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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 8705 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Zebrafish cdc6 hypomorphic mutation causes Meier-Gorlin syndrome-like phenotype

Authors:
Yao L, Chen J, Wu X, Jia S, Meng A
Citation:
Hum Molec Genet. 20-18;26(21):4168-80. doi:10.1093/hmg/ddx305
Abstract:
Cell Division Cycle 6 (Cdc6) is a component of pre-replicative complex (preRC) forming on DNA replication origins in eukaryotes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yao L, Chen J, Wu X, Jia S, Meng A. Zebrafish cdc6 hypomorphic mutation causes Meier-Gorlin syndrome-like phenotype. Hum Molec Genet. 20-18;26(21):4168-80. doi:10.1093/hmg/ddx305.

The Beta-Adrenergic Agonist Salbutamol Modulates Neuromuscular Junction Formation in Zebrafish Models of Human Myasthenic Syndromes

Authors:
McMacken G, Cox D, Roos A, Müller J, Whittaker R, Lochmüller H
Citation:
Hum Molec Genet. 2018;[Epub ahead of print] doi:10.1093/hmg/ddy062
Abstract:
Inherited defects of the neuromuscular junction (NMJ) comprise an increasingly diverse range of disorders, termed congenital...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McMacken G, Cox D, Roos A, Müller J, Whittaker R, Lochmüller H. The Beta-Adrenergic Agonist Salbutamol Modulates Neuromuscular Junction Formation in Zebrafish Models of Human Myasthenic Syndromes. Hum Molec Genet. 2018;[Epub ahead of print] doi:10.1093/hmg/ddy062.

MYO9A deficiency in motor neurons is associated with reduced neuromuscular agrin secretion

Authors:
O’Connor E, Phan V, Cordts I, Cairns G, Hettwer S, Cox D, Lochmüller H, Roos A
Citation:
Hum Molec Genet. 2018;[Epub ahead of print] doi:10.1093/hmg/ddy054
Abstract:
Congenital myasthenic syndromes (CMS) are a group of rare, inherited disorders characterised by compromised function of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
O’Connor E, Phan V, Cordts I, Cairns G, Hettwer S, Cox D, Lochmüller H, Roos A. MYO9A deficiency in motor neurons is associated with reduced neuromuscular agrin secretion. Hum Molec Genet. 2018;[Epub ahead of print] doi:10.1093/hmg/ddy054.

Dicer inactivation stimulates limb regeneration ability in Xenopus laevis

Authors:
Zhang M, Yang L, Yuan F, Chen Y, Lin G
Citation:
Wound Repair Regen. 2018 Feb 17. doi: 10.1111/wrr.12619. [Epub ahead of print]
Abstract:
The ontogenetic decline of regeneration capacity in the anuran amphibian Xenopus makes it an excellent model for regeneration...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Zhang M, Yang L, Yuan F, Chen Y, Lin G. Dicer inactivation stimulates limb regeneration ability in Xenopus laevis. Wound Repair Regen. 2018 Feb 17. doi: 10.1111/wrr.12619. [Epub ahead of print].

Mutation of IFNLR1, an interferon lambda receptor 1, is associated with autosomal-dominant non-syndromic hearing loss

Authors:
Gao X, Yuan YY, Lin QF, Xu JC, Wang WQ, Qiao YH, Kang DY, Bai D, Xin F, Huang SS, Qiu SW, Guan LP, Su Y, Wang GJ, Han MY, Jiang Y, Liu HK, Dai P
Citation:
J Med Genet. 2018 Feb 16. pii: jmedgenet-2017-104954. doi: 10.1136/jmedgenet-2017-104954. [Epub ahead of print]
Abstract:
Background Hereditary sensorineural hearing loss is a genetically heterogeneous disorder.Objectives This study was designed to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao X, Yuan YY, Lin QF, Xu JC, Wang WQ, Qiao YH, Kang DY, Bai D, Xin F, Huang SS, Qiu SW, Guan LP, Su Y, Wang GJ, Han MY, Jiang Y, Liu HK, Dai P. Mutation of IFNLR1, an interferon lambda receptor 1, is associated with autosomal-dominant non-syndromic hearing loss. J Med Genet. 2018 Feb 16. pii: jmedgenet-2017-104954. doi: 10.1136/jmedgenet-2017-104954. [Epub ahead of print].

The absence of a novel intron 19-retaining ALK transcript (ALK-I19) and MYCN amplification correlates with an excellent clinical outcome in neuroblastoma patients

Authors:
Alshareef A, Irwin MS, Gupta N, Zhang H-F, Haque M, Findlay SD, Seong BKA, Lai J, Rayis M, Al-Dandan S, Lai R
Citation:
Oncotarget. 2018; 9:10698-713. doi:10.18632/oncotarget.24216
Abstract:
ALK missense mutations are detected in 8% of neuroblastoma (NB) tumors at diagnosis and confer gain-of-function oncogenic...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: human neuroblastoma cell lines
Citation Extract:
Alshareef A, Irwin MS, Gupta N, Zhang H-F, Haque M, Findlay SD, Seong BKA, Lai J, Rayis M, Al-Dandan S, Lai R. The absence of a novel intron 19-retaining ALK transcript (ALK-I19) and MYCN amplification correlates with an excellent clinical outcome in neuroblastoma patients. Oncotarget. 2018; 9:10698-713. doi:10.18632/oncotarget.24216.

Cystathionine β-Synthase Is Necessary for Axis Development in Vivo

Authors:
Prabhudesai S, Koceja1 C, Dey A, Eisa-Beygi S, Leigh NR, Bhattacharya R, Mukherjee P, Ramchandran R
Citation:
Front Cell Dev Biol. 2018;6:14. doi:10.3389/fcell.2018.00014
Abstract:
The cystathionine ß-synthase (CBS) is a critical enzyme in the transsulfuration pathway and is responsible for the synthesis of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prabhudesai S, Koceja1 C, Dey A, Eisa-Beygi S, Leigh NR, Bhattacharya R, Mukherjee P, Ramchandran R. Cystathionine β-Synthase Is Necessary for Axis Development in Vivo. Front Cell Dev Biol. 2018;6:14. doi:10.3389/fcell.2018.00014.

Tissue stiffening coordinates morphogenesis by triggering collective cell migration in vivo

Authors:
Barriga EH, Franze K, Charras G, Mayor R
Citation:
Nature. 2018 Feb 14. doi: 10.1038/nature25742. [Epub ahead of print]
Abstract:
Collective cell migration is essential for morphogenesis, tissue remodelling and cancer invasion. In vivo, groups of cells move...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Barriga EH, Franze K, Charras G, Mayor R. Tissue stiffening coordinates morphogenesis by triggering collective cell migration in vivo. Nature. 2018 Feb 14. doi: 10.1038/nature25742. [Epub ahead of print].

Forebrain Electrophysiological Recording in Larval Zebrafish

Authors:
Baraban SC
Citation:
J Vis Exp. 2013;(71):e50104. doi:10.3791/50104
Abstract:
Epilepsy affects nearly 3 million people in the United States and up to 50 million people worldwide. Defined as the occurrence...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baraban SC. Forebrain Electrophysiological Recording in Larval Zebrafish. J Vis Exp. 2013;(71):e50104. doi:10.3791/50104.

Visualization of Craniofacial Development in the sox10: kaede Transgenic Zebrafish Line Using Time-lapse Confocal Microscopy

Authors:
Gfrerer L, Dougherty M, Liao EC
Citation:
J Vis Exp. 2013;(79):e50525, doi:10.3791/50525
Abstract:
Vertebrate palatogenesis is a highly choreographed and complex developmental process, which involves migration of cranial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gfrerer L, Dougherty M, Liao EC. Visualization of Craniofacial Development in the sox10: kaede Transgenic Zebrafish Line Using Time-lapse Confocal Microscopy. J Vis Exp. 2013;(79):e50525, doi:10.3791/50525.

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