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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting

Authors:
Oubaha M, Lin MI, Margaron Y, Filion D, Price EN, Zon LI, Côté JF, Gratton JP
Citation:
Blood. 2012 Aug 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Angiogenic sprouting requires that cell-cell contacts be maintained during migration of endothelial cells. Angiopoietin-1 (Ang-...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oubaha M, Lin MI, Margaron Y, Filion D, Price EN, Zon LI, Côté JF, Gratton JP. Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting. Blood. 2012 Aug 30. [Epub ahead of print].

Formation of the Ascidian Epidermal Sensory Neurons: Insights into the Origin of the Chordate Peripheral Nervous System

Authors:
Pasini A, Amiel A, Rothbacher U, Roure A, Lemaire P, Darras S
Citation:
PLoS Biol. 2006 Jun 27;4(7):e225 [Epub ahead of print]
Epub:
Not Epub
Abstract:
The vertebrate peripheral nervous system (PNS) originates from neural crest and placodes. While its developmental origin is the...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Pasini A, Amiel A, Rothbacher U, Roure A, Lemaire P, Darras S. Formation of the Ascidian Epidermal Sensory Neurons: Insights into the Origin of the Chordate Peripheral Nervous System. PLoS Biol. 2006 Jun 27;4(7):e225 [Epub ahead of print].

Function and regulation of zebrafish nkx2.2a during development of pancreatic islet and ducts

Authors:
Pauls S, Zecchin E, Tiso N, Bortolussi M, Argenton F
Citation:
Dev Biol. 2007 Apr 15;304(2):875-90. Epub 2007 Jan 20.
Epub:
Not Epub
Abstract:
In the mouse Nkx2.2 is expressed in the entire pancreatic anlage. Nevertheless, absence of Nkx2.2 only perturbs the development...
Organism or Cell Type:
zebrafish
Citation Extract:
Pauls S, Zecchin E, Tiso N, Bortolussi M, Argenton F. Function and regulation of zebrafish nkx2.2a during development of pancreatic islet and ducts. Dev Biol. 2007 Apr 15;304(2):875-90. Epub 2007 Jan 20..

Functional Analysis of Retinitis Pigmentosa 2 (RP2) Protein Reveals Variable Pathogenic Potential of Disease-Associated Missense Variants

Authors:
Patil SB, Hurd TW, Ghosh AK, Murga-Zamalloa CA, Khanna H
Citation:
PLoS ONE. 2011;6(6): e21379. doi:10.1371/journal.pone.0021379
Epub:
Not Epub
Abstract:
Genetic mutations are frequently associated with diverse phenotypic consequences, which limits the interpretation of the...
Organism or Cell Type:
zebrafish
Citation Extract:
Patil SB, Hurd TW, Ghosh AK, Murga-Zamalloa CA, Khanna H. Functional Analysis of Retinitis Pigmentosa 2 (RP2) Protein Reveals Variable Pathogenic Potential of Disease-Associated Missense Variants. PLoS ONE. 2011;6(6): e21379. doi:10.1371/journal.pone.0021379.

Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes

Authors:
Pearl EJ, Jarikji Z, Horb ME
Citation:
Dev Biol. 2011 Mar 1;351(1):135-45. Epub 2011 Jan 4
Epub:
Not Epub
Abstract:
Mutations in rfx6 were recently associated with Mitchell-Riley syndrome, which involves neonatal diabetes, and other digestive...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pearl EJ, Jarikji Z, Horb ME. Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes. Dev Biol. 2011 Mar 1;351(1):135-45. Epub 2011 Jan 4.

Functional conservation of erythropoietin signaling in zebrafish

Authors:
Paffett-Lugassy N, Hsia N, Fraenkel PG, Paw B, Leschinsky I, Barut B, Bahary N, Caro J, Handin R, Zon LI
Citation:
Blood. 2007 Oct 1;110(7):2718-26. Epub 2007 Jun 19
Epub:
Not Epub
Abstract:
Erythropoietin (Epo) and its cognate receptor (EpoR) are required for maintaining adequate levels of circulating erythrocytes...
Organism or Cell Type:
zebrafish
Citation Extract:
Paffett-Lugassy N, Hsia N, Fraenkel PG, Paw B, Leschinsky I, Barut B, Bahary N, Caro J, Handin R, Zon LI. Functional conservation of erythropoietin signaling in zebrafish. Blood. 2007 Oct 1;110(7):2718-26. Epub 2007 Jun 19.

Functional Knowledge Transfer for High-accuracy Prediction of Under-studied Biological Processes

Authors:
Park CY, Wong AK, Greene CS, Rowland J, Guan Y, Bongo LA, Burdine RD, Troyanskaya OG
Citation:
PLoS Comput Biol. 2013;9(3):e1002957. doi:10.1371/journal.pcbi.1002957
Epub:
Not Epub
Abstract:
A key challenge in genetics is identifying the functional roles of genes in pathways. Numerous functional genomics techniques (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Park CY, Wong AK, Greene CS, Rowland J, Guan Y, Bongo LA, Burdine RD, Troyanskaya OG. Functional Knowledge Transfer for High-accuracy Prediction of Under-studied Biological Processes. PLoS Comput Biol. 2013;9(3):e1002957. doi:10.1371/journal.pcbi.1002957.

Genetic modeling of Li-Fraumeni syndrome in zebrafish

Authors:
Parant JM, George SA, Holden JA, Yost HJ
Citation:
Dis Model Mech. 2010 Jan-Feb;3(1-2):45-56
Epub:
Not Epub
Abstract:
Li-Fraumeni syndrome (LFS) is a highly penetrant, autosomal dominant, human familial cancer predisposition. Although a key role...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Parant JM, George SA, Holden JA, Yost HJ. Genetic modeling of Li-Fraumeni syndrome in zebrafish. Dis Model Mech. 2010 Jan-Feb;3(1-2):45-56.

Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function

Authors:
Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, et al
Citation:
PLoS Genet. 2012;8(3):e1002584. doi:10.1371/journal.pgen.1002584
Epub:
Not Epub
Abstract:
Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, et al. Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function. PLoS Genet. 2012;8(3):e1002584. doi:10.1371/journal.pgen.1002584.

Germ cells in the crustacean Parhyale hawaiensis depend on Vasa protein for their maintenance but not for their formation

Authors:
Ozhan-Kizil G, Havemann J, Gerberding M
Citation:
Dev Biol. 2009 Mar 1;327(1):230-9. Epub 2008 Nov 5
Epub:
Not Epub
Abstract:
Germ cells are a population of cells that do not differentiate to form somatic tissue but form the egg and sperm that ensure...
Organism or Cell Type:
Parhyale hawaiensis
Citation Extract:
Ozhan-Kizil G, Havemann J, Gerberding M. Germ cells in the crustacean Parhyale hawaiensis depend on Vasa protein for their maintenance but not for their formation. Dev Biol. 2009 Mar 1;327(1):230-9. Epub 2008 Nov 5.

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