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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
There are 12095 scientific papers returned from the database with the search filters currently being used below.
DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC
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Citation:
Cell. 2010 Sep 17;142(6):930-42 Epub:
Not Epub Abstract:
Although genome-wide hypomethylation is a hallmark of many cancers, roles for active DNA demethylation during tumorigenesis are... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Rai K, Sarkar S, Broadbent TJ, Voas M, Grossmann KF, Nadauld LD, Dehghanizadeh S, Hagos FT, Li Y, Toth RK, Chidester S, Bahr TM, Johnson WE, Sklow B, Burt R, Cairns BR, Jones DA. DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC. Cell. 2010 Sep 17;142(6):930-42. |
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
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Citation:
Cell. 2008 Dec 26;135(7):1201-12 Epub:
Not Epub Abstract:
Evidence for active DNA demethylation in vertebrates is accumulating, but the mechanisms and enzymes remain unclear. Using... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell. 2008 Dec 26;135(7):1201-12. |
Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish
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Citation:
Genes Dev. 2007 Feb 1;21(3):261-6 Epub:
Not Epub Abstract:
The roles of DNA methyltransferase-2 (DNMT2) enzymes are controversial; whether DNMT2 functions primarily as a nuclear DNA... Organism or Cell Type:
zebrafish Citation Extract: Rai K, Chidester S, Zavala CV, Manos EJ, James SR, Karpf AR, Jones DA, Cairns BR. Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish. Genes Dev. 2007 Feb 1;21(3):261-6. |
Dnmt3 and G9a cooperate for tissue-specific development in zebrafish
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Citation:
J Biol Chem. 2009 Nov 29. [Epub ahead of print] Epub:
Not Epub Abstract:
Although DNA methylation is critical for proper embryonic and tissue-specific development, how different DNA methyltransferases... Organism or Cell Type:
zebrafish Citation Extract: Rai K, Jafri IF, Chidester S, James SR, Karpf AR, Cairns BR, Jones DA. Dnmt3 and G9a cooperate for tissue-specific development in zebrafish. J Biol Chem. 2009 Nov 29. [Epub ahead of print]. |
Endocrine-committed progenitor cells retain their differentiation potential in the absence of neurogenin-3 expression
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Citation:
Biochem Biophys Res Commun. 2010 Jun 11;396(4):1036-41. doi: 10.1016/j.bbrc.2010.05.058. Epub 2010 May 13 Epub:
Not Epub Abstract:
Neurogenin-3 (ngn-3) expression is critical for endocrine development in the developing pancreas. We found that when ngn-3 was... Delivery Method:
oligo bathing Organism or Cell Type:
Mouse pancreas explant Citation Extract: Prasadan K, Tulachan S, Guo P, Shiota C, Shah S, Gittes G. Endocrine-committed progenitor cells retain their differentiation potential in the absence of neurogenin-3 expression. Biochem Biophys Res Commun. 2010 Jun 11;396(4):1036-41. doi: 10.1016/j.bbrc.2010.05.058. Epub 2010 May 13. |
Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish
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Citation:
Dev Biol. 2008 Jun 1;318(1):52-64. Epub 2008 Mar 20 Epub:
Not Epub Abstract:
The zebrafish enteric nervous system (ENS), like those of all other vertebrate species, is principally derived from the vagal... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Reichenbach B, Delalande JM, Kolmogorova E, Prier A, Nguyen T, Smith CM, Holzschuh J, Shepherd IT. Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish. Dev Biol. 2008 Jun 1;318(1):52-64. Epub 2008 Mar 20. |
Exploring Zebrafish Genomic, Functional and Phenotypic Data Using ZFIN
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Citation:
Curr Protoc Bioinformatics. 2010 Sep;Chapter 1:Unit1.18 Epub:
Not Epub Abstract:
The zebrafish model organism database (ZFIN) provides a Web resource of zebrafish genomic, genetic, developmental, and... Organism or Cell Type:
zebrafish Citation Extract: Ramachandran S, Ruef B, Pich C, Sprague J. Exploring Zebrafish Genomic, Functional and Phenotypic Data Using ZFIN. Curr Protoc Bioinformatics. 2010 Sep;Chapter 1:Unit1.18. |
Functional analysis of BBS3 A89V that results in non-syndromic retinal degeneration
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Citation:
Hum Mol Genet. 2011 Jan 31. [Epub ahead of print] Epub:
Not Epub Abstract:
Bardet-Biedl Syndrome (BBS) is a syndromic form of retinal degeneration. Recently, homozygosity mapping with a consanguineous... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Pretorius PR, Aldahmesh MA, Alkuraya FS, Sheffield VC, Slusarski DC. Functional analysis of BBS3 A89V that results in non-syndromic retinal degeneration. Hum Mol Genet. 2011 Jan 31. [Epub ahead of print]. |
Germline gain-of-function mutations in RAF1 cause Noonan syndrome
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Citation:
Nat Genet. 2007 Aug;39(8):1013-7. Epub 2007 Jul 1. Epub:
Not Epub Abstract:
Noonan syndrome is characterized by short stature, facial dysmorphia and a wide spectrum of congenital heart defects. Mutations... Organism or Cell Type:
zebrafish Citation Extract: Razzaque MA, Nishizawa T, Komoike Y, Yagi H, Furutani M, Amo R, Kamisago M, Momma K, Katayama H, Nakagawa M, Fujiwara Y, Matsushima M, Mizuno K, Tokuyama M, Hirota H, Muneuchi J, Higashinakagawa T, Matsuoka R. Germline gain-of-function mutations in RAF1 cause Noonan syndrome. Nat Genet. 2007 Aug;39(8):1013-7. Epub 2007 Jul 1.. |
Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas
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Citation:
Diabetes. 2002 Nov;51(11):3229-36 Epub:
Not Epub Abstract:
The embryonic pancreas is thought to develop from pluripotent endodermal cells that give rise to endocrine and exocrine cells.... Delivery Method:
oligo bathing Organism or Cell Type:
Mouse embryonic tissue Citation Extract: Prasadan K, Daume E, Preuett B, Spilde T, Bhatia A, Kobayashi H, Hembree M, Manna P, Gittes GK. Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas. Diabetes. 2002 Nov;51(11):3229-36. |