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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9876 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endodermal gene regulatory network

Authors:
Mukherjee S, Chaturvedi P, Rankin SA, Fish MB, Wizla M, Paraiso KD, MacDonald M, Chen X, Weirauch MT, Blitz IL, Cho KWY, Zorn AM
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.19.956565
Abstract:
Lineage specification depends on the integration of lineage-determining transcription factors (TFs) and signaling effectors on...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis, Xenopus tropicalis
Citation Extract:
Mukherjee S, Chaturvedi P, Rankin SA, Fish MB, Wizla M, Paraiso KD, MacDonald M, Chen X, Weirauch MT, Blitz IL, Cho KWY, Zorn AM. Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endodermal gene regulatory network. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.19.956565 .

Oocyte competence is maintained by m6A methyltransferase KIAA1429-mediated RNA metabolism during mouse follicular development

Authors:
Hu Y, Ouyang Z, Sui X, Qi M, Li M, He Y, Cao Y, Cao Q, Lu Q, Zhou S, Liu L, Liu L, Shen B, Shu W, Huo R
Citation:
Cell Death Differ. 2020;[Epub] doi:10.1038/s41418-020-0516-1
Abstract:
KIAA1429 (also known as vir-like m6A methyltransferase-associated protein (VIRMA)), a newly identified component of the RNA m6A...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Hu Y, Ouyang Z, Sui X, Qi M, Li M, He Y, Cao Y, Cao Q, Lu Q, Zhou S, Liu L, Liu L, Shen B, Shu W, Huo R. Oocyte competence is maintained by m6A methyltransferase KIAA1429-mediated RNA metabolism during mouse follicular development. Cell Death Differ. 2020;[Epub] doi:10.1038/s41418-020-0516-1.

Identification of mecciRNAs and their roles in the mitochondrial entry of proteins

Authors:
Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G
Citation:
Sci China Life Sci. 2020;[Epub ahead of print] doi:10.1007/s11427-020-1631-9
Abstract:
Mammalian mitochondria have small genomes encoding very limited numbers of proteins. Over one thousand proteins and noncoding...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: 293T
Citation Extract:
Liu X, Wang X, Li J, Hu S, Deng Y, Yin H, Bao X, Zhang QC, Wang G, Wang B, Shi Q, Shan G. Identification of mecciRNAs and their roles in the mitochondrial entry of proteins. Sci China Life Sci. 2020;[Epub ahead of print] doi:10.1007/s11427-020-1631-9.

Transient receptor potential vanilloid 4 modulates ion balance through the isotocin pathway in zebrafish (Danio rerio)

Authors:
Liu ST, Chou MY, Wu LC, Horng JL, Lin LY
Citation:
Am J Physiol Regul Integr Comp Physiol. 2020;[Epub ahead of print] doi:10.1152/ajpregu.00307.2019
Abstract:
Isotocin controls ion regulation through modulating the functions of ionocytes (also called mitochondria-rich cells or chloride...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu ST, Chou MY, Wu LC, Horng JL, Lin LY. Transient receptor potential vanilloid 4 modulates ion balance through the isotocin pathway in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2020;[Epub ahead of print] doi:10.1152/ajpregu.00307.2019.

REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects

Authors:
Lee S-H, Hadipour-Lakmehsari S, Murthy HR, Gibb N, Miyake T, Teng ACT, Cosme J, Yu JC, Moon M, Lim SH, Wong V, Liu P, Billia F, Fernandez-Gonzalez R, Stagljar I, Sharma P, Kislinger T, Scott IC, Gramolini AO
Citation:
Nat Comm. 2020;11:965 doi:10.1038/s41467-019-14143-9
Abstract:
The sarco-endoplasmic reticulum (SR/ER) plays an important role in the development and progression of many heart diseases....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee S-H, Hadipour-Lakmehsari S, Murthy HR, Gibb N, Miyake T, Teng ACT, Cosme J, Yu JC, Moon M, Lim SH, Wong V, Liu P, Billia F, Fernandez-Gonzalez R, Stagljar I, Sharma P, Kislinger T, Scott IC, Gramolini AO. REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects. Nat Comm. 2020;11:965 doi:10.1038/s41467-019-14143-9.

Axonal precursor miRNAs hitchhike on endosomes and locally regulate the development of neural circuits

Authors:
Corradi E, Dalla Costa I, Gavoci A, Iyer A, Roccuzzo M, Otto TA, Oliani E, Bridi S, Strohbuecker S, Santos-Rodriguez G, Valdembri D, Serini G, Abreu-Goodger C, Baudet ML
Citation:
EMBO J. 2020 Feb 19:e102513. doi: 10.15252/embj.2019102513. [Epub ahead of print]
Abstract:
Various species of non‐coding RNAs (ncRNAs) are enriched in specific subcellular compartments, but the mechanisms orchestrating...
Delivery Method:
microinjection, electroporation
Organism or Cell Type:
Xenopus laevis embryo and cell culture
Citation Extract:
Corradi E, Dalla Costa I, Gavoci A, Iyer A, Roccuzzo M, Otto TA, Oliani E, Bridi S, Strohbuecker S, Santos-Rodriguez G, Valdembri D, Serini G, Abreu-Goodger C, Baudet ML. Axonal precursor miRNAs hitchhike on endosomes and locally regulate the development of neural circuits. EMBO J. 2020 Feb 19:e102513. doi: 10.15252/embj.2019102513. [Epub ahead of print].

Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube

Authors:
Symonds A, Buckley C, Williams C, Clarke J
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.02.16.950543
Abstract:
We uncover the mechanisms allowing the generation of two opposing apical epithelial surfaces within the centre of an initially...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Symonds A, Buckley C, Williams C, Clarke J. Coordinated assembly and release of adhesions builds apical junctional belts during de novo polarisation of an epithelial tube. bioRxiv. 2020;[preprint] doi:10.1101/2020.02.16.950543.

Neutrophils use selective autophagy receptor p62/SQSTM1 to target Staphylococcus aureus for degradation in vivo in zebrafish

Authors:
Gibson JF, Prajsnar TK, Hill CJ, Tooke AK, Serba JJ, Tonge RD, Foster SJ, Grierson AJ, Ingham PW, Renshaw SA, Johnston SA
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/604884
Abstract:
Autophagy leads to degradation of cellular components and has an important role in restricting intracellular pathogens....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gibson JF, Prajsnar TK, Hill CJ, Tooke AK, Serba JJ, Tonge RD, Foster SJ, Grierson AJ, Ingham PW, Renshaw SA, Johnston SA. Neutrophils use selective autophagy receptor p62/SQSTM1 to target Staphylococcus aureus for degradation in vivo in zebrafish. bioRxiv. 2020;[preprint] doi:10.1101/604884.

Pou5f3 and Sox19b select gene expression repertoire at Zygotic Genome Activation

Authors:
Gao M, Veil M, Rosenblatt M, Gebhard A, Hass H, Buryanova L, Yampolsky LY, Grüning B, Timmer J, Onichtchouk D
Citation:
bioRxiv. 2020:[preprint] doi:10.1101/2020.02.16.949362
Abstract:
PouV and SoxB1 family transcription factors (TFs) have emerged as master regulators of cell fate transitions. To investigate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao M, Veil M, Rosenblatt M, Gebhard A, Hass H, Buryanova L, Yampolsky LY, Grüning B, Timmer J, Onichtchouk D. Pou5f3 and Sox19b select gene expression repertoire at Zygotic Genome Activation. bioRxiv. 2020:[preprint] doi:10.1101/2020.02.16.949362 .

Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities [abstract]

Authors:
Soto-Pantoja D, Clear K, Cook KL
Citation:
Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-14-19. doi:10.1158/1538-7445.SABCS19-P5-14-19
Abstract:
Background: The unfolded protein response (UPR) is an endoplasmic reticulum pathway stimulated when the protein folding demand...
Organism or Cell Type:
mouse xenograft 4T1-luciferase triple negative breast cancer cells
Citation Extract:
Soto-Pantoja D, Clear K, Cook KL. Targeting the unfolded protein response components differentially sensitizes breast tumors to doxorubicin while modulating chemotherapy-induced cardiotoxicities [abstract]. Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P5-14-19. doi:10.1158/1538-7445.SABCS19-P5-14-19.

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