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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 8437 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development

Authors:
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M
Citation:
Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15.
Abstract:
Arterial specification and differentiation are influenced by a number of regulatory pathways. While it is known that the Vegfa-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M. SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15..

Trim33 / Tif1-γ is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues

Authors:
Demy DL, Tauzin M, Lancino M, le Cabec V, Redd M, Murayama E, Maridonneau-Parini I, Trede N, Herbomel P
Citation:
J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.203471
Abstract:
Macrophages infiltrate and establish in developing organs from an early stage, often before these have become vascularised....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Demy DL, Tauzin M, Lancino M, le Cabec V, Redd M, Murayama E, Maridonneau-Parini I, Trede N, Herbomel P. Trim33 / Tif1-γ is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues. J Cell Sci. 2017;[Epub ahead of print] doi:10.1242/jcs.203471.

Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells

Authors:
Egesipe AL, Blondel S, Cicero AL, Jaskowiak AL, Navarro C, Sandre-Giovannoli A, Levy N, Peschanski M, Nissan X
Citation:
NPJ Aging Mech Dis. 2016 Nov 10;2:16026. doi: 10.1038/npjamd.2016.26. eCollection 2016
Abstract:
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder that causes systemic accelerated aging in children. This...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HGPS MSCs
Citation Extract:
Egesipe AL, Blondel S, Cicero AL, Jaskowiak AL, Navarro C, Sandre-Giovannoli A, Levy N, Peschanski M, Nissan X. Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells. NPJ Aging Mech Dis. 2016 Nov 10;2:16026. doi: 10.1038/npjamd.2016.26. eCollection 2016.

Dexamethasone-induced hepatomegaly and steatosis in larval zebrafish

Authors:
Yin G, Cao L, Du J, Jia R, Kitazawa T, Kubota A, Teraoka H
Citation:
J Toxicol Sci. 2017;42(4):455-459. doi: 10.2131/jts.42.455
Abstract:
Fish hepatobiliary syndrome, characterized by hepatomegaly and fatty liver, has been frequently reported in many cultured fish...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yin G, Cao L, Du J, Jia R, Kitazawa T, Kubota A, Teraoka H. Dexamethasone-induced hepatomegaly and steatosis in larval zebrafish. J Toxicol Sci. 2017;42(4):455-459. doi: 10.2131/jts.42.455.

Klf8 regulates left-right asymmetric patterning through modulation of Kupffer's vesicle morphogenesis and spaw expression

Authors:
Lin CY, Tsai MY, Liu YH, Lu YF, Chen YC, Lai YR, Liao HC, Lien HW, Yang CH, Huang CJ, Hwang SL
Citation:
J Biomed Sci. 2017 Jul 17;24(1):45. doi: 10.1186/s12929-017-0351-y
Abstract:
BACKGROUND: Although vertebrates are bilaterally symmetric organisms, their internal organs are distributed asymmetrically...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CY, Tsai MY, Liu YH, Lu YF, Chen YC, Lai YR, Liao HC, Lien HW, Yang CH, Huang CJ, Hwang SL. Klf8 regulates left-right asymmetric patterning through modulation of Kupffer's vesicle morphogenesis and spaw expression. J Biomed Sci. 2017 Jul 17;24(1):45. doi: 10.1186/s12929-017-0351-y.

Abscisic acid induces a transient shift in signaling that enhances NF-κB-mediated parasite killing in the midgut of Anopheles stephensi without reducing lifespan or fecundity

Authors:
Glennon EKK, Torrevillas BK, Morrissey SF, Ejercito JM, Luckhart S
Citation:
Parasit Vectors. 2017 Jul 13;10(1):333. doi: 10.1186/s13071-017-2276-4
Abstract:
BACKGROUND: Abscisic acid (ABA) is naturally present in mammalian blood and circulating levels can be increased by oral...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Anopheles stephensi (mosquito)
Citation Extract:
Glennon EKK, Torrevillas BK, Morrissey SF, Ejercito JM, Luckhart S. Abscisic acid induces a transient shift in signaling that enhances NF-κB-mediated parasite killing in the midgut of Anopheles stephensi without reducing lifespan or fecundity. Parasit Vectors. 2017 Jul 13;10(1):333. doi: 10.1186/s13071-017-2276-4.

Conserved gene regulatory module specifies lateral neural borders across bilaterians

Authors:
Li Y, Zhao D, Horie T, Chen G, Bao H, Chen S, Liu W, Horie R, Liang T, Dong B, Feng Q, Tao Q, Xiao Liu X
Citation:
Proc Natl Acad Sci USA. 2017;[Early Edition] doi:10.1073/pnas.1704194114
Abstract:
The lateral neural plate border (NPB), the neural part of the vertebrate neural border, is composed of central nervous system (...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Li Y, Zhao D, Horie T, Chen G, Bao H, Chen S, Liu W, Horie R, Liang T, Dong B, Feng Q, Tao Q, Xiao Liu X. Conserved gene regulatory module specifies lateral neural borders across bilaterians. Proc Natl Acad Sci USA. 2017;[Early Edition] doi:10.1073/pnas.1704194114.

A mutation in the LMOD1 actin-binding domain segregating with disease in a large British family with thoracic aortic aneurysms and dissections

Authors:
Wan YBA, Simpson MA, Aragon-Martin JA, Osborn DPS, Regalado ES, Guo D, Boileau C, Jondeau G, Benarroch L, Isekame Y, Bharj J, Sneddon J, Fisher EM, Dean J, Esteban MTT, Saggar A, Milewicz D, Jahangiri M, Behr ER, Smith A, Child AH
Citation:
bioRxiv. 2017;[preprint] doi:doi.org/10.1101/153452
Abstract:
We describe a mutation in LMOD1, which predisposes individuals to thoracic aortic aneurysms and dissections in a large multi-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wan YBA, Simpson MA, Aragon-Martin JA, Osborn DPS, Regalado ES, Guo D, Boileau C, Jondeau G, Benarroch L, Isekame Y, Bharj J, Sneddon J, Fisher EM, Dean J, Esteban MTT, Saggar A, Milewicz D, Jahangiri M, Behr ER, Smith A, Child AH. A mutation in the LMOD1 actin-binding domain segregating with disease in a large British family with thoracic aortic aneurysms and dissections. bioRxiv. 2017;[preprint] doi:doi.org/10.1101/153452 .

Endothelial Notch signalling limits angiogenesis via control of artery formation

Authors:
Hasan SS, Tsaryk R, Lange M, Wisniewski L, Moore JC, Lawson ND, Wojciechowska K, Schnittler H, Siekmann AF
Citation:
Nat Cell Biol. 2017;[Epub] doi:10.1038/ncb3574
Abstract:
Angiogenic sprouting needs to be tightly controlled. It has been suggested that the Notch ligand dll4 expressed in leading tip...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hasan SS, Tsaryk R, Lange M, Wisniewski L, Moore JC, Lawson ND, Wojciechowska K, Schnittler H, Siekmann AF. Endothelial Notch signalling limits angiogenesis via control of artery formation. Nat Cell Biol. 2017;[Epub] doi:10.1038/ncb3574.

microRNA-206 modulates an Rtn4a/Cxcr4a/Thbs3a axis in newly forming somites to maintain and stabilize the somite boundary formation of zebrafish embryos

Authors:
Lin CY, He JY, Zeng CW, Loo MR, Chang WY, Zhang PH, Tsai HJ
Citation:
Open Biol. 2017 Jul;7(7). pii: 170009. doi: 10.1098/rsob.170009
Abstract:
Although microRNA-206 (miR-206) is known to regulate proliferation and differentiation of muscle fibroblasts, the role of miR-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CY, He JY, Zeng CW, Loo MR, Chang WY, Zhang PH, Tsai HJ. microRNA-206 modulates an Rtn4a/Cxcr4a/Thbs3a axis in newly forming somites to maintain and stabilize the somite boundary formation of zebrafish embryos. Open Biol. 2017 Jul;7(7). pii: 170009. doi: 10.1098/rsob.170009.

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