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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Lgl2 executes its function as a tumor suppressor by regulating ErbB signaling in the zebrafish epidermis

Authors:
Reischauer S, Levesque MP, Nüsslein-Volhard C, Sonawane M
Citation:
PLoS Genet. 2009 Nov;5(11):e1000720. Epub 2009 Nov 13
Epub:
Not Epub
Abstract:
Changes in tissue homeostasis, acquisition of invasive cell characteristics, and tumor formation can often be linked to the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reischauer S, Levesque MP, Nüsslein-Volhard C, Sonawane M. Lgl2 executes its function as a tumor suppressor by regulating ErbB signaling in the zebrafish epidermis. PLoS Genet. 2009 Nov;5(11):e1000720. Epub 2009 Nov 13.

Lnx-2b restricts gsc expression to the dorsal mesoderm by limiting Nodal and Bozozok activity

Authors:
Ro H, Dawid IB
Citation:
Biochem Biophys Res Commun. 2010 Nov 26;402(4):626-30. Epub 2010 Oct 28
Epub:
Not Epub
Abstract:
Coordinated Nodal-related signals and Bozozok (Boz) activity are critical for the initial specification of dorsal mesoderm and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ro H, Dawid IB. Lnx-2b restricts gsc expression to the dorsal mesoderm by limiting Nodal and Bozozok activity. Biochem Biophys Res Commun. 2010 Nov 26;402(4):626-30. Epub 2010 Oct 28.

mc1r Pathway regulation of zebrafish melanosome dispersion

Authors:
Richardson J, Lundegaard PR, Reynolds NL, Dorin JR, Porteous DJ, Jackson IJ, Patton EE
Citation:
Zebrafish. 2008 Dec;5(4):289-95
Epub:
Not Epub
Abstract:
Zebrafish rapidly alter their pigmentation in response to environmental changes. For black melanocytes, this change is due to...
Organism or Cell Type:
zebrafish
Citation Extract:
Richardson J, Lundegaard PR, Reynolds NL, Dorin JR, Porteous DJ, Jackson IJ, Patton EE. mc1r Pathway regulation of zebrafish melanosome dispersion. Zebrafish. 2008 Dec;5(4):289-95.

Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes

Authors:
Renzi A, Demorrow S, Onori P, Carpino G, Mancinelli R, Meng F, Venter J, White M, Franchitto A, Francis H, Han Y, Ueno Y, Dusio G, Jensen KJ, Greene JJ, Glaser S, Gaudio E, Alpini G
Citation:
Hepatology. 2012 Oct 18. doi: 10.1002/hep.26105. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background & Aims: Secretin stimulates ductal secretion by interacting with secretin receptor (SR) activating cAMP⇒CFTR⇒Cl...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Rat
Citation Extract:
Renzi A, Demorrow S, Onori P, Carpino G, Mancinelli R, Meng F, Venter J, White M, Franchitto A, Francis H, Han Y, Ueno Y, Dusio G, Jensen KJ, Greene JJ, Glaser S, Gaudio E, Alpini G. Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes. Hepatology. 2012 Oct 18. doi: 10.1002/hep.26105. [Epub ahead of print].

Morpholino knockdown of lysyl oxidase impairs zebrafish development, and reflects some aspects of copper metabolism disorders

Authors:
Reynaud C, Baas D, Gleyzal C, Le Guellec D, Sommer P
Citation:
Matrix Biol. 2008 Jul;27(6):547-60. Epub 2008 Mar 26.
Epub:
Not Epub
Abstract:
Lysyl oxidase (LOX), a copper-dependent amine oxidase known in mammals to catalyze the cross-linking of collagen and elastin in...
Organism or Cell Type:
zebrafish
Citation Extract:
Reynaud C, Baas D, Gleyzal C, Le Guellec D, Sommer P. Morpholino knockdown of lysyl oxidase impairs zebrafish development, and reflects some aspects of copper metabolism disorders. Matrix Biol. 2008 Jul;27(6):547-60. Epub 2008 Mar 26..

Multiple interactions between maternally-activated signalling pathways control Xenopus nodal-related genes

Authors:
Rex M, Hilton E, Old R
Citation:
Int J Dev Biol. 2002 Mar;46(2):217-26
Epub:
Not Epub
Abstract:
We have investigated the induction of the six Xenopus nodal-related genes, Xnr1-Xnr6, by maternal determinants. The beta-...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Rex M, Hilton E, Old R. Multiple interactions between maternally-activated signalling pathways control Xenopus nodal-related genes. Int J Dev Biol. 2002 Mar;46(2):217-26.

Mutations in PYCR1 cause cutis laxa with progeroid features

Authors:
Reversade B, Escande-Beillard N, Dimopoulou A, Fischer B, Chng SC, Li Y, Shboul M, Tham PY, Kayserili H, Al-Gazali L, Shahwan M, Brancati F, Lee H, O'Connor BD, Kegler MS, Merriman B, Nelson SF, Masri A, Alkazaleh F, Guerra D, Ferrari P, Nanda A, Rajab A, Markie D, Gray M, Nelson J, Grix A, Sommer A, Savarirayan R, Janecke AR, Steichen E, Sillence D, Haußer I, Budde B, Nürnberg G, Nürnberg P, Seemann P, Kunkel D, Zambruno G, Dallapiccola B, Schuelke M, Robertson S, Hamamy H, Wollnik B, Van Maldergem L, Mundlos S, Kornak U
Citation:
Nat Genet. 2009 Sep;41(9):1016-21. Epub 2009 Aug 2
Epub:
Not Epub
Abstract:
Autosomal recessive cutis laxa (ARCL) describes a group of syndromal disorders that are often associated with a progeroid...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus and zebrafish
Citation Extract:
Reversade B, Escande-Beillard N, Dimopoulou A, Fischer B, Chng SC, Li Y, Shboul M, Tham PY, Kayserili H, Al-Gazali L, Shahwan M, Brancati F, Lee H, O'Connor BD, Kegler MS, Merriman B, Nelson SF, Masri A, Alkazaleh F, Guerra D, Ferrari P, Nanda A, Rajab A, Markie D, Gray M, Nelson J, Grix A, Sommer A, Savarirayan R, Janecke AR, Steichen E, Sillence D, Haußer I, Budde B, Nürnberg G, Nürnberg P, Seemann P, Kunkel D, Zambruno G, Dallapiccola B, Schuelke M, Robertson S, Hamamy H, Wollnik B, Van Maldergem L, Mundlos S, Kornak U. Mutations in PYCR1 cause cutis laxa with progeroid features. Nat Genet. 2009 Sep;41(9):1016-21. Epub 2009 Aug 2.

Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways

Authors:
Ridnour LA, Windhausen AN, Isenberg JS, Yeung N, Thomas DD, Vitek MP, Roberts DD, Wink DA
Citation:
Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16898-903. Epub 2007 Oct 17
Epub:
Not Epub
Abstract:
Matrix metalloproteinases (MMPs) are of central importance in the proteolytic remodeling of matrix and the generation of...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: ANA1 macrophage cell line
Citation Extract:
Ridnour LA, Windhausen AN, Isenberg JS, Yeung N, Thomas DD, Vitek MP, Roberts DD, Wink DA. Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16898-903. Epub 2007 Oct 17.

Nitric Oxide Synthase and Breast Cancer: Role of TIMP-1 in NO-mediated Akt Activation

Authors:
Ridnour LA, Barasch KM, Windhausen AN, Dorsey TH, Lizardo MM, Yfantis HG, Lee DH, Switzer CH, Cheng RYS, Heinecke JL, Brueggmann E, Hines HB, Khanna C, Glynn SA, Ambs S, Wink DA
Citation:
PLoS ONE. 2012;7(9): e44081. doi:10.1371/journal.pone.0044081
Epub:
Not Epub
Abstract:
Prediction of therapeutic response and cancer patient survival can be improved by the identification of molecular markers...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human breast cancer MDA-MB-231
Citation Extract:
Ridnour LA, Barasch KM, Windhausen AN, Dorsey TH, Lizardo MM, Yfantis HG, Lee DH, Switzer CH, Cheng RYS, Heinecke JL, Brueggmann E, Hines HB, Khanna C, Glynn SA, Ambs S, Wink DA. Nitric Oxide Synthase and Breast Cancer: Role of TIMP-1 in NO-mediated Akt Activation. PLoS ONE. 2012;7(9): e44081. doi:10.1371/journal.pone.0044081.

Organizer restriction through modulation of Bozozok stability by the E3 ubiquitin ligase Lnx-like

Authors:
Ro H, Dawid IB
Citation:
Nat Cell Biol. 2009 Aug 9. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The organizer anchors the primary embryonic axis, and balance between dorsal (organizer) and ventral domains is fundamental to...
Organism or Cell Type:
zebrafish
Citation Extract:
Ro H, Dawid IB. Organizer restriction through modulation of Bozozok stability by the E3 ubiquitin ligase Lnx-like. Nat Cell Biol. 2009 Aug 9. [Epub ahead of print].

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