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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11399 scientific papers returned from the database with the search filters currently being used below.

The Core Splicing Factors EFTUD2, SNRPB and TXNL4A Are Essential for Neural Crest and Craniofacial Development

Authors:
Park BY, Tachi-Duprat M, Ihewulezi C, Devotta A, Saint-Jeannet JP
Citation:
J Dev Biol. 2022 Jul 8;10(3):29. doi: 10.3390/jdb10030029
Epub:
Not Epub
Abstract:
Mandibulofacial dysostosis (MFD) is a human congenital disorder characterized by hypoplastic neural-crest-derived craniofacial...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Park BY, Tachi-Duprat M, Ihewulezi C, Devotta A, Saint-Jeannet JP. The Core Splicing Factors EFTUD2, SNRPB and TXNL4A Are Essential for Neural Crest and Craniofacial Development. J Dev Biol. 2022 Jul 8;10(3):29. doi: 10.3390/jdb10030029.

CRMP2 and CRMP4 are required for the formation of commissural tracts in the developing zebrafish forebrain

Authors:
Guo Y, Oliveros CF, Ohshima T
Citation:
Dev Neurobiol. 2022 Aug 5. doi: 10.1002/dneu.22897. Online ahead of print
Epub:
Yes
Abstract:
Axonal connections between the two sides of the brain are essential for processing sensorimotor functions, especially in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guo Y, Oliveros CF, Ohshima T. CRMP2 and CRMP4 are required for the formation of commissural tracts in the developing zebrafish forebrain. Dev Neurobiol. 2022 Aug 5. doi: 10.1002/dneu.22897. Online ahead of print.

Kynurenine-3-monooxygenase expression is activated in the pancreatic endocrine cells by diabetes and its blockade improves glucose-stimulated insulin secretion

Authors:
Liu J, Bailbé D, Raynal S, Carbonne C, Zhen D, Dairou J, Gausseres B, Armanet M, Domet T, Pitasi CL, Movassat J, Lim CK, Guillemin GJ, Autier V, Kergoat M, Portha B
Citation:
Biochim Biophys Acta Mol Basis Dis. 2022 Jul 29:166509. doi: 10.1016/j.bbadis.2022.166509. Online ahead of print
Epub:
Not Epub
Abstract:
Type 2 diabetes is associated with an inflammatory phenotype in the pancreatic islets. We previously demonstrated that...
Organism or Cell Type:
organ culture: rat GK islets
Citation Extract:
Liu J, Bailbé D, Raynal S, Carbonne C, Zhen D, Dairou J, Gausseres B, Armanet M, Domet T, Pitasi CL, Movassat J, Lim CK, Guillemin GJ, Autier V, Kergoat M, Portha B. Kynurenine-3-monooxygenase expression is activated in the pancreatic endocrine cells by diabetes and its blockade improves glucose-stimulated insulin secretion. Biochim Biophys Acta Mol Basis Dis. 2022 Jul 29:166509. doi: 10.1016/j.bbadis.2022.166509. Online ahead of print.

Ifi30 Is Required for Sprouting Angiogenesis During Caudal Vein Plexus Formation in Zebrafish

Authors:
Wang X, Ge X, Qin Y, Liu D, Chen C
Citation:
Front Physiol. 2022 Jul 13;13:919579. doi: 10.3389/fphys.2022.919579. eCollection 2022
Epub:
Not Epub
Abstract:
Interferon-gamma-inducible protein 30 (IFI30) is a critical enzyme that mainly exists in immune cells and functions in reducing...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang X, Ge X, Qin Y, Liu D, Chen C. Ifi30 Is Required for Sprouting Angiogenesis During Caudal Vein Plexus Formation in Zebrafish. Front Physiol. 2022 Jul 13;13:919579. doi: 10.3389/fphys.2022.919579. eCollection 2022.

Estrogens revert neutrophil hyperplasia by inhibiting Hif1α-cMyb pathway in zebrafish myelodysplastic syndromes models

Authors:
Li X, Wang L, Qin X, Chen X, Li L, Huang Z, Zhang W, Liu W
Citation:
Cell Death Discov. 2022 Jul 16;8(1):323. doi: 10.1038/s41420-022-01121-2
Epub:
Not Epub
Abstract:
Myelodysplastic syndromes (MDS) are characterized by daunting genetic heterogeneity and a high risk of leukemic transformation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, Wang L, Qin X, Chen X, Li L, Huang Z, Zhang W, Liu W. Estrogens revert neutrophil hyperplasia by inhibiting Hif1α-cMyb pathway in zebrafish myelodysplastic syndromes models. Cell Death Discov. 2022 Jul 16;8(1):323. doi: 10.1038/s41420-022-01121-2.

Thiosulfate sulfurtransferase prevents hyperglycemic damage to the zebrafish pronephros in an experimental model for diabetes

Authors:
Al-Dahmani ZM, Li X, Wiggenhauser LM, Ott H, Kruithof PD, Lunev S, A Batista F, Luo Y, Dolga AM, Morton NM, Groves MR, Kroll J, van Goor H
Citation:
Sci Rep. 2022 Jul 15;12(1):12077. doi: 10.1038/s41598-022-16320-1
Epub:
Not Epub
Abstract:
Thiosulfate sulfurtransferase (TST, EC 2.8.1.1), also known as Rhodanese, was initially discovered as a cyanide detoxification...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Al-Dahmani ZM, Li X, Wiggenhauser LM, Ott H, Kruithof PD, Lunev S, A Batista F, Luo Y, Dolga AM, Morton NM, Groves MR, Kroll J, van Goor H. Thiosulfate sulfurtransferase prevents hyperglycemic damage to the zebrafish pronephros in an experimental model for diabetes. Sci Rep. 2022 Jul 15;12(1):12077. doi: 10.1038/s41598-022-16320-1.

A non-transcriptional function of Yap regulates the DNA replication program in Xenopus laevis

Authors:
Meléndez García R, Haccard O, Chesneau A, Narassimprakash H, Roger J, Perron M, Marheineke K, Bronchain O
Citation:
Elife. 2022 Jul 15;11:e75741. doi: 10.7554/eLife.75741
Epub:
Not Epub
Abstract:
In multicellular eukaryotic organisms, the initiation of DNA replication occurs asynchronously throughout S-phase according to...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Meléndez García R, Haccard O, Chesneau A, Narassimprakash H, Roger J, Perron M, Marheineke K, Bronchain O. A non-transcriptional function of Yap regulates the DNA replication program in Xenopus laevis. Elife. 2022 Jul 15;11:e75741. doi: 10.7554/eLife.75741.

Gene expression and functional analysis of Aha1a and Aha1b in stress response in zebrafish

Authors:
Xiao H, Wang H, He Q, Zhou J, Du S
Citation:
Comp Biochem Physiol B Biochem Mol Biol. 2022 Jul 10;262:110777. doi: 10.1016/j.cbpb.2022.110777. Online ahead of print
Epub:
Not Epub
Abstract:
Activator of heat shock protein 90 (hsp90) ATPase (Aha1) is a Hsp90 co-chaperone required for Hsp90 ATPase activation. Aha1 is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xiao H, Wang H, He Q, Zhou J, Du S. Gene expression and functional analysis of Aha1a and Aha1b in stress response in zebrafish. Comp Biochem Physiol B Biochem Mol Biol. 2022 Jul 10;262:110777. doi: 10.1016/j.cbpb.2022.110777. Online ahead of print.

Neuropathy-associated Fars2 deficiency affects neuronal development and potentiates neuronal apoptosis by impairing mitochondrial function

Authors:
Chen X, Liu F, Li B, Wang Y, Yuan L, Yin A, Chen Q, Hu W, Yao Y, Zhang M, Wu Y, Chen K
Citation:
Cell Biosci. 2022 Jul 6;12(1):103. doi: 10.1186/s13578-022-00838-y
Epub:
Not Epub
Abstract:
Background: Neurodegenerative diseases encompass an extensive and heterogeneous group of nervous system disorders which are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen X, Liu F, Li B, Wang Y, Yuan L, Yin A, Chen Q, Hu W, Yao Y, Zhang M, Wu Y, Chen K. Neuropathy-associated Fars2 deficiency affects neuronal development and potentiates neuronal apoptosis by impairing mitochondrial function. Cell Biosci. 2022 Jul 6;12(1):103. doi: 10.1186/s13578-022-00838-y.

Use of vivo-morpholinos for gene knockdown in the postnatal shark retina

Authors:
Rodríguez-Arrizabalaga M, Hernández-Núñez I, Candal E, Barreiro-Iglesias A
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.07.11.499558
Epub:
Not Epub
Abstract:
Work in the catshark Scyliorhinus canicula has shown that the evolutionary origin of postnatal neurogenesis in vertebrates is...
Delivery Method:
Vivo-Morpholino intraocular injection
Organism or Cell Type:
Scyliorhinus canicula (catshark)
Citation Extract:
Rodríguez-Arrizabalaga M, Hernández-Núñez I, Candal E, Barreiro-Iglesias A. Use of vivo-morpholinos for gene knockdown in the postnatal shark retina. bioRxiv. 2022;[preprint] doi:10.1101/2022.07.11.499558 .

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