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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness

Authors:
Peachey NS, Ray TA, Florijn R, Rowe LB, Sjoerdsma T, Contreras-Alcantara S, Baba K, Tosini G, Pozdeyev N, Iuvone PM, Bojang P Jr, Pearring JN, Simonsz HJ, van Genderen M, Birch DG, Traboulsi EI, Dorfman A, Lopez I, Ren H, Goldberg AF, Nishina PM, Lachapelle P, McCall MA, Koenekoop RK, Bergen AA, Kamermans M, Gregg RG.
Citation:
Am J Hum Genet. 2012 Feb 10;90(2):331-9
Epub:
Not Epub
Abstract:
Complete congenital stationary night blindness (cCSNB) is a clinically and genetically heterogeneous group of retinal disorders...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peachey NS, Ray TA, Florijn R, Rowe LB, Sjoerdsma T, Contreras-Alcantara S, Baba K, Tosini G, Pozdeyev N, Iuvone PM, Bojang P Jr, Pearring JN, Simonsz HJ, van Genderen M, Birch DG, Traboulsi EI, Dorfman A, Lopez I, Ren H, Goldberg AF, Nishina PM, Lachapelle P, McCall MA, Koenekoop RK, Bergen AA, Kamermans M, Gregg RG.. GPR179 is required for depolarizing bipolar cell function and is mutated in autosomal-recessive complete congenital stationary night blindness. Am J Hum Genet. 2012 Feb 10;90(2):331-9.

Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory element binding protein activation

Authors:
Passeri MJ, Cinaroglu A, Gao C, Sadler KC
Citation:
Hepatology. 2009 Feb;49(2):443-52.
Epub:
Not Epub
Abstract:
Steatosis is the most common consequence of acute alcohol abuse and may predispose to more severe hepatic disease. Increased...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Passeri MJ, Cinaroglu A, Gao C, Sadler KC. Hepatic steatosis in response to acute alcohol exposure in zebrafish requires sterol regulatory element binding protein activation. Hepatology. 2009 Feb;49(2):443-52..

Hindbrain-derived Wnt and Fgf signals cooperate to specify the otic placode in Xenopus

Authors:
Park BY, Saint-Jeannet JP
Citation:
Dev Biol. 2008 Dec 1;324(1):108-21. Epub 2008 Sep 19
Epub:
Not Epub
Abstract:
Induction of the otic placode, the rudiment of the inner ear, is believed to depend on signals derived from surrounding tissues...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Park BY, Saint-Jeannet JP. Hindbrain-derived Wnt and Fgf signals cooperate to specify the otic placode in Xenopus. Dev Biol. 2008 Dec 1;324(1):108-21. Epub 2008 Sep 19.

Identification of common and unique modifiers of zebrafish midline bifurcation and cyclopia

Authors:
Pei W, Feldman B
Citation:
Dev Biol. 2009 Feb 1;326(1):201-11. Epub 2008 Nov 19
Epub:
Not Epub
Abstract:
Loss of the zebrafish Nodal-related protein Squint causes a spectrum of phenotypes including cyclopia and midline bifurcations...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pei W, Feldman B. Identification of common and unique modifiers of zebrafish midline bifurcation and cyclopia. Dev Biol. 2009 Feb 1;326(1):201-11. Epub 2008 Nov 19.

Improved Protocol for the Synthesis of Flexibly Protected Morpholino Monomers from Unprotected Ribonucleosides

Authors:
Pattanayak S, Paul S, Nandi B, Sinha S
Citation:
Nucleosides, Nucleotides and Nucleic Acids. 2012;31(11):763-82 doi:10.1080/15257770.2012.724491
Epub:
Not Epub
Abstract:
An inexpensive and much improved protocol has been developed for the synthesis of protected morpholino monomers from...
Citation Extract:
Pattanayak S, Paul S, Nandi B, Sinha S. Improved Protocol for the Synthesis of Flexibly Protected Morpholino Monomers from Unprotected Ribonucleosides. Nucleosides, Nucleotides and Nucleic Acids. 2012;31(11):763-82 doi:10.1080/15257770.2012.724491.

Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers

Authors:
Paessler S, Rijnbrand R, Stein DA, Ni H, Yun NE, Dziuba N, Borisevich V, Seregin A, Ma Y, Blouch R, Iversen PL, Zacks MA
Citation:
Virology. 2008 Jul 5;376(2):357-70. Epub 2008 May 12.
Epub:
Not Epub
Abstract:
The genus Alphavirus contains members that threaten human health, both as natural pathogens and as potential biological weapons...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice
Citation Extract:
Paessler S, Rijnbrand R, Stein DA, Ni H, Yun NE, Dziuba N, Borisevich V, Seregin A, Ma Y, Blouch R, Iversen PL, Zacks MA. Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers. Virology. 2008 Jul 5;376(2):357-70. Epub 2008 May 12..

Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

Authors:
Pera EM, Ikeda A, Eivers E, De Robertis EM
Citation:
Genes Dev. 2003 Dec 15;17(24):3023-8.
Epub:
Not Epub
Abstract:
How do very diverse signaling pathways induce neural differentiation in Xenopus? Anti-BMP (Chordin), FGF8, and IGF2 signals are...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pera EM, Ikeda A, Eivers E, De Robertis EM. Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. Genes Dev. 2003 Dec 15;17(24):3023-8..

Interaction between X-Delta-2 and Hox genes regulates segmentation and patterning of the anteroposterior axis

Authors:
Peres JN, McNulty CL, Durston AJ
Citation:
Mech Dev. 2006 Apr;123(4):321-33. Epub 2006 Apr 27.
Epub:
Not Epub
Abstract:
In vertebrates, the paraxial mesoderm already exhibits a complex Hox gene pattern by the time that segmentation occurs and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Peres JN, McNulty CL, Durston AJ. Interaction between X-Delta-2 and Hox genes regulates segmentation and patterning of the anteroposterior axis. Mech Dev. 2006 Apr;123(4):321-33. Epub 2006 Apr 27..

Isolation of a ventricle-specific promoter for the zebrafish ventricular myosin heavy chain (vmhc) gene and its regulation by GATA factors during embryonic heart development

Authors:
Park JS, Kim HS, Kim JD, Seo J, Chung KS, Lee HS, Huh TL, Jo I, Kim YO
Citation:
Dev Dyn. 2009 May 13;238(6):1574-1581. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We investigated chamber-specific gene expression by isolating a 2.2-kb polymerase chain reaction product containing the 5...
Organism or Cell Type:
zebrafish
Citation Extract:
Park JS, Kim HS, Kim JD, Seo J, Chung KS, Lee HS, Huh TL, Jo I, Kim YO. Isolation of a ventricle-specific promoter for the zebrafish ventricular myosin heavy chain (vmhc) gene and its regulation by GATA factors during embryonic heart development. Dev Dyn. 2009 May 13;238(6):1574-1581. [Epub ahead of print].

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

Authors:
Peng JC, Valouev A, Swigut T, Zhang J, Zhao Y, Sidow A, Wysocka J
Citation:
Cell. 2009 Dec 24;139(7):1290-302
Epub:
Not Epub
Abstract:
Polycomb Repressive Complex 2 (PRC2) regulates key developmental genes in embryonic stem (ES) cells and during development....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Peng JC, Valouev A, Swigut T, Zhang J, Zhao Y, Sidow A, Wysocka J. Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells. Cell. 2009 Dec 24;139(7):1290-302.

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