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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents

Authors:
Oehlers SH, Flores MV, Okuda KS, Hall CJ, Crosier KE, Crosier PS
Citation:
Dev Dyn. 2011 Jan;240(1):288-98
Epub:
Not Epub
Abstract:
Inflammatory bowel disease (IBD) results from dysfunctional interactions between the intestinal immune system and microbiota,...
Organism or Cell Type:
zebrafish
Citation Extract:
Oehlers SH, Flores MV, Okuda KS, Hall CJ, Crosier KE, Crosier PS. A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents. Dev Dyn. 2011 Jan;240(1):288-98.

A genetic Xenopus laevis tadpole model to study lymphangiogenesis

Authors:
Ny A, Koch M, Schneider M, Neven E, Tong RT, Maity S, Fischer C, Plaisance S, Lambrechts D, Heligon C, Terclavers S, Ciesiolka M, Kalin R, Man WY, Senn I, Wyns S, Lupu F, Brandli A, Vleminckx K, Collen D, Dewerchin M, Conway EM, Moons L, Jain RK, Carmelie
Citation:
Nat Med. 2005 Sep;11(9):998-1004. Epub 2005 Aug 14.
Epub:
Not Epub
Abstract:
Lymph vessels control fluid homeostasis, immunity and metastasis. Unraveling the molecular basis of lymphangiogenesis has been...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ny A, Koch M, Schneider M, Neven E, Tong RT, Maity S, Fischer C, Plaisance S, Lambrechts D, Heligon C, Terclavers S, Ciesiolka M, Kalin R, Man WY, Senn I, Wyns S, Lupu F, Brandli A, Vleminckx K, Collen D, Dewerchin M, Conway EM, Moons L, Jain RK, Carmelie. A genetic Xenopus laevis tadpole model to study lymphangiogenesis. Nat Med. 2005 Sep;11(9):998-1004. Epub 2005 Aug 14..

A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation

Authors:
Nyholm MK, Abdelilah-Seyfried S, Grinblat Y
Citation:
J Cell Sci. 2009 May 26. [Epub ahead of print]
Epub:
Not Epub
Abstract:
During neurulation, vertebrate embryos form a neural tube (NT), the rudiment of the central nervous system. In mammals and...
Organism or Cell Type:
zebrafish
Citation Extract:
Nyholm MK, Abdelilah-Seyfried S, Grinblat Y. A novel genetic mechanism regulates dorsolateral hinge-point formation during zebrafish cranial neurulation. J Cell Sci. 2009 May 26. [Epub ahead of print].

A transgenic Xenopus laevis reporter model to study lymphangiogenesis

Authors:
Ny A, Vandevelde W, Hohensinner P, Beerens M, Geudens I, Diez-Juan A, Brepoels K, Plaisance S, Krieg PA, Langenberg T, Vinckier S, Luttun A, Carmeliet P, Dewerchin M
Citation:
Bio Open. 2013;[Epub ahead of print] doi:10.1242/bio.20134739
Epub:
Not Epub
Abstract:
The importance of the blood- and lymph vessels in the transport of essential fluids, gases, macromolecules and cells in...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ny A, Vandevelde W, Hohensinner P, Beerens M, Geudens I, Diez-Juan A, Brepoels K, Plaisance S, Krieg PA, Langenberg T, Vinckier S, Luttun A, Carmeliet P, Dewerchin M. A transgenic Xenopus laevis reporter model to study lymphangiogenesis. Bio Open. 2013;[Epub ahead of print] doi:10.1242/bio.20134739 .

Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori

Authors:
Nossa CW, Jain P, Tamilselvam B, Gupta VR, Chen LF, Schreiber V, Desnoyers S, Blanke SR
Citation:
Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19998-20003. Epub 2009 Nov 6
Epub:
Not Epub
Abstract:
Modification of eukaryotic proteins is a powerful strategy used by pathogenic bacteria to modulate host cells during infection...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: AGS cells infected with H. pylori 26695
Citation Extract:
Nossa CW, Jain P, Tamilselvam B, Gupta VR, Chen LF, Schreiber V, Desnoyers S, Blanke SR. Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19998-20003. Epub 2009 Nov 6.

Advanced glycation end products increase collagen-specific chaperone protein in mouse diabetic nephropathy

Authors:
Ohashi S, Abe H, Takahashi T, Yamamoto Y, Takeuchi M, Arai H, Nagata K, Kita T, Okamoto H, Yamamoto H, Doi T
Citation:
J Biol Chem. 2004 May 7;279(19):19816-23. Epub 2004 Mar 05.
Epub:
Not Epub
Abstract:
Advanced glycation end products (AGEs) appear to contribute to the diabetic complications. This study reports the inhibitory...
Organism or Cell Type:
cell culture: mouse glomerular mesangial cells
Citation Extract:
Ohashi S, Abe H, Takahashi T, Yamamoto Y, Takeuchi M, Arai H, Nagata K, Kita T, Okamoto H, Yamamoto H, Doi T. Advanced glycation end products increase collagen-specific chaperone protein in mouse diabetic nephropathy. J Biol Chem. 2004 May 7;279(19):19816-23. Epub 2004 Mar 05..

Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation

Authors:
Nuzzo F, Radu C, Baralle M, Spiezia L, Hackeng TM, Simioni P, Castoldi E
Citation:
Blood. 2013 Oct 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Antisense molecules are emerging as a powerful tool to correct splicing defects. Recently, we identified a homozygous deep-...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: primary megakaryocytes
Citation Extract:
Nuzzo F, Radu C, Baralle M, Spiezia L, Hackeng TM, Simioni P, Castoldi E. Antisense-based RNA therapy of factor V deficiency: in vitro and ex vivo rescue of a F5 deep-intronic splicing mutation. Blood. 2013 Oct 1. [Epub ahead of print].

B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo

Authors:
Okuda Y, Ogura E, Kondoh H, Kamachi Y
Citation:
PLoS Genet. 2010 May 6;6(5):e1000936
Epub:
Not Epub
Abstract:
The B1 SOX transcription factors SOX1/2/3/19 have been implicated in various processes of early embryogenesis. However, their...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Okuda Y, Ogura E, Kondoh H, Kamachi Y. B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo. PLoS Genet. 2010 May 6;6(5):e1000936.

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation

Authors:
Oliveira MI, Gonçalves CM, Pinto M, Fabre S, Santos AM, Lee SF, Castro MAA, Nunes RJ, Barbosa RR, Parnes JR, Yu C, Davis SJ, Moreira A, Bismuth G, Carmo AM
Citation:
Eur. J. Immunol. 2012 Jan;42(1):195-205. doi: 10.1002/eji.201040528. Epub 2011 Nov 28.
Epub:
Not Epub
Abstract:
The T lineage glycoprotein CD6 is generally considered to be a co-activator of T-cell activation. Here we demonstrate that CD6...
Delivery Method:
Electroporation (Amaxa)
Organism or Cell Type:
cell culture: human T lymphocytes
Citation Extract:
Oliveira MI, Gonçalves CM, Pinto M, Fabre S, Santos AM, Lee SF, Castro MAA, Nunes RJ, Barbosa RR, Parnes JR, Yu C, Davis SJ, Moreira A, Bismuth G, Carmo AM. CD6 attenuates early and late signaling events, setting thresholds for T-cell activation. Eur. J. Immunol. 2012 Jan;42(1):195-205. doi: 10.1002/eji.201040528. Epub 2011 Nov 28..

Chordin is required for the spemann organizer transplantation phenomenon in Xenopus embryos

Authors:
Oelgeschlager M, Kuroda H, Reversade B, De Robertis EM
Citation:
Dev Cell. 2003 Feb;4(2):219-30
Epub:
Not Epub
Abstract:
We analyzed the Chordin requirement in Xenopus development. Targeting of both chordin Xenopus laevis pseudoalleles with...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Oelgeschlager M, Kuroda H, Reversade B, De Robertis EM. Chordin is required for the spemann organizer transplantation phenomenon in Xenopus embryos. Dev Cell. 2003 Feb;4(2):219-30.

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