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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Real-Time Whole-Body Visualization of Chikungunya Virus Infection and Host Interferon Response in Zebrafish

Authors:
Palha N, Guivel-Benhassine F, Briolat V, Lutfalla G, Sourisseau M, Ellett F, Wang C-H, Lieschke GJ, Herbomel P, Schwartz O, Levraud J-P
Citation:
PLoS Pathog. 2013;9(9):e1003619. doi:10.1371/journal.ppat.1003619
Epub:
Not Epub
Abstract:
Chikungunya Virus (CHIKV), a re-emerging arbovirus that may cause severe disease, constitutes an important public health...
Link:
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003619
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Palha N, Guivel-Benhassine F, Briolat V, Lutfalla G, Sourisseau M, Ellett F, Wang C-H, Lieschke GJ, Herbomel P, Schwartz O, Levraud J-P. Real-Time Whole-Body Visualization of Chikungunya Virus Infection and Host Interferon Response in Zebrafish. PLoS Pathog. 2013;9(9):e1003619. doi:10.1371/journal.ppat.1003619.

Redefining the initiation and maintenance of zebrafish interrenal steroidogenesis by characterizing the key enzyme Cyp11a2

Authors:
Parajes S, Griffin A, Taylor AE, Rose IT, Miguel-Escalada I, Hadzhiev Y, Arlt W, Shackleton C, Müller F, Krone N
Citation:
Endocrinology. 2013 May 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Zebrafish are emerging as a model to study steroid hormone action and associated disease. However, steroidogenesis in zebrafish...
Organism or Cell Type:
zebrafish
Citation Extract:
Parajes S, Griffin A, Taylor AE, Rose IT, Miguel-Escalada I, Hadzhiev Y, Arlt W, Shackleton C, Müller F, Krone N. Redefining the initiation and maintenance of zebrafish interrenal steroidogenesis by characterizing the key enzyme Cyp11a2. Endocrinology. 2013 May 13. [Epub ahead of print].

Reduced expression of CD45 protein tyrosine phosphatase provides protection against anthrax pathogenesis

Authors:
Panchal RG, Ulrich RL, Bradfute SB, Lane D, Ruthel G, Kenny TA, Iversen PL, Anderson AO, Gussio R, Raschke WC, Bavari S
Citation:
J Biol Chem. 2009 May 8;284(19):12874-85. Epub 2009 Mar 6.
Epub:
Not Epub
Abstract:
The modulation of cellular processes by small molecule inhibitors, gene inactivation or targeted knock-down strategies combined...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice and cell culture: macrophage J774A.1 cells
Citation Extract:
Panchal RG, Ulrich RL, Bradfute SB, Lane D, Ruthel G, Kenny TA, Iversen PL, Anderson AO, Gussio R, Raschke WC, Bavari S. Reduced expression of CD45 protein tyrosine phosphatase provides protection against anthrax pathogenesis. J Biol Chem. 2009 May 8;284(19):12874-85. Epub 2009 Mar 6..

Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2

Authors:
Pannicke U, Hönig M, Hess I, Friesen C, Holzmann K, Rump EM, Barth TF, Rojewski MT, Schulz A, Boehm T, Friedrich W, Schwarz K
Citation:
Nat Genet. 2009 Jan;41(1):101-5. Epub 2008 Nov 30
Epub:
Not Epub
Abstract:
Human severe combined immunodeficiencies (SCID) are phenotypically and genotypically heterogeneous diseases. Reticular...
Organism or Cell Type:
zebrafish
Citation Extract:
Pannicke U, Hönig M, Hess I, Friesen C, Holzmann K, Rump EM, Barth TF, Rojewski MT, Schulz A, Boehm T, Friedrich W, Schwarz K. Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2. Nat Genet. 2009 Jan;41(1):101-5. Epub 2008 Nov 30.

Role of Chd7 in Zebrafish: A Model for CHARGE Syndrome

Authors:
Patten SA, Jacobs-McDaniels NL, Zaouter C, Drapeau P, Albertson RC, Moldovan F
Citation:
PLoS ONE. 2012;7(2):e31650. doi:10.1371/journal.pone.0031650
Epub:
Not Epub
Abstract:
CHARGE syndrome is caused by mutations in the CHD7 gene. Several organ systems including the retina, cranial nerves, inner ear...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patten SA, Jacobs-McDaniels NL, Zaouter C, Drapeau P, Albertson RC, Moldovan F. Role of Chd7 in Zebrafish: A Model for CHARGE Syndrome. PLoS ONE. 2012;7(2):e31650. doi:10.1371/journal.pone.0031650.

Role of G protein-coupled estrogen receptor 1, GPER, in inhibition of oocyte maturation by endogenous estrogens in zebrafish

Authors:
Pang Y, Thomas P
Citation:
Dev Biol. 2010 Jun 15;342(2):194-206. Epub 2010 Apr 9
Epub:
Not Epub
Abstract:
Estrogen inhibition of oocyte maturation (OM) and the role of GPER (formerly known as GPR30) were investigated in zebrafish....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pang Y, Thomas P. Role of G protein-coupled estrogen receptor 1, GPER, in inhibition of oocyte maturation by endogenous estrogens in zebrafish. Dev Biol. 2010 Jun 15;342(2):194-206. Epub 2010 Apr 9.

Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling

Authors:
Park DS, Seo JH, Hong M, Choi SC
Citation:
Biochem Biophys Res Commun. 2013 Jun 3. doi:pii: S0006-291X(13)00911-X. 10.1016/j.bbrc.2013.05.104. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The Wnt/β-catenin signaling pathway plays critical roles in early embryonic development, stem cell biology and human diseases...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Park DS, Seo JH, Hong M, Choi SC. Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling. Biochem Biophys Res Commun. 2013 Jun 3. doi:pii: S0006-291X(13)00911-X. 10.1016/j.bbrc.2013.05.104. [Epub ahead of print].

Role of X-Delta-2 in the early neural development of Xenopus laevis

Authors:
Peres JN, Durston AJ
Citation:
Dev Dyn. 2006 Mar;235(3):802-10.
Epub:
Not Epub
Abstract:
The Drosophila Delta gene and its vertebrate homologues are ligands for the Notch receptor and are involved in a variety of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Peres JN, Durston AJ. Role of X-Delta-2 in the early neural development of Xenopus laevis. Dev Dyn. 2006 Mar;235(3):802-10..

Scl is required for dorsal aorta as well as blood formation in zebrafish embryos

Authors:
Patterson LJ, Gering M, Patient R
Citation:
Blood. 2005; 105(9): p. 3502-3511
Epub:
Not Epub
Abstract:
Blood and endothelial cells arise in close association in developing embryos, possibly from a shared precursor, the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patterson LJ, Gering M, Patient R. Scl is required for dorsal aorta as well as blood formation in zebrafish embryos. Blood. 2005; 105(9): p. 3502-3511.

Sesn1 is a novel gene for left-right asymmetry and mediating nodal signaling.

Authors:
Peeters H, Voz ML, Verschueren K, De Cat B, Pendeville H, Thienpont B, Schellens A, Belmont JW, David G, Van De Ven WJ, Fryns JP, Gewillig M, Huylebroeck D, Peers B, Devriendt K.
Citation:
Hum Mol Genet. 2006 Nov 15;15(22):3369-77. Epub 2006 Oct 12.
Epub:
Not Epub
Abstract:
Remarkable progress has been made in understanding the molecular mechanisms underlying left-right asymmetry in vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peeters H, Voz ML, Verschueren K, De Cat B, Pendeville H, Thienpont B, Schellens A, Belmont JW, David G, Van De Ven WJ, Fryns JP, Gewillig M, Huylebroeck D, Peers B, Devriendt K.. Sesn1 is a novel gene for left-right asymmetry and mediating nodal signaling.. Hum Mol Genet. 2006 Nov 15;15(22):3369-77. Epub 2006 Oct 12..

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