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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10101 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

The role of matrix metalloproteinase-9 (MMP-9) in neurodevelopmental deficits and experience-dependent structural plasticity in Xenopus laevis tadpoles

Authors:
Gore S, James EJ, Huang L-C, Park JJ, Berghella A, Cline HT, Aizenman CD
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.29.123661
Abstract:
Matrix metalloproteinase-9 is a secreted endopeptidase targeting extracellular matrix proteins, creating permissive...
Delivery Method:
electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gore S, James EJ, Huang L-C, Park JJ, Berghella A, Cline HT, Aizenman CD. The role of matrix metalloproteinase-9 (MMP-9) in neurodevelopmental deficits and experience-dependent structural plasticity in Xenopus laevis tadpoles. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.29.123661 .

Functional characterization of a "plant-like" HYL1 homolog in the cnidarian Nematostella vectensis indicates a conserved involvement in microRNA biogenesis

Authors:
Tripathi AM, Fridrich A, Lewandowska M, Moran Y
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.31.126003
Abstract:
While the biogenesis of microRNAs (miRNAs) in both animals and plants depends on Dicer, a conserved RNAse III enzyme, its...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (cniderian)
Citation Extract:
Tripathi AM, Fridrich A, Lewandowska M, Moran Y. Functional characterization of a "plant-like" HYL1 homolog in the cnidarian Nematostella vectensis indicates a conserved involvement in microRNA biogenesis. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.31.126003.

Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H+-ATPase Rich Ionocytes

Authors:
Tong S-K, Lee H-L, Lee Y-C, Wu L-C, Tsou Y-L, Lu S-W, Shih S-W, Hwang P-P, Chou M-Y
Citation:
Int J Mol Sci. 2020;21(11):9357. doi:10.3390/ijms21113957
Abstract:
Arginine vasopressin (Avp) is a conserved pleiotropic hormone that is known to regulate both water reabsorption and ion balance...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tong S-K, Lee H-L, Lee Y-C, Wu L-C, Tsou Y-L, Lu S-W, Shih S-W, Hwang P-P, Chou M-Y. Arginine Vasopressin Modulates Ion and Acid/Base Balance by Regulating Cell Numbers of Sodium Chloride Cotransporter and H+-ATPase Rich Ionocytes. Int J Mol Sci. 2020;21(11):9357. doi:10.3390/ijms21113957.

Ethanol and cannabinoids regulate zebrafish GABAergic neuron development and behavior in a sonic hedgehog and fibroblast growth factor dependent mechanism

Authors:
Boa-Amponsem O, Zhang C, Burton D, Williams KP, Cole GJ
Citation:
Alcohol Clin Exp Res. 2020 May 29. doi: 10.1111/acer.14383. Online ahead of print
Abstract:
Background: Ethanol has diverse effects on nervous system development, which includes development and survival of GABAergic...
Organism or Cell Type:
zebrafish
Citation Extract:
Boa-Amponsem O, Zhang C, Burton D, Williams KP, Cole GJ . Ethanol and cannabinoids regulate zebrafish GABAergic neuron development and behavior in a sonic hedgehog and fibroblast growth factor dependent mechanism. Alcohol Clin Exp Res. 2020 May 29. doi: 10.1111/acer.14383. Online ahead of print.

The Axenfeld-Rieger syndrome gene FOXC1 contributes to left-right patterning

Authors:
Chrystal PW, French CR, Jean F, Havrylov S, van Baarle S, Peturson A-M, Xu P, Crump JG, Pilgrim DB, Lehmann OJ, Waskiewicz AJ
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.28.120915
Abstract:
Normal body situs requires precise spatiotemporal expression of the Nodal-Lefty-Pitx2 cascade in the lateral plate mesoderm....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chrystal PW, French CR, Jean F, Havrylov S, van Baarle S, Peturson A-M, Xu P, Crump JG, Pilgrim DB, Lehmann OJ, Waskiewicz AJ. The Axenfeld-Rieger syndrome gene FOXC1 contributes to left-right patterning. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.28.120915 .

Neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and brain size in Xenopus embryos

Authors:
Willsey HR, Xu Y, Everitt A, Dea J, Exner CRT, Willsey AJ, State MW, Harland RM
Citation:
Development. 2020:dev.189290 {Epub ahead of print] doi: 10.1242/dev.189290
Abstract:
DYRK1A (dual specificity tyrosine-(Y)-phosphorylation-regulated kinase 1 A) is a high confidence autism risk gene that encodes...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Willsey HR, Xu Y, Everitt A, Dea J, Exner CRT, Willsey AJ, State MW, Harland RM. Neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and brain size in Xenopus embryos. Development. 2020:dev.189290 {Epub ahead of print] doi: 10.1242/dev.189290.

The stem-like STAT3-responsive cells of zebrafish intestine are WNT/β-catenin dependent

Authors:
Peron M, Dinarello A, Meneghetti G, Martorano L, Facchinello N, Vettori A, Gicciardello G, Tiso N, Argenton F
Citation:
Development. 2020;[Epub ahead of print] doi:10.1242/dev.188987
Abstract:
The transcription factor STAT3 is required for proliferation and pluripotency of embryonic stem cells; we have prepared and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Peron M, Dinarello A, Meneghetti G, Martorano L, Facchinello N, Vettori A, Gicciardello G, Tiso N, Argenton F. The stem-like STAT3-responsive cells of zebrafish intestine are WNT/β-catenin dependent. Development. 2020;[Epub ahead of print] doi:10.1242/dev.188987.

Tissue-Specific Requirement for the GINS Complex During Zebrafish Development

Authors:
Varga M, Csályi K, Bertyák I, Menyhárd DK, Poole RJ, Cerveny KL, Kövesdi D, Barátki B, Rouse H, Vad Z, Hawkins TA, Stickney HL, Cavodeassi F, Schwarz Q, Young RM, Wilson SW
Citation:
Front Cell Dev Biol. 2020;8:373. doi:10.3389/fcell.2020.00373
Abstract:
Efficient and accurate DNA replication is particularly critical in stem and progenitor cells for successful proliferation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Varga M, Csályi K, Bertyák I, Menyhárd DK, Poole RJ, Cerveny KL, Kövesdi D, Barátki B, Rouse H, Vad Z, Hawkins TA, Stickney HL, Cavodeassi F, Schwarz Q, Young RM, Wilson SW. Tissue-Specific Requirement for the GINS Complex During Zebrafish Development. Front Cell Dev Biol. 2020;8:373. doi:10.3389/fcell.2020.00373.

Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta

Authors:
Yvernogeau L, Klaus A, Maas J, Morin-Poulard I, Weijts B, Schulte-Merker S, Berezikov E, Junker JP, Robin C
Citation:
Blood. 2020;[Epub] doi:10.1182/blood.2019004446
Abstract:
The defined location of a stem cell within a niche regulates its fate, behavior and molecular identity via a complex extrinsic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yvernogeau L, Klaus A, Maas J, Morin-Poulard I, Weijts B, Schulte-Merker S, Berezikov E, Junker JP, Robin C. Multispecies RNA tomography reveals regulators of hematopoietic stem cell birth in the embryonic aorta. Blood. 2020;[Epub] doi:10.1182/blood.2019004446.

The H3.3 chaperone Hira complex orchestrates oocyte developmental competence

Authors:
Smith R, Jiang Z, Susor A, Ming H, Tait J, Conti M, Lin C-J
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.25.114124
Abstract:
Reproductive success relies on a healthy oocyte competent for fertilisation and capable of sustaining early embryo development...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Smith R, Jiang Z, Susor A, Ming H, Tait J, Conti M, Lin C-J. The H3.3 chaperone Hira complex orchestrates oocyte developmental competence. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.25.114124 .

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