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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

A hypoplastic retinal lamination in the purpurin knock down embryo in zebrafish

Authors:
Nagashima M, Saito J, Mawatari K, Mori Y, Matsukawa T, Koriyama Y, Kato S
Citation:
Adv Exp Med Biol. 2010;664:517-24
Epub:
Not Epub
Abstract:
Recently, we cloned a photoreceptor-specific purpurin cDNA from axotomized goldfish retina. In the present study, we...
Organism or Cell Type:
zebrafish
Citation Extract:
Nagashima M, Saito J, Mawatari K, Mori Y, Matsukawa T, Koriyama Y, Kato S. A hypoplastic retinal lamination in the purpurin knock down embryo in zebrafish. Adv Exp Med Biol. 2010;664:517-24.

A Model organism approach: Defining the role of Neph proteins as regulators of neuron and kidney morphogenesis

Authors:
Neumann-Haefelin E, Kramer-Zucker A, Slanchev K, Hartleben B, Noutsou F, Martin K, Wanner N, Ritter A, Gödel M, Pagel P, Fu X, Müller A, Baumeister R, Walz G, Huber TB
Citation:
Hum Mol Genet. 2010 Mar 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mutations of the immunoglobulin superfamily proteins nephrin and Neph1 lead to congenital nephrotic syndrome in humans or mice...
Organism or Cell Type:
zebrafish
Citation Extract:
Neumann-Haefelin E, Kramer-Zucker A, Slanchev K, Hartleben B, Noutsou F, Martin K, Wanner N, Ritter A, Gödel M, Pagel P, Fu X, Müller A, Baumeister R, Walz G, Huber TB. A Model organism approach: Defining the role of Neph proteins as regulators of neuron and kidney morphogenesis. Hum Mol Genet. 2010 Mar 16. [Epub ahead of print].

A Mutation in the Srrm4 Gene Causes Alternative Splicing Defects and Deafness in the Bronx Waltzer Mouse

Authors:
Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJH, Cornell RA, Fritzsch B, Bánfi B
Citation:
PLoS Genet. 2012;8(10):e1002966. doi:10.1371/journal.pgen.1002966
Epub:
Not Epub
Abstract:
Sensory hair cells are essential for hearing and balance. Their development from epithelial precursors has been extensively...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJH, Cornell RA, Fritzsch B, Bánfi B. A Mutation in the Srrm4 Gene Causes Alternative Splicing Defects and Deafness in the Bronx Waltzer Mouse. PLoS Genet. 2012;8(10):e1002966. doi:10.1371/journal.pgen.1002966.

A Src-Tks5 Pathway Is Required for Neural Crest Cell Migration during Embryonic Development

Authors:
Murphy DA, Diaz B, Bromann PA, Tsai JH, Kawakami Y, Maurer J, Stewart RA, Izpisúa-Belmonte JC, Courtneidge SA
Citation:
PLoS ONE. 2011;6(7):e22499. doi:10.1371/journal.pone.0022499
Epub:
Not Epub
Abstract:
In the adult organism, cell migration is required for physiological processes such as angiogenesis and immune surveillance, as...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Murphy DA, Diaz B, Bromann PA, Tsai JH, Kawakami Y, Maurer J, Stewart RA, Izpisúa-Belmonte JC, Courtneidge SA. A Src-Tks5 Pathway Is Required for Neural Crest Cell Migration during Embryonic Development. PLoS ONE. 2011;6(7):e22499. doi:10.1371/journal.pone.0022499.

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

Authors:
Niethammer P, Grabher C, Look AT, Mitchison TJ
Citation:
Nature. 2009 Jun 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Barrier structures (for example, epithelia around tissues and plasma membranes around cells) are required for internal...
Organism or Cell Type:
zebrafish
Citation Extract:
Niethammer P, Grabher C, Look AT, Mitchison TJ. A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature. 2009 Jun 3. [Epub ahead of print].

Accumulation of RAF-1 kinase inhibitory protein (RKIP) is associated with CEP290-mediated photoreceptor degeneration in ciliopathies

Authors:
Murga-Zamalloa CA, Ghosh AK, Patil SB, Reed NA, Chan LS, Davuluri S, Peranen J, Hurd TW, Rachel RA, Khanna H
Citation:
J. Biol. Chem. 2011;[epub ahead of print] jbc.M111.237560. doi:10.1074/jbc.M111.237560
Epub:
Not Epub
Abstract:
Primary cilia regulate polarized protein trafficking in photoreceptors, which are dynamic and highly compartmentalized sensory...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Murga-Zamalloa CA, Ghosh AK, Patil SB, Reed NA, Chan LS, Davuluri S, Peranen J, Hurd TW, Rachel RA, Khanna H. Accumulation of RAF-1 kinase inhibitory protein (RKIP) is associated with CEP290-mediated photoreceptor degeneration in ciliopathies. J. Biol. Chem. 2011;[epub ahead of print] jbc.M111.237560. doi:10.1074/jbc.M111.237560.

Adenomatous polyposis coli control of retinoic acid biosynthesis is critical for zebrafish intestinal development and differentiation

Authors:
Nadauld LD, Sandoval IT, Chidester S, Yost HJ, Jones DA
Citation:
J Biol Chem. 2004 Dec 3;279(49):51581-9. Epub 2004 Sep 8.
Epub:
Not Epub
Abstract:
Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene cause uncontrolled proliferation and impaired...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nadauld LD, Sandoval IT, Chidester S, Yost HJ, Jones DA. Adenomatous polyposis coli control of retinoic acid biosynthesis is critical for zebrafish intestinal development and differentiation. J Biol Chem. 2004 Dec 3;279(49):51581-9. Epub 2004 Sep 8..

Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in Alzheimer's disease pathogenesis

Authors:
Newman M, Tucker B, Nornes S, Ward A, Lardelli M
Citation:
J Alzheimers Dis. 2009 Jan;16(1):133-47
Epub:
Not Epub
Abstract:
Aberrant splicing and point mutations in the human presenilin genes, PSEN1 and PSEN2, have been linked to familial forms of...
Organism or Cell Type:
zebrafish
Citation Extract:
Newman M, Tucker B, Nornes S, Ward A, Lardelli M. Altering presenilin gene activity in zebrafish embryos causes changes in expression of genes with potential involvement in Alzheimer's disease pathogenesis. J Alzheimers Dis. 2009 Jan;16(1):133-47.

Antisense Morpholino-Oligomers Directed against the 5' End of the Genome Inhibit Coronavirus Proliferation and Growth

Authors:
Neuman BW, Stein DA, Kroeker AD, Paulino AD, Moulton HM, Iversen PL, Buchmeier MJ
Citation:
J Virol. 2004 Jun;78(11):5891-5899
Epub:
Not Epub
Abstract:
Conjugation of a peptide related to the human immunodeficiency virus type 1 Tat represents a novel method for delivery of...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: mouse astrocytoma DBT
Citation Extract:
Neuman BW, Stein DA, Kroeker AD, Paulino AD, Moulton HM, Iversen PL, Buchmeier MJ. Antisense Morpholino-Oligomers Directed against the 5' End of the Genome Inhibit Coronavirus Proliferation and Growth. J Virol. 2004 Jun;78(11):5891-5899.

Antisense Targeting of cFLIP Sensitizes Activated T Cells to Undergo Apoptosis and Desensitizes Responses to Contact Dermatitis

Authors:
Mourich DV, Jendrzejewski JL, Marshall NB, Hinrichs DJ, Iversen PL, Brand RM
Citation:
J Invest Dermatol. 2009 Feb 19. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Contact dermatitis is the result of inflammatory responses mediated by hapten-specific activated CD8+ and CD4+ T cells....
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice and cell culture: T cells
Citation Extract:
Mourich DV, Jendrzejewski JL, Marshall NB, Hinrichs DJ, Iversen PL, Brand RM. Antisense Targeting of cFLIP Sensitizes Activated T Cells to Undergo Apoptosis and Desensitizes Responses to Contact Dermatitis. J Invest Dermatol. 2009 Feb 19. [Epub ahead of print].

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