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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9288 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth

Authors:
Zhang Y, Ji D, Li L, Yang S, Zhang H, Duan X
Citation:
Theranostics. 2019;9(5):1387-1400. doi:10.7150/thno.29761
Abstract:
Human CLCN7 encodes voltage-gated chloride channel 7 (ClC-7); mutations of CLCN7 lead to osteopetrosis which is characterized...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Ji D, Li L, Yang S, Zhang H, Duan X. ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth. Theranostics. 2019;9(5):1387-1400. doi:10.7150/thno.29761.

Tulotta C, Stefanescu C, Chen Q, Torraca V, Meijer AH, Snaar-Jagalska BE

Authors:
CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells
Citation:
Sci Rep. 2019;9:2399 doi:10.1038/s41598-019-38643-2
Abstract:
Developing tumors interact with the surrounding microenvironment. Myeloid cells exert both anti- and pro-tumor functions and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells. Tulotta C, Stefanescu C, Chen Q, Torraca V, Meijer AH, Snaar-Jagalska BE. Sci Rep. 2019;9:2399 doi:10.1038/s41598-019-38643-2.

Microinjection methods for sea urchin eggs and blastomeres

Authors:
Yaguchi J
Citation:
Methods Cell Biol. 2019;150:173-188. doi: 10.1016/bs.mcb.2018.09.013. Epub 2019 Jan 28
Abstract:
Methods for microinjection into sea urchin eggs have become relatively easier because of the technical improvements by a number...
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus, Temnopleurus reevesii, Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Yaguchi J. Microinjection methods for sea urchin eggs and blastomeres. Methods Cell Biol. 2019;150:173-188. doi: 10.1016/bs.mcb.2018.09.013. Epub 2019 Jan 28.

Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

Authors:
Young RM, Hawkins TA, Cavodeassi F, Stickney HL, Schwarz Q, Lawrence LM, Wierzbicki C, Cheng BYL, Luo J, Ambrosio EM, Klosner A, Sealy IM, Rowell J, Trivedi CA, Bianco IH, Allende ML, Busch-Nentwich EM, Gestri G, Wilson SW
Citation:
eLife. 2019;8:e40093 doi:10.7554/eLife.40093
Abstract:
The vertebrate eye originates from the eye field, a domain of cells specified by a small number of transcription factors. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Young RM, Hawkins TA, Cavodeassi F, Stickney HL, Schwarz Q, Lawrence LM, Wierzbicki C, Cheng BYL, Luo J, Ambrosio EM, Klosner A, Sealy IM, Rowell J, Trivedi CA, Bianco IH, Allende ML, Busch-Nentwich EM, Gestri G, Wilson SW. Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification. eLife. 2019;8:e40093 doi:10.7554/eLife.40093.

Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function

Authors:
Li X-J, Zhu L, Chen L, Yan L, Perkins B, Li S, Li B, Xu HA
Citation:
Front Cell Neurosci. 2019;[Epub] doi:doi: 10.3389/fncel.2019.00081
Abstract:
Joubert syndrome (JBTS) is an inherited autosomal recessive disorder associated with cerebellum and brainstem malformation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X-J, Zhu L, Chen L, Yan L, Perkins B, Li S, Li B, Xu HA. Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function. Front Cell Neurosci. 2019;[Epub] doi:doi: 10.3389/fncel.2019.00081.

Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos

Authors:
Vázquez-Diez C, Paim LMG, FitzHarris G
Citation:
Curr Biol. 2019 Jan 17. pii: S0960-9822(18)31676-2. doi: 10.1016/j.cub.2018.12.042. [Epub ahead of print]
Abstract:
Chromosome segregation errors during mammalian preimplantation development cause "mosaic" embryos comprising a...
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Vázquez-Diez C, Paim LMG, FitzHarris G. Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos. Curr Biol. 2019 Jan 17. pii: S0960-9822(18)31676-2. doi: 10.1016/j.cub.2018.12.042. [Epub ahead of print].

BMP signaling is required for amphioxus tail regeneration

Authors:
Liang Y, Rathnayake D, Huang S, Pathirana A, Xu Q, Zhang S
Citation:
Development. 2019 Jan 29. pii: dev.166017. doi: 10.1242/dev.166017. [Epub ahead of print]
Abstract:
Amphioxus, a cephalochordate, is an ideal animal in which to address questions about the evolution of regenerative ability and...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Branchiostoma japonicum (amphioxus)
Citation Extract:
Liang Y, Rathnayake D, Huang S, Pathirana A, Xu Q, Zhang S. BMP signaling is required for amphioxus tail regeneration. Development. 2019 Jan 29. pii: dev.166017. doi: 10.1242/dev.166017. [Epub ahead of print].

BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish

Authors:
Li L, Ning G, Yang S, Yan Y, Cao Y, Wang Q
Citation:
PLoS Genet. 2019;15(2):e1007996. https://doi.org/10.1371/journal.pgen.1007996
Abstract:
Pharyngeal pouches, a series of outpocketings that bud from the foregut endoderm, are essential to the formation of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li L, Ning G, Yang S, Yan Y, Cao Y, Wang Q. BMP signaling is required for nkx2.3-positive pharyngeal pouch progenitor specification in zebrafish. PLoS Genet. 2019;15(2):e1007996. https://doi.org/10.1371/journal.pgen.1007996.

A zebrafish model for MonoMAC syndrome identifies an earlier role for gata2 in haemogenic endothelium programming and generation of haematopoietic stem cells

Authors:
Dobrzycki T, Krecsmarik M, Koyunlar C, Rispoli R, Peulen-Zink J, Gussinklo K, de Pater E, Patient R, Monteiro R
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/516203
Abstract:
Haematopoietic stem and progenitor cells (HSPCs) maintain the vertebrate blood system throughout life and their emergence from...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dobrzycki T, Krecsmarik M, Koyunlar C, Rispoli R, Peulen-Zink J, Gussinklo K, de Pater E, Patient R, Monteiro R. A zebrafish model for MonoMAC syndrome identifies an earlier role for gata2 in haemogenic endothelium programming and generation of haematopoietic stem cells. bioRxiv. 2019;[Preprint] doi:10.1101/516203.

A contractile acto-myosin belt promotes growth anisotropy during the early stages of pectoral fin development in zebrafish

Authors:
Kardash E, Nguyen H, Behrndt M, Heisenberg C-P, Peyrieras N, Gonzalez-Gaitan M
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/512038
Abstract:
The zebrafish pectoral fin is an in vivo model for vertebrate limb formation, well suited to investigate the integration of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kardash E, Nguyen H, Behrndt M, Heisenberg C-P, Peyrieras N, Gonzalez-Gaitan M. A contractile acto-myosin belt promotes growth anisotropy during the early stages of pectoral fin development in zebrafish. bioRxiv. 2019;[Preprint] doi:10.1101/512038.

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