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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging
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Citation:
Sci. Transl. Med. 2011;3:106ra107 doi:10.1126/scitranslmed.3002847 Epub:
Not Epub Abstract:
Hutchinson-Gilford progeria syndrome (HGPS) is caused by a point mutation in the LMNA gene that activates a cryptic donor... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Osorio FG, Navarro CL, Cadiñanos J, López-Mejía IC, Quirós PM, Bartoli C, Rivera J, Tazi J, Guzmán G, Varela I, Depetris D, de Carlos F, Cobo J, Andrés V, Sandre-Giovannoli AD, Freije JM, Lévy N, López-Otín C. Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging. Sci. Transl. Med. 2011;3:106ra107 doi:10.1126/scitranslmed.3002847. |
Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing
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Citation:
Nucleic Acids Res. 2012 Nov 20. [Epub ahead of print] Epub:
Not Epub Abstract:
Adenosine-to-Inosine (A-to-I) RNA editing is a post-transcriptional mechanism, evolved to diversify the transcriptome in... Delivery Method:
Endo-Porter or electroporation Organism or Cell Type:
cell culture Citation Extract: Penn AC, Balik A, Greger IH. Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing. Nucleic Acids Res. 2012 Nov 20. [Epub ahead of print]. |
Suppression and Epigenetic Regulation of MiR-9 Contributes to Ethanol Teratology: Evidence from Zebrafish and Murine Fetal Neural Stem Cell Models
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Citation:
Alcohol Clin Exp Res. 2013 Jun 25. doi: 10.1111/acer.12139. [Epub ahead of print] Epub:
Not Epub Abstract:
BACKGROUND: Fetal alcohol exposure produces multiorgan defects, making it difficult to identify underlying etiological... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Pappalardo-Carter DL, Balaraman S, Sathyan P, Carter ES, Chen WJ, Miranda RC. Suppression and Epigenetic Regulation of MiR-9 Contributes to Ethanol Teratology: Evidence from Zebrafish and Murine Fetal Neural Stem Cell Models. Alcohol Clin Exp Res. 2013 Jun 25. doi: 10.1111/acer.12139. [Epub ahead of print]. |
Synthesis of 5-alkynylated uracil-morpholino monomers using Sonogashira coupling
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Citation:
Tetrahed Lett. 2012;53(32):4179-83. doi:10.1016/j.tetlet.2012.05.141 Epub:
Not Epub Abstract:
Sonogashira coupling of 5-iodo uracil–morpholino monomer with different terminal alkynes has been achieved for first time in... Citation Extract: Paul S, Nandi B, Pattanayak S, Sinha S. Synthesis of 5-alkynylated uracil-morpholino monomers using Sonogashira coupling. Tetrahed Lett. 2012;53(32):4179-83. doi:10.1016/j.tetlet.2012.05.141. |
Telomerase modulates Wnt signalling by association with target gene chromatin
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Citation:
Nature. 2009 Jul 2;460(7251):66-72 Epub:
Not Epub Abstract:
Stem cells are controlled, in part, by genetic pathways frequently dysregulated during human tumorigenesis. Either stimulation... Organism or Cell Type:
Xenopus laevis Citation Extract: Park JI, Venteicher AS, Hong JY, Choi J, Jun S, Shkreli M, Chang W, Meng Z, Cheung P, Ji H, McLaughlin M, Veenstra TD, Nusse R, McCrea PD, Artandi SE. Telomerase modulates Wnt signalling by association with target gene chromatin. Nature. 2009 Jul 2;460(7251):66-72. |
The ADAMTS18 gene is responsible for autosomal recessive early onset severe retinal dystrophy
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Citation:
Orphanet J Rare Dis. 2013, 8:16 doi:10.1186/1750-1172-8-16 Epub:
Not Epub Abstract:
Background Inherited retinal dystrophies, including Retinitis Pigmentosa and Leber Congenital Amaurosis among others, are a... Delivery Method:
Microinjection Organism or Cell Type:
medaka Citation Extract: Peluso I, Conte I, Testa F, Dharmalingam G, Pizzo M, Collin RWJ, Meola N, Barbato S, Mutarelli M, Ziviello C, Barbarulo AM, Nigro V, Melone MAB, Simonelli F, Banfi S. The ADAMTS18 gene is responsible for autosomal recessive early onset severe retinal dystrophy. Orphanet J Rare Dis. 2013, 8:16 doi:10.1186/1750-1172-8-16. |
The Alzheimer-related gene presenilin-1 facilitates sonic hedgehog expression in Xenopus primary neurogenesis
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Citation:
Mech Dev 2001 Sep;107(1-2):119-31 Epub:
Not Epub Abstract:
We analyzed the influence of presenilins on the genetic cascades that control neuronal differentiation in Xenopus embryos.... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Paganelli AR, Ocana OH, Prat MI, Franco PG, Lopez SL, Morelli L, Adamo AM, Riccomagno MM, Matsubara E, Shoji M, Affranchino JL, Castano EM, Carrasco AE. The Alzheimer-related gene presenilin-1 facilitates sonic hedgehog expression in Xenopus primary neurogenesis. Mech Dev 2001 Sep;107(1-2):119-31. |
The Aplnr GPCR regulates myocardial progenitor development via a novel cell-non-autonomous, Gαi/o protein-independent pathway
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Citation:
Biology Open. 2012;1:275-285. doi:10.1242/bio.2012380 Epub:
Not Epub Abstract:
Myocardial progenitor development involves the migration of cells to the anterior lateral plate mesoderm (ALPM) where they are... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Paskaradevan S, Scott IC. The Aplnr GPCR regulates myocardial progenitor development via a novel cell-non-autonomous, Gαi/o protein-independent pathway. Biology Open. 2012;1:275-285. doi:10.1242/bio.2012380 . |
The Art and Design of Genetic Screens: Zebrafish
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Citation:
Nat Rev Genet. 2001 Dec;2(12):956-66. Epub:
Not Epub Abstract:
Inventive genetic screens in zebrafish are revealing new genetic pathways that control vertebrate development, disease and... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Patton EE, Zon LI. The Art and Design of Genetic Screens: Zebrafish. Nat Rev Genet. 2001 Dec;2(12):956-66.. |
The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation
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Citation:
Nature. 2004 Apr 15;428(6984):754-8 Epub:
Not Epub Abstract:
Vascular development is a complex but orderly process that is tightly regulated. A number of secreted factors produced by... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Parker LH, Schmidt M, Jin SW, Gray AM, Beis D, Pham T, Frantz G, Palmieri S, Hillan K, Stainier DY, De Sauvage FJ, Ye W. The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation. Nature. 2004 Apr 15;428(6984):754-8. |