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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

A crucial role of a high mobility group protein HMGA2 in cardiogenesis

Authors:
Monzen K, Ito Y, Naito AT, Kasai H, Hiroi Y, Hayashi D, Shiojima I, Yamazaki T, Miyazono K, Asashima M, Nagai R, Komuro I
Citation:
Nat Cell Biol. 2008 May;10(5):567-74. Epub 2008 Apr 20.
Epub:
Not Epub
Abstract:
The high mobility group (HMG) of nuclear proteins regulates expression of many genes through architectural remodelling of the...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Monzen K, Ito Y, Naito AT, Kasai H, Hiroi Y, Hayashi D, Shiojima I, Yamazaki T, Miyazono K, Asashima M, Nagai R, Komuro I. A crucial role of a high mobility group protein HMGA2 in cardiogenesis. Nat Cell Biol. 2008 May;10(5):567-74. Epub 2008 Apr 20..

A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs)

Authors:
Motta-Mena LB, Smith SA, Mallory MJ, Jackson J, Wang J, Lynch KW
Citation:
J Biol Chem. 2011 Jun 3;286(22):20043-53. Epub 2011 Apr 20
Epub:
Not Epub
Abstract:
Alternative splicing is typically controlled by complexes of regulatory proteins that bind to sequences within or flanking...
Delivery Method:
Electroporation
Organism or Cell Type:
cell culture: human JSL1 T-cell line
Citation Extract:
Motta-Mena LB, Smith SA, Mallory MJ, Jackson J, Wang J, Lynch KW. A disease-associated polymorphism alters splicing of the human CD45 phosphatase gene by disrupting combinatorial repression by heterogeneous nuclear ribonucleoproteins (hnRNPs). J Biol Chem. 2011 Jun 3;286(22):20043-53. Epub 2011 Apr 20.

A G protein-coupled receptor is essential for Schwann cells to initiate myelination

Authors:
Monk KR, Naylor SG, Glenn TD, Mercurio S, Perlin JR, Dominguez C, Moens CB, Talbot WS
Citation:
Science. 2009 Sep 11;325(5946):1402-5
Epub:
Not Epub
Abstract:
The myelin sheath allows axons to conduct action potentials rapidly in the vertebrate nervous system. Axonal signals activate...
Organism or Cell Type:
zebrafish
Citation Extract:
Monk KR, Naylor SG, Glenn TD, Mercurio S, Perlin JR, Dominguez C, Moens CB, Talbot WS. A G protein-coupled receptor is essential for Schwann cells to initiate myelination. Science. 2009 Sep 11;325(5946):1402-5.

A gene regulatory network directed by zebrafish No tail accounts for its roles in mesoderm formation

Authors:
Morley RH, Lachani K, Keefe D, Gilchrist MJ, Flicek P, Smith JC, Wardle FC
Citation:
Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3829-34. Epub 2009 Feb 18
Epub:
Not Epub
Abstract:
Using chromatin immunoprecipitation combined with genomic microarrays we have identified targets of No tail (Ntl), a zebrafish...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morley RH, Lachani K, Keefe D, Gilchrist MJ, Flicek P, Smith JC, Wardle FC. A gene regulatory network directed by zebrafish No tail accounts for its roles in mesoderm formation. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3829-34. Epub 2009 Feb 18.

A guide to analysis of cardiac phenotypes in the zebrafish embryo

Authors:
Miura GI, Yelon D
Citation:
Methods Cell Biol. 2011;101:161-80
Epub:
Not Epub
Abstract:
The zebrafish is an ideal model organism for investigating the molecular mechanisms underlying cardiogenesis, due to the...
Organism or Cell Type:
zebrafish
Citation Extract:
Miura GI, Yelon D. A guide to analysis of cardiac phenotypes in the zebrafish embryo. Methods Cell Biol. 2011;101:161-80.

A maternally localised Wnt ligand required for axial patterning in the cnidarian Clytia hemisphaerica

Authors:
Momose T, Derelle R, Houliston E
Citation:
Development. 2008 Jun;135(12):2105-13. Epub 2008 May 14.
Epub:
Not Epub
Abstract:
Regionalised activation of canonical Wnt signalling via beta-catenin stabilisation is a key early step in embryonic patterning...
Organism or Cell Type:
Clytia hemisphaerica
Citation Extract:
Momose T, Derelle R, Houliston E. A maternally localised Wnt ligand required for axial patterning in the cnidarian Clytia hemisphaerica. Development. 2008 Jun;135(12):2105-13. Epub 2008 May 14..

A novel functional role of iduronate-2-sulfatase in zebrafish early development

Authors:
Moro E, Tomanin R, Friso A, Modena N, Tiso N, Scarpa M, Argenton F
Citation:
Matrix Biol. 2009 Sep 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Sulfated glycosaminoglycan chains of extracellular matrix and cell membrane-tethered proteoglycans exert specific cellular...
Organism or Cell Type:
zebrafish
Citation Extract:
Moro E, Tomanin R, Friso A, Modena N, Tiso N, Scarpa M, Argenton F. A novel functional role of iduronate-2-sulfatase in zebrafish early development. Matrix Biol. 2009 Sep 14. [Epub ahead of print].

A role for the Myoblast city homologues Dock1 and Dock5 and the adaptor proteins Crk and Crk-like in zebrafish myoblast fusion

Authors:
Moore CA, Parkin CA, Bidet Y, Ingham PW
Citation:
Development. 2007 Sep;134(17):3145-53. Epub 2007 Aug 1.
Epub:
Not Epub
Abstract:
Myoblast fusion follows a defined sequence of events that is strikingly similar in vertebrates and invertebrates. Genetic...
Organism or Cell Type:
zebrafish
Citation Extract:
Moore CA, Parkin CA, Bidet Y, Ingham PW. A role for the Myoblast city homologues Dock1 and Dock5 and the adaptor proteins Crk and Crk-like in zebrafish myoblast fusion. Development. 2007 Sep;134(17):3145-53. Epub 2007 Aug 1..

A Zebrafish Model of Roberts Syndrome Reveals That Esco2 Depletion Interferes with Development by Disrupting the Cell Cycle

Authors:
Mönnich M, Kuriger Z, Print CG, Horsfield JA
Citation:
PLoS ONE. 2011;6(5):e20051. doi:10.1371/journal.pone.0020051
Epub:
Not Epub
Abstract:
The human developmental diseases Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS) are both caused by mutations in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mönnich M, Kuriger Z, Print CG, Horsfield JA. A Zebrafish Model of Roberts Syndrome Reveals That Esco2 Depletion Interferes with Development by Disrupting the Cell Cycle. PLoS ONE. 2011;6(5):e20051. doi:10.1371/journal.pone.0020051.

Achieving efficient delivery of morpholino oligos in cultured cells

Authors:
Morcos PA
Citation:
Genesis. 2001 Jul;30(3):94-102
Epub:
Not Epub
Abstract:
One of the many features that make morpholino oligos unique among the antisense structural types is an uncharged backbone....
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: HeLa AntisenseTest System
Citation Extract:
Morcos PA. Achieving efficient delivery of morpholino oligos in cultured cells. Genesis. 2001 Jul;30(3):94-102.

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