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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12402 scientific papers returned from the database with the search filters currently being used below.
There are 12402 scientific papers returned from the database with the search filters currently being used below.
cGAS-STING are responsible for premature aging of telomerase-deficient zebrafish
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Citation:
EMBO J. 2025 Jun 9. doi: 10.1038/s44318-025-00482-5. Epub ahead of print. PMID: 40490553 Epub:
Not Epub Abstract:
Telomere shortening occurs in multiple tissues throughout aging. When telomeres become critically short, they trigger DNA-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Şerifoğlu N, Allavena G, Lopes-Bastos B, Marzullo M, Marques A, Colibert P, Bousounis P, Trompouki E, Ferreira MG. cGAS-STING are responsible for premature aging of telomerase-deficient zebrafish. EMBO J. 2025 Jun 9. doi: 10.1038/s44318-025-00482-5. Epub ahead of print. PMID: 40490553. |
BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD
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Citation:
bioRxiv [Preprint]. 2025 Mar 10:2024.08.27.608867. doi: 10.1101/2024.08.27.608867. PMID: 39253489; PMCID: PMC11383298 Epub:
Not Epub Abstract:
Autosomal dominant polycystic kidney disease (ADPKD) is primarily of adult-onset and caused by pathogenic variants in PKD1 or... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Tran U, Streets AJ, Smith D, Decker E, Kirschfink A, Izem L, Hassey JM, Rutland B, Valluru MK, Bräsen JH, Ott E, Epting D, Eisenberger T, Ong AC, Bergmann C, Wessely O. BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD. bioRxiv [Preprint]. 2025 Mar 10:2024.08.27.608867. doi: 10.1101/2024.08.27.608867. PMID: 39253489; PMCID: PMC11383298. |
A Cell Type-Specific Role for Tubb6 in Ciliogenesis of Xenopus Epidermal Multiciliated Cells
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Citation:
bioRxiv [preprint] 2025.05.31.657203; doi: https://doi.org/10.1101/2025.05.31.657203 Epub:
Not Epub Abstract:
Cilia are microtubule-based organelles found on the surface of most eukaryotic cells. These microtubules are composed of α- and... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Xu X, Ross J, Clark F, Wei S, Sun J. A Cell Type-Specific Role for Tubb6 in Ciliogenesis of Xenopus Epidermal Multiciliated Cells. bioRxiv [preprint] 2025.05.31.657203; doi: https://doi.org/10.1101/2025.05.31.657203. |
The Potential Role of Gonadotropic Hormones and Their Receptors in Sex Differentiation of Nile Tilapia, Oreochromis niloticus
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Citation:
International Journal of Molecular Sciences. 2025; 26(11):5376. https://doi.org/10.3390/ijms26115376 Epub:
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Nile tilapia, as an ideal model for studying sex differentiation, is a popular farmed fish worldwide with a stable XX/XY sex-... Delivery Method:
microinjection Organism or Cell Type:
Nile tilapia Citation Extract: Gao H, Yan H, Arai T, Aranyakanont C, Li S, Ijiri S. The Potential Role of Gonadotropic Hormones and Their Receptors in Sex Differentiation of Nile Tilapia, Oreochromis niloticus. International Journal of Molecular Sciences. 2025; 26(11):5376. https://doi.org/10.3390/ijms26115376. |
Plakophilin 3 Is Involved in Basal Body Docking in Multiciliated Cells
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Citation:
International Journal of Molecular Sciences. 2025; 26(11):5381. https://doi.org/10.3390/ijms26115381 Epub:
Not Epub Abstract:
Multiciliated cells generate fluid flow along epithelial surfaces, and defects in their development or function cause primary... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Louka P, Kyriakou C, Diakourti I, Skourides P. Plakophilin 3 Is Involved in Basal Body Docking in Multiciliated Cells. International Journal of Molecular Sciences. 2025; 26(11):5381. https://doi.org/10.3390/ijms26115381. |
Dis3l2 is essential for neural crest survival by modulating Akt signaling
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Citation:
Cell Commun Signal 23, 277 (2025). https://doi.org/10.1186/s12964-025-02288-8 Epub:
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DIS3-like 3’-5’ exoribonuclease 2 (DIS3L2), an exoribonuclease, is known to preferentially degrade uridylated RNA substrates,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: D’Silva S, Prasad T, Kumar M. . Dis3l2 is essential for neural crest survival by modulating Akt signaling. Cell Commun Signal 23, 277 (2025). https://doi.org/10.1186/s12964-025-02288-8. |
Mutation of beta-tubulin 4B gene (TUBB4B) causes autosomal dominant retinitis pigmentosa with sensorineural hearing loss in a multigenerational family
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Citation:
Molecular Vision 2025; 31:175-188. Published 16 May 2025 Epub:
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Purpose: Members of a multigenerational Canadian family presented to an inherited retinal degeneration (IRD) clinic with... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gregory-Evans CY, Joe AW, Gregory-Evans K. Mutation of beta-tubulin 4B gene (TUBB4B) causes autosomal dominant retinitis pigmentosa with sensorineural hearing loss in a multigenerational family. Molecular Vision 2025; 31:175-188. Published 16 May 2025. |
TTC21B variants disrupt the left-right asymmetry and pronephric development in zebrafish
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Citation:
Genes & Diseases, 2025, 101709, ISSN 2352-3042, https://doi.org/10.1016/j.gendis.2025.101709 Epub:
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Nephronophthisis (NPHP) is an autosomal recessive kidney disease and is the most prevalent monogenic cause of end-stage renal... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Deng L, Yang Y, Yin X, Yang J, Duan Y, Wang K, Duan W, Zhang Y, Xiong B, Zhou J. TTC21B variants disrupt the left-right asymmetry and pronephric development in zebrafish. Genes & Diseases, 2025, 101709, ISSN 2352-3042, https://doi.org/10.1016/j.gendis.2025.101709. |
Zebrafish sall1a and sall4 contribute to body elongation
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Citation:
Dev Biol. 2025 Jun 5:S0012-1606(25)00165-4. doi: 10.1016/j.ydbio.2025.06.006. Epub ahead of print. PMID: 40482694 Epub:
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Vertebrate embryos elongate the body after gastrulation. Unlike in mice, which elongate both the trunk and tail after... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kawakami H, Bailey A, Gavin E, Gearhart MD, Isabella AJ, Kawakami Y. Kawakami H, Bailey A, Gavin E, Gearhart MD, Isabella AJ, Kawakami Y. Zebrafish sall1a and sall4 contribute to body elongation. Dev Biol. 2025 Jun 5:S0012-1606(25)00165-4. doi: 10.1016/j.ydbio.2025.06.006. Epub ahead of print. PMID: 40482694. |
Translation suppresses exogenous target RNA-mediated microRNA decay
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Citation:
Nat Commun. 2025 Jun 6;16(1):5257. doi: 10.1038/s41467-025-60374-4. PMID: 40480978; PMCID: PMC12144122 Epub:
Not Epub Abstract:
MicroRNAs (miRNAs) interact with the target mRNAs to induce translational repression and mRNA degradation. Interestingly,... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
cell culture: HEK293T and mouse striatal cell model of Huntington's Disease Citation Extract: Li T, Li L, Hiers NM, Sheng P, Wang Y, Traugot CM, Effinger-Morris JF, Akaphan P, Liu Y, Bian J, Fujii K, Xie M. Translation suppresses exogenous target RNA-mediated microRNA decay. Nat Commun. 2025 Jun 6;16(1):5257. doi: 10.1038/s41467-025-60374-4. PMID: 40480978; PMCID: PMC12144122. |