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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12299 scientific papers returned from the database with the search filters currently being used below.

Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427

Authors:
Kostiuk V, Kabir R, Levangie K, Empke S, Morgan K, Owens NDL, Lusk CP, Khokha MK
Citation:
Development. 2025 Jan 15;152(2):dev202865. doi: 10.1242/dev.202865. Epub 2025 Feb 4. PMID: 39791357
Epub:
Not Epub
Abstract:
Emerging evidence suggests that the nuclear pore complex can have unique compositions and distinct nucleoporin functions in...
Delivery Method:
microinjection
Organism or Cell Type:
X. tropicalis
Citation Extract:
Kostiuk V, Kabir R, Levangie K, Empke S, Morgan K, Owens NDL, Lusk CP, Khokha MK. Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427. Development. 2025 Jan 15;152(2):dev202865. doi: 10.1242/dev.202865. Epub 2025 Feb 4. PMID: 39791357.

ROS regulates circadian rhythms by modulating Ezh2 interactions with clock proteins

Authors:
Zhang H-Y, Li K-Y, YWang Y-L, Wei C-J, Gao Y-X, Zhou R, Zhong Y-B, Yin Z-J, Ren D-L
Citation:
Redox Biology. 2025. 103526, ISSN 2213-2317, https://doi.org/10.1016/j.redox.2025.103526
Epub:
Not Epub
Abstract:
Abstract: Redox imbalance induced by the accumulation of reactive oxygen species (ROS) accelerates age-related processes, often...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang H-Y, Li K-Y, YWang Y-L, Wei C-J, Gao Y-X, Zhou R, Zhong Y-B, Yin Z-J, Ren D-L. ROS regulates circadian rhythms by modulating Ezh2 interactions with clock proteins. Redox Biology. 2025. 103526, ISSN 2213-2317, https://doi.org/10.1016/j.redox.2025.103526.

Solid Phase Synthesis of Casimersen and Its 3ʹ-end Modification for Therapeutic Benefits

Authors:
Sinha S, Das A, Pratihar S, Nath Sharma S, Kundu J
Citation:
ChemRxiv [preprint]. 2025; doi:10.26434/chemrxiv-2025-mf99n
Epub:
Not Epub
Abstract:
Phosphorodiamidate Morpholino Oligonucleotides (PMO) have been well established in the treatment of muscular dystrophies with...
Delivery Method:
None
Organism or Cell Type:
None
Citation Extract:
Sinha S, Das A, Pratihar S, Nath Sharma S, Kundu J. Solid Phase Synthesis of Casimersen and Its 3ʹ-end Modification for Therapeutic Benefits. ChemRxiv [preprint]. 2025; doi:10.26434/chemrxiv-2025-mf99n.

Yellow catfish (Pelteobagrus fulvidraco) lacking of germ cells exhibited gonadal sexual dimorphism

Authors:
Ye H, Hou Y, Huang L, Yue H, Qu Z, Ruan R, Li C
Citation:
Aquaculture. Online 28 January 2025
Epub:
Not Epub
Abstract:
Yellow catfish (Pelteobagrus fulvidraco) is a valuable freshwater aquaculture species in China, characterized by an XX/XY sex...
Delivery Method:
microinjection
Organism or Cell Type:
catfish
Citation Extract:
Ye H, Hou Y, Huang L, Yue H, Qu Z, Ruan R, Li C. Yellow catfish (Pelteobagrus fulvidraco) lacking of germ cells exhibited gonadal sexual dimorphism. Aquaculture. Online 28 January 2025.

Combined loss of glyoxalase 1 and aldehyde dehydrogenase 3a1 amplifies dicarbonyl stress, impairs proteasome activity resulting in hyperglycemia and activated retinal angiogenesis

Authors:
Li S, Li H, Bennewitz K, Poschet G, Buettner M, Hausser I, Szendroedi J, Nawroth PP, Kroll J
Citation:
Metabolism. 2025 Jan 30:156149. doi: 10.1016/j.metabol.2025.156149. Epub ahead of print. PMID: 39892865
Epub:
Not Epub
Abstract:
Background & aims: Any energy consumption results in the generation of highly reactive dicarbonyls and the need to prevent...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li S, Li H, Bennewitz K, Poschet G, Buettner M, Hausser I, Szendroedi J, Nawroth PP, Kroll J. Combined loss of glyoxalase 1 and aldehyde dehydrogenase 3a1 amplifies dicarbonyl stress, impairs proteasome activity resulting in hyperglycemia and activated retinal angiogenesis. Metabolism. 2025 Jan 30:156149. doi: 10.1016/j.metabol.2025.156149. Epub ahead of print. PMID: 39892865.

Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos

Authors:
Li X, Xiong G, Luo M, Mao S, Zhang R, Meng Z, Li J, Liao X
Citation:
PLoS One. 2025 Jan 31;20(1):e0315714. doi: 10.1371/journal.pone.0315714. PMID: 39888929; PMCID: PMC11785313
Epub:
Not Epub
Abstract:
Peptidoglycan recognition proteins (PGRPs) are the evolutionarily highly conserved class of pattern recognition receptors,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, Xiong G, Luo M, Mao S, Zhang R, Meng Z, Li J, Liao X. Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos. PLoS One. 2025 Jan 31;20(1):e0315714. doi: 10.1371/journal.pone.0315714. PMID: 39888929; PMCID: PMC11785313.

Monocyte-Derived cxcl12 Guides a Directional Migration of Blood Vessels in Zebra Fish

Authors:
Lu X, Wang X, Li B, Wang X, Duan X, Liu D
Citation:
Arterioscler Thromb Vasc Biol. 2025 Jan 23. doi: 10.1161/ATVBAHA.124.321588. Epub ahead of print. PMID: 39846165
Epub:
Not Epub
Abstract:
Background: Sprouting blood vessels, reaching the aimed location, and establishing the proper connections are vital for...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu X, Wang X, Li B, Wang X, Duan X, Liu D. Monocyte-Derived cxcl12 Guides a Directional Migration of Blood Vessels in Zebra Fish. Arterioscler Thromb Vasc Biol. 2025 Jan 23. doi: 10.1161/ATVBAHA.124.321588. Epub ahead of print. PMID: 39846165.

Knockdown of zebrafish tmem242 enhances the production of ROS that signals to increase f9a expression resulting in DIC-like condition

Authors:
Deebani A, Mary J, Dhinoja S, Al Qaryoute A, Fallatah W, Jagadeeswaran P
Citation:
Sci Rep. 2025 Jan 24;15(1):3058. doi: 10.1038/s41598-025-87117-1. PMID: 39856164; PMCID: PMC11761473
Epub:
Not Epub
Abstract:
Transmembrane proteins (TMEMs) are embedded in cell membranes and often have poorly understood functions. Our RNAseq analysis...
Delivery Method:
Vivo-Morpholino piggyback hybrid; intravenous (i.v.)
Organism or Cell Type:
zebrafish
Citation Extract:
Deebani A, Mary J, Dhinoja S, Al Qaryoute A, Fallatah W, Jagadeeswaran P. Knockdown of zebrafish tmem242 enhances the production of ROS that signals to increase f9a expression resulting in DIC-like condition. Sci Rep. 2025 Jan 24;15(1):3058. doi: 10.1038/s41598-025-87117-1. PMID: 39856164; PMCID: PMC11761473.

Supracellular contractility in Xenopus laevis embryonic epithelia regulated by extracellular nucleotides and the purinergic G-protein coupled receptor P2Y2

Authors:
Joshi SD, Jackson TR, Zhang L, Stuckenholz C, Davidson LA
Citation:
bioRxiv [preprint] 2025.01.21.634176; doi: https://doi.org/10.1101/2025.01.21.634176
Epub:
Not Epub
Abstract:
Extracellular signals regulate epithelial homeostasis, cell fate and pattern cell behaviors during embryogenesis, wound healing...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Joshi SD, Jackson TR, Zhang L, Stuckenholz C, Davidson LA. Supracellular contractility in Xenopus laevis embryonic epithelia regulated by extracellular nucleotides and the purinergic G-protein coupled receptor P2Y2. bioRxiv [preprint] 2025.01.21.634176; doi: https://doi.org/10.1101/2025.01.21.634176.

PRMT1-methylated MSX1 phase separates to control palate development

Authors:
Meng L, Jiang Y, You J, Chen Y, Guo S, Chen L, Ma J
Citation:
Nat Commun. 2025 Jan 22;16(1):949. doi: 10.1038/s41467-025-56327-6. PMID: 39843447; PMCID: PMC11754605
Epub:
Not Epub
Abstract:
Little is known about the regulation and function of phase separation in craniofacial developmental disorders. MSX1 mutations...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Meng L, Jiang Y, You J, Chen Y, Guo S, Chen L, Ma J. PRMT1-methylated MSX1 phase separates to control palate development. Nat Commun. 2025 Jan 22;16(1):949. doi: 10.1038/s41467-025-56327-6. PMID: 39843447; PMCID: PMC11754605.

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