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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10101 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling

Authors:
Mancini A, Howard SR, Marelli F, Cabrera CP, Barnes MR, Sternberg MJE, Leprovots M, Hadjidemetriou I, Monti E, David A, Wehkalampi K, Oleari R, Lettieri A, Vezzoli V, Vassart G, Cariboni A, Bonomi M, Garcia MI, Guasti L, Dunkel L
Citation:
JCI Insight. 2020;[Epub ahead of print] doi:10.1172/jci.insight.133434
Abstract:
The initiation of puberty is driven by an upsurge in hypothalamic gonadotropin-releasing hormone (GnRH) secretion. In turn,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mancini A, Howard SR, Marelli F, Cabrera CP, Barnes MR, Sternberg MJE, Leprovots M, Hadjidemetriou I, Monti E, David A, Wehkalampi K, Oleari R, Lettieri A, Vezzoli V, Vassart G, Cariboni A, Bonomi M, Garcia MI, Guasti L, Dunkel L. LGR4 deficiency results in delayed puberty through impaired Wnt/β-catenin signaling. JCI Insight. 2020;[Epub ahead of print] doi:10.1172/jci.insight.133434.

Knockdown of hspg2 is associated with mandibular jaw joint fusion and neural crest cell dysfunction in zebrafish

Authors:
Castellanos BS, Quintana A
Citation:
Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-27670/v1
Abstract:
Background: Heparan sulfate proteoglycan 2 (HSPG2) encodes for perlecan, a large proteoglycan that plays an important role in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Castellanos BS, Quintana A. Knockdown of hspg2 is associated with mandibular jaw joint fusion and neural crest cell dysfunction in zebrafish. Research Square. 2020;[preprint] doi:10.21203/rs.3.rs-27670/v1.

Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle

Authors:
Chestnut B, Casie Chetty S, Koenig AL, Sumanas S
Citation:
Nat Commun. 2020;11:2796. doi:10.1038/s41467-020-16515-y
Abstract:
Cell fate decisions involved in vascular and hematopoietic embryonic development are still poorly understood. An ETS...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chestnut B, Casie Chetty S, Koenig AL, Sumanas S. Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle. Nat Commun. 2020;11:2796. doi:10.1038/s41467-020-16515-y.

Extra-hypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance

Authors:
Duque-Wilckens N, Torres L, Yokoyama S, Minie V, Tran A, Petkova S, Hao R, Ramos-Maciel S, Rioa R, Jackson K, Flores-Ramirez F, Garcia-Carachure I, Pesavento PA, Iniguez S, Grinevich V, Trainor BC
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.06.02.129981
Abstract:
Oxytocin increases the salience of both positive and negative social contexts and it is thought that these diverse actions on...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Duque-Wilckens N, Torres L, Yokoyama S, Minie V, Tran A, Petkova S, Hao R, Ramos-Maciel S, Rioa R, Jackson K, Flores-Ramirez F, Garcia-Carachure I, Pesavento PA, Iniguez S, Grinevich V, Trainor BC. Extra-hypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance. bioRxiv. 2020;[preprint] doi:10.1101/2020.06.02.129981 .

Trim45 is essential to the development of the diencephalon and eye in zebrafish embryos

Authors:
Choe S, Huh TL, Rhee M
Citation:
Anim Cells Syst (Seoul). 2020 Apr 22;24(2):99-106. doi: 10.1080/19768354.2020.1751281
Abstract:
Trim45 is one of the RING (really interesting new gene) finger containing E3 ligase, which belongs to TRIM (Tripartite motif)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Choe S, Huh TL, Rhee M. Trim45 is essential to the development of the diencephalon and eye in zebrafish embryos. Anim Cells Syst (Seoul). 2020 Apr 22;24(2):99-106. doi: 10.1080/19768354.2020.1751281.

CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia

Authors:
Robinson AM, Takahashi S, Brotslaw EJ, Ahmad A, Ferrer E, Procissi D, Richter CP, Cheatham MA, Mitchell BJ, Zheng J
Citation:
Proc Natl Acad Sci U S A. 2020 Jun 1:201907335. doi: 10.1073/pnas.1907335117. Online ahead of print
Abstract:
Synchronized beating of cilia on multiciliated cells (MCCs) generates a directional flow of mucus across epithelia. This...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Robinson AM, Takahashi S, Brotslaw EJ, Ahmad A, Ferrer E, Procissi D, Richter CP, Cheatham MA, Mitchell BJ, Zheng J. CAMSAP3 facilitates basal body polarity and the formation of the central pair of microtubules in motile cilia. Proc Natl Acad Sci U S A. 2020 Jun 1:201907335. doi: 10.1073/pnas.1907335117. Online ahead of print.

Lmo7a Coordinates Neural Crest Migration and Lineage Specification by Regulating Cell Adhesion Dynamics

Authors:
Tatarakis DM, Tuttle A, Schilling TF
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.30.125468
Abstract:
Cell migration requires dynamic regulation of cell-cell signaling and cell adhesion. Neural crest (NC) cells are highly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tatarakis DM, Tuttle A, Schilling TF. Lmo7a Coordinates Neural Crest Migration and Lineage Specification by Regulating Cell Adhesion Dynamics. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.30.125468 .

Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

Authors:
Veerapathiran S, Teh C, Zhu S, Kartigayen I, Korzh V, Matsudaira PT, Wohland T
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.29.124560
Abstract:
Wnt3 proteins are lipidated and glycosylated, secreted signaling molecules that play an im-portant role in zebrafish neural...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Veerapathiran S, Teh C, Zhu S, Kartigayen I, Korzh V, Matsudaira PT, Wohland T. Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.29.124560.

Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom

Authors:
Sachkova MY, Landau M, Surm JM, Macrander J, Singer S, Reitzel AM, Moran Y
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.28.121442
Abstract:
The sea anemone Nematostella vectensis (Anthozoa, Cnidaria) is a powerful model system for characterizing the evolution of...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cniderian)
Citation Extract:
Sachkova MY, Landau M, Surm JM, Macrander J, Singer S, Reitzel AM, Moran Y. Toxin-like neuropeptides in the sea anemone Nematostella unravel recruitment from the nervous system to venom. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.28.121442 .

Viral-Induced Alternative Splicing of Host Genes Promotes Influenza Replication

Authors:
Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BMA, Cherry S, Lynch KW
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.28.122044
Abstract:
Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here we show that infection...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: A549
Citation Extract:
Thompson MG, Dittmar M, Mallory MJ, Bhat P, Ferretti MB, Fontoura BMA, Cherry S, Lynch KW. Viral-Induced Alternative Splicing of Host Genes Promotes Influenza Replication. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.28.122044.

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