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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Enhanced exon skipping in the 4CV dystrophic mouse model of muscular dystrophy through refined oligomer design

Authors:
Mitrpant C, Fletcher S, Pinniger G, Johnsen R, Kole R, Wilton SD
Citation:
Neuromusc Disord. 2012;22(9):858
Epub:
Not Epub
Abstract:
Antisense oligomer (AO) induced dual dystrophin exon skipping was studied in the B6Ros.Cg-Dmdmdx-4Cv/J (4CV) mouse, an...
Delivery Method:
Injection
Organism or Cell Type:
Mouse, mdx-4Cv
Citation Extract:
Mitrpant C, Fletcher S, Pinniger G, Johnsen R, Kole R, Wilton SD. Enhanced exon skipping in the 4CV dystrophic mouse model of muscular dystrophy through refined oligomer design. Neuromusc Disord. 2012;22(9):858.

Fgf22 regulated by Fgf3/Fgf8 signaling is required for zebrafish midbrain development

Authors:
Miyake A, Itoh N
Citation:
Biol Open. 2013 Apr 10;2(5):515-24. doi: 10.1242/bio.20134226. Print 2013 May 15.
Epub:
Not Epub
Abstract:
Fibroblast growth factor (Fgf) signaling plays important roles in various developmental processes including brain development....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miyake A, Itoh N. Fgf22 regulated by Fgf3/Fgf8 signaling is required for zebrafish midbrain development. Biol Open. 2013 Apr 10;2(5):515-24. doi: 10.1242/bio.20134226. Print 2013 May 15..

Flamingo, a cadherin-type receptor involved in the Drosophila planar polarity pathway, can block signaling via the canonical wnt pathway in Xenopus laevis

Authors:
Morgan R, El-Kadi AM, Theokli C
Citation:
Int J Dev Biol. 2003 May;47(4):245-52
Epub:
Not Epub
Abstract:
The Flamingo gene encodes a seven-pass transmembrane receptor of the cadherin super family and is one of a growing number of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Morgan R, El-Kadi AM, Theokli C. Flamingo, a cadherin-type receptor involved in the Drosophila planar polarity pathway, can block signaling via the canonical wnt pathway in Xenopus laevis. Int J Dev Biol. 2003 May;47(4):245-52.

FLASH, a component of the FAS-CAPSASE8 apoptotic pathway, is directly regulated by Hoxb4 in the notochord

Authors:
Morgan R, Nalliah A, Morsi El-Kadi AS
Citation:
Dev Biol. 2004 Jan 1;265(1):105-12
Epub:
Not Epub
Abstract:
The Hox genes are a family of homeodomain-containing transcription factors that confer positional identity during development....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus notochords
Citation Extract:
Morgan R, Nalliah A, Morsi El-Kadi AS. FLASH, a component of the FAS-CAPSASE8 apoptotic pathway, is directly regulated by Hoxb4 in the notochord. Dev Biol. 2004 Jan 1;265(1):105-12.

Function of Pax1 and Pax9 in the sclerotome of medaka fish

Authors:
Mise T, Iijima M, Inohaya K, Kudo A, Wada H
Citation:
Genesis. 2008 Apr 7;46(4):185-192 [Epub ahead of print]
Epub:
Not Epub
Abstract:
We examined the expression and functions of Pax1 and Pax9 in a teleost fish, the medaka Oryzias latipes. While Pax1 and Pax9...
Organism or Cell Type:
medaka embryos
Citation Extract:
Mise T, Iijima M, Inohaya K, Kudo A, Wada H. Function of Pax1 and Pax9 in the sclerotome of medaka fish. Genesis. 2008 Apr 7;46(4):185-192 [Epub ahead of print] .

Gene switching: analyzing a broad range of mutations using steric block antisense oligonucleotides

Authors:
Morcos PA
Citation:
Methods Enzymol 2000;313:174-89
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Scrape Delivery
Organism or Cell Type:
Cell Culture: human HeLa pLuc 705 cell and HeLa pRLCMV
Citation Extract:
Morcos PA. Gene switching: analyzing a broad range of mutations using steric block antisense oligonucleotides. Methods Enzymol 2000;313:174-89.

Generation of FGF reporter transgenic zebrafish and their utility in chemical screens

Authors:
Molina GA, Watkins SC, Tsang M
Citation:
BMC Dev Biol. 2007 Jun 6;7:62
Epub:
Not Epub
Abstract:
BACKGROUND: Fibroblast Growth Factors (FGFs) represent a large family of secreted proteins that are required for proper...
Organism or Cell Type:
zebrafish
Citation Extract:
Molina GA, Watkins SC, Tsang M. Generation of FGF reporter transgenic zebrafish and their utility in chemical screens. BMC Dev Biol. 2007 Jun 6;7:62.

Genes required for functional glycosylation of dystroglycan are conserved in zebrafish

Authors:
Moore CJ, Goh HT, Hewitt JE
Citation:
Genomics. 2008 Sep;92(3):159-67. Epub 2008 Jul 15.
Epub:
Not Epub
Abstract:
Mutations in human genes encoding proteins involved in alpha-dystroglycan glycosylation result in dystroglycanopathies: severe...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moore CJ, Goh HT, Hewitt JE. Genes required for functional glycosylation of dystroglycan are conserved in zebrafish. Genomics. 2008 Sep;92(3):159-67. Epub 2008 Jul 15..

Heartbeat regulates cardiogenesis by suppressing retinoic acid signaling via expression of miR-143

Authors:
Miyasaka KY, Kida YS, Banjo T, Ueki Y, Nagayama K, Matsumoto T, Sato M, Ogura T
Citation:
Mech Dev. 2011 Jan-Feb;128(1-2):18-28. Epub 2010 Sep 30
Epub:
Not Epub
Abstract:
Cardiogenesis proceeds with concomitant changes in hemodynamics to accommodate the circulatory demands of developing organs and...
Organism or Cell Type:
zebrafish
Citation Extract:
Miyasaka KY, Kida YS, Banjo T, Ueki Y, Nagayama K, Matsumoto T, Sato M, Ogura T. Heartbeat regulates cardiogenesis by suppressing retinoic acid signaling via expression of miR-143. Mech Dev. 2011 Jan-Feb;128(1-2):18-28. Epub 2010 Sep 30.

HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers

Authors:
Moulton HM, Hase MC, Smith KM, Iversen PL
Citation:
Antisense Nucleic Acid Drug Dev. 2003 Feb;13(1):31-43
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligomers (PMO) are uncharged antisense molecules that bind complementary sequences of RNA,...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: various Hela
Citation Extract:
Moulton HM, Hase MC, Smith KM, Iversen PL. HIV Tat peptide enhances cellular delivery of antisense morpholino oligomers. Antisense Nucleic Acid Drug Dev. 2003 Feb;13(1):31-43.

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