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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
Exon-skipping events in candidates for clinical trials of morpholino
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Citation:
Pediatr Int. 2011:53(4)524–9 Epub:
Not Epub Abstract:
Background: Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are caused by abnormalities in the DMD gene.... Organism or Cell Type:
cell culture: primary human fibroblasts Citation Extract: Nakano S, Ozasa S, Yoshioka K, Fujii I, Mitsui K, Nomura K, Kosuge H, Endo F, Matsukura M, Kimura S. Exon-skipping events in candidates for clinical trials of morpholino. Pediatr Int. 2011:53(4)524–9. |
Exon-skipping therapy for Duchenne muscular dystrophy
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Citation:
Neuropathology. 2009 May 22. [Epub ahead of print] Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a lethal muscle disorder caused by mutations in the DMD gene for which no mutation-... Organism or Cell Type:
mouse and dog Citation Extract: Nakamura A, Takeda S. Exon-skipping therapy for Duchenne muscular dystrophy. Neuropathology. 2009 May 22. [Epub ahead of print]. |
FGF signalling during embryo development regulates cilia length in diverse epithelia
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Citation:
Nature. 2009 Feb 25. [Epub ahead of print] Epub:
Not Epub Organism or Cell Type:
zebrafish Citation Extract: Neugebauer JM, Amack JD, Peterson AG, Bisgrove BW, Yost HJ. FGF signalling during embryo development regulates cilia length in diverse epithelia. Nature. 2009 Feb 25. [Epub ahead of print]. |
FGF-dependent mechanosensory organ patterning in zebrafish
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Citation:
Science. 2008 Jun 27;320(5884):1774-7 Epub:
Not Epub Abstract:
During development, organ primordia reorganize to form repeated functional units. In zebrafish (Danio rerio), mechanosensory... Organism or Cell Type:
zebrafish Citation Extract: Nechiporuk A, Raible DW. FGF-dependent mechanosensory organ patterning in zebrafish. Science. 2008 Jun 27;320(5884):1774-7. |
Focal Adhesion Kinase Promotes Integrin Adhesion Dynamics Necessary for Chemotropic Turning of Nerve Growth Cones
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Citation:
J Neurosci. 2011 Sept 21;31(38):13585-95. doi: 10.1523/JNEUROSCI.2381-11.2011 Epub:
Not Epub Abstract:
The ability of extending axons to navigate using combinations of extracellular cues is essential for proper neural network... Organism or Cell Type:
cell culture: Xenopus spinal neuron neurites Citation Extract: Myers JP, Gomez TM. Focal Adhesion Kinase Promotes Integrin Adhesion Dynamics Necessary for Chemotropic Turning of Nerve Growth Cones. J Neurosci. 2011 Sept 21;31(38):13585-95. doi: 10.1523/JNEUROSCI.2381-11.2011 . |
Forkhead transcription factor foxe1 regulates chondrogenesis in zebrafish
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Citation:
J Exp Zoolog B Mol Dev Evol. 2009 Jun 1. [Epub ahead of print] Epub:
Not Epub Abstract:
Forkhead transcription factor (Fox) e1 is a causative gene for Bamforth-Lazarus syndrome, which is characterized by... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Nakada C, Iida A, Tabata Y, Watanabe S. Forkhead transcription factor foxe1 regulates chondrogenesis in zebrafish. J Exp Zoolog B Mol Dev Evol. 2009 Jun 1. [Epub ahead of print]. |
Functional characterization and targeted correction of ATM mutations identified in Japanese patients with ataxia-telangiectasia
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Citation:
Hum Mutat. 2012 Jan;33(1):198-208. doi: 10.1002/humu.21632. Epub 2011 Nov 9. Epub:
Not Epub Abstract:
A recent challenge for investigators studying the progressive neurological disease ataxia-telangiectasia (A-T) is to identify... Delivery Method:
Some Vivo-Morpholino, some Endo-Porter Organism or Cell Type:
cell culture: lymphoblastoid cell line Citation Extract: Nakamura K, Du L, Tunuguntla R, Fike F, Cavalieri S, Morio T, Mizutani S, Brusco A, Gatti RA. Functional characterization and targeted correction of ATM mutations identified in Japanese patients with ataxia-telangiectasia. Hum Mutat. 2012 Jan;33(1):198-208. doi: 10.1002/humu.21632. Epub 2011 Nov 9.. |
Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm
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Citation:
Dis Model Mech. 2012 Dec 7. [Epub ahead of print] Epub:
Not Epub Abstract:
Atrial fibrillation (AF) is the most common cardiac arrhythmia and carries a significant risk of stroke and heart failure. The... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Müller II, Melville DB, Tanwar V, Rybski WM, Mukherjee A, Shoemaker BM, Wang WD, Schoenhard JA, Roden DM, Darbar D, Knapik EW, Hatzopoulos AK. Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm. Dis Model Mech. 2012 Dec 7. [Epub ahead of print]. |
Gain- and loss-of-function in chick embryos by electroporation.
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Citation:
Mech Dev. 2004 Sep;121(9):1137-43. Epub:
Not Epub Abstract:
It remained very difficult to manipulate gene expression in chick embryos until the advent of in ovo electroporation which... Delivery Method:
Electroporation Organism or Cell Type:
chick embryo Citation Extract: Nakamura H, Katahira T, Sato T, Watanabe Y, Funahashi J.. Gain- and loss-of-function in chick embryos by electroporation.. Mech Dev. 2004 Sep;121(9):1137-43.. |
Gene Knockdowns in Adult Animals: PPMOs and Vivo-Morpholinos
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Citation:
Molecules. 2009 Mar 25;14(3):1304-23 Epub:
Not Epub Abstract:
Antisense molecules do not readily cross cell membranes. This has limited the use of antisense to systems where techniques have... Citation Extract: Moulton JD, Jiang S. Gene Knockdowns in Adult Animals: PPMOs and Vivo-Morpholinos. Molecules. 2009 Mar 25;14(3):1304-23. |