1186/s12864-017-4236-y.

Identification of Staphylococcus aureus Factors Required for Pathogenicity and Growth in Human Blood

Authors:
Connolly J, Boldock E, Prince LR, Renshaw SA, Whyte MK, Foster SJ
Citation:
Infect Immun. 2017 Oct 18;85(11). pii: e00337-17. doi: 10.1128/IAI.00337-17
Abstract:
Staphylococcus aureus is a human commensal but also has devastating potential as an opportunistic pathogen. S. aureus...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Connolly J, Boldock E, Prince LR, Renshaw SA, Whyte MK, Foster SJ. Identification of Staphylococcus aureus Factors Required for Pathogenicity and Growth in Human Blood. Infect Immun. 2017 Oct 18;85(11). pii: e00337-17. doi: 10.1128/IAI.00337-17.

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