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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12299 scientific papers returned from the database with the search filters currently being used below.

Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel-Like Structures in Hydrogels for Tissue Engineering

Authors:
Patra C, Rayrikar A, Wagh G, Kleefeldt F, Roshanbinfar K, Cop F, Nikolic I, Schmidt MHH, Acker-Palmer A, Ergün S, Engel FB
Citation:
J Am Heart Assoc. 2025 Jan 23:e037943. doi: 10.1161/JAHA.123.037943. Epub ahead of print. PMID: 39846290
Epub:
Not Epub
Abstract:
Background: Organs and tissues need to be vascularized during development. Similarly, vascularization is required to engineer...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patra C, Rayrikar A, Wagh G, Kleefeldt F, Roshanbinfar K, Cop F, Nikolic I, Schmidt MHH, Acker-Palmer A, Ergün S, Engel FB. Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel-Like Structures in Hydrogels for Tissue Engineering. J Am Heart Assoc. 2025 Jan 23:e037943. doi: 10.1161/JAHA.123.037943. Epub ahead of print. PMID: 39846290.

Dual role of Xenopus Odf2 in multiciliated cell patterning and differentiation

Authors:
Nommick A, Chuyen A, Clément R, Thomé V, Daian F, Rosnet O, Richard F, Brouilly N, Loiseau E, Boutin C, Kodjabachian L
Citation:
Dev Biol. 2025 Jan 24:S0012-1606(25)00026-0. doi: 10.1016/j.ydbio.2025.01.014. Epub ahead of print. PMID: 39864486
Epub:
Not Epub
Abstract:
In developing tissues, the number, position, and differentiation of cells must be coordinately controlled to ensure the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nommick A, Chuyen A, Clément R, Thomé V, Daian F, Rosnet O, Richard F, Brouilly N, Loiseau E, Boutin C, Kodjabachian L. Dual role of Xenopus Odf2 in multiciliated cell patterning and differentiation. Dev Biol. 2025 Jan 24:S0012-1606(25)00026-0. doi: 10.1016/j.ydbio.2025.01.014. Epub ahead of print. PMID: 39864486.

Zebrafish PEX1 Is Required for the Generation of GABAergic Neuron in p3 Domain

Authors:
Ryu JH, Kim M, Kim A, Ro H, Kim SH, Yeo SY
Citation:
Dev Reprod. 2024 Dec;28(4):129-139. doi: 10.12717/DR.2024.28.4.129. Epub 2024 Dec 31. PMID: 39845513; PMCID: PMC11750165
Epub:
Not Epub
Abstract:
Maintenance of neural progenitors requires Notch signaling in vertebrate development. Previous study has shown that Jagged2-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ryu JH, Kim M, Kim A, Ro H, Kim SH, Yeo SY. Zebrafish PEX1 Is Required for the Generation of GABAergic Neuron in p3 Domain. Dev Reprod. 2024 Dec;28(4):129-139. doi: 10.12717/DR.2024.28.4.129. Epub 2024 Dec 31. PMID: 39845513; PMCID: PMC11750165.

Hypusinated and unhypusinated isoforms of the translation factor eIF5A exert distinct effects in models of pancreas development and function

Authors:
Anderson CM, Kulkarni A, Maier B, Huang F, Figatner K, Chakraborty A, Pratuangtham S, May SC, Tersey SA, Anderson RM, Mirmira RG
Citation:
J Biol Chem. 2025 Jan 18:108209. doi: 10.1016/j.jbc.2025.108209. Epub ahead of print. PMID: 39832654
Epub:
Not Epub
Abstract:
Hypusination of eukaryotic translation initiation factor 5A (eIF5A) is essential for its role in translation elongation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Anderson CM, Kulkarni A, Maier B, Huang F, Figatner K, Chakraborty A, Pratuangtham S, May SC, Tersey SA, Anderson RM, Mirmira RG. Hypusinated and unhypusinated isoforms of the translation factor eIF5A exert distinct effects in models of pancreas development and function. J Biol Chem. 2025 Jan 18:108209. doi: 10.1016/j.jbc.2025.108209. Epub ahead of print. PMID: 39832654.

A Lateral Line Specific Mucin Involved in Cupula Growth and Vibration Detection in Zebrafish

Authors:
Ma Z, Tian Y, Wang Y, Wang C, Wang J, Fan C
Citation:
Int J Mol Sci. 2025 Jan 15;26(2):708. doi: 10.3390/ijms26020708. PMID: 39859421; PMCID: PMC11765562
Epub:
Not Epub
Abstract:
The lateral line system in fish is crucial for detecting water flow, which facilitates various behaviors such as prey detection...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma Z, Tian Y, Wang Y, Wang C, Wang J, Fan C. A Lateral Line Specific Mucin Involved in Cupula Growth and Vibration Detection in Zebrafish. Int J Mol Sci. 2025 Jan 15;26(2):708. doi: 10.3390/ijms26020708. PMID: 39859421; PMCID: PMC11765562.

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T-tubule pH regulation

Authors:
Neitzel LR, Silver M, Wasserman AH, Rea S, Hong CC, Williams CH
Citation:
Dev Dyn. 2025 Jan 22. doi: 10.1002/dvdy.770. Epub ahead of print. PMID: 39840753
Epub:
Not Epub
Abstract:
Disruption of extracellular pH and proton-sensing can profoundly impact cellular and protein functions, leading to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Neitzel LR, Silver M, Wasserman AH, Rea S, Hong CC, Williams CH. A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T-tubule pH regulation. Dev Dyn. 2025 Jan 22. doi: 10.1002/dvdy.770. Epub ahead of print. PMID: 39840753.

Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance

Authors:
Widziolek M, Mieszkowska A, Marcinkowska M, Salamaga B, Folkert J, Rakus K, Chadzinska M, Potempa J, Stafford GP, Prajsnar TK, Murdoch C
Citation:
PLoS Pathog. 2025 Jan 21;21(1):e1012821. doi: 10.1371/journal.ppat.1012821. Epub ahead of print. PMID: 39836688
Epub:
Not Epub
Abstract:
Porphyromonas gingivalis (Pg) is a keystone pathogen in periodontitis, a highly prevalent disease manifested by chronic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Widziolek M, Mieszkowska A, Marcinkowska M, Salamaga B, Folkert J, Rakus K, Chadzinska M, Potempa J, Stafford GP, Prajsnar TK, Murdoch C. Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance. PLoS Pathog. 2025 Jan 21;21(1):e1012821. doi: 10.1371/journal.ppat.1012821. Epub ahead of print. PMID: 39836688.

Secreted Frizzled-Related Protein 1a regulates hematopoietic development in a dose-dependent manner

Authors:
Ide AD, Carpenter KA, Elaswad M, Opria K, Marcellin K, Gilliland C, Grainger S
Citation:
bioRxiv 2025.01.10.632371; doi: https://doi.org/10.1101/2025.01.10.632371
Epub:
Not Epub
Abstract:
Hematopoietic stem and progenitor cells (HSPCs) arise only during embryonic development, and their identity specification,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ide AD, Carpenter KA, Elaswad M, Opria K, Marcellin K, Gilliland C, Grainger S. Secreted Frizzled-Related Protein 1a regulates hematopoietic development in a dose-dependent manner. bioRxiv 2025.01.10.632371; doi: https://doi.org/10.1101/2025.01.10.632371.

Antisense mediated blockade of Dickkopf 1 attenuates tumor survival, metastases and bone damage in experimental osteosarcoma

Authors:
Haskell A, Pan S, Reese R, Powers A, Lopez MG, Lomeli S, Story C, Benton J, Blazier JC, Kaunas R, Gregory CA
Citation:
Sci Rep. 2025 Jan 13;15(1):1878. doi: 10.1038/s41598-024-84037-4. PMID: 39805917
Epub:
Not Epub
Abstract:
Osteosarcoma (OS) is the most common primary bone malignancy. The canonical Wnt inhibitor Dickkopf-1 (Dkk-1) has been...
Delivery Method:
Vivo-Morpholino; intraperitoneal (i.p.) injection for mice
Organism or Cell Type:
cells: Dkk-1 expressing MOSJ cells, OEhMSCs and MG63 3D co-cultures; mice: DAR human PDX-OS xenograft NSG mouse model
Citation Extract:
Haskell A, Pan S, Reese R, Powers A, Lopez MG, Lomeli S, Story C, Benton J, Blazier JC, Kaunas R, Gregory CA. Antisense mediated blockade of Dickkopf 1 attenuates tumor survival, metastases and bone damage in experimental osteosarcoma. Sci Rep. 2025 Jan 13;15(1):1878. doi: 10.1038/s41598-024-84037-4. PMID: 39805917.

Sex determination factor, a novel male-linked gene in the sea cucumber Apostichopus japonicus: Molecular characterization, expression patterns and effects of gene knockdown

Authors:
Meng W, Kong L, Abulizi A, Cong J, Sun Z, Chang Y
Citation:
Comp Biochem Physiol B Biochem Mol Biol. 2025 Jan 6;277:111071. doi: 10.1016/j.cbpb.2025.111071. Epub ahead of print. PMID: 39778676
Epub:
Not Epub
Abstract:
Apostichopus japonicus is a highly significant marine aquaculture species. Research findings have indicated that male sea...
Delivery Method:
Vivo-Morpholino bathing
Organism or Cell Type:
Apostichopus japonicus (sea cucumber)
Citation Extract:
Meng W, Kong L, Abulizi A, Cong J, Sun Z, Chang Y. Sex determination factor, a novel male-linked gene in the sea cucumber Apostichopus japonicus: Molecular characterization, expression patterns and effects of gene knockdown. Comp Biochem Physiol B Biochem Mol Biol. 2025 Jan 6;277:111071. doi: 10.1016/j.cbpb.2025.111071. Epub ahead of print. PMID: 39778676.

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