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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11485 scientific papers returned from the database with the search filters currently being used below.

Single nuclei transcriptomics of muscle reveals intra-muscular cell dynamics linked to dystrophin loss and rescue

Authors:
Scripture-Adams DD, Chesmore KN, Barthélémy F, Wang RT, Nieves-Rodriguez S, Wang DW, Mokhonova EI, Douine ED, Wan J, Little I, Rabichow LN, Nelson SF, Miceli MC
Citation:
Commun Biol 5, 989 (2022). https://doi.org/10.1038/s42003-022-03938-0
Epub:
Not Epub
Abstract:
In Duchenne muscular dystrophy, dystrophin loss leads to chronic muscle damage, dysregulation of repair, fibro-fatty...
Organism or Cell Type:
mice, human
Citation Extract:
Scripture-Adams DD, Chesmore KN, Barthélémy F, Wang RT, Nieves-Rodriguez S, Wang DW, Mokhonova EI, Douine ED, Wan J, Little I, Rabichow LN, Nelson SF, Miceli MC. Single nuclei transcriptomics of muscle reveals intra-muscular cell dynamics linked to dystrophin loss and rescue. Commun Biol 5, 989 (2022). https://doi.org/10.1038/s42003-022-03938-0.

De novo disruptive heterozygous MMP21 variants are potential predisposing genetic risk factors in Chinese Han heterotaxy children

Authors:
Qin X-j, Xu M-m, Ye J-j, Niu Y-w, Wu Y-r, Xu R, Li F, Fu Q-h, Chen S, Sun K, Xu Y-j
Citation:
Hum Genomics. 2022;16:41. doi:10.1186/s40246-022-00409-9
Epub:
Not Epub
Abstract:
Background: Heterotaxy syndrome (HTX) is caused by aberrant left-right patterning early in embryonic development, which results...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Qin X-j, Xu M-m, Ye J-j, Niu Y-w, Wu Y-r, Xu R, Li F, Fu Q-h, Chen S, Sun K, Xu Y-j. De novo disruptive heterozygous MMP21 variants are potential predisposing genetic risk factors in Chinese Han heterotaxy children. Hum Genomics. 2022;16:41. doi:10.1186/s40246-022-00409-9.

RIOK3 and Its Alternatively Spliced Isoform Have Disparate Roles in the Innate Immune Response to Rift Valley Fever Virus (MP12) Infection

Authors:
Bisom TC, White LA, Lanchy J-M, Lodmell JS
Citation:
Viruses. 2022;14(9):2064. doi:10.3390/v14092064
Epub:
Not Epub
Abstract:
Rift Valley fever virus (RVFV) is a pathogenic human and livestock RNA virus that poses a significant threat to public health...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK 293
Citation Extract:
Bisom TC, White LA, Lanchy J-M, Lodmell JS. RIOK3 and Its Alternatively Spliced Isoform Have Disparate Roles in the Innate Immune Response to Rift Valley Fever Virus (MP12) Infection. Viruses. 2022;14(9):2064. doi:10.3390/v14092064 .

Hybridization led to a rewired pluripotency network in the allotetraploid Xenopus laevis

Authors:
Phelps WA, Hurton MD, Ayers TN, Carlson AE, Rosenbaum JC, Lee MT
Citation:
bioRxiv. 2022;[preprint] doi:10.1101/2022.09.14.507817
Epub:
Not Epub
Abstract:
After fertilization, maternally contributed factors to the egg initiate the transition to pluripotency to give rise to...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Phelps WA, Hurton MD, Ayers TN, Carlson AE, Rosenbaum JC, Lee MT. Hybridization led to a rewired pluripotency network in the allotetraploid Xenopus laevis. bioRxiv. 2022;[preprint] doi:10.1101/2022.09.14.507817.

Involvement of transmembrane protein 184a during angiogenesis in zebrafish embryos

Authors:
Field CJ, Perez AM, Samet T, Ricles V, Iovine MK, Lowe-Krentz LJ
Citation:
Front Physiol. 2022 Sep 2;13:845407. doi: 10.3389/fphys.2022.845407. eCollection 2022
Epub:
Not Epub
Abstract:
Angiogenesis, the outgrowth of new blood vessels from existing vasculature, is critical during development, tissue formation,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Field CJ, Perez AM, Samet T, Ricles V, Iovine MK, Lowe-Krentz LJ. Involvement of transmembrane protein 184a during angiogenesis in zebrafish embryos. Front Physiol. 2022 Sep 2;13:845407. doi: 10.3389/fphys.2022.845407. eCollection 2022.

Functional characterization of a novel TP53RK mutation identified in a family with Galloway-Mowat syndrome

Authors:
Treimer E, Kalayci T, Schumann S, Suer I, Greco S, Schanze D, Schmeisser MJ, Kühl SJ, Zenker M
Citation:
Hum Mutat. 2022 Sep 18. doi: 10.1002/humu.24472. Online ahead of print.
Epub:
Not Epub
Abstract:
Galloway-Mowat syndrome (GAMOS) is a very rare condition characterized by early-onset nephrotic syndrome and microcephaly with...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Treimer E, Kalayci T, Schumann S, Suer I, Greco S, Schanze D, Schmeisser MJ, Kühl SJ, Zenker M. Functional characterization of a novel TP53RK mutation identified in a family with Galloway-Mowat syndrome. Hum Mutat. 2022 Sep 18. doi: 10.1002/humu.24472. Online ahead of print..

Zinc transporter Slc30a1 regulates melanocyte development by interacting with mt2 in zebrafish

Authors:
Xia Z, Yang X, Bi X, Tong X, Min J, Wang F
Citation:
Eur J Cell Biol. 2022;101(4):151272. doi:10.1016/j.ejcb.2022.151272
Epub:
Not Epub
Abstract:
The essential trace element zinc is involved in multiple biological processes including development and metabolism, while its...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xia Z, Yang X, Bi X, Tong X, Min J, Wang F. Zinc transporter Slc30a1 regulates melanocyte development by interacting with mt2 in zebrafish. Eur J Cell Biol. 2022;101(4):151272. doi:10.1016/j.ejcb.2022.151272.

Evaluation of phages and liposomes as combination therapy to counteract Pseudomonas aeruginosa infection in wild-type and CFTR-null models

Authors:
Cafora M, Poerio N, Forti F, Loberto N, Pin D, Bassi R, Aureli M, Briani F, Pistocchi A, Fraziano M
Citation:
Front Microbiol. 2022;13:979610. doi:10.3389/fmicb.2022.979610
Epub:
Not Epub
Abstract:
Multi drug resistant (MDR) bacteria are insensitive to the most common antibiotics currently in use. The spread of antibiotic-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cafora M, Poerio N, Forti F, Loberto N, Pin D, Bassi R, Aureli M, Briani F, Pistocchi A, Fraziano M. Evaluation of phages and liposomes as combination therapy to counteract Pseudomonas aeruginosa infection in wild-type and CFTR-null models. Front Microbiol. 2022;13:979610. doi:10.3389/fmicb.2022.979610.

A self-generated Toddler gradient guides mesodermal cell migration

Authors:
Stock J, Kazmar T, Schlumm F, Hannezo E, Pauli A
Citation:
Sci Adv. 2022 Sep 16;8(37):eadd2488. doi: 10.1126/sciadv.add2488. Epub 2022 Sep 14
Epub:
Not Epub
Abstract:
The sculpting of germ layers during gastrulation relies on the coordinated migration of progenitor cells, yet the cues...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stock J, Kazmar T, Schlumm F, Hannezo E, Pauli A. A self-generated Toddler gradient guides mesodermal cell migration. Sci Adv. 2022 Sep 16;8(37):eadd2488. doi: 10.1126/sciadv.add2488. Epub 2022 Sep 14.

Effects of pharmacological and genetic manipulation of glucocorticoids during early development of the zebrafish embryo

Authors:
Wilson K, Matrone G, Tucker C, Hadoke P, Kenyon C, Mullins J, Denvir M
Citation:
Endocrine Abstracts. 2013;32:P336 doi:10.1530/endoabs.32.P336
Epub:
Not Epub
Abstract:
Background: The effects of glucocorticoids (GC) on the developing zebrafish embryo (Zfe) are poorly characterised. We have...
Organism or Cell Type:
zebrafish
Citation Extract:
Wilson K, Matrone G, Tucker C, Hadoke P, Kenyon C, Mullins J, Denvir M. Effects of pharmacological and genetic manipulation of glucocorticoids during early development of the zebrafish embryo. Endocrine Abstracts. 2013;32:P336 doi:10.1530/endoabs.32.P336.

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