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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9947 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

GABA-Induced GnRH Release Triggers Chordate Metamorphosis

Authors:
Hozumi A, Matsunobu S, Mita K, Treen N, Sugihara T, Horie T, Sakuma T, Yamamoto T, Shiraishi A, Hamada M, Satoh N, Sakurai K, Satake H, Sasakura Y
Citation:
Curr Biol. 2020;[Epub ahead of print] doi:10.1016/j.cub.2020.02.003
Abstract:
Metamorphosis, a widespread life history strategy in metazoans, allows dispersal and use of different ecological niches through...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intentinalis (ascidian)
Citation Extract:
Hozumi A, Matsunobu S, Mita K, Treen N, Sugihara T, Horie T, Sakuma T, Yamamoto T, Shiraishi A, Hamada M, Satoh N, Sakurai K, Satake H, Sasakura Y. GABA-Induced GnRH Release Triggers Chordate Metamorphosis. Curr Biol. 2020;[Epub ahead of print] doi:10.1016/j.cub.2020.02.003.

Loss of ap4s1 in zebrafish leads to neurodevelopmental defects resembling spastic paraplegia 52

Authors:
D’Amore A, Tessa A, Naef V, Bassi MT, Citterio A, Romaniello R, Fichi G, Galatolo D, Mero S, Battini R, Bertocci G, Baldacci J, Sicca F, Gemignani F, Ricca I, Rubegni A, Hirst J, Marchese M, Sahin M, Ebrahimi‐Fakhari D, Filippo M. Santorelli FM
Citation:
Ann Clin Transl Neurol. 2020;[Epub] doi:10.1002/acn3.51018
Abstract:
Autosomal recessive spastic paraplegia 52 is caused by biallelic mutations in AP4S1 which encodes a subunit of the adaptor...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
D’Amore A, Tessa A, Naef V, Bassi MT, Citterio A, Romaniello R, Fichi G, Galatolo D, Mero S, Battini R, Bertocci G, Baldacci J, Sicca F, Gemignani F, Ricca I, Rubegni A, Hirst J, Marchese M, Sahin M, Ebrahimi‐Fakhari D, Filippo M. Santorelli FM. Loss of ap4s1 in zebrafish leads to neurodevelopmental defects resembling spastic paraplegia 52. Ann Clin Transl Neurol. 2020;[Epub] doi:10.1002/acn3.51018.

Function of Arl4aa in the Initiation of Hematopoiesis in Zebrafish by Maintaining Golgi Complex Integrity in Hemogenic Endothelium

Authors:
Guo Y, Cheng BYL, Wang D, Ma ACH, He B-L, Man TK, Cheung MPL, Shi X, Ng NKL, Leung AYH
Citation:
Stem Cell Rep. 2020;[Epub ahead of print] doi:10.1016/j.stemcr.2020.02.012
Abstract:
ADP-ribosylation factor-like 4aa (Arl4aa) is a member of the ADP-ribosylation factor family. It is expressed in hematopoietic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guo Y, Cheng BYL, Wang D, Ma ACH, He B-L, Man TK, Cheung MPL, Shi X, Ng NKL, Leung AYH. Function of Arl4aa in the Initiation of Hematopoiesis in Zebrafish by Maintaining Golgi Complex Integrity in Hemogenic Endothelium. Stem Cell Rep. 2020;[Epub ahead of print] doi:10.1016/j.stemcr.2020.02.012.

De Novo Phosphoinositide Synthesis in Zebrafish Is Required for Triad Formation but Not Essential for Myogenesis

Authors:
Dowling JJ, Smith L, Fabian L, Al-Maawali A, Noche RR
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.03.24.005306
Abstract:
Phosphoinositides (PIPs) and their regulatory enzymes are key players in many cellular processes and are required for aspects...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dowling JJ, Smith L, Fabian L, Al-Maawali A, Noche RR. De Novo Phosphoinositide Synthesis in Zebrafish Is Required for Triad Formation but Not Essential for Myogenesis. bioRxiv. 2020;[preprint] doi:10.1101/2020.03.24.005306.

The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2‐deficient leukoencephalopathy

Authors:
Hamilton N, Rutherford HA, Petts JJ, Isles HM, Weber T, Henneke M, Gärtner J, Dunning M, Renshaw SA
Citation:
Glia. 2020;[Epub ahead of print] doi:10.1002/glia.23829
Abstract:
The contribution of microglia in neurological disorders is emerging as a leading disease driver rather than a consequence of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hamilton N, Rutherford HA, Petts JJ, Isles HM, Weber T, Henneke M, Gärtner J, Dunning M, Renshaw SA. The failure of microglia to digest developmental apoptotic cells contributes to the pathology of RNASET2‐deficient leukoencephalopathy. Glia. 2020;[Epub ahead of print] doi:10.1002/glia.23829.

BMP Signaling Gradient Scaling in the Zebrafish Pectoral Fin

Authors:
Mateus R, Holtzer L, Seum C, Hadjivasiliou Z, Dubois M, Jülicher F, Gonzalez-Gaitan M
Citation:
Cell Rep. 2020;30(12):4292-302.e7 doi:10.1016/j.celrep.2020.03.024
Abstract:
Secreted growth factors can act as morphogens that form spatial concentration gradients in developing organs, thereby...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mateus R, Holtzer L, Seum C, Hadjivasiliou Z, Dubois M, Jülicher F, Gonzalez-Gaitan M. BMP Signaling Gradient Scaling in the Zebrafish Pectoral Fin. Cell Rep. 2020;30(12):4292-302.e7 doi:10.1016/j.celrep.2020.03.024.

Genetic compensation in a stable slc25a46 mutant zebrafish: A case for using F0 CRISPR mutagenesis to study phenotypes caused by inherited disease

Authors:
Buglo E, Sarmiento E, Martuscelli NB, Sant DW, Danzi MC, Abrams AJ, Dallman JE, Züchner S
Citation:
PLoS ONE. 2020;15(3):e0230566. doi:10.1371/journal.pone.0230566
Abstract:
A phenomenon of genetic compensation is commonly observed when an organism with a disease-bearing mutation shows incomplete...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Buglo E, Sarmiento E, Martuscelli NB, Sant DW, Danzi MC, Abrams AJ, Dallman JE, Züchner S. Genetic compensation in a stable slc25a46 mutant zebrafish: A case for using F0 CRISPR mutagenesis to study phenotypes caused by inherited disease. PLoS ONE. 2020;15(3):e0230566. doi:10.1371/journal.pone.0230566.

Abnormal expression of GABAA receptor sub-units and hypomotility upon loss of gabra1 in zebrafish

Authors:
Reyes-Nava N, Yu HC, Coughlin CR 2nd, Shaikh TH, Quintana AM
Citation:
Biol Open. 2020 Mar 23. pii: bio.051367. doi: 10.1242/bio.051367. [Epub ahead of print]
Abstract:
We used whole exome sequencing (WES) to determine the genetic etiology of a patient with a multi-system disorder characterized...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reyes-Nava N, Yu HC, Coughlin CR 2nd, Shaikh TH, Quintana AM. Abnormal expression of GABAA receptor sub-units and hypomotility upon loss of gabra1 in zebrafish. Biol Open. 2020 Mar 23. pii: bio.051367. doi: 10.1242/bio.051367. [Epub ahead of print].

Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs

Authors:
Chan ZC-K, Kwan H-LR, Wong YS, Jiang Z, Zhou Z, Tam KW, Chan Y-S, Chan CB, Lee CW
Citation:
eLife. 2020;9:e54379 doi:10.7554/eLife.54379
Abstract:
At vertebrate neuromuscular junctions (NMJs), the synaptic basal lamina contains different extracellular matrix (ECM) proteins...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Chan ZC-K, Kwan H-LR, Wong YS, Jiang Z, Zhou Z, Tam KW, Chan Y-S, Chan CB, Lee CW. Site-directed MT1-MMP trafficking and surface insertion regulate AChR clustering and remodeling at developing NMJs. eLife. 2020;9:e54379 doi:10.7554/eLife.54379.

Prominins control ciliary length throughout the animal kingdom: New lessons from human prominin-1 and zebrafish prominin-3

Authors:
Jászai J, Thamm K, Karbanová J, Janich P, Fargeas CA, Huttner WB, Corbeil D
Citation:
J Biol Chem. 2020 Mar 22. pii: jbc.RA119.011253. doi: 10.1074/jbc.RA119.011253. [Epub ahead of print]
Abstract:
Prominins (proms) are transmembrane glycoproteins conserved throughout the animal kingdom. They are associated with plasma...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jászai J, Thamm K, Karbanová J, Janich P, Fargeas CA, Huttner WB, Corbeil D. Prominins control ciliary length throughout the animal kingdom: New lessons from human prominin-1 and zebrafish prominin-3. J Biol Chem. 2020 Mar 22. pii: jbc.RA119.011253. doi: 10.1074/jbc.RA119.011253. [Epub ahead of print].

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