You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 8953 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Glycerophosphodiesterase GDE2/GDPD5 affects pancreas differentiation in zebrafish

Authors:
van Veen M, Mans LA, Matas-Rico E, van Pelt J, Perrakis A, Moolenaar WH, Haramis AG
Citation:
Int J Biochem Cell Biol. 2018 Jan;94:71-78. doi: 10.1016/j.biocel.2017.11.015. Epub 2017 Dec 22
Abstract:
Notch signaling plays an essential role in the proliferation, differentiation and cell fate determination of various tissues,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van Veen M, Mans LA, Matas-Rico E, van Pelt J, Perrakis A, Moolenaar WH, Haramis AG. Glycerophosphodiesterase GDE2/GDPD5 affects pancreas differentiation in zebrafish. Int J Biochem Cell Biol. 2018 Jan;94:71-78. doi: 10.1016/j.biocel.2017.11.015. Epub 2017 Dec 22.

Increased number and activity of a lateral subpopulation of hypothalamic orexin/hypocretin neurons underlies the expression of an addicted state in rats

Authors:
James MH, Stopper CM, Zimmer BA, Koll NE, Bowrey HE, Aston-Jones G
Citation:
Biol Phych. 2018;[Epub ahead of print] doi:10.1016/j.biopsych.2018.07.022
Abstract:
Background: The orexin system is important for reward-driven motivation but has not been implicated in the expression of a...
Delivery Method:
injection
Organism or Cell Type:
Rattus (rat)
Citation Extract:
James MH, Stopper CM, Zimmer BA, Koll NE, Bowrey HE, Aston-Jones G. Increased number and activity of a lateral subpopulation of hypothalamic orexin/hypocretin neurons underlies the expression of an addicted state in rats. Biol Phych. 2018;[Epub ahead of print] doi:10.1016/j.biopsych.2018.07.022.

YAP/TAZ-TEAD Activity Links Mechanical Cues To Specific Cell Fate Within The Hindbrain Boundaries

Authors:
Voltes A, Hevia CF, Dingare C, Calzolari S, Terriente J, Norden C, Lecaudey V, Pujades C
Citation:
bioRXive. 2018;[Epub] doi:10.1101/366351
Abstract:
How embryonic cells perceive their microenvironment through physical/mechanical cues during morphogenesis remains largely...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Voltes A, Hevia CF, Dingare C, Calzolari S, Terriente J, Norden C, Lecaudey V, Pujades C. YAP/TAZ-TEAD Activity Links Mechanical Cues To Specific Cell Fate Within The Hindbrain Boundaries. bioRXive. 2018;[Epub] doi:10.1101/366351.

CMTM4 regulates angiogenesis by promoting cell surface recycling of VE-cadherin to endothelial adherens junctions

Authors:
Chrifi I, Louzao-Martinez L, Brandt MM, van Dijk CGM, Bürgisser PE, Zhu C, Kros JM, Verhaar MC, Duncker DJ, Cheng C
Citation:
Angiogenesis. 2018 Aug 10. doi: 10.1007/s10456-018-9638-1. [Epub ahead of print]
Abstract:
Vascular endothelial (VE) cadherin is a key component of endothelial adherens junctions (AJs) and plays an important role in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chrifi I, Louzao-Martinez L, Brandt MM, van Dijk CGM, Bürgisser PE, Zhu C, Kros JM, Verhaar MC, Duncker DJ, Cheng C. CMTM4 regulates angiogenesis by promoting cell surface recycling of VE-cadherin to endothelial adherens junctions. Angiogenesis. 2018 Aug 10. doi: 10.1007/s10456-018-9638-1. [Epub ahead of print].

Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: Analysis using transgenic and mutant zebrafish

Authors:
Peters MJ, Parker SK, Grim J, Allard CAH, Levin J, Detrich HW 3rd
Citation:
Biol Open. 2018 Aug 10. pii: bio.035576. doi: 10.1242/bio.035576. [Epub ahead of print]
Abstract:
Hemogen is a vertebrate transcription factor that performs important functions in erythropoiesis and testicular development and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peters MJ, Parker SK, Grim J, Allard CAH, Levin J, Detrich HW 3rd. Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: Analysis using transgenic and mutant zebrafish. Biol Open. 2018 Aug 10. pii: bio.035576. doi: 10.1242/bio.035576. [Epub ahead of print].

A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing's family of tumors

Authors:
Annalora AJ, O'Neil S, Bushman JD, Summerton JE, Marcus CB, Iversen PL
Citation:
Oncotarget. 2018 Jul 17;9(55):30568-30586. doi: 10.18632/oncotarget.25736. eCollection 2018 Jul 17
Abstract:
Ewing's sarcoma treatment failures are associated with high mortality indicating a need for new therapeutic approaches. We...
Delivery Method:
fatty acid conjugate & Endo-Porter
Organism or Cell Type:
cell culture: TC-32 & CHLA-10 EFT lines and HEK293 renal epithelial control cells
Citation Extract:
Annalora AJ, O'Neil S, Bushman JD, Summerton JE, Marcus CB, Iversen PL. A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing's family of tumors. Oncotarget. 2018 Jul 17;9(55):30568-30586. doi: 10.18632/oncotarget.25736. eCollection 2018 Jul 17.

Involvement of Kif4a in Spindle Formation and Chromosome Segregation in Mouse Oocytes

Authors:
Tang F, Pan MH, Lu Y, Wan X, Zhang Y, Sun SC
Citation:
Aging Dis. 2018 Aug 1;9(4):623-633. doi: 10.14336/AD.2017.0901. eCollection 2018 Aug
Abstract:
Kif4a, a member of the kinesin superfamily, has been reported to participate in a series of cellular processes such as...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Tang F, Pan MH, Lu Y, Wan X, Zhang Y, Sun SC. Involvement of Kif4a in Spindle Formation and Chromosome Segregation in Mouse Oocytes. Aging Dis. 2018 Aug 1;9(4):623-633. doi: 10.14336/AD.2017.0901. eCollection 2018 Aug.

Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development

Authors:
Astone M, Lai JKH, Dupont S, Stainier DYR, Argenton F, Vettori A
Citation:
Sci Rep. 2018 Jul 5;8(1):10189. doi: 10.1038/s41598-018-27657-x
Abstract:
As effectors of the Hippo signaling cascade, YAP1 and TAZ are transcriptional regulators playing important roles in development...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Astone M, Lai JKH, Dupont S, Stainier DYR, Argenton F, Vettori A. Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development. Sci Rep. 2018 Jul 5;8(1):10189. doi: 10.1038/s41598-018-27657-x.

Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS

Authors:
Tantzer S, Sperle K, Kenaley K, Taube J, Hobson GM
Citation:
Mol Ther Nucleic Acids. 2018;12:420-432. doi:10.1016/j.omtn.2018.05.019
Abstract:
DNA variants of the proteolipid protein 1 gene (PLP1) that shift PLP1/DM20 alternative splicing away from the PLP1 form toward...
Delivery Method:
Endo-Porter, i.c.v. injection
Organism or Cell Type:
cell culture: Oli-neu (immortalized oligodendrocyte precursor), mice
Citation Extract:
Tantzer S, Sperle K, Kenaley K, Taube J, Hobson GM. Morpholino Antisense Oligomers as a Potential Therapeutic Option for the Correction of Alternative Splicing in PMD, SPG2, and HEMS. Mol Ther Nucleic Acids. 2018;12:420-432. doi:10.1016/j.omtn.2018.05.019.

RES complex is associated with intron definition and required for zebrafish early embryogenesis

Authors:
Fernandez JP, Moreno-Mateos MA, Gohr A, Miao L, Chan SH, Irimia M, Giraldez AJ
Citation:
PLoS Genet. 2018 Jul 3;14(7):e1007473. doi: 10.1371/journal.pgen.1007473. eCollection 2018 Jul
Abstract:
Pre-mRNA splicing is a critical step of gene expression in eukaryotes. Transcriptome-wide splicing patterns are complex and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fernandez JP, Moreno-Mateos MA, Gohr A, Miao L, Chan SH, Irimia M, Giraldez AJ. RES complex is associated with intron definition and required for zebrafish early embryogenesis. PLoS Genet. 2018 Jul 3;14(7):e1007473. doi: 10.1371/journal.pgen.1007473. eCollection 2018 Jul.

Pages