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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Identification of RNA binding motif proteins essential for cardiovascular development

Authors:
Maragh S, Miller RA, Bessling SL, McGaughey DM, Wessels MW, de Graaf B, Stone EA, Bertoli-Avella AM, Gearhart JD, Fisher S, McCallion AS
Citation:
BMC Dev Biol. 2011;11:62 doi:10.1186/1471-213X-11-62
Epub:
Not Epub
Abstract:
Background We recently identified Rbm24 as a novel gene expressed during mouse cardiac development. Due to its tightly...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maragh S, Miller RA, Bessling SL, McGaughey DM, Wessels MW, de Graaf B, Stone EA, Bertoli-Avella AM, Gearhart JD, Fisher S, McCallion AS. Identification of RNA binding motif proteins essential for cardiovascular development . BMC Dev Biol. 2011;11:62 doi:10.1186/1471-213X-11-62.

Initial investigations of 99m Tc-labeled morpholinos for radiopharmaceutical applications

Authors:
Mang'era KO, Liu G, Yi W, Zhang Y, Liu N, Gupta S, Rusckowski M, Hnatowich DJ
Citation:
Eur J Nucl Med 2001 Nov;28(11):1682-9
Epub:
Not Epub
Abstract:
This laboratory is evaluating phosphorothioate deoxyribonucleic acids (DNAs) and peptide nucleic acids (PNAs) for a variety of...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Mang'era KO, Liu G, Yi W, Zhang Y, Liu N, Gupta S, Rusckowski M, Hnatowich DJ. Initial investigations of 99m Tc-labeled morpholinos for radiopharmaceutical applications. Eur J Nucl Med 2001 Nov;28(11):1682-9.

Loss of Function of Glucocerebrosidase GBA2 Is Responsible for Motor Neuron Defects in Hereditary Spastic Paraplegia

Authors:
Martin E, Schüle R, Smets K, Rastetter A, Boukhris A, Loureiro JL, Gonzalez MA, Mundwiller E, Deconinck T, Wessner M, Jornea L, Oteyza AC, Durr A, Martin JJ, Schöls L, Mhiri C, Lamari F, Züchner S, De Jonghe P, Kabashi E, Brice A, Stevanin G
Citation:
Am J Hum Genet. 2013;[Epub ahead of print] doi:10.1016/j.ajhg.2012.11.021
Epub:
Not Epub
Abstract:
Spastic paraplegia 46 refers to a locus mapped to chromosome 9 that accounts for a complicated autosomal-recessive form of...
Organism or Cell Type:
zebrafish
Citation Extract:
Martin E, Schüle R, Smets K, Rastetter A, Boukhris A, Loureiro JL, Gonzalez MA, Mundwiller E, Deconinck T, Wessner M, Jornea L, Oteyza AC, Durr A, Martin JJ, Schöls L, Mhiri C, Lamari F, Züchner S, De Jonghe P, Kabashi E, Brice A, Stevanin G. Loss of Function of Glucocerebrosidase GBA2 Is Responsible for Motor Neuron Defects in Hereditary Spastic Paraplegia. Am J Hum Genet. 2013;[Epub ahead of print] doi:10.1016/j.ajhg.2012.11.021.

Loss of the ciliary kinase Nek8 causes left-right asymmetry defects

Authors:
Manning DK, Sergeev M, van Heesbeen RG, Wong MD, Oh JH, Liu Y, Henkelman RM, Drummond I, Shah JV, Beier DR
Citation:
J Am Soc Nephrol. 2013 Jan;24(1):100-12. doi: 10.1681/ASN.2012050490
Epub:
Not Epub
Abstract:
A missense mutation in mouse Nek8, which encodes a ciliary kinase, produces the juvenile cystic kidneys (jck) model of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Manning DK, Sergeev M, van Heesbeen RG, Wong MD, Oh JH, Liu Y, Henkelman RM, Drummond I, Shah JV, Beier DR. Loss of the ciliary kinase Nek8 causes left-right asymmetry defects. J Am Soc Nephrol. 2013 Jan;24(1):100-12. doi: 10.1681/ASN.2012050490.

Maturin is a novel protein required for differentiation during primary neurogenesis

Authors:
Martinez-De Luna RI, Ku RY, Lyou Y, Zuber ME
Citation:
Dev Biol. 2013 Oct 1. doi:pii: S0012-1606(13)00514-9. 10.1016/j.ydbio.2013.09.028. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Proliferation and differentiation are tightly controlled during neural development. In the embryonic neural plate, primary...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Martinez-De Luna RI, Ku RY, Lyou Y, Zuber ME. Maturin is a novel protein required for differentiation during primary neurogenesis. Dev Biol. 2013 Oct 1. doi:pii: S0012-1606(13)00514-9. 10.1016/j.ydbio.2013.09.028. [Epub ahead of print].

Micro-injection of Morpholino Oligonucleotides for Depleting Securin in Mouse Oocytes

Authors:
Marangos P
Citation:
Meth Molec Biol. 2013;957:153-62. doi:10.1007/978-1-62703-191-2_10
Epub:
Not Epub
Abstract:
Gene silencing techniques have brought new insights into mammalian oocyte and embryo development. More specifically, the use of...
Link:
https://link.springer.com/protocol/10.1007/978-1-62703-191-2_10
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Marangos P. Micro-injection of Morpholino Oligonucleotides for Depleting Securin in Mouse Oocytes. Meth Molec Biol. 2013;957:153-62. doi:10.1007/978-1-62703-191-2_10.

Myo1e Impairment Results in Actin Reorganization, Podocyte Dysfunction, and Proteinuria in Zebrafish and Cultured Podocytes

Authors:
Mao J, Wang D, Mataleena P, He B, Niu D, Katayama K, Xu X, Ojala JR, Wang W, Shu Q, Do L, Liu A, Pikkarainen T, Patrakka J, Tyrggvason K
Citation:
PLoS ONE. 2013;8(8):e72750. doi:10.1371/journal.pone.0072750
Epub:
Not Epub
Abstract:
Background Podocytes serve as an important constituent of the glomerular filtration barrier. Recently, we and others identified...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mao J, Wang D, Mataleena P, He B, Niu D, Katayama K, Xu X, Ojala JR, Wang W, Shu Q, Do L, Liu A, Pikkarainen T, Patrakka J, Tyrggvason K. Myo1e Impairment Results in Actin Reorganization, Podocyte Dysfunction, and Proteinuria in Zebrafish and Cultured Podocytes. PLoS ONE. 2013;8(8):e72750. doi:10.1371/journal.pone.0072750.

ojoplano-mediated basal constriction is essential for optic cup morphogenesis

Authors:
Martinez-Morales JR, Rembold M, Greger K, Simpson JC, Brown KE, Quiring R, Pepperkok R, Martin-Bermudo MD, Himmelbauer H, Wittbrodt J
Citation:
Development. 2009 Jul;136(13):2165-75
Epub:
Not Epub
Abstract:
Although the vertebrate retina is a well-studied paradigm for organogenesis, the morphogenetic mechanisms that carve the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Martinez-Morales JR, Rembold M, Greger K, Simpson JC, Brown KE, Quiring R, Pepperkok R, Martin-Bermudo MD, Himmelbauer H, Wittbrodt J. ojoplano-mediated basal constriction is essential for optic cup morphogenesis. Development. 2009 Jul;136(13):2165-75.

Patterning the forebrain: FoxA4a/Pintallavis and Xvent2 determine the posterior limit of Xanf1 expression in the neural plate

Authors:
Martynova N, Eroshkin F, Ermakova G, Bayramov A, Gray J, Grainger R, Zaraisky A
Citation:
Development. 2004 May;131(10):2329-38
Epub:
Not Epub
Abstract:
During early development of the nervous system in vertebrates, expression of the homeobox gene Anf/Hesx1/Rpx is restricted to...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Martynova N, Eroshkin F, Ermakova G, Bayramov A, Gray J, Grainger R, Zaraisky A. Patterning the forebrain: FoxA4a/Pintallavis and Xvent2 determine the posterior limit of Xanf1 expression in the neural plate. Development. 2004 May;131(10):2329-38.

Plakoglobin has both structural and signalling roles in zebrafish development

Authors:
Martin ED, Moriarty MA, Byrnes L, Grealy M
Citation:
Dev Biol. 2008 Dec 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Plakoglobin, or gamma-catenin, is found in both desmosomes and adherens junctions and participates in Wnt signalling. Mutations...
Organism or Cell Type:
zebrafish
Citation Extract:
Martin ED, Moriarty MA, Byrnes L, Grealy M. Plakoglobin has both structural and signalling roles in zebrafish development. Dev Biol. 2008 Dec 10. [Epub ahead of print].

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