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Photo-Morpholinos

IMPORTANT: Photo-Morpholinos are no longer a supported product.

Photo-Morpholino papers

Ivanova AS, Tereshina MB, Araslanova KR, Martynova NY, Zaraisky AG. The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration. Front Cell Dev Biol. 2021;9:738940. doi:10.3389/fcell.2021.738940


Hamilton AM, Borodinsky LN. Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration. bioRxiv. 2020;[preprint] doi:10.1101/2020.08.05.238139.


Suzuki N, Hirano K, Ogino H, Ochi H. Arid3a regulates nephric tubule regeneration via evolutionarily conserved regeneration signal-response enhancers. eLife. 2019;8:e43186 doi:10.7554/eLife.43186
Xenopus laevis


Chowdhury TA, Koceja C, Eisa-Beygi S, Kleinstiver BP, Kumar SN, Lin CW, Li K, Prabhudesai S, Joung JK, Ramchandran R. Temporal and Spatial Post-Transcriptional Regulation of Zebrafish Tie1 mRNA by Long Noncoding RNA During Brain Vascular Assembly. Arterioscler Thromb Vasc Biol. 2018 May 3. pii: ATVBAHA.118.310848. doi: 10.1161/ATVBAHA.118.310848. [Epub ahead of print]


Kwong EML, Ho JCH, Lau MCC, You M-S, Jiang Y-J, Tse WKF. Restoration of polr1c in early embryogenesis rescues the Type 3 Treacher Collins Syndrome facial malformation phenotype in zebrafish. Am J Pathol. 2017;[Epub ahead of print] doi:10.1016/j.ajpath.2017.10.004


Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH. PFKFB4 control of Akt signaling is essential for premigratory and migratory neural crest formation. Development. 2017 Oct 16. pii: dev.157644. doi: 10.1242/dev.157644. [Epub ahead of print]
Xenopus laevis


Gudipaty SA, Lindblom J, Loftus PD, Redd MJ, Edes K, Davey CF, Krishnegowda V, Rosenblatt J. Mechanical stretch triggers rapid epithelial cell division through Piezo1. Nature. 2017;[Epub ahead of print] doi:10.1038/nature21407


Houssin NS, Bharathan NK, Turner SD, Dickinson AJ. Role of JNK during buccopharyngeal membrane perforation, the last step of embryonic mouth formation. Dev Dyn. 2017 Feb;246(2):100-115. doi: 10.1002/dvdy.24470. Epub 2016 Dec 29.


Wei S, Dai M, Liu Z, Ma Y, Shang H, Cao Y, Wang Q. The guanine nucleotide exchange factor Net1 facilitates the specification of dorsal cell fates in zebrafish embryos by promoting maternal β-catenin activation. Cell Res. 2016;[Epub ahead of print] doi:10.1038/cr.2016.141


Yoo SK, Pascoe HG, Pereira T, Kondo S, Jacinto A, Zhang X, Hariharan IK. Plexins function in epithelial repair in both Drosophila and zebrafish. Nat Comm. 2016;7:12282. doi:10.1038/ncomms12282


George T. Eisenhoffer, Gloria Slattum, Oscar E. Ruiz, Hideo Otsuna, Chase D. Bryan, Justin Lopez, Daniel S. Wagner, Joshua L. Bonkowsky, Chi-Bin Chien, Richard I. Dorsky, Jody Rosenblatt. A toolbox to study epidermal cell types in zebrafish. J Cell Sci. 2016:[Epub ahead of print] doi: 10.1242/jcs.184341


Deng W, Farnham MM, Goldys EM, Mohammed S, Pilowsky PM. Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells. J Biomed Nanotechnol. 2015 Dec;11(12):2111-23.


Cabochette P, Vega-Lopez G, Bitard J, Parain K, Chemouny R, Masson C, Borday C, Hedderich M, Henningfeld KA, Locker M, Bronchain O, Perron M. YAP controls retinal stem cell DNA replication timing and genomic stability. Elife. 2015 Sep 22;4. doi: 10.7554/eLife.08488.
Xenopus embryos


Jayakumar MK, Bansal A, Li BN, Zhang Y. Mesoporous silica-coated upconversion nanocrystals for near infrared light-triggered control of gene expression in zebrafish. Nanomedicine (Lond). 2015 Apr;10(7):1051-61. doi: 10.2217/nnm.14.198.


Gu Y, Shea J, Slattum G, Firpo MA, Alexander M, Mulvihill SJ, Golubovskaya VM, Rosenblatt J. Defective apical extrusion signaling contributes to aggressive tumor hallmarks. Elife. 2015 Jan 26;4:e04069. doi: 10.7554/eLife.04069.


Salta E, Lau P, Sala Frigerio C, Coolen M, Bally-Cuif L, De Strooper B. A self-organizing miR-132/Ctbp2 circuit regulates bimodal notch signals and glial progenitor fate choice during spinal cord maturation. Dev Cell. 2014 Aug 25;30(4):423-36. doi: 10.1016/j.devcel.2014.07.006. Epub 2014 Aug 14.


Krock BL, Perkins BD. The Par-PrkC Polarity Complex Is Required for Cilia Growth in Zebrafish Photoreceptors. PLoS One. 2014 Aug 21;9(8):e104661. doi: 10.1371/journal.pone.0104661. eCollection 2014.


Goetz JG, Steed E, Ferreira RR, Roth S, Ramspacher C, Boselli F, Charvin G, Liebling M, Wyart C, Schwab Y, Vermot J. Endothelial Cilia Mediate Low Flow Sensing during Zebrafish Vascular Development. Cell Rep. 2014. doi:10.1016/j.celrep.2014.01.032


Lin C-Y, Chen J-S, Loo M-R, Hsiao C-C, Chang W-Y, Tsai H-J. MicroRNA-3906 Regulates Fast Muscle Differentiation through Modulating the Target Gene homer-1b in Zebrafish Embryos. PLoS ONE. 2013;8(7): e70187. doi:10.1371/journal.pone.0070187


Saxena A, Peng BN, Bronner ME. Sox10-dependent neural crest origin of olfactory microvillous neurons in zebrafish. eLife. 2013;2:e00336 doi:10.7554/eLife.00336


Wolf A, Ryu S. Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2. Development. 2013;140:1762-1773. doi:10.1242/dev.085357 .


Eisenhoffer GT, Loftus PD, Yoshigi M, Otsuna H, Chien CB, Morcos PA, Rosenblatt J. Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia. Nature. 2012 Apr 15;484(7395):546-9. doi: 10.1038/nature10999.


Discussion of Photo-Morpholino beta testing, posted by Philip Washbourne on The Node.

Tallafuss A, Gibson D, Morcos P, Li Y, Seredick S, Eisen J, Washbourne P. Turning gene function ON and OFF using sense and antisense photo-morpholinos in zebrafish. Development. 2012;139:1691-1699. doi:10.1242/dev.072702