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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
Morpholinos and Their Peptide Conjugates: Therapeutic Promise and Challenge for Duchenne Muscular Dystrophy
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Citation:
Biochim Biophys Acta. 2010;1798(12):2296-2303 Epub:
Not Epub Abstract:
Exon-skipping efficacy of phosphodiamidate morpholino oligomers (PMOs) or the conjugates of PMOs with cell-penetrating peptides... Delivery Method:
peptide-coupled versus bare oligo, injected Organism or Cell Type:
mouse, monkey, dog Citation Extract: Moulton HM, Moulton JD. Morpholinos and Their Peptide Conjugates: Therapeutic Promise and Challenge for Duchenne Muscular Dystrophy. Biochim Biophys Acta. 2010;1798(12):2296-2303 . |
Msx1 and Pax3 Cooperate to Mediate FGF8 and WNT Signals during Xenopus Neural Crest Induction
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Citation:
Dev Cell. 2005 Feb;8(2):167-78 Epub:
Not Epub Abstract:
FGF, WNT, and BMP signaling promote neural crest formation at the neural plate boundary in vertebrate embryos. To understand... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Monsoro-Burq AH, Wang E, Harland R. Msx1 and Pax3 Cooperate to Mediate FGF8 and WNT Signals during Xenopus Neural Crest Induction. Dev Cell. 2005 Feb;8(2):167-78. |
Mutation in utp15 Disrupts Vascular Patterning in a p53-Dependent Manner in Zebrafish Embryos
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Citation:
PLoS ONE. 2011;6(9): e25013. doi:10.1371/journal.pone.0025013 Epub:
Not Epub Abstract:
Background Angiogenesis is the process by which the highly branched and functional vasculature arises from the major vessels,... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Mouillesseaux K, Chen JN. Mutation in utp15 Disrupts Vascular Patterning in a p53-Dependent Manner in Zebrafish Embryos. PLoS ONE. 2011;6(9): e25013. doi:10.1371/journal.pone.0025013. |
Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia
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Citation:
Nat Genet. 2012 Mar 4. doi: 10.1038/ng.1106. [Epub ahead of print] Epub:
Not Epub Abstract:
Primary ciliary dyskinesia most often arises from loss of the dynein motors that power ciliary beating. Here we show that... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Mitchison HM, Schmidts M, Loges NT, Freshour J, Dritsoula A, Hirst RA, O'Callaghan C, Blau H, Al Dabbagh M, Olbrich H, Beales PL, Yagi T, Mussaffi H, Chung EM, Omran H, Mitchell DR. Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia. Nat Genet. 2012 Mar 4. doi: 10.1038/ng.1106. [Epub ahead of print]. |
Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis
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Citation:
Development. 2010 Apr;137(8):1315-25 Epub:
Not Epub Abstract:
Neural tube formation is one of the most dynamic morphogenetic processes of vertebrate development. However, the molecules... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Morita H, Nandadasa S, Yamamoto TS, Terasaka-Iioka C, Wylie C, Ueno N. Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis. Development. 2010 Apr;137(8):1315-25. |
Neucrin, a novel secreted antagonist of canonical Wnt signaling, plays roles in developing neural tissues in zebrafish
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Citation:
Mech Dev. 2012 Jan 12. [Epub ahead of print] Epub:
Not Epub Abstract:
Wnt signaling plays crucial roles in neural development. We previously identified Neucrin, a neural-specific secreted... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Miyake A, Nihno S, Murakoshi Y, Satsuka A, Nakayama Y, Itoh N. Neucrin, a novel secreted antagonist of canonical Wnt signaling, plays roles in developing neural tissues in zebrafish. Mech Dev. 2012 Jan 12. [Epub ahead of print]. |
Neuron and Sensory Epithelial Cell Fate Is Sequentially Determined by Notch Signaling in Zebrafish Lateral Line Development
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Citation:
J Neurosci. 2011;31(43):15522-30 doi:10.1523/JNEUROSCI.3948-11.2011 Epub:
Not Epub Abstract:
Sensory systems are specialized to recognize environmental changes. Sensory organs are complex structures composed of different... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Mizoguchi T, Togawa S, Kawakami K, Itoh M. Neuron and Sensory Epithelial Cell Fate Is Sequentially Determined by Notch Signaling in Zebrafish Lateral Line Development. J Neurosci. 2011;31(43):15522-30 doi:10.1523/JNEUROSCI.3948-11.2011 . |
Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal Development
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Citation:
Science. 2013;341(6149):1002-5. doi:10.1126/science.1240376 Epub:
Not Epub Abstract:
Eggs and oocytes have a remarkable ability to induce transcription of sperm after normal fertilization and in somatic nuclei... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Miyamoto K, Teperek M, Yusa K, Allen GE, Bradshaw CR, Gurdon JB. Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal Development. Science. 2013;341(6149):1002-5. doi:10.1126/science.1240376. |
Peptide-assisted delivery of steric-blocking antisense oligomers
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Citation:
Curr Opin Mol Ther. 2003 Apr;5(2):123-32 Epub:
Not Epub Abstract:
Cationic transport peptides conjugated to steric blocking antisense oligomers (oligos) increase oligo uptake in eukaryotic cell... Delivery Method:
not applicable Organism or Cell Type:
not applicable Citation Extract: Moulton HM, Moulton JD. Peptide-assisted delivery of steric-blocking antisense oligomers. Curr Opin Mol Ther. 2003 Apr;5(2):123-32. |
Personalised Genetic Intervention for Duchenne Muscular Dystrophy: Antisense Oligomers and Exon Skipping
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Citation:
Curr Mol Pharmacol. 2009 Jan;2(1):110-121 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) arises from protein-truncating mutations in the large dystrophin gene that preclude synthesis... Citation Extract: Mitrpant C, Fletcher S, Wilton SD. Personalised Genetic Intervention for Duchenne Muscular Dystrophy: Antisense Oligomers and Exon Skipping. Curr Mol Pharmacol. 2009 Jan;2(1):110-121. |