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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10704 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Rab35 regulates skeletogenesis and gastrulation by facilitating actin remodeling and vesicular trafficking

Authors:
Remsburg C, Testa M, Song JL
Citation:
Cells Dev. 2021 Mar;165:203660. doi:10.1016/j.cdev.2021.203660. Epub 2021 Feb 8
Abstract:
Rab35 is a small GTPase that regulates plasma membrane to early endosome vesicular trafficking and mediates actin remodeling to...
Delivery Method:
microinjection
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Remsburg C, Testa M, Song JL. Rab35 regulates skeletogenesis and gastrulation by facilitating actin remodeling and vesicular trafficking. Cells Dev. 2021 Mar;165:203660. doi:10.1016/j.cdev.2021.203660. Epub 2021 Feb 8.

Novel pre-clinical model for CDKL5 Deficiency Disorder

Authors:
Serrano RJ, Lee C, Bryson-Richardson RJ, Sztal TE
Citation:
bioRxiv. 2021;[preprint] doi: https://doi.org/10.1101/2021.04.07.438335
Abstract:
Cyclin-dependent kinase-like-5 (CDKL5) Deficiency Disorder (CDD) is a severe X-linked neurodegenerative disease characterized...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Serrano RJ, Lee C, Bryson-Richardson RJ, Sztal TE. Novel pre-clinical model for CDKL5 Deficiency Disorder. bioRxiv. 2021;[preprint] doi: https://doi.org/10.1101/2021.04.07.438335.

Exploring zebrafish larvae as a COVID-19 model: probable SARS-COV-2 replication in the swim bladder

Authors:
Laghi V, Rezelj V, Boucontet L, Boudinot P, Salinas I, Lutfalla G, Vignuzzi M, Levraud J-P
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.08.439059
Abstract:
Animal models are essential to understand COVID-19 pathophysiology and for pre-clinical assessment of drugs and other...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Laghi V, Rezelj V, Boucontet L, Boudinot P, Salinas I, Lutfalla G, Vignuzzi M, Levraud J-P. Exploring zebrafish larvae as a COVID-19 model: probable SARS-COV-2 replication in the swim bladder. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.08.439059.

Hemodynamic Forces Regulate Cardiac Regeneration-Responsive Enhancer Activity during Ventricle Regeneration

Authors:
Geng F, Ma J, Li X, Hu Z, Zhang R
Citation:
Int J Mol Sci. 2021;22(8):3945. doi:10.3390/ijms22083945
Abstract:
Cardiac regenerative capacity varies widely among vertebrates. Zebrafish can robustly regenerate injured hearts and are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Geng F, Ma J, Li X, Hu Z, Zhang R. Hemodynamic Forces Regulate Cardiac Regeneration-Responsive Enhancer Activity during Ventricle Regeneration. Int J Mol Sci. 2021;22(8):3945. doi:10.3390/ijms22083945.

Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models

Authors:
Siegerist F, Lange T, Iervolino A, Koppe TM, Zhou W, Capasso G, Endlich K, Endlich N
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.09.439067
Abstract:
The majority of kidney diseases arise from the loss of podocytes and from morphological changes of their highly complex foot...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Siegerist F, Lange T, Iervolino A, Koppe TM, Zhou W, Capasso G, Endlich K, Endlich N. Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.09.439067 .

Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis

Authors:
Adar-Levor S, Nachmias D, Gal-Oz ST, Jahn YM, Peyrieras N, Zaritsky A, Birnbaum RY, Elia N
Citation:
Proc Nat Acad Sci USA. 2021;118(15):e2021210118. doi:10.1073/pnas.2021210118
Abstract:
Animal cytokinesis ends with the formation of a thin intercellular membrane bridge that connects the two newly formed sibling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Adar-Levor S, Nachmias D, Gal-Oz ST, Jahn YM, Peyrieras N, Zaritsky A, Birnbaum RY, Elia N. Cytokinetic abscission is part of the midblastula transition in early zebrafish embryogenesis. Proc Nat Acad Sci USA. 2021;118(15):e2021210118. doi:10.1073/pnas.2021210118.

Zebrafish modeling mimics developmental phenotype of patients with RAPGEF1 mutation

Authors:
Li N, Zhou P, Yang M, Fang X, Krämer N, Mughal TA, Abbasi AA, Yang Y, Kaindl AM, Hu H
Citation:
Clin Genet. 2021 Apr 9. doi: 10.1111/cge.13965. Online ahead of print
Abstract:
RAPGEF1 is a guanine nucleotide exchange factor responsible for transmitting extracellular signals to the Ras family of GTPase...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li N, Zhou P, Yang M, Fang X, Krämer N, Mughal TA, Abbasi AA, Yang Y, Kaindl AM, Hu H. Zebrafish modeling mimics developmental phenotype of patients with RAPGEF1 mutation. Clin Genet. 2021 Apr 9. doi: 10.1111/cge.13965. Online ahead of print.

Endothelial struts enable the generation of large lumenized blood vessels de novo

Authors:
Weijts B, Shaked I, Ginsberg M, Kleinfeld D, Robin C, Traver D
Citation:
Nat Cell Biol. 2021;23(4):322-329. doi:10.1038/s41556-021-00664-3
Abstract:
De novo blood vessel formation occurs through coalescence of endothelial cells (ECs) into a cord-like structure, followed by...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Weijts B, Shaked I, Ginsberg M, Kleinfeld D, Robin C, Traver D. Endothelial struts enable the generation of large lumenized blood vessels de novo. Nat Cell Biol. 2021;23(4):322-329. doi:10.1038/s41556-021-00664-3.

BMP heterodimers signal via distinct type I receptor class functions

Authors:
Tajer B, Dutko JA, Little SC, Mullins MC
Citation:
Proc Nat Acad Sci USA. 2021;118(15):e2017952118. doi:10.1073/pnas.2017952118
Abstract:
Heterodimeric TGF-β ligands outperform homodimers in a variety of developmental, cell culture, and therapeutic contexts;...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tajer B, Dutko JA, Little SC, Mullins MC. BMP heterodimers signal via distinct type I receptor class functions. Proc Nat Acad Sci USA. 2021;118(15):e2017952118. doi:10.1073/pnas.2017952118.

Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction

Authors:
Peruzzo R, Corrà S, Costa R, Brischigliaro M, Varanita T, Biasutto L, Rampazzo C, Ghezzi D, Leanza L, Zoratti M, Zeviani M, De Pittà C, Viscomi C, Costa R, Szabò I
Citation:
Nat Comm. 2021;12(1):2103. doi:10.1038/s41467-021-22062-x
Abstract:
Mitochondrial diseases impair oxidative phosphorylation and ATP production, while effective treatment is still lacking....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peruzzo R, Corrà S, Costa R, Brischigliaro M, Varanita T, Biasutto L, Rampazzo C, Ghezzi D, Leanza L, Zoratti M, Zeviani M, De Pittà C, Viscomi C, Costa R, Szabò I. Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction. Nat Comm. 2021;12(1):2103. doi:10.1038/s41467-021-22062-x.

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