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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9496 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

The human nephrin Y1139RSL motif is essential for podocyte foot process organization and slit diaphragm formation during glomerular development

Authors:
Espiritu EB, Jiang H, Moreau-Marquis S, Sullivan M, Yan K, Beer Stolz D, Sampson MG, Hukriede NA, Swiatecka-Urban A
Citation:
J Biol Chem. 2019 May 31. pii: jbc.RA119.008235. doi: 10.1074/jbc.RA119.008235. [Epub ahead of print]
Abstract:
Nephrin is an immunoglobulin-type cell-adhesion molecule with a key role in the glomerular interpodocyte slit diaphragm....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Espiritu EB, Jiang H, Moreau-Marquis S, Sullivan M, Yan K, Beer Stolz D, Sampson MG, Hukriede NA, Swiatecka-Urban A. The human nephrin Y1139RSL motif is essential for podocyte foot process organization and slit diaphragm formation during glomerular development. J Biol Chem. 2019 May 31. pii: jbc.RA119.008235. doi: 10.1074/jbc.RA119.008235. [Epub ahead of print].

Pectoral Fin Anomalies in tbx5a Knockdown Zebrafish Embryos Related to the Cascade Effect of N-Cadherin and Extracellular Matrix Formation

Authors:
Lu JK, Tsai T-C, Lee H, Hsia K, Lin C-H, Lu J-H
Citation:
J Dev Biol. 2019;7(3):[Epub ahead of print] doi:10.3390/jdb7030015
Abstract:
Functional knockdown of zebrafish tbx5a causes hypoplasia or aplasia of pectoral fins. This study aimed to assess developmental...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu JK, Tsai T-C, Lee H, Hsia K, Lin C-H, Lu J-H. Pectoral Fin Anomalies in tbx5a Knockdown Zebrafish Embryos Related to the Cascade Effect of N-Cadherin and Extracellular Matrix Formation. J Dev Biol. 2019;7(3):[Epub ahead of print] doi:10.3390/jdb7030015.

Zebrafish Wtx is a negative regulator of Wnt signaling but is dispensable for embryonic development and organ homeostasis

Authors:
Große A, Perner B, Naumann U, Englert C
Citation:
Dev Dyn. 2019 Jul 10. doi: 10.1002/dvdy.84. [Epub ahead of print]
Abstract:
BACKGROUND: The X-chromosomally linked gene WTX is a human disease gene and a member of the AMER family. Mutations in WTX are...
Organism or Cell Type:
zebrafish
Citation Extract:
Große A, Perner B, Naumann U, Englert C. Zebrafish Wtx is a negative regulator of Wnt signaling but is dispensable for embryonic development and organ homeostasis. Dev Dyn. 2019 Jul 10. doi: 10.1002/dvdy.84. [Epub ahead of print].

High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration

Authors:
Owens DA, Butler AM, Aguero TH, Newman KM, Van Booven D, King ML
Citation:
Development. 2017 Jan 15;144(2):292-304. doi: 10.1242/dev.139220
Abstract:
During oogenesis, hundreds of maternal RNAs are selectively localized to the animal or vegetal pole, including determinants of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Owens DA, Butler AM, Aguero TH, Newman KM, Van Booven D, King ML. High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration. Development. 2017 Jan 15;144(2):292-304. doi: 10.1242/dev.139220.

Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis

Authors:
Kim S, Chung A-H, Na JE, Lee SJ, Jeong SH, Kim E, Sun W, Rhyu IJ, Park H-C
Citation:
Glia. 2019;[Epub ahead of print] doi:10.1002/glia.23669
Abstract:
Myelin is a specialized membrane that wraps around nerve fibers and is essential for normal axonal conduction in neurons. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim S, Chung A-H, Na JE, Lee SJ, Jeong SH, Kim E, Sun W, Rhyu IJ, Park H-C. Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis. Glia. 2019;[Epub ahead of print] doi:10.1002/glia.23669.

Tfap2a is a novel gatekeeper of nephron differentiation during kidney development

Authors:
Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA
Citation:
Development. 2019 Jun 3. pii: dev.172387. doi: 10.1242/dev.172387. [Epub ahead of print]
Abstract:
Renal functional units known as nephrons undergo patterning events during development that create a segmental array of cellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA. Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development. 2019 Jun 3. pii: dev.172387. doi: 10.1242/dev.172387. [Epub ahead of print].

Notch-mediated inhibition of neurogenesis is required for zebrafish spinal cord morphogenesis

Authors:
Sharma P, Saraswathy VM, Xiang L, Fürthauer M
Citation:
Sci Rep. 2019;9(1):9958. doi:10.1038/s41598-019-46067-1
Abstract:
The morphogenesis of the nervous system requires coordinating the specification and differentiation of neural precursor cells,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma P, Saraswathy VM, Xiang L, Fürthauer M. Notch-mediated inhibition of neurogenesis is required for zebrafish spinal cord morphogenesis. Sci Rep. 2019;9(1):9958. doi:10.1038/s41598-019-46067-1.

Heroin Cue-Evoked Astrocytic Structural Plasticity at Nucleus Accumbens Synapses Inhibits Heroin Seeking

Authors:
Kruyer A, Scofield MD, Wood D, Reissner KJ, Kalivas PW
Citation:
Biol Psych. 2019;[Epub ahead of print] doi:10.1016/j.biopsych.2019.06.026
Abstract:
Background: Opioid addiction is a critical medical and social problem characterized by vulnerability to relapse. Glutamatergic...
Delivery Method:
bilateral NAcore brain infusion Vivo-Morpholino
Organism or Cell Type:
Rats Sprague-Dawley male
Citation Extract:
Kruyer A, Scofield MD, Wood D, Reissner KJ, Kalivas PW. Heroin Cue-Evoked Astrocytic Structural Plasticity at Nucleus Accumbens Synapses Inhibits Heroin Seeking. Biol Psych. 2019;[Epub ahead of print] doi:10.1016/j.biopsych.2019.06.026.

The role of maternal pioneer factors in predefining first zygotic responses to inductive signals

Authors:
Gentsch GE, Spruce T, Owens NDL, Smith JC
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/306803
Abstract:
Embryonic development yields many different cell types in response to just a few families of inductive signals. The property of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Gentsch GE, Spruce T, Owens NDL, Smith JC. The role of maternal pioneer factors in predefining first zygotic responses to inductive signals. bioRxiv. 2019;[preprint] doi:10.1101/306803 .

The lncRNAs Implicated in Redox Regulation in Ybx1 Deficient Zebrafish Larvae

Authors:
Huang C, Zhu B, Leng D, Ge W, Zhang XD
Citation:
bioRxiv. 2019;[preprint] doi:/10.1101/679167
Abstract:
Ybx1 has been demonstrated as a crucial gene in embryogenesis, reproduction as well as development in various vertebrates such...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang C, Zhu B, Leng D, Ge W, Zhang XD. The lncRNAs Implicated in Redox Regulation in Ybx1 Deficient Zebrafish Larvae. bioRxiv. 2019;[preprint] doi:/10.1101/679167.

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