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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12067 scientific papers returned from the database with the search filters currently being used below.

Investigation of the pathogenesis of ADAR1 gene in dyschromatosis symmetrica hereditaria

Authors:
Zhang J, Jiang C, Wang Z, Fang B, He J, Li M
Citation:
Exp Dermatol. 2024 Feb;33(2):e15031. doi: 10.1111/exd.15031
Epub:
Not Epub
Abstract:
The pathogenesis of dyschromatosis symmetrica hereditaria (DSH) has not been well defined. In this study, we sought to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang J, Jiang C, Wang Z, Fang B, He J, Li M. Investigation of the pathogenesis of ADAR1 gene in dyschromatosis symmetrica hereditaria. Exp Dermatol. 2024 Feb;33(2):e15031. doi: 10.1111/exd.15031.

Protocol for tail vein injection in Xenopus tropicalis tadpoles

Authors:
Patel JH, Angell Swearer A, Kakebeen AD, Loh LR, Wills AE
Citation:
STAR Protoc. 2024 Feb 16;5(1):102895. doi: 10.1016/j.xpro.2024.102895. Online ahead of print
Epub:
Not Epub
Abstract:
Functional studies in post-embryonic Xenopus tadpoles are challenging because embryonic perturbations often lead to...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Patel JH, Angell Swearer A, Kakebeen AD, Loh LR, Wills AE. Protocol for tail vein injection in Xenopus tropicalis tadpoles. STAR Protoc. 2024 Feb 16;5(1):102895. doi: 10.1016/j.xpro.2024.102895. Online ahead of print.

Long-range chemical signalling in vivo is regulated by mechanical signals

Authors:
Pillai EK, Mukherjee S, Gampl N, McGinn RJ, Mooslehner KA, Thompson AJ, Franze K
Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.02.15.580459
Epub:
Not Epub
Abstract:
Biological processes are regulated by chemical signals (e.g., morphogens, growth factors, and guidance cues) and mechanical...
Delivery Method:
microinjection, injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Pillai EK, Mukherjee S, Gampl N, McGinn RJ, Mooslehner KA, Thompson AJ, Franze K. Long-range chemical signalling in vivo is regulated by mechanical signals. bioRxiv. 2024;[preprint] doi:10.1101/2024.02.15.580459 .

FARS2 Deficiency Causes Cardiomyopathy by Disrupting Mitochondrial Homeostasis and the Mitochondrial Quality Control System

Authors:
Li B, Liu F, Chen X, Chen T, Zhang J, Liu Y, Yao Y, Hu W, Zhang M, Wang B, Liu L, Chen K, Wu Y
Citation:
Circulation. 2024 Feb 16. doi: 10.1161/CIRCULATIONAHA.123.064489. Online ahead of print
Epub:
Yes
Abstract:
Background: Hypertrophic cardiomyopathy (HCM) is a common heritable myocardiopathy. Although HCM has been reported to be...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li B, Liu F, Chen X, Chen T, Zhang J, Liu Y, Yao Y, Hu W, Zhang M, Wang B, Liu L, Chen K, Wu Y. FARS2 Deficiency Causes Cardiomyopathy by Disrupting Mitochondrial Homeostasis and the Mitochondrial Quality Control System. Circulation. 2024 Feb 16. doi: 10.1161/CIRCULATIONAHA.123.064489. Online ahead of print.

Clinical, immunohistochemical, and genetic characterization of splice-altering biallelic DES variants: Therapeutic implications

Authors:
Geist Hauserman J, Laverty CG, Donkervoort S, Hu Y, Silverstein S, Neuhaus SB, Saade D, Vaughn G, Malicki D, Kaur R, Li Y, Luo Y, Liu P, Burr P, Foley AR, Mohassel P, Bönnemann CG
Citation:
HGG Adv. 2024 Feb 2;5(2):100274. doi: 10.1016/j.xhgg.2024.100274. Online ahead of print
Epub:
Not Epub
Abstract:
Pathogenic variants in the DES gene clinically manifest as progressive skeletal muscle weakness, cardiomyopathy with associated...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: P1
Citation Extract:
Geist Hauserman J, Laverty CG, Donkervoort S, Hu Y, Silverstein S, Neuhaus SB, Saade D, Vaughn G, Malicki D, Kaur R, Li Y, Luo Y, Liu P, Burr P, Foley AR, Mohassel P, Bönnemann CG. Clinical, immunohistochemical, and genetic characterization of splice-altering biallelic DES variants: Therapeutic implications. HGG Adv. 2024 Feb 2;5(2):100274. doi: 10.1016/j.xhgg.2024.100274. Online ahead of print.

Localization and function of key axonemal microtubule inner proteins and dynein docking complex members reveal extensive diversity among vertebrate motile cilia

Authors:
Roy S, Lu H, Twan WK, Ikawa Y, Khare VP, Mukherjee I, Chua KX, Chakrabarti S, Hamada H
Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.02.14.580281
Epub:
Not Epub
Abstract:
Vertebrate motile cilia are broadly classified as (9+2) or (9+0), based on the presence or absence of the central pair...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roy S, Lu H, Twan WK, Ikawa Y, Khare VP, Mukherjee I, Chua KX, Chakrabarti S, Hamada H. Localization and function of key axonemal microtubule inner proteins and dynein docking complex members reveal extensive diversity among vertebrate motile cilia. bioRxiv. 2024;[preprint] doi:10.1101/2024.02.14.580281.

Zebrafish Mbd5 binds to RNA m5C and regulates histone deubiquitylation and gene expression in development metabolism and behavior

Authors:
Guo J, Zou Z, Dou X, Zhao X, Wang Y, Wei L, Pi Y, Wang Y, He C, Guo S
Citation:
Nucleic Acids Res. 2024;[Epub]:gkae093. doi:10.1093/nar/gkae093
Epub:
Not Epub
Abstract:
Complex biological processes are regulated by both genetic and epigenetic programs. One class of epigenetic modifications is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guo J, Zou Z, Dou X, Zhao X, Wang Y, Wei L, Pi Y, Wang Y, He C, Guo S. Zebrafish Mbd5 binds to RNA m5C and regulates histone deubiquitylation and gene expression in development metabolism and behavior. Nucleic Acids Res. 2024;[Epub]:gkae093. doi:10.1093/nar/gkae093.

Apela promotes blood vessel regeneration and remodeling in zebrafish

Authors:
Nys N, Khatib AM, Siegfried G
Citation:
Sci Rep. 2024 Feb 14;14(1):3718. doi: 10.1038/s41598-023-50677-1
Epub:
Not Epub
Abstract:
In contrast to adult mammals, zebrafish display a high capacity to heal injuries and repair damage to various organs. One of...
Delivery Method:
microinjection, injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Nys N, Khatib AM, Siegfried G. Apela promotes blood vessel regeneration and remodeling in zebrafish. Sci Rep. 2024 Feb 14;14(1):3718. doi: 10.1038/s41598-023-50677-1.

Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm

Authors:
Luu O, Barua D, Winklbauer R
Citation:
PLoS One. 2024 Feb 12;19(2):e0297420. doi: 10.1371/journal.pone.0297420. eCollection 2024
Epub:
Not Epub
Abstract:
Convergent extension of the chordamesoderm is the best-examined gastrulation movement in Xenopus. Here we study general...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Luu O, Barua D, Winklbauer R. Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm. PLoS One. 2024 Feb 12;19(2):e0297420. doi: 10.1371/journal.pone.0297420. eCollection 2024.

Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos

Authors:
Cairelli AG, Gendernalik A, Chan WX, Nguyen P, Vermot J, Lee J, Bark D Jr, Yap CH
Citation:
J Physiol. 2024 Feb 12. doi: 10.1113/JP285490. Online ahead of print
Epub:
Yes
Abstract:
Cardiac trabeculae are uneven ventricular muscular structures that develop during early embryonic heart development at the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cairelli AG, Gendernalik A, Chan WX, Nguyen P, Vermot J, Lee J, Bark D Jr, Yap CH. Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos. J Physiol. 2024 Feb 12. doi: 10.1113/JP285490. Online ahead of print.

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