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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12538 scientific papers returned from the database with the search filters currently being used below.
There are 12538 scientific papers returned from the database with the search filters currently being used below.
Production of offspring via the transplantation of frozen germ cells from Tokyo bitterling, a fish on the brink of extinction
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Citation:
Sci Rep. 2025 Nov 19;15(1):40759. doi: 10.1038/s41598-025-24449-y. PMID: 41258175; PMCID: PMC12630933 Epub:
Not Epub Abstract:
Many freshwater fish face extinctions due to habitat destruction and overfishing. Bitterlings, which lay their eggs in the gill... Delivery Method:
microinjection Organism or Cell Type:
Tokyo bitterling Citation Extract: Yamakawa K, Kawaguchi K, Yoshizaki G. Production of offspring via the transplantation of frozen germ cells from Tokyo bitterling, a fish on the brink of extinction. Sci Rep. 2025 Nov 19;15(1):40759. doi: 10.1038/s41598-025-24449-y. PMID: 41258175; PMCID: PMC12630933. |
Dual origins for neural cells during development of the Clytia planula larva
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Citation:
bioRxiv [preprint] 2025.11.17.688882; doi: https://doi.org/10.1101/2025.11.17.688882 Epub:
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Adult hydrozoan cnidarians undergo extensive tissue turnover, generating neural cell types including nematocytes (stinging... Delivery Method:
microinjection Organism or Cell Type:
Clytia (Phialidium) gregarium gastrula-stage embryos Citation Extract: Ruggiero A, Ferraioli A, Chevalier S, Lapébie P, Girard R, Momose T, Barreau C, Houliston E. Dual origins for neural cells during development of the Clytia planula larva. bioRxiv [preprint] 2025.11.17.688882; doi: https://doi.org/10.1101/2025.11.17.688882. |
Collagen processing is essential for germ cell identity
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Citation:
Biol Open. 2025 Nov 15;14(11):bio062198. doi: 10.1242/bio.062198. Epub 2025 Nov 20. PMID: 41263153 Epub:
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The extracellular matrix (ECM) is a critical component of embryonic development, providing both structural support and a... Delivery Method:
microinjection Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Roman S, Oulhen N, Reyes G, Masina B, Wessel G. Collagen processing is essential for germ cell identity. Biol Open. 2025 Nov 15;14(11):bio062198. doi: 10.1242/bio.062198. Epub 2025 Nov 20. PMID: 41263153. |
DNA methyltransferase Dnmt3ba-mediated epigenetic modulation of Integrin signaling is essential for hematopoietic stem and progenitor cell development
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Citation:
Commun Biol. 2025 Nov 19;8(1):1612. doi: 10.1038/s42003-025-09003-w. PMID: 41261168; PMCID: PMC12630766 Epub:
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In vertebrate embryonic development, hematopoietic stem and progenitor cells (HSPCs) originate from a subset of arterial... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ai K, Wu Y, Liang G, Kong H, Yang X, Li N, Liu Z, Dong Y, Xu J, Zhang L, Chen X, Fu Y, Wang L, Li L. DNA methyltransferase Dnmt3ba-mediated epigenetic modulation of Integrin signaling is essential for hematopoietic stem and progenitor cell development. Commun Biol. 2025 Nov 19;8(1):1612. doi: 10.1038/s42003-025-09003-w. PMID: 41261168; PMCID: PMC12630766. |
A microscopy-based CRISPR screening platform enables organellar functional genomics and illuminates ciliary biology
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Citation:
Dev Cell. 2025 Nov 20:S1534-5807(25)00666-5. doi: 10.1016/j.devcel.2025.10.015. Epub ahead of print. PMID: 41270742 Epub:
Not Epub Abstract:
Microscopy offers an indispensable technique for visualizing biological processes and for defining cytological abnormalities... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Sun J, Atiş IS, Empke SLL, Khokha MK, Breslow DK. A microscopy-based CRISPR screening platform enables organellar functional genomics and illuminates ciliary biology. Dev Cell. 2025 Nov 20:S1534-5807(25)00666-5. doi: 10.1016/j.devcel.2025.10.015. Epub ahead of print. PMID: 41270742. |
NF2 lacking exon 11 induced by antisense gene therapy is able to partially recover merlin deficiency on NF2-SWN iPSC-derived spheroid model
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Citation:
bioRxiv 2025.11.14.688164; doi: https://doi.org/10.1101/2025.11.14.688164 Epub:
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NF2-related Schwannomatosis (NF2-SWN) is an inherited autosomal dominant disorder resulting from loss-of-function mutations in... Delivery Method:
Endo-Porter for iPSCs differentiated into neural crest (NC) spheroids, Vivo-Morpholino for Schwann cell spheroids differentiated from NC cells Organism or Cell Type:
NF2-SWN patient-derived primary fibroblasts Citation Extract: Casals-Sendra G, Jarne-Sanz I, Catasús N, Boluda-Luis I, Quer A, Amilibia E, Lázaro C, Serra E, Blanco I, Castellanos E. NF2 lacking exon 11 induced by antisense gene therapy is able to partially recover merlin deficiency on NF2-SWN iPSC-derived spheroid model. bioRxiv 2025.11.14.688164; doi: https://doi.org/10.1101/2025.11.14.688164. |
Zebrafish col4a1 loss-of-function models mirror key neurovascular and ocular features of COL4A1/A2 syndrome and enable human variants assessment in vivo
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Citation:
Matrix Biol. 2025 Nov 15:S0945-053X(25)00108-8. doi: 10.1016/j.matbio.2025.11.004. Epub ahead of print. PMID: 41248836 Epub:
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Pathogenic variants in COL4A1 and COL4A2, encoding type IV collagen α1 and α2 chains-core components of all basement membranes-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Paradisi G, Bonavolontà V, Venditti M, Fasano G, Pedalino C, Bene FD, Tartaglia M, Lauri A. Zebrafish col4a1 loss-of-function models mirror key neurovascular and ocular features of COL4A1/A2 syndrome and enable human variants assessment in vivo. Matrix Biol. 2025 Nov 15:S0945-053X(25)00108-8. doi: 10.1016/j.matbio.2025.11.004. Epub ahead of print. PMID: 41248836. |
Sox8 is essential for vertebrate gastrulation
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Citation:
EMBO Rep. 2025 Nov 10. doi: 10.1038/s44319-025-00617-z. Epub ahead of print. PMID: 41214364 Epub:
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Gastrulation is a fundamental developmental process during which germ layers are formed and the body axes are defined by the... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Moreira S, Korovesi AG, Barriga EH. Sox8 is essential for vertebrate gastrulation. EMBO Rep. 2025 Nov 10. doi: 10.1038/s44319-025-00617-z. Epub ahead of print. PMID: 41214364. |
CANTAC-seq analysis reveals E2f1 and Otx1 coordinate zygotic genome activation in Xenopus tropicalis
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Citation:
Nat Commun. 2025 Nov 18;16(1):10101. doi: 10.1038/s41467-025-65146-8. PMID: 41253814 Epub:
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Zygotic genome activation is tightly associated with the modulation of chromatin accessibility via maternal transcription... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Cui H, Liang W, Shi Z, Zhang L, Li G, Chen R, Tian C, Gan D, Shi X, Sun Z, Zhu Q, Fang L, Huang H, Hu Y, Chen Y, Chen W. CANTAC-seq analysis reveals E2f1 and Otx1 coordinate zygotic genome activation in Xenopus tropicalis. Nat Commun. 2025 Nov 18;16(1):10101. doi: 10.1038/s41467-025-65146-8. PMID: 41253814. |
Mechanochemical mechanism underlying intercellular Ca2+ wave propagation and its crucial role in apoptotic cell extrusion
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Citation:
Nat Commun. 2025 Nov 17;16(1):9887. doi: 10.1038/s41467-025-65474-9. PMID: 41249134; PMCID: PMC12623941 Epub:
Not Epub Abstract:
Calcium (Ca2+) wave propagation plays a crucial role in intercellular communication. Elevation of cytosolic Ca2+ (Ca2+... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yamada S, Yasukuni R, Bessho Y, Fujita Y, Hosokawa Y, Matsui T. Mechanochemical mechanism underlying intercellular Ca2+ wave propagation and its crucial role in apoptotic cell extrusion. Nat Commun. 2025 Nov 17;16(1):9887. doi: 10.1038/s41467-025-65474-9. PMID: 41249134; PMCID: PMC12623941. |