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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 8308 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Functional Manipulation of Maternal Gene Products Using In Vitro Oocyte Maturation in Zebrafish

Authors:
Welch EL, Eno CC, Nair S, Lindeman RE, Pelegri F
Citation:
JoVE. 2017;122:e55213. doi:10.3791/55213
Abstract:
Cellular events that take place during the earliest stages of animal embryonic development are driven by maternally derived...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Welch EL, Eno CC, Nair S, Lindeman RE, Pelegri F. Functional Manipulation of Maternal Gene Products Using In Vitro Oocyte Maturation in Zebrafish. JoVE. 2017;122:e55213. doi:10.3791/55213.

Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity

Authors:
Xu B, Zhang Y, Du XF, Li J, Zi HX, Bu JW, Yan Y, Han H, Du JL
Citation:
Cell Res. 2017 Apr 21. doi: 10.1038/cr.2017.62. [Epub ahead of print]
Abstract:
Vascular integrity helps maintain brain microenvironment homeostasis, which is critical for the normal development and function...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xu B, Zhang Y, Du XF, Li J, Zi HX, Bu JW, Yan Y, Han H, Du JL. Neurons secrete miR-132-containing exosomes to regulate brain vascular integrity. Cell Res. 2017 Apr 21. doi: 10.1038/cr.2017.62. [Epub ahead of print].

CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions

Authors:
Chrifi I, Louzao-Martinez L, Brandt M, van Dijk CGM, Burgisser P, Zhu C, Kros JM, Duncker DJ, Cheng C
Citation:
Arter Thromb Vasc Biol. 2017;[Epub ahead of print] doi:10.1161/ATVBAHA.116.308792
Abstract:
Objective: Decrease in VE-cadherin adherens junctions reduces vascular stability, whereas disruption of adherens junctions is a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chrifi I, Louzao-Martinez L, Brandt M, van Dijk CGM, Burgisser P, Zhu C, Kros JM, Duncker DJ, Cheng C. CMTM3 (CKLF-Like Marvel Transmembrane Domain 3) Mediates Angiogenesis by Regulating Cell Surface Availability of VE-Cadherin in Endothelial Adherens Junctions. Arter Thromb Vasc Biol. 2017;[Epub ahead of print] doi:10.1161/ATVBAHA.116.308792.

Ultrasensitive Detection of MicroRNAs with Morpholino-Functionalized Nanochannel Biosensor

Authors:
Liao T, Li X, Tong Q, Zou K, Zhang H, Tang L, Sun Z, Zhang G-J
Citation:
Anal Chem. 2017;[Just accepted] doi:10.1021/acs.analchem.7b00487
Abstract:
Here we demonstrate a phosphorodiamidate morpholino oligos (PMO)-functionlized nanochannel biosensor for label-free detection...
Citation Extract:
Liao T, Li X, Tong Q, Zou K, Zhang H, Tang L, Sun Z, Zhang G-J. Ultrasensitive Detection of MicroRNAs with Morpholino-Functionalized Nanochannel Biosensor. Anal Chem. 2017;[Just accepted] doi:10.1021/acs.analchem.7b00487.

Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation

Authors:
Rudigier LJ, Dame C, Scholz H, Kirschner KM
Citation:
PLoS ONE. 2017;12(4):e0176296. doi:10.1371/journal.pone.0176296
Abstract:
Gonad morphogenesis relies on the correct spatiotemporal expression of a number of genes that together fulfill the...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse gonad explants
Citation Extract:
Rudigier LJ, Dame C, Scholz H, Kirschner KM. Ex vivo cultures combined with vivo-morpholino induced gene knockdown provide a system to assess the role of WT1 and GATA4 during gonad differentiation. PLoS ONE. 2017;12(4):e0176296. doi:10.1371/journal.pone.0176296.

Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy

Authors:
Boyd PJ, Tu W-Y, Shorrock HK, Groen EJN, Carter RN, Powis RA, Thomson SR, Thomson D, Graham LC, Motyl AAL, Wishart TM, Highley JR, Morton NM, Becker T, Becker CG, Heath PR, Gillingwater TH
Citation:
PLoS Genet. 2017;[uncorrected proof] doi:10.1371/journal.pgen.1006744
Abstract:
Degeneration and loss of lower motor neurons is the major pathological hallmark of spinal muscular atrophy (SMA), resulting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boyd PJ, Tu W-Y, Shorrock HK, Groen EJN, Carter RN, Powis RA, Thomson SR, Thomson D, Graham LC, Motyl AAL, Wishart TM, Highley JR, Morton NM, Becker T, Becker CG, Heath PR, Gillingwater TH. Bioenergetic status modulates motor neuron vulnerability and pathogenesis in a zebrafish model of spinal muscular atrophy. PLoS Genet. 2017;[uncorrected proof] doi:10.1371/journal.pgen.1006744.

Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain

Authors:
Albuixech-Crespo B, López-Blanch L, Burguera D, Maeso I, Sánchez-Arrones L, Moreno-Bravo JA, Somorjai I, Pascual-Anaya J, Puelles E, Bovolenta P, Garcia-Fernàndez J, Puelles L, Irimia M, Ferran JL
Citation:
PLoS Biol. 2017;15(4):e2001573. doi:10.1371/journal.pbio.2001573
Abstract:
All vertebrate brains develop following a common Bauplan defined by anteroposterior (AP) and dorsoventral (DV) subdivisions,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Albuixech-Crespo B, López-Blanch L, Burguera D, Maeso I, Sánchez-Arrones L, Moreno-Bravo JA, Somorjai I, Pascual-Anaya J, Puelles E, Bovolenta P, Garcia-Fernàndez J, Puelles L, Irimia M, Ferran JL. Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain. PLoS Biol. 2017;15(4):e2001573. doi:10.1371/journal.pbio.2001573.

An Integrative Developmental Genomics and Systems Biology Approach To Identify An In Vivo Sox Trio-Mediated Gene Regulatory Network In Murine Embryos

Authors:
Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PP, Prabhakar S, Lufkin T
Citation:
BioMed Res Internat. 2017;[Epub ahead of print]
Abstract:
Embryogenesis is an intricate process involving multiple genes and pathways. Some of the key transcription factors controlling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PP, Prabhakar S, Lufkin T. An Integrative Developmental Genomics and Systems Biology Approach To Identify An In Vivo Sox Trio-Mediated Gene Regulatory Network In Murine Embryos. BioMed Res Internat. 2017;[Epub ahead of print] .

A new locus regulating MICALL2 expression was identified for association with executive inhibition in children with attention deficit hyperactivity disorder

Authors:
Yang L, Chang S, Lu Q, Zhang Y, Wu Z, Sun X, Cao Q, Qian Y, Jia T, Xu B, Duan Q, Li Y, Zhang K, Schumann G, Liu D, Wang J, Wang Y, Lu L
Citation:
Molec Psychiatry. 2017;[Epub ahead of print] doi:10.1038/mp.2017.74
Abstract:
Impaired executive inhibition is a core deficit of attention deficit hyperactivity disorder (ADHD), which is a common childhood...
Organism or Cell Type:
zebrafish
Citation Extract:
Yang L, Chang S, Lu Q, Zhang Y, Wu Z, Sun X, Cao Q, Qian Y, Jia T, Xu B, Duan Q, Li Y, Zhang K, Schumann G, Liu D, Wang J, Wang Y, Lu L. A new locus regulating MICALL2 expression was identified for association with executive inhibition in children with attention deficit hyperactivity disorder. Molec Psychiatry. 2017;[Epub ahead of print] doi:10.1038/mp.2017.74.

Competition between histone and transcription factor binding regulates the onset of transcription in zebrafish embryos

Authors:
Joseph SR, Pálfy M, Hilbert L, Kumar M, Karschau J, Zaburdaev V, Shevchenko A, Vastenhouw NL
Citation:
bioRxiv. 2017;doi:10.1101/125716
Abstract:
Upon fertilization, the genome of animal embryos remains transcriptionally inactive until the maternal-to-zygotic transition....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Joseph SR, Pálfy M, Hilbert L, Kumar M, Karschau J, Zaburdaev V, Shevchenko A, Vastenhouw NL. Competition between histone and transcription factor binding regulates the onset of transcription in zebrafish embryos. bioRxiv. 2017;doi:10.1101/125716.

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