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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

The interaction of Pu.1 and cMyb in zebrafish neutrophil development

Authors:
Jia-Xin H, Song'en X, Wen-Qing Z, Wei L
Citation:
Yi Chuan. 2024 Apr 20;46(4):319-332. doi: 10.16288/j.yczz.23-312
Epub:
Not Epub
Abstract:
Granulopoiesis is a highly ordered and precisely regulated process in which hematopoietic-related transcription factors play...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jia-Xin H, Song'en X, Wen-Qing Z, Wei L. The interaction of Pu.1 and cMyb in zebrafish neutrophil development. Yi Chuan. 2024 Apr 20;46(4):319-332. doi: 10.16288/j.yczz.23-312.

Dysregulated lysosomal exocytosis drives protease-mediated cartilage pathogenesis in multiple lysosomal disorders

Authors:
Lee JJ, Wang T, Wiggins K, Lu PN, Underwood C, Ochenkowska K, Samarut E, Pollard LM, Flanagan-Steet H, Steet R
Citation:
iScience. 2024 Feb 21. doi.org/10.1016/j.isci.2024.109293
Epub:
Not Epub
Abstract:
The classic view of the lysosome as a static recycling center has been replaced with one of a dynamic and mobile hub of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee JJ, Wang T, Wiggins K, Lu PN, Underwood C, Ochenkowska K, Samarut E, Pollard LM, Flanagan-Steet H, Steet R. Dysregulated lysosomal exocytosis drives protease-mediated cartilage pathogenesis in multiple lysosomal disorders. iScience. 2024 Feb 21. doi.org/10.1016/j.isci.2024.109293.

ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells

Authors:
Heindl MR, Rupp A-L, Schwerdtner M, Bestle D, Harbig A, De Rocher A, Schmacke LC, Staker B, Steinmetzer T, Stein DA, Moulton HM, Böttcher-Friebertshäuser E
Citation:
J Virol. 2024 Apr 16;98(4):e0010224. doi: 10.1128/jvi.00102-24
Epub:
Not Epub
Abstract:
The transmembrane serine protease 2 (TMPRSS2) activates the outer structural proteins of a number of respiratory viruses...
Delivery Method:
(RXR)4 peptide-linked
Organism or Cell Type:
cell culture: Calu-3
Citation Extract:
Heindl MR, Rupp A-L, Schwerdtner M, Bestle D, Harbig A, De Rocher A, Schmacke LC, Staker B, Steinmetzer T, Stein DA, Moulton HM, Böttcher-Friebertshäuser E. ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells . J Virol. 2024 Apr 16;98(4):e0010224. doi: 10.1128/jvi.00102-24.

BAG6 inhibits influenza A virus replication by inducing viral polymerase subunit PB2 degradation and perturbing RdRp complex assembly

Authors:
Zhou Y, Li T, Zhang Y, Zhang N, Guo Y, Gao X, Peng W, Shu S, Zhao C, Cui D, Sun H, Sun Y, Liu J, Tang J, Zhang R, Pu J
Citation:
PLoS Pathog 20(3): e1012110. doi.org/10.1371/journal.ppat.1012110
Epub:
Not Epub
Abstract:
The interaction between influenza A virus (IAV) and host proteins is an important process that greatly influences viral...
Delivery Method:
intranasal peptide-linked
Organism or Cell Type:
BALB/c mice
Citation Extract:
Zhou Y, Li T, Zhang Y, Zhang N, Guo Y, Gao X, Peng W, Shu S, Zhao C, Cui D, Sun H, Sun Y, Liu J, Tang J, Zhang R, Pu J. BAG6 inhibits influenza A virus replication by inducing viral polymerase subunit PB2 degradation and perturbing RdRp complex assembly. PLoS Pathog 20(3): e1012110. doi.org/10.1371/journal.ppat.1012110.

Kinesin KIFC3 is essential for microtubule stability and cytokinesis in oocyte meiosis.

Authors:
Ju, JQ, Zhang, HL, Wang Y, Hu LL, Sun SC
Citation:
Cell Commun Signal 22, 199 (2024). doi.org/10.1186/s12964-024-01589-8
Epub:
Not Epub
Abstract:
KIFC3 is a member of Kinesin-14 family motor proteins, which play a variety of roles such as centrosome cohesion, cytokinesis,...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocysts
Citation Extract:
Ju, JQ, Zhang, HL, Wang Y, Hu LL, Sun SC. Kinesin KIFC3 is essential for microtubule stability and cytokinesis in oocyte meiosis.. Cell Commun Signal 22, 199 (2024). doi.org/10.1186/s12964-024-01589-8.

ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis.

Authors:
Hijaze E, Gildor T, Seidel R, Layous M, Winter M, Bertinetti L, Politi Y, Ben-Tabou de-Leon, S.
Citation:
eLife 12 (2024): RP89080. doi.org/10.7554/eLife.89080.4
Epub:
Not Epub
Abstract:
Biomineralization had apparently evolved independently in different phyla, using distinct minerals, organic scaffolds and gene...
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotous lividus (sea urchin)
Citation Extract:
Hijaze E, Gildor T, Seidel R, Layous M, Winter M, Bertinetti L, Politi Y, Ben-Tabou de-Leon, S.. ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis.. eLife 12 (2024): RP89080. doi.org/10.7554/eLife.89080.4.

Plexin B3 guides axons to cross the midline in vivo.

Authors:
Liu ZZ, Liu LY, Zhu LY, Zhu J, Luo JY, Wang YF, Xu HA.
Citation:
Front. Cell. Neurosci. 18:1292969. doi: 10.3389/fncel.2024.1292969
Epub:
Not Epub
Abstract:
During the development of neural circuits, axons are guided by a variety of molecular cues to navigate through the brain and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu ZZ, Liu LY, Zhu LY, Zhu J, Luo JY, Wang YF, Xu HA.. Plexin B3 guides axons to cross the midline in vivo.. Front. Cell. Neurosci. 18:1292969. doi: 10.3389/fncel.2024.1292969 .

Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges.

Authors:
Godavarthi SK, Hiramoto M, Ignatyev Y, Levin JB , Li H, Pratelli M, Borchardt J, Czajkowski C, Borodinsky LN, Sweeney L, Cline HT, Spitzer NC.
Citation:
PNAS. 2024 April 3. 121 (15) e2318041121. doi:10.1073/pnas.2318041121
Epub:
Not Epub
Abstract:
Stable matching of neurotransmitters with their receptors is fundamental to synapse function and reliable...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Godavarthi SK, Hiramoto M, Ignatyev Y, Levin JB , Li H, Pratelli M, Borchardt J, Czajkowski C, Borodinsky LN, Sweeney L, Cline HT, Spitzer NC.. Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges.. PNAS. 2024 April 3. 121 (15) e2318041121. doi:10.1073/pnas.2318041121.

Notch is Required for Neural Progenitor Proliferation During Embryonic Eye Regrowth.

Authors:
Guerin DJ, Gutierrez B, Zhang B, Ai-Sun Tseng KAS.
Citation:
bioRxiv 2024.01.31.577915; [preprint] doi.org/10.1101/2024.01.31.577915
Epub:
Not Epub
Abstract:
The ability of an organism to regrow tissues is regulated by various signaling pathways. One such pathway that has been studied...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Guerin DJ, Gutierrez B, Zhang B, Ai-Sun Tseng KAS.. Notch is Required for Neural Progenitor Proliferation During Embryonic Eye Regrowth.. bioRxiv 2024.01.31.577915; [preprint] doi.org/10.1101/2024.01.31.577915.

Cdx1 and Gsc distinctly regulate the transcription of BMP4 target gene ventx3.2 by directly binding to the proximal promoter region in Xenopus gastrulae.

Authors:
Shankar Goutam R, Kumar V, Lee U, Kim J.
Citation:
Molecules and Cells. Volume 47, Issue 4, 2024. doi.org/10.1016/j.mocell.2024.100058.
Epub:
Not Epub
Abstract:
A comprehensive regulatory network of transcription factors controls the dorsoventral patterning of the body axis in developing...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shankar Goutam R, Kumar V, Lee U, Kim J.. Cdx1 and Gsc distinctly regulate the transcription of BMP4 target gene ventx3.2 by directly binding to the proximal promoter region in Xenopus gastrulae.. Molecules and Cells. Volume 47, Issue 4, 2024. doi.org/10.1016/j.mocell.2024.100058..

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