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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Amyloid-β Inhibits No-cGMP Signaling in a CD36- and CD47-Dependent Manner

Authors:
Miller TW, Isenberg JS, Shih HB, Wang Y, Roberts DD
Citation:
PLoS ONE. 2010;5(12): e15686. doi:10.1371/journal.pone.0015686
Epub:
Not Epub
Abstract:
Amyloid-β interacts with two cell surface receptors, CD36 and CD47, through which the matricellular protein thrombospondin-1...
Organism or Cell Type:
cell culture: BAEC and Jurkat
Citation Extract:
Miller TW, Isenberg JS, Shih HB, Wang Y, Roberts DD. Amyloid-β Inhibits No-cGMP Signaling in a CD36- and CD47-Dependent Manner. PLoS ONE. 2010;5(12): e15686. doi:10.1371/journal.pone.0015686.

An Essential and Evolutionarily Conserved Role of Protein Arginine Methyltransferase 1 for Adult Intestinal Stem Cells During Postembryonic Development

Authors:
Matsuda H, Shi YB
Citation:
Stem Cells. 2010 Sep 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Organ-specific adult stem cells are critical for the homeostasis of adult organs and organ repair and regeneration....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Matsuda H, Shi YB. An Essential and Evolutionarily Conserved Role of Protein Arginine Methyltransferase 1 for Adult Intestinal Stem Cells During Postembryonic Development. Stem Cells. 2010 Sep 16. [Epub ahead of print].

An essential role of Xenopus Foxi1a for ventral specification of the cephalic ectoderm during gastrulation.

Authors:
Matsuo-Takasaki M, Matsumura M, Sasai Y.
Citation:
Development. 2005 Sep;132(17):3885-94. Epub 2005 Aug 3.
Epub:
Not Epub
Abstract:
During gastrulation in Xenopus, the head ectoderm is subdivided into the central nervous system (CNS) anlage (neural plate) and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Matsuo-Takasaki M, Matsumura M, Sasai Y.. An essential role of Xenopus Foxi1a for ventral specification of the cephalic ectoderm during gastrulation.. Development. 2005 Sep;132(17):3885-94. Epub 2005 Aug 3..

Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD

Authors:
McClorey G, Moulton HM, Iversen PL, Fletcher S, Wilton SD
Citation:
Gene Ther. 2006 Oct;13(19):1373-81. Epub 2006 May 25
Epub:
Not Epub
Abstract:
Manipulation of pre-mRNA splicing by antisense oligonucleotides (AOs) offers considerable potential for a number of genetic...
Delivery Method:
Bathing primary cell culture, with and without peptide conjugates
Organism or Cell Type:
cell culture: primary myoblasts, golden retreiver DMD model
Citation Extract:
McClorey G, Moulton HM, Iversen PL, Fletcher S, Wilton SD. Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD. Gene Ther. 2006 Oct;13(19):1373-81. Epub 2006 May 25.

Aryl hydrocarbon receptor activation inhibits regenerative growth

Authors:
Mathew LK, Andreasen EA, Tanguay RL
Citation:
Mol Pharmacol. 2006 Jan;69(1):257-65. Epub 2005 Oct 7.
Epub:
Not Epub
Abstract:
There is considerable literature supporting the conclusion that inappropriate activation of the aryl hydrocarbon receptor (AHR...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mathew LK, Andreasen EA, Tanguay RL. Aryl hydrocarbon receptor activation inhibits regenerative growth. Mol Pharmacol. 2006 Jan;69(1):257-65. Epub 2005 Oct 7..

Aryl Phosphate Esters Within a Major PentaBDE Replacement Product Induce Cardiotoxicity in Developing Zebrafish Embryos: Potential Role of the Aryl Hydrocarbon Receptor

Authors:
McGee SP, Konstantinov A, Stapleton HM, Volz DC
Citation:
Toxicol Sci. 2013 Feb 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Firemaster(®) 550 (FM550) is an additive flame retardant formulation of brominated and aryl phosphate ester (APE) components...
Organism or Cell Type:
zebrafish
Citation Extract:
McGee SP, Konstantinov A, Stapleton HM, Volz DC. Aryl Phosphate Esters Within a Major PentaBDE Replacement Product Induce Cardiotoxicity in Developing Zebrafish Embryos: Potential Role of the Aryl Hydrocarbon Receptor. Toxicol Sci. 2013 Feb 1. [Epub ahead of print].

Atoh1a expression must be restricted by Notch signaling for effective morphogenesis of the posterior lateral line primordium in zebrafish

Authors:
Matsuda M, Chitnis AB
Citation:
Development. 2010 Oct;137(20):3477-87
Epub:
Not Epub
Abstract:
The posterior lateral line primordium (pLLp) migrates caudally, depositing neuromasts to establish the posterior lateral line...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Matsuda M, Chitnis AB. Atoh1a expression must be restricted by Notch signaling for effective morphogenesis of the posterior lateral line primordium in zebrafish. Development. 2010 Oct;137(20):3477-87.

B7-h1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis

Authors:
Mazanet MM, Hughes CC
Citation:
J Immunol. 2002 Oct 1;169(7):3581-8
Epub:
Not Epub
Abstract:
Human endothelial cells (ECs) provide costimulatory signals sufficient to activate resting memory T cells to produce IL-2 and...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture:human endothelial cells (ECs)
Citation Extract:
Mazanet MM, Hughes CC. B7-h1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis. J Immunol. 2002 Oct 1;169(7):3581-8.

Backbone Modification of Nucleic Acids: Synthesis, Structure and Therapeutic Applications

Authors:
Micklefield J
Citation:
Curr Med Chem. 2001 Aug;8(10):1157-79.
Epub:
Not Epub
Abstract:
Nucleic acids have been extensively modified by replacing the phosphodiester group or the whole sugar phosphodiester with...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Micklefield J. Backbone Modification of Nucleic Acids: Synthesis, Structure and Therapeutic Applications. Curr Med Chem. 2001 Aug;8(10):1157-79..

Bbs8, together with the planar cell polarity protein Vangl2, is required to establish left-right asymmetry in zebrafish

Authors:
May-Simera HL, Kai M, Hernandez V, Osborn DP, Tada M, Beales PL
Citation:
Dev Biol. 2010 Jul 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Laterality defects such as situs inversus are not uncommonly encountered in humans, either in isolation or as part of another...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
May-Simera HL, Kai M, Hernandez V, Osborn DP, Tada M, Beales PL. Bbs8, together with the planar cell polarity protein Vangl2, is required to establish left-right asymmetry in zebrafish. Dev Biol. 2010 Jul 16. [Epub ahead of print].

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