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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Knockdown of FoxO3a induces increased neuronal apoptosis during embryonic development in zebrafish

Authors:
Peng K, Li Y, Long L, Li D, Jia Q, Wang Y, Shen Q, Tang Y, Wen L, Kung HF, Peng Y
Citation:
Neurosci Lett. 2010 Oct 29;484(2):98-103. Epub 2010 Jul 30.
Epub:
Not Epub
Abstract:
Neuronal apoptosis sculpts the developing brain, and nearly all identified classes of neurons seem to be produced \"in...
Organism or Cell Type:
zebrafish
Citation Extract:
Peng K, Li Y, Long L, Li D, Jia Q, Wang Y, Shen Q, Tang Y, Wen L, Kung HF, Peng Y. Knockdown of FoxO3a induces increased neuronal apoptosis during embryonic development in zebrafish. Neurosci Lett. 2010 Oct 29;484(2):98-103. Epub 2010 Jul 30..

L-Leucine improves anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q)MDS by activating the mTOR pathway

Authors:
Payne E, Virgilio M, Narla A, Sun H, Levine M, Paw BH, Berliner N, Look AT, Ebert B, Khanna-Gupta A
Citation:
Blood. 2012 Jun 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Haploinsufficiency of ribosomal proteins (RP) has been proposed to be the common basis for the anemia observed in Diamond-...
Organism or Cell Type:
zebrafish
Citation Extract:
Payne E, Virgilio M, Narla A, Sun H, Levine M, Paw BH, Berliner N, Look AT, Ebert B, Khanna-Gupta A. L-Leucine improves anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q)MDS by activating the mTOR pathway. Blood. 2012 Jun 25. [Epub ahead of print].

Lens development depends on a pair of highly conserved Sox21 regulatory elements

Authors:
Pauls S, Smith SF, Elgar G
Citation:
Dev Biol. 2012 Feb 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Highly conserved non-coding elements (CNEs) linked to genes involved in embryonic development have been hypothesised to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pauls S, Smith SF, Elgar G. Lens development depends on a pair of highly conserved Sox21 regulatory elements. Dev Biol. 2012 Feb 24. [Epub ahead of print].

Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists

Authors:
Peng G, Westerfield M
Citation:
Development. 2006 Aug;133(16):3191-200. Epub 2006 Jul 19
Epub:
Not Epub
Abstract:
In vertebrate embryos, induction and patterning of the forebrain require the local inhibition of caudalizing signals, such as...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peng G, Westerfield M. Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists. Development. 2006 Aug;133(16):3191-200. Epub 2006 Jul 19.

Lithium bromide–DBU mediated synthesis of chlorophosphoramidate-activated morpholino nucleoside subunits

Authors:
Pattanayak S, Sinha S
Citation:
Tetrahedron Lett. 2012;53(49):6714-6717. doi:10.1016/j.tetlet.2012.09.126
Epub:
Not Epub
Abstract:
An efficient and rapid protocol for the synthesis of chlorophosphoramidate-activated morpholino subunits has been developed. A...
Citation Extract:
Pattanayak S, Sinha S. Lithium bromide–DBU mediated synthesis of chlorophosphoramidate-activated morpholino nucleoside subunits. Tetrahedron Lett. 2012;53(49):6714-6717. doi:10.1016/j.tetlet.2012.09.126.

Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo

Authors:
Peri F, Nüsslein-Volhard C
Citation:
Cell. 2008 May 30;133(5):916-27
Epub:
Not Epub
Abstract:
A significant proportion of neurons in the brain undergo programmed cell death. In order to prevent the diffusion of damaging...
Organism or Cell Type:
zebrafish
Citation Extract:
Peri F, Nüsslein-Volhard C. Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo. Cell. 2008 May 30;133(5):916-27.

LKB1 (XEEK1) regulates Wnt signalling in vertebrate development

Authors:
Ossipova O, Bardeesy N, DePinho RA, Green JB
Citation:
Nat Cell Biol. 2003 Oct;5(10):889-94. Epub 2003 Sep 14
Epub:
Not Epub
Abstract:
Germline LKB1/STK11 mutations are associated with the cancer-prone Peutz-Jeghers syndrome (PJS) in humans, and nullizygosity...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Ossipova O, Bardeesy N, DePinho RA, Green JB. LKB1 (XEEK1) regulates Wnt signalling in vertebrate development. Nat Cell Biol. 2003 Oct;5(10):889-94. Epub 2003 Sep 14.

Long-term consequences of Sox9 depletion on inner ear development

Authors:
Park BY, Saint-Jeannet JP
Citation:
Dev Dyn. 2010 Apr;239(4):1102-12.
Epub:
Not Epub
Abstract:
The transcription factor Sox9 has been implicated in inner ear formation in several species. To investigate the long-term...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Park BY, Saint-Jeannet JP. Long-term consequences of Sox9 depletion on inner ear development. Dev Dyn. 2010 Apr;239(4):1102-12..

Low-molecular-weight protein tyrosine phosphatase is a positive component of the fibroblast growth factor receptor signaling pathway

Authors:
Park EK, Warner N, Mood K, Pawson T, Daar IO
Citation:
Mol Cell Biol. 2002 May;22(10):3404-14
Epub:
Not Epub
Abstract:
Low-molecular-weight protein tyrosine phosphatase (LMW-PTP) has been implicated in the regulation of cell growth and actin...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC133800/
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Park EK, Warner N, Mood K, Pawson T, Daar IO. Low-molecular-weight protein tyrosine phosphatase is a positive component of the fibroblast growth factor receptor signaling pathway. Mol Cell Biol. 2002 May;22(10):3404-14.

Major vault protein promotes locomotor recovery and regeneration after spinal cord injury in adult zebrafish

Authors:
Pan HC, Lin JF, Ma LP, Shen YQ, Schachner M
Citation:
Eur J Neurosci. 2012;[Epub ahead of print] doi:10.1111/ejn.12038
Epub:
Not Epub
Abstract:
In contrast to mammals, adult zebrafish recover locomotor functions after spinal cord injury (SCI), in part due to axonal...
Organism or Cell Type:
zebrafish
Citation Extract:
Pan HC, Lin JF, Ma LP, Shen YQ, Schachner M. Major vault protein promotes locomotor recovery and regeneration after spinal cord injury in adult zebrafish. Eur J Neurosci. 2012;[Epub ahead of print] doi:10.1111/ejn.12038.

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