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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12208 scientific papers returned from the database with the search filters currently being used below.
There are 12208 scientific papers returned from the database with the search filters currently being used below.
The ezrin Gene Regulates Early Cardiac Morphogenesis and Contractile Function in Zebrafish Through the Coordinated Regulation of Apoptosis, Calcium Homeostasis, and the MAPK Signaling Pathway
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Citation:
Cells. 2026; 15(12):1046. https://doi.org/10.3390/cells15121046 Epub:
Not Epub Abstract:
Ezrin, expressed by the EZR gene, is a member of the ERM protein family that connects the plasma membrane to the actin... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lv J, Zeng T, Liao B, Liu L, Xiong L, Xie H, Zhu L, Jiang X, Zhong Z, Xie H. The ezrin Gene Regulates Early Cardiac Morphogenesis and Contractile Function in Zebrafish Through the Coordinated Regulation of Apoptosis, Calcium Homeostasis, and the MAPK Signaling Pathway. Cells. 2026; 15(12):1046. https://doi.org/10.3390/cells15121046. |
An aquaglyceroporin governs cellular water and CO2 conductance relevant for vesicular mineral formation in a marine calcifier
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Citation:
Proc Natl Acad Sci U S A. 2026 Jun 16;123(24):e2524614123. doi: 10.1073/pnas.2524614123. Epub 2026 Jun 8. PMID: 42258730 Epub:
Not Epub Abstract:
Many marine organisms generate biominerals by endocytotic uptake of seawater which is modified within calcifying cells to... Delivery Method:
microinjection Organism or Cell Type:
sea urchin larvae Citation Extract: Matt AS, Tetzlaff S, Jonusaite S, Quijada-Rodriguez A, Schewe M, Cordeiro S, Weihrauch D, Hu MY. An aquaglyceroporin governs cellular water and CO2 conductance relevant for vesicular mineral formation in a marine calcifier. Proc Natl Acad Sci U S A. 2026 Jun 16;123(24):e2524614123. doi: 10.1073/pnas.2524614123. Epub 2026 Jun 8. PMID: 42258730. |
ZL006 Treatment Reduces Inflammation, Oxidative Stress, and Brain Aβ1–42 Accumulation and Rescues the Loss of PSD95 Synaptic Marker in Familial Alzheimer’s Disease-Associated psen1-Deficient Zebrafish Model
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Citation:
International Journal of Molecular Sciences. 2026; 27(11):4992. https://doi.org/10.3390/ijms27114992 Epub:
Not Epub Abstract:
Familial Alzheimer’s disease (FAD) is a rare form of Alzheimer’s. FAD is mainly caused by one or multiple mutations in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ricci S, Benuzzi M, Fazzina M, Cacialli P. ZL006 Treatment Reduces Inflammation, Oxidative Stress, and Brain Aβ1–42 Accumulation and Rescues the Loss of PSD95 Synaptic Marker in Familial Alzheimer’s Disease-Associated psen1-Deficient Zebrafish Model. International Journal of Molecular Sciences. 2026; 27(11):4992. https://doi.org/10.3390/ijms27114992. |
A Real-World Target Trial Emulation of Eteplirsen, Casimersen, and Golodirsen to Evaluate Survival Among Patients with Duchenne Muscular Dystrophy
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Citation:
Adv Ther. 2026 Jun 6. doi: 10.1007/s12325-026-03609-0. Epub ahead of print. PMID: 42250075 Epub:
Not Epub Abstract:
Introduction: Real-world data are needed to understand the treatment effect of eteplirsen, casimersen, and golodirsen (... Delivery Method:
intravenous (i.v.) infusion Organism or Cell Type:
human Citation Extract: Dharmarajan S, Grabich S, Baxter R, Nadkar A, Schermer C. A Real-World Target Trial Emulation of Eteplirsen, Casimersen, and Golodirsen to Evaluate Survival Among Patients with Duchenne Muscular Dystrophy. Adv Ther. 2026 Jun 6. doi: 10.1007/s12325-026-03609-0. Epub ahead of print. PMID: 42250075. |
A Real-World Target Trial Emulation of Eteplirsen, Casimersen, and Golodirsen to Evaluate Survival Among Patients with Duchenne Muscular Dystrophy
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Citation:
Adv Ther. 2026 Jun 6. doi: 10.1007/s12325-026-03609-0. Epub ahead of print. PMID: 42250075 Epub:
Not Epub Abstract:
Introduction: Real-world data are needed to understand the treatment effect of eteplirsen, casimersen, and golodirsen (... Delivery Method:
intravenous (i.v.) infusion Organism or Cell Type:
human Citation Extract: Dharmarajan S, Grabich S, Baxter R, Nadkar A, Schermer C. A Real-World Target Trial Emulation of Eteplirsen, Casimersen, and Golodirsen to Evaluate Survival Among Patients with Duchenne Muscular Dystrophy. Adv Ther. 2026 Jun 6. doi: 10.1007/s12325-026-03609-0. Epub ahead of print. PMID: 42250075. |
A Real-World Target Trial Emulation of Eteplirsen, Casimersen, and Golodirsen to Evaluate Survival Among Patients with Duchenne Muscular Dystrophy
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Citation:
Adv Ther. 2026 Jun 6. doi: 10.1007/s12325-026-03609-0. Epub ahead of print. PMID: 42250075 Epub:
Not Epub Abstract:
Introduction: Real-world data are needed to understand the treatment effect of eteplirsen, casimersen, and golodirsen (... Delivery Method:
intravenous (i.v.) infusion Organism or Cell Type:
human Citation Extract: Dharmarajan S, Grabich S, Baxter R, Nadkar A, Schermer C. A Real-World Target Trial Emulation of Eteplirsen, Casimersen, and Golodirsen to Evaluate Survival Among Patients with Duchenne Muscular Dystrophy. Adv Ther. 2026 Jun 6. doi: 10.1007/s12325-026-03609-0. Epub ahead of print. PMID: 42250075. |
Gene body methylation suppresses intragenic transcription and permits epigenetic inheritance in a cnidarian
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Citation:
Nat Ecol Evol. 2026 Jun 2. doi: 10.1038/s41559-026-03090-6. Epub ahead of print. PMID: 42231006 Epub:
Not Epub Abstract:
Across invertebrates, DNA methylation is largely restricted to the bodies of highly and constitutively expressed genes. This... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (starlet sea anemone) Citation Extract: Xu L, Heery R, Baranasic D, Žunar B, Segura Campaña A, Ovchinnikov V, Lenhard B, de Mendoza A. Gene body methylation suppresses intragenic transcription and permits epigenetic inheritance in a cnidarian. Nat Ecol Evol. 2026 Jun 2. doi: 10.1038/s41559-026-03090-6. Epub ahead of print. PMID: 42231006. |
Heme oxygenase 1 activity mediates red blood cell clearance and tail fin regeneration in zebrafish larvae
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Citation:
Sci Rep. 2026 Jun 2;16(1):17157. doi: 10.1038/s41598-026-54996-x. PMID: 42230891 Epub:
Not Epub Abstract:
Tissue injury triggers a tightly regulated cascade of events that transition from inflammation to resolution and ultimately... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Mirza A, Crawte S, Muñoz-Montecinos C, Mukherjee S, Lieschke GJ, Allende ML, Morales Castro RA. Heme oxygenase 1 activity mediates red blood cell clearance and tail fin regeneration in zebrafish larvae. Sci Rep. 2026 Jun 2;16(1):17157. doi: 10.1038/s41598-026-54996-x. PMID: 42230891. |
CDKL1 variants affecting ciliary formation predispose to thoracic aortic aneurysm and dissection
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Citation:
J Clin Invest. 2025 Oct 7;135(23):e186287. doi: 10.1172/JCI186287. PMID: 41056017; PMCID: PMC12646653 Epub:
Not Epub Abstract:
Genetic factors are fundamental in the etiology of thoracic aortic aneurysm and dissection (TAAD), but the genetic cause is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nauth T, Philipp M, Renner S, Burkhalter MD, Schüler H, Saygi C, Händler K, Siebels B, Busch A, Mair T, Rickassel V, Deden S, Hoffer K, Olfe J, Mir TS, von Kodolitsch Y, Girdauskas E, Rybczynski M, Kriegs M, Voß H, Sauvigny T, Spielmann M, Alawi M, Krasemann S, Kubisch C, Demal TJ, Rosenberger G. CDKL1 variants affecting ciliary formation predispose to thoracic aortic aneurysm and dissection. J Clin Invest. 2025 Oct 7;135(23):e186287. doi: 10.1172/JCI186287. PMID: 41056017; PMCID: PMC12646653. |
A protein interactome for the last eukaryotic common ancestor illuminates the biochemical basis of modern genetic diseases
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Citation:
Cell Genom. 2026 May 27:101254. doi: 10.1016/j.xgen.2026.101254. Epub ahead of print. PMID: 42202782 Epub:
Not Epub Abstract:
All eukaryotes share a single-celled ancestor from ∼1.5 to 1.8 billion years ago, the so-called last eukaryotic common ancestor... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Cox RM, Papoulas O, Shril S, Lee C, Gardner TP, Ansari ZT, Battenhouse AM, Lee M, Drew K, McWhite CD, Yang D, Leggere JC, Durand D, Hildebrandt F, Wallingford JB, Marcotte EM. A protein interactome for the last eukaryotic common ancestor illuminates the biochemical basis of modern genetic diseases. Cell Genom. 2026 May 27:101254. doi: 10.1016/j.xgen.2026.101254. Epub ahead of print. PMID: 42202782. |