You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10930 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease

Authors:
Getwan M, Hoppmann A, Schlosser P, Grand K, Song W, Diehl R, Schroda S, Heeg F, Deutsch K, Hildebrandt F, Lausch E, Köttgen A, Lienkamp SS
Citation:
Proc Nat Acad Sci USA. 2021;118(39):e2106770118. doi:10.1073/pnas.2106770118
Epub:
Not Epub
Abstract:
Skeletal ciliopathies (e.g., Jeune syndrome, short rib polydactyly syndrome, and Sensenbrenner syndrome) are frequently...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis
Citation Extract:
Getwan M, Hoppmann A, Schlosser P, Grand K, Song W, Diehl R, Schroda S, Heeg F, Deutsch K, Hildebrandt F, Lausch E, Köttgen A, Lienkamp SS. Ttc30a affects tubulin modifications in a model for ciliary chondrodysplasia with polycystic kidney disease. Proc Nat Acad Sci USA. 2021;118(39):e2106770118. doi:10.1073/pnas.2106770118.

HMGA2 contributes to vascular development and sprouting angiogenesis by promoting IGFBP2 production

Authors:
Wang J, Chen Y, Zeng Z, Feng R, Wang Q, Zhang Q, Sun K, Chen AF, Lu Y, Yu Y
Citation:
Exp Cell Res. 2021;[Epub] doi:10.1016/j.yexcr.2021.112831
Epub:
Yes
Abstract:
Angiogenesis is the process by which new blood vessels form from preexisting vessels and regulates the processes of embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang J, Chen Y, Zeng Z, Feng R, Wang Q, Zhang Q, Sun K, Chen AF, Lu Y, Yu Y. HMGA2 contributes to vascular development and sprouting angiogenesis by promoting IGFBP2 production. Exp Cell Res. 2021;[Epub] doi:10.1016/j.yexcr.2021.112831.

Cell-cell contact landscapes in Xenopus gastrula tissues

Authors:
Barua D, Nagel M, Winklbauer R
Citation:
Proc Nat Acad Sci USA. 2021;118(39):e2107953118 [Epub] doi:10.1073/pnas.2107953118
Epub:
Yes
Abstract:
Molecular and structural facets of cell-cell adhesion have been extensively studied in monolayered epithelia. Here, we perform...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Barua D, Nagel M, Winklbauer R. Cell-cell contact landscapes in Xenopus gastrula tissues. Proc Nat Acad Sci USA. 2021;118(39):e2107953118 [Epub] doi:10.1073/pnas.2107953118.

Notch-mediated re-specification of neuronal identity during central nervous system development

Authors:
Engerer P, Petridou E, Williams PR, Suzuki SC, Yoshimatsu T, Portugues R, Misgeld T, Godinho L
Citation:
Current Biology. 2021;[Epub] doi: 10.1016/j.cub.2021.08.049
Epub:
Not Epub
Abstract:
Neuronal identity has long been thought of as immutable, so that once a cell acquires a specific fate, it is maintained for...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Engerer P, Petridou E, Williams PR, Suzuki SC, Yoshimatsu T, Portugues R, Misgeld T, Godinho L. Notch-mediated re-specification of neuronal identity during central nervous system development. Current Biology. 2021;[Epub] doi: 10.1016/j.cub.2021.08.049.

A new strategy to increase RNA Editing at the Q/R Site of GluA2 AMPA receptor subunits by targeting alternative splicing patterns of ADAR2

Authors:
Chaytow H, Hassan IS, Akbar S, Popplewell L, Dickson G, Chen PE
Citation:
J Neurosci Methods. 2021;[Epub] doi:10.1016/j.jneumeth.2021.109357
Epub:
Not Epub
Abstract:
Background: The GluA2 subunit of AMPA receptors (AMPARs) undergoes RNA editing at a specific base mediated by the enzyme ADAR2...
Organism or Cell Type:
cell culture
Citation Extract:
Chaytow H, Hassan IS, Akbar S, Popplewell L, Dickson G, Chen PE. A new strategy to increase RNA Editing at the Q/R Site of GluA2 AMPA receptor subunits by targeting alternative splicing patterns of ADAR2. J Neurosci Methods. 2021;[Epub] doi:10.1016/j.jneumeth.2021.109357.

Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5

Authors:
Maerker M, Getwan M, Dowdle ME, McSheene JC, Gonzalez V, Pelliccia JL, Hamilton DS, Yartseva V, Vejnar C, Tingler M, Minegishi K, Vick P, Giraldez AJ, Hamada H, Burdine RD, Sheets MD, Blum M, Schweickert A
Citation:
Nat Commun. 2021;12(1):5482. doi:10.1038/s41467-021-25464-z
Epub:
Not Epub
Abstract:
Rotating cilia at the vertebrate left-right organizer (LRO) generate an asymmetric leftward flow, which is sensed by cells at...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus, zebrafish
Citation Extract:
Maerker M, Getwan M, Dowdle ME, McSheene JC, Gonzalez V, Pelliccia JL, Hamilton DS, Yartseva V, Vejnar C, Tingler M, Minegishi K, Vick P, Giraldez AJ, Hamada H, Burdine RD, Sheets MD, Blum M, Schweickert A. Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5. Nat Commun. 2021;12(1):5482. doi:10.1038/s41467-021-25464-z.

Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain

Authors:
Suzzi S, Ahrendt R, Hans S, Semenova SA, Chekuru A, Wirsching P, Kroehne V, Bilican S, Sayed S, Winkler S, Spieß S, Machate A, Kaslin J, Panula P, Brand M
Citation:
PLoS Genet. 2021;17(9):e1009794. doi:10.1371/journal.pgen.1009794
Epub:
Not Epub
Abstract:
LRRK2 gain-of-function is considered a major cause of Parkinson’s disease (PD) in humans. However, pathogenicity of LRRK2 loss-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Suzzi S, Ahrendt R, Hans S, Semenova SA, Chekuru A, Wirsching P, Kroehne V, Bilican S, Sayed S, Winkler S, Spieß S, Machate A, Kaslin J, Panula P, Brand M. Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain. PLoS Genet. 2021;17(9):e1009794. doi:10.1371/journal.pgen.1009794.

CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression

Authors:
Franke M, De la Calle-Mustienes E, Neto A, Almuedo-Castillo M, Irastorza-Azcarate I, Acemel RD, Tena JJ, Santos-Pereira JM, Gómez-Skarmeta JL
Citation:
Nat Commun. 2021 Sep 13;12(1):5415. doi: 10.1038/s41467-021-25604-5
Epub:
Not Epub
Abstract:
Coordinated chromatin interactions between enhancers and promoters are critical for gene regulation. The architectural protein...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Franke M, De la Calle-Mustienes E, Neto A, Almuedo-Castillo M, Irastorza-Azcarate I, Acemel RD, Tena JJ, Santos-Pereira JM, Gómez-Skarmeta JL. CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression. Nat Commun. 2021 Sep 13;12(1):5415. doi: 10.1038/s41467-021-25604-5.

Development and biological characterization of a clinical gene transfer vector for the treatment of MAK-associated retinitis pigmentosa

Authors:
Tucker BA, Burnight ER, Cranston CM, Ulferts MJ, Luse MA, Westfall T, Scott CA, Marsden A, Gibson-Corley K, Wiley LA, Han IC, Slusarski DC, Mullins RF, Stone EM
Citation:
Gene Ther. 2021 Sep 14. doi: 10.1038/s41434-021-00291-5. Online ahead of print
Epub:
Yes
Abstract:
By combining next generation whole exome sequencing and induced pluripotent stem cell (iPSC) technology we found that an Alu...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tucker BA, Burnight ER, Cranston CM, Ulferts MJ, Luse MA, Westfall T, Scott CA, Marsden A, Gibson-Corley K, Wiley LA, Han IC, Slusarski DC, Mullins RF, Stone EM. Development and biological characterization of a clinical gene transfer vector for the treatment of MAK-associated retinitis pigmentosa. Gene Ther. 2021 Sep 14. doi: 10.1038/s41434-021-00291-5. Online ahead of print.

N-myc Downstream Regulated Gene 1 (NDRG1) functions as a molecular switch for cellular adaptation to hypoxia

Authors:
Park JS, Gabel AM, Kang L, Canales B, Kassir P, Osei-Ntansah A, Tran ND, Viswanathan S, Lee Y-S, Brewster R
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.09.10.459675
Epub:
Not Epub
Abstract:
Lack of oxygen (hypoxia and anoxia) is detrimental to cell function and survival and underlies many disease conditions. Hence,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Park JS, Gabel AM, Kang L, Canales B, Kassir P, Osei-Ntansah A, Tran ND, Viswanathan S, Lee Y-S, Brewster R. N-myc Downstream Regulated Gene 1 (NDRG1) functions as a molecular switch for cellular adaptation to hypoxia. bioRxiv. 2021;[preprint] doi:10.1101/2021.09.10.459675.

Pages