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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
Microarray profiling reveals CXCR4a is downregulated by blood flow in vivo and mediates collateral formation in zebrafish embryos
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Citation:
Physiol Genomics. 2009 Jun 9. [Epub ahead of print] Epub:
Not Epub Abstract:
The response to hemodynamic force is implicated in a number of pathologies including collateral vessel development. However,... Organism or Cell Type:
zebrafish Citation Extract: Packham IM, Gray C, Heath PR, Hellewell PG, Ingham PW, Crossman DC, Milo M, Chico TJ. Microarray profiling reveals CXCR4a is downregulated by blood flow in vivo and mediates collateral formation in zebrafish embryos. Physiol Genomics. 2009 Jun 9. [Epub ahead of print]. |
miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo
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Citation:
Mol Cell Biol. 2010 Jul;30(14):3620-34. Epub 2010 May 17 Epub:
Not Epub Abstract:
The lymphatic vascular system maintains tissue fluid homeostasis, helps mediate afferent immune responses, and promotes cancer... Delivery Method:
Microinjection Organism or Cell Type:
Zebrafish and Xenopus laevis Citation Extract: Pedrioli DM, Karpanen T, Dabouras V, Jurisic G, van de Hoek G, Shin JW, Marino D, Kälin RE, Leidel S, Cinelli P, Schulte-Merker S, Brändli AW, Detmar M. miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo. Mol Cell Biol. 2010 Jul;30(14):3620-34. Epub 2010 May 17. |
miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2
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Citation:
Blood. 2009 Feb 19;113(8):1794-804. Epub 2008 Oct 10. Epub:
Not Epub Abstract:
We demonstrate that in zebrafish the microRNA miR-451 plays a crucial role in promoting erythroid maturation, in part via its... Organism or Cell Type:
zebrafish Citation Extract: Pase L, Layton JE, Kloosterman WP, Carradice D, Waterhouse PM, Lieschke GJ. miR-451 regulates zebrafish erythroid maturation in vivo via its target gata2. Blood. 2009 Feb 19;113(8):1794-804. Epub 2008 Oct 10.. |
Molecular mechanisms regulating ocular apoptosis in zebrafish gdf6a mutants
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Citation:
Invest Ophthalmol Vis Sci. 2013 Jul 11. doi:pii: iovs.12-11315v1. 10.1167/iovs.12-11315. [Epub ahead of print] Epub:
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PURPOSE: To characterize the molecular mechanisms underlying retinal apoptosis induced by loss of Gdf6, a TGFβ ligand. METHODS... Organism or Cell Type:
zebrafish Citation Extract: Pant SD, March LD, Famulski JK, French CR, Lehmann OJ, Waskiewicz AJ. Molecular mechanisms regulating ocular apoptosis in zebrafish gdf6a mutants. Invest Ophthalmol Vis Sci. 2013 Jul 11. doi:pii: iovs.12-11315v1. 10.1167/iovs.12-11315. [Epub ahead of print]. |
Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death
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Citation:
Antivir Ther. 2009;14(7):899-909 Epub:
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BACKGROUND: Porcine reproductive and respiratory syndrome (PRRS) causes extensive economic losses in the swine industry.... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: porcine pulmonary alveolar macrophages Citation Extract: Patel D, Stein DA, Zhang YJ. Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death. Antivir Ther. 2009;14(7):899-909. |
Morpholino-Mediated Increase in Soluble Flt-1 Expression Results in Decreased Ocular and Tumor Neovascularization
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Citation:
PLoS ONE. 2012;7(3):e33576. doi:10.1371/journal.pone.0033576 Epub:
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Background Angiogenesis is a key process in several ocular disorders and cancers. Soluble Flt-1 is an alternatively spliced... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice, nude Citation Extract: Owen LA, Uehara H, Cahoon J, Huang W, Simonis J, Ambati BK. Morpholino-Mediated Increase in Soluble Flt-1 Expression Results in Decreased Ocular and Tumor Neovascularization. PLoS ONE. 2012;7(3):e33576. doi:10.1371/journal.pone.0033576. |
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination
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Citation:
Nat Genet. 2003 Aug;34(4):413-20 Epub:
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Nephronophthisis (NPHP), an autosomal recessive cystic kidney disease, leads to chronic renal failure in children. The genes... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Otto EA, Schermer B, Obara T, O'Toole JF, Hiller KS, Mueller AM, Ruf RG, Hoefele J, Beekmann F, Landau D, Foreman JW, Goodship JA, Strachan T, Kispert A, Wolf MT, Gagnadoux MF, Nivet H, Antignac C, Walz G, Drummond IA, Benzing T, Hildebrandt F. Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination. Nat Genet. 2003 Aug;34(4):413-20. |
Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development
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Citation:
Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10202-7. Epub 2011 Jun 1 Epub:
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What makes embryogenesis a robust and canalized process is an important question in developmental biology. A bone morphogenetic... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Paulsen M, Legewie S, Eils R, Karaulanov E, Niehrs C. Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10202-7. Epub 2011 Jun 1. |
Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish
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Development. 2011;138:4499-509; doi:10.1242/dev.067454 Epub:
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The extracellular matrix is crucial for organogenesis. It is a complex and dynamic component that regulates cell behavior by... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Patra C, Diehl F, Ferrazzi F, van Amerongen MJ, Novoyatleva T, Schaefer L, Mühlfeld C, Jungblut J, Engel FB. Nephronectin regulates atrioventricular canal differentiation via Bmp4-Has2 signaling in zebrafish. Development. 2011;138:4499-509; doi:10.1242/dev.067454. |
Neural crest specification by noncanonical Wnt signaling and PAR-1
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Citation:
Development. 2011;138:5441-50. doi:10.1242/dev.067280 Epub:
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Neural crest (NC) cells are multipotent progenitors that form at the neural plate border, undergo epithelial-mesenchymal... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Ossipova O, Sokol SY. Neural crest specification by noncanonical Wnt signaling and PAR-1. Development. 2011;138:5441-50. doi:10.1242/dev.067280 . |