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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Specification of the otic placode depends on Sox9 function in Xenopus

Authors:
Saint-Germain N, Lee YH, Zhang Y, Sargent TD, Saint-Jeannet JP
Citation:
Development. 2004 Apr;131(8):1755-63.
Epub:
Not Epub
Abstract:
The vertebrate inner ear develops from a thickening of the embryonic ectoderm, adjacent to the hindbrain, known as the otic...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Saint-Germain N, Lee YH, Zhang Y, Sargent TD, Saint-Jeannet JP. Specification of the otic placode depends on Sox9 function in Xenopus. Development. 2004 Apr;131(8):1755-63..

Tbx5-mediated expression of Ca(2+)/calmodulin-dependent protein kinase II is necessary for zebrafish cardiac and pectoral fin morphogenesis

Authors:
Rothschild SC, Easley CA 4th, Francescatto L, Lister JA, Garrity DM, Tombes RM
Citation:
Dev Biol. 2009 Apr 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mutations in the T-box transcription factor, TBX5, result in Holt-Oram syndrome (HOS), a human condition in which cardiac...
Organism or Cell Type:
zebrafish
Citation Extract:
Rothschild SC, Easley CA 4th, Francescatto L, Lister JA, Garrity DM, Tombes RM. Tbx5-mediated expression of Ca(2+)/calmodulin-dependent protein kinase II is necessary for zebrafish cardiac and pectoral fin morphogenesis. Dev Biol. 2009 Apr 1. [Epub ahead of print].

The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development

Authors:
Ruzov A, Savitskaya E, Hackett JA, Reddington JP, Prokhortchouk A, Madej MJ, Chekanov N, Li M, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR
Citation:
Development. 2009 Mar;136(5):729-38. Epub 2009 Jan 21
Epub:
Not Epub
Abstract:
Mammalian forms of the transcription repressor, Kaiso, can reportedly bind methylated DNA and non-methylated CTGCNA motifs....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ruzov A, Savitskaya E, Hackett JA, Reddington JP, Prokhortchouk A, Madej MJ, Chekanov N, Li M, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR. The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development. Development. 2009 Mar;136(5):729-38. Epub 2009 Jan 21.

The receptor protein-tyrosine phosphatase, Dep1, acts in arterial/venous cell fate decisions in zebrafish development

Authors:
Rodriguez F, Vacaru A, Overvoorde J, den Hertog J
Citation:
Dev Biol. 2008 Sep 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Dep1 is a transmembrane protein-tyrosine phosphatase (PTP) that is expressed in vascular endothelial cells and has tumor...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rodriguez F, Vacaru A, Overvoorde J, den Hertog J. The receptor protein-tyrosine phosphatase, Dep1, acts in arterial/venous cell fate decisions in zebrafish development. Dev Biol. 2008 Sep 23. [Epub ahead of print].

The u-boot mutation identifies a Hedgehog-regulated myogenic switch for fiber-type diversification in the zebrafish embryo

Authors:
Roy S, Wolff C, Ingham PW
Citation:
Genes Dev. 2001 Jun 15;15(12):1563-76
Epub:
Not Epub
Abstract:
Developmental programs that govern the embryonic diversification of distinct kinds of muscles in vertebrates remain obscure....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roy S, Wolff C, Ingham PW. The u-boot mutation identifies a Hedgehog-regulated myogenic switch for fiber-type diversification in the zebrafish embryo. Genes Dev. 2001 Jun 15;15(12):1563-76.

The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx

Authors:
Rodríguez-Seguel E, Alarcón P, Gómez-Skarmeta JL
Citation:
Dev Biol. 2009 Mar 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Iroquois (Irx) genes encode homeoproteins conserved during evolution. Vertebrate genomes contain six Irx genes organized in...
Organism or Cell Type:
Xenopus
Citation Extract:
Rodríguez-Seguel E, Alarcón P, Gómez-Skarmeta JL. The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx. Dev Biol. 2009 Mar 4. [Epub ahead of print].

The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish

Authors:
Sakaguchi T, Kikuchi Y, Kuroiwa A, Takeda H, Stainier DY
Citation:
Development. 2006 Oct;133(20):4063-72
Epub:
Not Epub
Abstract:
The roles of extra-embryonic tissues in early vertebrate body patterning have been extensively studied, yet we know little...
Organism or Cell Type:
zebrafish
Citation Extract:
Sakaguchi T, Kikuchi Y, Kuroiwa A, Takeda H, Stainier DY. The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish. Development. 2006 Oct;133(20):4063-72.

The Zebrafish Homologue of the Human DYT1 Dystonia Gene Is Widely Expressed in CNS Neurons but Non-Essential for Early Motor System Development

Authors:
Sager JJ, Torres GE, Burton EA
Citation:
PLoS ONE. 2012;7(9):e45175. doi:10.1371/journal.pone.0045175
Epub:
Not Epub
Abstract:
DYT1 dystonia is caused by mutation of the TOR1A gene, resulting in the loss of a single glutamic acid residue near the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sager JJ, Torres GE, Burton EA. The Zebrafish Homologue of the Human DYT1 Dystonia Gene Is Widely Expressed in CNS Neurons but Non-Essential for Early Motor System Development. PLoS ONE. 2012;7(9):e45175. doi:10.1371/journal.pone.0045175.

TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis

Authors:
Rojas-Rivera D, Armisén R, Colombo A, Martínez G, Eguiguren AL, Díaz A, Kiviluoto S, Rodríguez D, Patron M, Rizzuto R, Bultynck G, Concha ML, Sierralta J, Stutzin A, Hetz C
Citation:
Cell Death Differ. 2012 Jun;19(6):1013-26. doi: 10.1038/cdd.2011.189. Epub 2012 Jan 13.
Epub:
Not Epub
Abstract:
Transmembrane BAX inhibitor motif-containing (TMBIM)-6, also known as BAX-inhibitor 1 (BI-1), is an anti-apoptotic protein that...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rojas-Rivera D, Armisén R, Colombo A, Martínez G, Eguiguren AL, Díaz A, Kiviluoto S, Rodríguez D, Patron M, Rizzuto R, Bultynck G, Concha ML, Sierralta J, Stutzin A, Hetz C. TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis. Cell Death Differ. 2012 Jun;19(6):1013-26. doi: 10.1038/cdd.2011.189. Epub 2012 Jan 13..

TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species

Authors:
Roca FJ, Ramakrishnan L
Citation:
Cell. 2013 Apr 25;153(3):521-34. doi: 10.1016/j.cell.2013.03.022. Epub 2013 Apr 11
Epub:
Not Epub
Abstract:
Tumor Necrosis Factor (TNF) constitutes a critical host defense against tuberculosis but its excess is also implicated in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roca FJ, Ramakrishnan L. TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species. Cell. 2013 Apr 25;153(3):521-34. doi: 10.1016/j.cell.2013.03.022. Epub 2013 Apr 11.

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