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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 8170 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

Authors:
Range RC, Martinez-Bartolomé M, Burr SD
Citation:
J Vis Exp. 2017;120:e55113. doi:10.3791/55113
Abstract:
Remarkably few cell-to-cell signal transduction pathways are necessary during embryonic development to generate the large...
Organism or Cell Type:
sea urchin
Citation Extract:
Range RC, Martinez-Bartolomé M, Burr SD. The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions. J Vis Exp. 2017;120:e55113. doi:10.3791/55113.

Hyaluronic acid synthesis is required for zebrafish tail fin regeneration

Authors:
Ouyang X, Panetta NJ, Talbott MD, Payumo AY, Halluin C, Longaker MT, Chen JK
Citation:
PLoS One. 2017 Feb 16;12(2):e0171898. doi: 10.1371/journal.pone.0171898
Abstract:
Using genome-wide transcriptional profiling and whole-mount expression analyses of zebrafish larvae, we have identified...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ouyang X, Panetta NJ, Talbott MD, Payumo AY, Halluin C, Longaker MT, Chen JK. Hyaluronic acid synthesis is required for zebrafish tail fin regeneration. PLoS One. 2017 Feb 16;12(2):e0171898. doi: 10.1371/journal.pone.0171898.

The enteric nervous system promotes intestinal health by constraining microbiota composition

Authors:
Rolig AS, Mittge EK, Ganz J, Troll JV, Melancon E, Wiles TJ, Alligood K, Stephens WZ, Eisen JS, Guillemin K
Citation:
PLoS Biol. 2017 Feb 16;15(2):e2000689. doi: 10.1371/journal.pbio.2000689
Abstract:
Sustaining a balanced intestinal microbial community is critical for maintaining intestinal health and preventing chronic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rolig AS, Mittge EK, Ganz J, Troll JV, Melancon E, Wiles TJ, Alligood K, Stephens WZ, Eisen JS, Guillemin K. The enteric nervous system promotes intestinal health by constraining microbiota composition. PLoS Biol. 2017 Feb 16;15(2):e2000689. doi: 10.1371/journal.pbio.2000689.

Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency

Authors:
Gavino C, Landekic M, Zeng J, Wu N, Jung S, Zhong M-C, Cohen-Blanchet AC, Langelier M, Neyret O, Lejtenyi D, Rochefort C, Cotton-Montpetit J, McCusker C, Mazer B, Veillette A, Vinh DC
Citation:
J Allergy Clin Immunol. 2017;[Epub ahead of print] doi:10.1016/j.jaci.2017.02.002
Abstract:
An adult with hypomorphic ZAP-70 deficiency due to de novo donor splice site mutation manifested autoimmunity, infections...
Citation Extract:
Gavino C, Landekic M, Zeng J, Wu N, Jung S, Zhong M-C, Cohen-Blanchet AC, Langelier M, Neyret O, Lejtenyi D, Rochefort C, Cotton-Montpetit J, McCusker C, Mazer B, Veillette A, Vinh DC. Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency. J Allergy Clin Immunol. 2017;[Epub ahead of print] doi:10.1016/j.jaci.2017.02.002.

Glycerophosphodiesterase GDE2 affects pancreas differentiation in zebrafish

Authors:
Veen M, van Pelt J, Mans LA, Moolenaar WH, Haramis A-PG
Citation:
bioRxiv. 2017. doi:10.1101/108779
Abstract:
Notch signaling plays an essential role in the proliferation, differentiation and cell fate determination of various tissues,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veen M, van Pelt J, Mans LA, Moolenaar WH, Haramis A-PG. Glycerophosphodiesterase GDE2 affects pancreas differentiation in zebrafish. bioRxiv. 2017. doi:10.1101/108779.

Mechanical stretch triggers rapid epithelial cell division through Piezo1

Authors:
Gudipaty SA, Lindblom J, Loftus PD, Redd MJ, Edes K, Davey CF, Krishnegowda V, Rosenblatt J
Citation:
Nature. 2017;[Epub ahead of print] doi:10.1038/nature21407
Abstract:
Despite acting as a barrier for the organs they encase, epithelial cells turn over at some of the fastest rates in the body....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gudipaty SA, Lindblom J, Loftus PD, Redd MJ, Edes K, Davey CF, Krishnegowda V, Rosenblatt J. Mechanical stretch triggers rapid epithelial cell division through Piezo1. Nature. 2017;[Epub ahead of print] doi:10.1038/nature21407.

The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection

Authors:
Hazra B, Kumawat KL, Basu A
Citation:
Sci Signal. 2017;10(466):eaaf5185. doi:10.1126/scisignal.aaf5185
Abstract:
Effective recognition of viral components and the subsequent stimulation of the production of type I interferons (IFNs) is...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
BALB/c mice
Citation Extract:
Hazra B, Kumawat KL, Basu A. The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection. Sci Signal. 2017;10(466):eaaf5185. doi:10.1126/scisignal.aaf5185.

Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction

Authors:
Elmonem MA, Khalil R, Khodaparast L, Khodaparast L, Arcolino FO, Morgan J, Pastore A, Tylzanowski P, Ny A, Lowe M, de Witte PA, Baelde HJ, van den Heuvel LP, Levtchenko E
Citation:
Sci Rep. 2017;7:42583. doi:10.1038/srep42583
Abstract:
The human ubiquitous protein cystinosin is responsible for transporting the disulphide amino acid cystine from the lysosomal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Elmonem MA, Khalil R, Khodaparast L, Khodaparast L, Arcolino FO, Morgan J, Pastore A, Tylzanowski P, Ny A, Lowe M, de Witte PA, Baelde HJ, van den Heuvel LP, Levtchenko E. Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction. Sci Rep. 2017;7:42583. doi:10.1038/srep42583.

Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling

Authors:
Han W, Lee H, Han J-K
Citation:
Sci Rep. 2017;7:42590 doi:10.1038/srep42590
Abstract:
The Tcf/Lef family of transcription factors mediates the Wnt/β-catenin pathway that is involved in a wide range of biological...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Han W, Lee H, Han J-K. Ubiquitin C-terminal hydrolase37 regulates Tcf7 DNA binding for the activation of Wnt signalling. Sci Rep. 2017;7:42590 doi:10.1038/srep42590.

Dual roles of Akirin2 during Xenopus neural development

Authors:
Liu X, Xia Y, Tang J, Ma L, Li C, Ma P, Mao B
Citation:
J Biol Chem. 2017 Feb 13. pii: jbc.M117.777110. doi: 10.1074/jbc.M117.777110. [Epub ahead of print]
Abstract:
To ensure correct spatial and temporal patterning, embryos must maintain pluripotent cell populations and control when cells...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu X, Xia Y, Tang J, Ma L, Li C, Ma P, Mao B. Dual roles of Akirin2 during Xenopus neural development. J Biol Chem. 2017 Feb 13. pii: jbc.M117.777110. doi: 10.1074/jbc.M117.777110. [Epub ahead of print].

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