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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11657 scientific papers returned from the database with the search filters currently being used below.

Unraveling Presenilin 2 Functions in a Knockout Zebrafish Line to Shed Light into Alzheimer’s Disease Pathogenesis

Authors:
Barazzuol L, Cieri D, Facchinello N, Calì T, Washbourne P, Argenton F, Pizzo P
Citation:
Cells. 2023;12(3):376. doi:10.3390/cells12030376
Epub:
Not Epub
Abstract:
Mutations in presenilin 2 (PS2) have been causally linked to the development of inherited Alzheimer’s disease (AD). Besides its...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Barazzuol L, Cieri D, Facchinello N, Calì T, Washbourne P, Argenton F, Pizzo P. Unraveling Presenilin 2 Functions in a Knockout Zebrafish Line to Shed Light into Alzheimer’s Disease Pathogenesis. Cells. 2023;12(3):376. doi:10.3390/cells12030376.

SMIM36, a novel and conserved microprotein, is involved in retinal lamination in zebrafish

Authors:
Sharma S, Ramasamy S, Khan Y, Joshi DC, Pillai B
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.01.14.524032
Epub:
Not Epub
Abstract:
Microproteins are small proteins comprising 2 to 200 amino acids, arising from small Open Reading Frames (smORFs). They are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma S, Ramasamy S, Khan Y, Joshi DC, Pillai B. SMIM36, a novel and conserved microprotein, is involved in retinal lamination in zebrafish. bioRxiv. 2023;[preprint] doi:10.1101/2023.01.14.524032.

Multiple pkd and piezo gene family members are required for atrioventricular valve formation

Authors:
Juan T, Ribeiro da Silva A, Cardoso B, Lim SE, Charteau V, Stainier DYR
Citation:
Nat Commun. 2023;14(1):214. doi:10.1038/s41467-023-35843-3
Epub:
Not Epub
Abstract:
Cardiac valves ensure unidirectional blood flow through the heart, and altering their function can result in heart failure....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Juan T, Ribeiro da Silva A, Cardoso B, Lim SE, Charteau V, Stainier DYR. Multiple pkd and piezo gene family members are required for atrioventricular valve formation. Nat Commun. 2023;14(1):214. doi:10.1038/s41467-023-35843-3.

Identification of the Time Period during Which BMP Signaling Regulates Proliferation of Neural Progenitor Cells in Zebrafish

Authors:
Shih H-Y, Chang C-W, Chen Y-C, Cheng Y-C
Citation:
Int J Mol Sci. 2023;24(2):1733. doi:10.3390/ijms24021733
Epub:
Not Epub
Abstract:
Bone morphogenetic protein (BMP) signaling regulates neural induction, neuronal specification, and neuronal differentiation....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shih H-Y, Chang C-W, Chen Y-C, Cheng Y-C. Identification of the Time Period during Which BMP Signaling Regulates Proliferation of Neural Progenitor Cells in Zebrafish. Int J Mol Sci. 2023;24(2):1733. doi:10.3390/ijms24021733 .

Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis

Authors:
Petrillo S, De Giorgio F, Bertino F, Garello F, Bitonto V, Longo DL, Mercurio S, Ammirata G, Allocco AL, Fiorito V, Chiabrando D, Altruda F, Terreno E, Provero P, Munaron L, Genova T, Nóvoa A, Carlos AR, Cardoso S, Mallo M, Soares MP, Tolosano E
Citation:
Angiogenesis. 2023 Jan 11. doi: 10.1007/s10456-023-09865-w. Online ahead of print
Epub:
Not Epub
Abstract:
The Feline Leukemia Virus Subgroup C Receptor 1a (FLVCR1a) is a transmembrane heme exporter essential for embryonic vascular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Petrillo S, De Giorgio F, Bertino F, Garello F, Bitonto V, Longo DL, Mercurio S, Ammirata G, Allocco AL, Fiorito V, Chiabrando D, Altruda F, Terreno E, Provero P, Munaron L, Genova T, Nóvoa A, Carlos AR, Cardoso S, Mallo M, Soares MP, Tolosano E. Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis. Angiogenesis. 2023 Jan 11. doi: 10.1007/s10456-023-09865-w. Online ahead of print.

Inducible in vivo genome editing in the sea star Patiria miniata

Authors:
Zueva O, Hinman VF
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.01.09.523328
Epub:
Not Epub
Abstract:
For centuries, echinoderms, a marine-invertebrate phylum, have fascinated scientists for their developmental and postembryonic...
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Zueva O, Hinman VF. Inducible in vivo genome editing in the sea star Patiria miniata. bioRxiv. 2023;[preprint] doi:10.1101/2023.01.09.523328.

Channel Function of Polycystin-2 in the Endoplasmic Reticulum Protects against Autosomal Dominant Polycystic Kidney Disease

Authors:
Padhy B, Xie J, Wang R, Lin F, Huang CL
Citation:
J Am Soc Nephrol. 2022 Aug;33(8):1501-1516. doi: 10.1681/ASN.2022010053. Epub 2022 Jul 14
Epub:
Not Epub
Abstract:
Background: Mutations of PKD2, which encodes polycystin-2, cause autosomal dominant polycystic kidney disease (ADPKD). The...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Padhy B, Xie J, Wang R, Lin F, Huang CL. Channel Function of Polycystin-2 in the Endoplasmic Reticulum Protects against Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol. 2022 Aug;33(8):1501-1516. doi: 10.1681/ASN.2022010053. Epub 2022 Jul 14.

Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development

Authors:
Christodoulou N, Skourides PA
Citation:
Front Cell Dev Biol. 2023;10:1091629. doi:10.3389/fcell.2022.1091629
Epub:
Not Epub
Abstract:
Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Christodoulou N, Skourides PA. Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development. Front Cell Dev Biol. 2023;10:1091629. doi:10.3389/fcell.2022.1091629.

Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs

Authors:
Das MR, Chang Y, Anderson R, Saunders RA, Zhang N, Tomberlin CP, Vale RD, Jain A
Citation:
Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2215071120. doi: 10.1073/pnas.2215071120. Epub 2023 Jan 9
Epub:
Not Epub
Abstract:
CAG trinucleotide repeat expansions cause several neurodegenerative diseases, including Huntington's disease and...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: U-2OS cells (ATCC, HTB-96)
Citation Extract:
Das MR, Chang Y, Anderson R, Saunders RA, Zhang N, Tomberlin CP, Vale RD, Jain A. Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2215071120. doi: 10.1073/pnas.2215071120. Epub 2023 Jan 9.

Hydrozoan sperm-specific SPKK motif-containing histone H2B variants stabilise chromatin with limited compaction

Authors:
Török A, Browne MJG, Vilar JC, Patwal I, DuBuc TQ, Febrimarsa, Atcheson E, Frank U, Gornik SG, Flaus A
Citation:
Development. 2023 Jan 1;150(1):dev201058. doi: 10.1242/dev.201058. Epub 2023 Jan 12
Epub:
Not Epub
Abstract:
Many animals achieve sperm chromatin compaction and stabilisation by replacing canonical histones with sperm nuclear basic...
Delivery Method:
microinjection
Organism or Cell Type:
Hydractinia symbiolongicarpus (cnidarian)
Citation Extract:
Török A, Browne MJG, Vilar JC, Patwal I, DuBuc TQ, Febrimarsa, Atcheson E, Frank U, Gornik SG, Flaus A. Hydrozoan sperm-specific SPKK motif-containing histone H2B variants stabilise chromatin with limited compaction. Development. 2023 Jan 1;150(1):dev201058. doi: 10.1242/dev.201058. Epub 2023 Jan 12.

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