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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9716 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Ciglitazone - a human PPARγ agonist - disrupts dorsoventral patterning in zebrafish

Authors:
Cheng V, Dasgupta S, Reddam A, Volz DC
Citation:
PeerJ. 2019;7:e8054 doi:10.7717/peerj.8054
Abstract:
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng V, Dasgupta S, Reddam A, Volz DC. Ciglitazone - a human PPARγ agonist - disrupts dorsoventral patterning in zebrafish. PeerJ. 2019;7:e8054 doi:10.7717/peerj.8054.

Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies

Authors:
Tsai IC, Adams KA, Tzeng JA, Shennib O, Tan PL, Katsanis N
Citation:
JCI Insight. 2019 Nov 14;4(22). pii: 130516. doi: 10.1172/jci.insight.130516
Abstract:
The ciliopathies are a group of phenotypically overlapping disorders caused by structural or functional defects in the primary...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsai IC, Adams KA, Tzeng JA, Shennib O, Tan PL, Katsanis N. Genome-wide suppressor screen identifies USP35/USP38 as therapeutic candidates for ciliopathies. JCI Insight. 2019 Nov 14;4(22). pii: 130516. doi: 10.1172/jci.insight.130516.

Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish

Authors:
Coombs C, Georgantzoglou A, Walker HA, Patt J, Merten N, Poplimont H, Busch-Nentwich EM, Williams S, Kotsi C, Kostenis E, Sarris M
Citation:
Nat Commun. 2019 Nov 14;10(1):5166. doi: 10.1038/s41467-019-13107-3
Abstract:
Immune cells congregate at specific loci to fight infections during inflammatory responses, a process that must be transient...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Coombs C, Georgantzoglou A, Walker HA, Patt J, Merten N, Poplimont H, Busch-Nentwich EM, Williams S, Kotsi C, Kostenis E, Sarris M. Chemokine receptor trafficking coordinates neutrophil clustering and dispersal at wounds in zebrafish. Nat Commun. 2019 Nov 14;10(1):5166. doi: 10.1038/s41467-019-13107-3.

Tfam knockdown results in reduction of mtDNA copy number, OXPHOS deficiency and abnormalities in zebrafish embryos

Authors:
Otten ABC, Kamps R, Lindsey P, Gerards M, Pendeville-Samain H, Muller M, van Tienen FHJ, Smeets HJM
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/843318
Abstract:
High mitochondrial DNA (mtDNA) copy numbers are essential for oogenesis and embryogenesis and correlate with fertility of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Otten ABC, Kamps R, Lindsey P, Gerards M, Pendeville-Samain H, Muller M, van Tienen FHJ, Smeets HJM. Tfam knockdown results in reduction of mtDNA copy number, OXPHOS deficiency and abnormalities in zebrafish embryos. bioRxiv. 2019;[preprint] doi:10.1101/843318 .

von Willebrand Factor D and EGF Domains is an evolutionarily conserved and required feature of blastemas capable of multi-tissue appendage regeneration

Authors:
Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/842948
Abstract:
Regenerative ability varies tremendously across species. A common feature of regeneration of appendages such as limbs, fins,...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Ambystoma mexicanum (Axolotl)
Citation Extract:
Leigh ND, Sessa S, Dragalzew AC, Payzin-Dogru D, Sousa JF, Aggouras AN, Johnson K, Dunlap GS, Haas BJ, Levin M, Schneider I, Whited JL. von Willebrand Factor D and EGF Domains is an evolutionarily conserved and required feature of blastemas capable of multi-tissue appendage regeneration. bioRxiv. 2019;[preprint] doi:10.1101/842948.

Role of the visual experience-dependent nascent proteome in neuronal plasticity

Authors:
Liu HH, McClatchy DB, Schiapparelli L, Shen W, Yates JR 3rd, Cline HT
Citation:
Elife. 2018 Feb 7;7. pii: e33420. doi: 10.7554/eLife.33420
Abstract:
Experience-dependent synaptic plasticity refines brain circuits during development. To identify novel protein synthesis-...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Liu HH, McClatchy DB, Schiapparelli L, Shen W, Yates JR 3rd, Cline HT. Role of the visual experience-dependent nascent proteome in neuronal plasticity. Elife. 2018 Feb 7;7. pii: e33420. doi: 10.7554/eLife.33420.

HDAC3 But not HDAC2 Mediates Visual Experience-Dependent Radial Glia Proliferation in the Developing Xenopus Tectum

Authors:
Gao J, Ruan H, Qi X, Tao Y, Guo X, Shen W
Citation:
Front Cell Neurosci. 2016 Sep 27;10:221. eCollection 2016
Abstract:
Radial glial cells (RGs) are one of the important progenitor cells that can differentiate into neurons or glia to form...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gao J, Ruan H, Qi X, Tao Y, Guo X, Shen W. HDAC3 But not HDAC2 Mediates Visual Experience-Dependent Radial Glia Proliferation in the Developing Xenopus Tectum. Front Cell Neurosci. 2016 Sep 27;10:221. eCollection 2016.

Adamts18 deficiency in zebrafish embryo causes defective trunk angiogenesis and caudal vein plexus formation

Authors:
Lu T, Zhang T, Wang C, Yang N, Pan YH, Dang S, Zhang W
Citation:
Biochem Biophys Res Commun. 2019 Nov 8. pii: S0006-291X(19)32118-7. doi: 10.1016/j.bbrc.2019.10.202. [Epub ahead of print]
Abstract:
ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin type I motifs) enzymes play an important role in various...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu T, Zhang T, Wang C, Yang N, Pan YH, Dang S, Zhang W. Adamts18 deficiency in zebrafish embryo causes defective trunk angiogenesis and caudal vein plexus formation. Biochem Biophys Res Commun. 2019 Nov 8. pii: S0006-291X(19)32118-7. doi: 10.1016/j.bbrc.2019.10.202. [Epub ahead of print].

The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension

Authors:
Morikawa M, Mitani Y, Holmborn K, Kato T, Koinuma D, Maruyama J, Vasilaki E, Sawada H, Kobayashi M, Ozawa T, Morishita Y, Bessho Y, Maeda S, Ledin J, Aburatani H, Kageyama R, Maruyama K, Heldin C-H, Miyazono K
Citation:
Sci Signal. 2019;12(607):eaay4430. doi:10.1126/scisignal.aay4430
Abstract:
Dysregulated bone morphogenetic protein (BMP) signaling in endothelial cells (ECs) is implicated in vascular diseases such as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morikawa M, Mitani Y, Holmborn K, Kato T, Koinuma D, Maruyama J, Vasilaki E, Sawada H, Kobayashi M, Ozawa T, Morishita Y, Bessho Y, Maeda S, Ledin J, Aburatani H, Kageyama R, Maruyama K, Heldin C-H, Miyazono K. The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension. Sci Signal. 2019;12(607):eaay4430. doi:10.1126/scisignal.aay4430 .

[Evaluation of Morpholino antisense oligos' role on BCR-ABL gene silencing in the K562 cell line]

Authors:
Haririan M, Kaviani S, Soleimani M, Noruzinia M, Abroun S, Rasi Ghaemi S, Delalat B
Citation:
Yakhteh Medical Journal. 2010;12(2):241-248
Abstract:
Objective: Chronic myeloid leukemia (CML) develops when a hematopoietic stem cell acquires the BCR/ABL fusion gene. This causes...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: K562, Jurkat
Citation Extract:
Haririan M, Kaviani S, Soleimani M, Noruzinia M, Abroun S, Rasi Ghaemi S, Delalat B. [Evaluation of Morpholino antisense oligos' role on BCR-ABL gene silencing in the K562 cell line]. Yakhteh Medical Journal. 2010;12(2):241-248.

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