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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Tissue-Restricted Expression of Nrf2 and Its Target Genes in Zebrafish with Gene-Specific Variations in the Induction Profiles

Authors:
Nakajima H, Nakajima-Takagi Y, Tsujita T, Akiyama S-I, Wakasa T, Mukaigasa K, Kaneko H, Tamaru Y, Yamamoto M, Kobayashi M
Citation:
PLoS ONE. 2011;6(10):e26884. doi:10.1371/journal.pone.0026884
Epub:
Not Epub
Abstract:
The Keap1-Nrf2 system serves as a defense mechanism against oxidative stress and electrophilic toxicants by inducing more than...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nakajima H, Nakajima-Takagi Y, Tsujita T, Akiyama S-I, Wakasa T, Mukaigasa K, Kaneko H, Tamaru Y, Yamamoto M, Kobayashi M. Tissue-Restricted Expression of Nrf2 and Its Target Genes in Zebrafish with Gene-Specific Variations in the Induction Profiles. PLoS ONE. 2011;6(10):e26884. doi:10.1371/journal.pone.0026884.

Topoisomerase IIβ is required for lamina-specific targeting of retinal ganglion cell axons and dendrites

Authors:
Nevin LM, Xiao T, Staub W, Baier H
Citation:
Development. 2011 June 15;138,2457-2465. doi: 10.1242/dev.060335
Epub:
Not Epub
Abstract:
The specific partnering of synaptically connected neurons is central to nervous system function. Proper wiring requires the...
Organism or Cell Type:
zebrafish
Citation Extract:
Nevin LM, Xiao T, Staub W, Baier H. Topoisomerase IIβ is required for lamina-specific targeting of retinal ganglion cell axons and dendrites. Development. 2011 June 15;138,2457-2465. doi: 10.1242/dev.060335.

Transcriptional Repressor foxl1 Regulates Central Nervous System Development by Suppressing shh Expression in Zebra Fish

Authors:
Nakada C, Satoh S, Tabata Y, Arai K, Watanabe S
Citation:
Mol Cell Biol. 2006 Oct;26(19):7246-57
Epub:
Not Epub
Abstract:
We identified zebra fish forkhead transcription factor l1 (zfoxl1) as a gene strongly expressed in neural tissues such as...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nakada C, Satoh S, Tabata Y, Arai K, Watanabe S. Transcriptional Repressor foxl1 Regulates Central Nervous System Development by Suppressing shh Expression in Zebra Fish. Mol Cell Biol. 2006 Oct;26(19):7246-57.

Tumor Necrosis Factor-Alpha Is Produced by Dying Retinal Neurons and Is Required for Müller Glia Proliferation during Zebrafish Retinal Regeneration

Authors:
Nelson CM, Ackerman KM, O'Hayer P, Bailey TJ, Gorsuch RA, Hyde DR
Citation:
J Neurosci. 2013;33(15):6524-6539. doi:10.1523/JNEUROSCI.3838-12.2013
Epub:
Not Epub
Abstract:
Intense light exposure causes photoreceptor apoptosis in dark-adapted adult albino zebrafish (Danio rerio). Subsequently,...
Organism or Cell Type:
zebrafish
Citation Extract:
Nelson CM, Ackerman KM, O'Hayer P, Bailey TJ, Gorsuch RA, Hyde DR. Tumor Necrosis Factor-Alpha Is Produced by Dying Retinal Neurons and Is Required for Müller Glia Proliferation during Zebrafish Retinal Regeneration. J Neurosci. 2013;33(15):6524-6539. doi:10.1523/JNEUROSCI.3838-12.2013 .

Ubiad1 Is an Antioxidant Enzyme that Regulates eNOS Activity by CoQ10 Synthesis

Authors:
Mugoni V, Postel R, Catanzaro V, De Luca E, Turco E, Digilio G, Silengo L, Murphy MP, Medana C, Stainier DY, Bakkers J, Santoro MM
Citation:
Cell. 2013 Jan 31;152(3):504-18. doi: 10.1016/j.cell.2013.01.013
Epub:
Not Epub
Abstract:
Protection against oxidative damage caused by excessive reactive oxygen species (ROS) by an antioxidant network is essential...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mugoni V, Postel R, Catanzaro V, De Luca E, Turco E, Digilio G, Silengo L, Murphy MP, Medana C, Stainier DY, Bakkers J, Santoro MM. Ubiad1 Is an Antioxidant Enzyme that Regulates eNOS Activity by CoQ10 Synthesis. Cell. 2013 Jan 31;152(3):504-18. doi: 10.1016/j.cell.2013.01.013.

Ucmaa (Grp-2) is required for zebrafish skeletal development. Evidence for a functional role of its glutamate γ-carboxylation

Authors:
Neacsu CD, Grosch M, Tejada M, Winterpacht A, Paulsson M, Wagener R, Tagariello A
Citation:
Matrix Biol. 2011 Aug 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
UCMA (alternatively named GRP) is a novel member of the family of γ-carboxyglutamate (Gla) containing proteins that is mainly...
Organism or Cell Type:
zebrafish
Citation Extract:
Neacsu CD, Grosch M, Tejada M, Winterpacht A, Paulsson M, Wagener R, Tagariello A. Ucmaa (Grp-2) is required for zebrafish skeletal development. Evidence for a functional role of its glutamate γ-carboxylation. Matrix Biol. 2011 Aug 1. [Epub ahead of print].

Unique, Highly Proliferative Growth Phenotype Expressed by Embryonic and Neointimal Smooth Muscle Cells Is Driven by Constitutive Akt, mTOR, and p70S6K Signaling and Is Actively Repressed by PTEN

Authors:
Mourani PM, Garl PJ, Wenzlau JM, Carpenter TC, Stenmark KR, Weiser-Evans MC
Citation:
Circulation. 2004 Mar 16;109(10):1299-306. Epub 2004 Mar 01.
Epub:
Not Epub
Abstract:
BACKGROUND: At distinct times during embryonic development and after vascular injury, smooth muscle cells (SMCs) exhibit a...
Delivery Method:
Osmotic Delivery System
Organism or Cell Type:
Sprague-Dawley rats smooth muscle cell
Citation Extract:
Mourani PM, Garl PJ, Wenzlau JM, Carpenter TC, Stenmark KR, Weiser-Evans MC. Unique, Highly Proliferative Growth Phenotype Expressed by Embryonic and Neointimal Smooth Muscle Cells Is Driven by Constitutive Akt, mTOR, and p70S6K Signaling and Is Actively Repressed by PTEN. Circulation. 2004 Mar 16;109(10):1299-306. Epub 2004 Mar 01..

Using morpholinos to control gene expression

Authors:
Moulton JD
Citation:
Curr Protoc Nucleic Acid Chem. 2007 Jan;Chapter 4:Unit 4.30
Epub:
Not Epub
Abstract:
Morpholino oligonucleotides are stable, uncharged, water-soluble molecules used to block complementary sequences of RNA,...
Citation Extract:
Moulton JD. Using morpholinos to control gene expression. Curr Protoc Nucleic Acid Chem. 2007 Jan;Chapter 4:Unit 4.30.

Using morpholinos to control gene expression

Authors:
Moulton JD, Yan YL
Citation:
Curr Protoc Mol Biol. 2008 Jul;Chapter 26:Unit26.8
Epub:
Not Epub
Abstract:
Morpholino oligonucleotides are stable, uncharged, water-soluble molecules that bind to complementary sequences of RNA, thereby...
Citation Extract:
Moulton JD, Yan YL. Using morpholinos to control gene expression. Curr Protoc Mol Biol. 2008 Jul;Chapter 26:Unit26.8.

WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis

Authors:
Murugan S, Shan J, Kühl SJ, Tata A, Pietilä I, Kühl M, Vainio SJ
Citation:
Exp Cell Res. 2012;[Epub ahead of print] 10.1016/j.yexcr.2012.03.008
Epub:
Not Epub
Abstract:
Wnt4, a member of the Wnt superfamily of signaling molecules, is critical for mammalian kidney development, since nephrogenesis...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Murugan S, Shan J, Kühl SJ, Tata A, Pietilä I, Kühl M, Vainio SJ. WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis. Exp Cell Res. 2012;[Epub ahead of print] 10.1016/j.yexcr.2012.03.008.

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