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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

The α-Tocopherol Transfer Protein Is Essential for Vertebrate Embryogenesis

Authors:
Miller GW, Ulatowski L, Labut EM, Lebold KM, Manor D, Atkinson J, Barton CL, Tanguay RL, Traber MG
Citation:
PLoS ONE. 2012;7(10):e47402. doi:10.1371/journal.pone.0047402
Epub:
Not Epub
Abstract:
The hepatic α-tocopherol transfer protein (TTP) is required for optimal α-tocopherol bioavailability in humans; mutations in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miller GW, Ulatowski L, Labut EM, Lebold KM, Manor D, Atkinson J, Barton CL, Tanguay RL, Traber MG. The α-Tocopherol Transfer Protein Is Essential for Vertebrate Embryogenesis. PLoS ONE. 2012;7(10):e47402. doi:10.1371/journal.pone.0047402.

The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism

Authors:
Merrick D, Chapin H, Baggs JE, Yu Z, Somlo S, Sun Z, Hogenesch JB, Caplan MJ
Citation:
Dev Cell. 2012 Jan 17;22(1):197-210. doi: 10.1016/j.devcel.2011.10.028. Epub 2011 Dec 15
Epub:
Not Epub
Abstract:
Mutations in Pkd1, encoding polycystin-1 (PC1), cause autosomal-dominant polycystic kidney disease (ADPKD). We show that the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Merrick D, Chapin H, Baggs JE, Yu Z, Somlo S, Sun Z, Hogenesch JB, Caplan MJ. The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism. Dev Cell. 2012 Jan 17;22(1):197-210. doi: 10.1016/j.devcel.2011.10.028. Epub 2011 Dec 15.

TNF{alpha}-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosylhomocysteine hydrolase

Authors:
Matthews RP, Lorent K, Mañoral-Mobias R, Huang Y, Gong W, Murray IV, Blair IA, Pack M
Citation:
Development. 2009 Mar;136(5):865-75
Epub:
Not Epub
Abstract:
Hepatic steatosis and liver degeneration are prominent features of the zebrafish ducttrip (dtp) mutant phenotype. Positional...
Organism or Cell Type:
zebrafish
Citation Extract:
Matthews RP, Lorent K, Mañoral-Mobias R, Huang Y, Gong W, Murray IV, Blair IA, Pack M. TNF{alpha}-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosylhomocysteine hydrolase. Development. 2009 Mar;136(5):865-75.

Toward defining the phosphoproteome of Xenopus laevis embryos

Authors:
McGivern JV, Swaney DL, Coon JJ, Sheets MD
Citation:
Dev Dyn. 2009 Jun;238(6):1433-43
Epub:
Not Epub
Abstract:
Phosphorylation is universally used for controlling protein function, but knowledge of the phosphoproteome in vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
McGivern JV, Swaney DL, Coon JJ, Sheets MD. Toward defining the phosphoproteome of Xenopus laevis embryos. Dev Dyn. 2009 Jun;238(6):1433-43.

Transcription factor onecut3 regulates intrahepatic biliary development in zebrafish

Authors:
Matthews RP, Lorent K, Pack M
Citation:
Dev Dyn. 2008 Jan;237(1):124-31
Epub:
Not Epub
Abstract:
Members of the onecut family of transcription factors play important roles in the development of the liver and pancreas. We...
Organism or Cell Type:
zebrafish
Citation Extract:
Matthews RP, Lorent K, Pack M. Transcription factor onecut3 regulates intrahepatic biliary development in zebrafish. Dev Dyn. 2008 Jan;237(1):124-31.

Two endothelin 1 effectors, hand2 and bapx1, pattern ventral pharyngeal cartilage and the jaw joint

Authors:
Miller CT, Yelon D, Stainier DY, Kimmel CB
Citation:
Development. 2003 Apr;130(7):1353-65
Epub:
Not Epub
Abstract:
A conserved endothelin 1 signaling pathway patterns the jaw and other pharyngeal skeletal elements in mice, chicks and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miller CT, Yelon D, Stainier DY, Kimmel CB. Two endothelin 1 effectors, hand2 and bapx1, pattern ventral pharyngeal cartilage and the jaw joint. Development. 2003 Apr;130(7):1353-65.

Unraveling tissue regeneration pathways using chemical genetics

Authors:
Mathew LK, Sengupta S, Kawakami A, Andreasen EA, Lohr CV, Loynes CA, Renshaw SA, Peterson RT, Tanguay RL
Citation:
J Biol Chem. 2007 Nov 30;282(48):35202-10. Epub 2007 Sep 11
Epub:
Not Epub
Abstract:
Identifying the molecular pathways that are required for regeneration remains one of the great challenges of regenerative...
Delivery Method:
Electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Mathew LK, Sengupta S, Kawakami A, Andreasen EA, Lohr CV, Loynes CA, Renshaw SA, Peterson RT, Tanguay RL. Unraveling tissue regeneration pathways using chemical genetics. J Biol Chem. 2007 Nov 30;282(48):35202-10. Epub 2007 Sep 11.

Variations in Amino Acid Composition of Antisense Peptide-Phosphorodiamidate Morpholino Oligomer Affect Potency Against Escherichia coli in vitro and in vivo

Authors:
Mellbye BL, Puckett SE, Tilley LD, Iversen PL, Geller BL
Citation:
Antimicrob Agents Chemother. 2009 Feb;53(2):525-30. Epub 2008 Nov 17.
Epub:
Not Epub
Abstract:
The potency of antisense peptide-phosphorodiamidate morpholino oligomers (PPMO) was improved by varying peptide composition. An...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Escherichia coli
Citation Extract:
Mellbye BL, Puckett SE, Tilley LD, Iversen PL, Geller BL. Variations in Amino Acid Composition of Antisense Peptide-Phosphorodiamidate Morpholino Oligomer Affect Potency Against Escherichia coli in vitro and in vivo. Antimicrob Agents Chemother. 2009 Feb;53(2):525-30. Epub 2008 Nov 17..

Wnt ligands signal in a cooperative manner to promote foregut organogenesis

Authors:
Miller MF, Cohen ED, Baggs JE, Lu MM, Hogenesch JB, Morrisey EE
Citation:
Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15348-53. Epub 2012 Sep 4
Epub:
Not Epub
Abstract:
Endoderm-mesenchyme cross-talk is a central process in the development of foregut-derived organs. How signaling pathways...
Delivery Method:
oligo bathing
Organism or Cell Type:
Mouse lung explants
Citation Extract:
Miller MF, Cohen ED, Baggs JE, Lu MM, Hogenesch JB, Morrisey EE. Wnt ligands signal in a cooperative manner to promote foregut organogenesis. Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15348-53. Epub 2012 Sep 4.

Wnt11r is required for cranial neural crest migration

Authors:
Matthews HK, Broders-Bondon F, Thiery JP, Mayor R
Citation:
Dev Dyn. 2008 Oct 21;237(11):3404-3409. [Epub ahead of print]
Epub:
Not Epub
Abstract:
wnt11r is a recently identified member of the Wnt family of genes, which has been proposed to be the true Xenopus homologue to...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Matthews HK, Broders-Bondon F, Thiery JP, Mayor R. Wnt11r is required for cranial neural crest migration. Dev Dyn. 2008 Oct 21;237(11):3404-3409. [Epub ahead of print].

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