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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9420 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Cul4a promotes zebrafish primitive erythropoiesis via upregulating scl and gata1 expression

Authors:
Yang F, Hu H, Liu Y, Shao M, Shao C, Gong Y
Citation:
Cell Death Dis. 2019;10(6):388. doi:10.1038/s41419-019-1629-7
Abstract:
CUL4A and CUL4B are closely related members in Cullin family and can each assemble a Cullin-RING E3 ligase complex (Cullin-RING...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang F, Hu H, Liu Y, Shao M, Shao C, Gong Y. Cul4a promotes zebrafish primitive erythropoiesis via upregulating scl and gata1 expression. Cell Death Dis. 2019;10(6):388. doi:10.1038/s41419-019-1629-7.

CiliaCarta: An integrated and validated compendium of ciliary genes

Authors:
van Dam TJP, Kennedy J, van der Lee R, de Vrieze E, Wunderlich KA, Rix S, Dougherty GW, Lambacher NJ, Li C, Jensen VL, Leroux MR, Hjeij R, Horn N, Texier Y, Wissinger Y, van Reeuwijk J, Wheway G, Knapp B, Scheel JF, Franco B, Mans DA, van Wijk E, Képès F, Slaats GG, Toedt G, Kremer H, Omran H, Szymanska K, Koutroumpas K, Ueffing M, Nguyen T-MT, Letteboer SJF, Oud MM, van Beersum SEC, Schmidts M, Beales PL, Lu Q, Giles RH, Szklarczyk R, Russell RB, Gibson TJ, Johnson CA, Blacque OE, Wolfrum U, Boldt K, Roepman R, Hernandez-Hernandez V, Huynen MA
Citation:
PLoS ONE. 2019;14(5):e0216705. doi:10.1371/journal.pone.0216705
Abstract:
The cilium is an essential organelle at the surface of mammalian cells whose dysfunction causes a wide range of genetic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van Dam TJP, Kennedy J, van der Lee R, de Vrieze E, Wunderlich KA, Rix S, Dougherty GW, Lambacher NJ, Li C, Jensen VL, Leroux MR, Hjeij R, Horn N, Texier Y, Wissinger Y, van Reeuwijk J, Wheway G, Knapp B, Scheel JF, Franco B, Mans DA, van Wijk E, Képès F, Slaats GG, Toedt G, Kremer H, Omran H, Szymanska K, Koutroumpas K, Ueffing M, Nguyen T-MT, Letteboer SJF, Oud MM, van Beersum SEC, Schmidts M, Beales PL, Lu Q, Giles RH, Szklarczyk R, Russell RB, Gibson TJ, Johnson CA, Blacque OE, Wolfrum U, Boldt K, Roepman R, Hernandez-Hernandez V, Huynen MA. CiliaCarta: An integrated and validated compendium of ciliary genes. PLoS ONE. 2019;14(5):e0216705. doi:10.1371/journal.pone.0216705.

Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis

Authors:
Burkhalter MD, Sridhar A, Sampaio P, Jacinto R, Burczyk MS, Donow C, Angenendt M, Investigators CNFCHD, Hempel M, Walther P, Pennekamp P, Omran H, Lopes SS, Ware SM, Philipp M
Citation:
J Clin Invest. 2019 May 16;130. pii: 98890. doi: 10.1172/JCI98890
Abstract:
About 1% of all newborns are affected by congenital heart disease (CHD). Recent findings identify aberrantly functioning cilia...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burkhalter MD, Sridhar A, Sampaio P, Jacinto R, Burczyk MS, Donow C, Angenendt M, Investigators CNFCHD, Hempel M, Walther P, Pennekamp P, Omran H, Lopes SS, Ware SM, Philipp M. Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis. J Clin Invest. 2019 May 16;130. pii: 98890. doi: 10.1172/JCI98890.

Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes

Authors:
Chen YY, Harris MP, Levesque MP, Nüsslein-Volhard C, Sonawane M
Citation:
Mech Dev. 2012 Mar-Jun;129(1-4):13-23. doi: 10.1016/j.mod.2012.03.003. Epub 2012 Apr 12
Abstract:
In vertebrates, the dorso-ventral (DV) axis is defined by the combinatorial action of localised Wnt, FGF and Nodal signalling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen YY, Harris MP, Levesque MP, Nüsslein-Volhard C, Sonawane M. Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes. Mech Dev. 2012 Mar-Jun;129(1-4):13-23. doi: 10.1016/j.mod.2012.03.003. Epub 2012 Apr 12.

Ninjurin1 regulates striated muscle growth and differentiation

Authors:
Kny M, Csályi KD, Klaeske K, Busch K, Meyer AM, Merks AM, Darm K, Dworatzek E, Fliegner D, Baczko I, Regitz-Zagrosek V, Butter C, Luft FC, Panáková D, Fielitz J
Citation:
PLoS ONE. 2019;14(5):e0216987. doi:10.1371/journal.pone.0216987
Abstract:
Chronic pressure overload due to aortic valve stenosis leads to pathological cardiac hypertrophy and heart failure. Hypertrophy...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kny M, Csályi KD, Klaeske K, Busch K, Meyer AM, Merks AM, Darm K, Dworatzek E, Fliegner D, Baczko I, Regitz-Zagrosek V, Butter C, Luft FC, Panáková D, Fielitz J. Ninjurin1 regulates striated muscle growth and differentiation. PLoS ONE. 2019;14(5):e0216987. doi:10.1371/journal.pone.0216987.

MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling

Authors:
Watterston C, Zeng L, Onabadejo A, Childs SJ
Citation:
PLoS Genet. 2019 May 15;15(5):e1008163. doi: 10.1371/journal.pgen.1008163. [Epub ahead of print]
Abstract:
As small regulatory transcripts, microRNAs (miRs) act as genetic 'fine tuners' of posttranscriptional events, and as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Watterston C, Zeng L, Onabadejo A, Childs SJ. MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling. PLoS Genet. 2019 May 15;15(5):e1008163. doi: 10.1371/journal.pgen.1008163. [Epub ahead of print].

Quantitative measurements of chromatin modification dynamics during zygotic genome activation

Authors:
Sato Y, Hilbert L, Oda H, Wan Y, Heddleston JM, Chew T-L, Zaburdaev V, Keller P, Lionnet T, Vastenhouw N, Hiroshi Kimura H
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/601393
Abstract:
Histone posttranslational modifications (PTMs) are key gene expression regulators, but their rapid dynamics during development...
Organism or Cell Type:
zebrafish
Citation Extract:
Sato Y, Hilbert L, Oda H, Wan Y, Heddleston JM, Chew T-L, Zaburdaev V, Keller P, Lionnet T, Vastenhouw N, Hiroshi Kimura H. Quantitative measurements of chromatin modification dynamics during zygotic genome activation. bioRxiv. 2019;[preprint] doi:10.1101/601393.

A reference map of the human protein interactome

Authors:
Luck K, Kim D-K, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Cote AG, Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF, Kishore N, Knapp JJ, Kovács IA, Lemmens I, Mee MW, Mellor JC, Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A, Babor M, Balcha D, Basha O, Bowman-Colin C, Chin S-F, Choi SG, Colabella C, Coppin G, D’Amata C, De Ridder D, De Rouck S, Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A, Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van Lieshout N, <authors omitted - space limit>Taşan M, Tejeda A, Twizere J-C, Wang Y, Weatheritt RJ, Weile J, Xia Y, Yang X, Yeger-Lotem E, Zhong Q, Aloy P, Bader GD, De Las Rivas J, Gaudet S, Hao T, Rak J, Tavernier J, Tropepe V, Hill DE, Vidal M, Roth FP, Calderwood MA.
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/605451
Abstract:
Global insights into cellular organization and function require comprehensive understanding of interactome networks. Similar to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Luck K, Kim D-K, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Cote AG, Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF, Kishore N, Knapp JJ, Kovács IA, Lemmens I, Mee MW, Mellor JC, Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A, Babor M, Balcha D, Basha O, Bowman-Colin C, Chin S-F, Choi SG, Colabella C, Coppin G, D’Amata C, De Ridder D, De Rouck S, Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A, Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van Lieshout N, <authors omitted - space limit>Taşan M, Tejeda A, Twizere J-C, Wang Y, Weatheritt RJ, Weile J, Xia Y, Yang X, Yeger-Lotem E, Zhong Q, Aloy P, Bader GD, De Las Rivas J, Gaudet S, Hao T, Rak J, Tavernier J, Tropepe V, Hill DE, Vidal M, Roth FP, Calderwood MA. . A reference map of the human protein interactome. bioRxiv. 2019;[preprint] doi:10.1101/605451.

Stasimon contributes to the loss of sensory synapses and motor neuron death in a mouse model of spinal muscular atrophy

Authors:
Simon CM, Van Alstyne M, Lotti F, Bianchetti E, Tisdale S, Mentis GZ, Pellizzoni L
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/608513
Abstract:
Reduced expression of the SMN protein causes spinal muscular atrophy (SMA) - an inherited neurodegenerative disease...
Organism or Cell Type:
cell culture: NIH3T3
Citation Extract:
Simon CM, Van Alstyne M, Lotti F, Bianchetti E, Tisdale S, Mentis GZ, Pellizzoni L. Stasimon contributes to the loss of sensory synapses and motor neuron death in a mouse model of spinal muscular atrophy. bioRxiv. 2019;[preprint] doi:10.1101/608513.

NCBP2-mediated apoptosis contributes to developmental defects of the schizophrenia-associated 3q29 deletion

Authors:
Singh MD, Jensen M, Lasser M, Huber E, Yusuff T, Pizzo L, Lifschutz B, Desai I, Kubina A, Yennawar S, Kim S, Iyer J, Rincon-Limas DE, Lowery LA, Girirajan S
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/614750
Abstract:
The chromosome 3q29 deletion confers >40-fold risk for schizophrenia and related neurodevelopmental disorders. Here, we used...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Singh MD, Jensen M, Lasser M, Huber E, Yusuff T, Pizzo L, Lifschutz B, Desai I, Kubina A, Yennawar S, Kim S, Iyer J, Rincon-Limas DE, Lowery LA, Girirajan S. NCBP2-mediated apoptosis contributes to developmental defects of the schizophrenia-associated 3q29 deletion. bioRxiv. 2019:[preprint] doi:10.1101/614750.

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