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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10536 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

The tight junction protein Claudin-5 limits endothelial cell motility

Authors:
Yang Z, Wu S, Fontana F, Li Y, Xiao W, Gao Z, Krudewig A, Affolter M, Belting H-G, Abdelilah-Seyfried S, Zhang J
Citation:
J Cell Sci. 2021;134:jcs248237 doi:10.1242/jcs.248237
Abstract:
Steinberg's differential adhesion hypothesis suggests that adhesive mechanisms are important for sorting of cells and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Z, Wu S, Fontana F, Li Y, Xiao W, Gao Z, Krudewig A, Affolter M, Belting H-G, Abdelilah-Seyfried S, Zhang J. The tight junction protein Claudin-5 limits endothelial cell motility. J Cell Sci. 2021;134:jcs248237 doi:10.1242/jcs.248237.

Use of a carbonic anhydrase Ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio)

Authors:
Zimmer AM, Mandic M, Yew HM, Kunert E, Pan YK, Ha J, Kwong RWM, Gilmour KM, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2021;320(1):R55-R68. doi:10.1152/ajpregu.00215.2020
Abstract:
In fishes, branchial cytosolic carbonic anhydrase (CA) plays an important role in ion and acid-base regulation. The Ca17a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zimmer AM, Mandic M, Yew HM, Kunert E, Pan YK, Ha J, Kwong RWM, Gilmour KM, Perry SF. Use of a carbonic anhydrase Ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2021;320(1):R55-R68. doi:10.1152/ajpregu.00215.2020.

Venous Thrombosis and Thrombocyte Activity in Zebrafish Models of Quantitative and Qualitative Fibrinogen Disorders

Authors:
Fish RJ, Freire C, Di Sanza C, Neerman-Arbez M
Citation:
Int J Molec Sci. 2021;22(2):1422-0067 doi:10.3390/ijms22020655
Abstract:
Venous thrombosis occurs in patients with quantitative and qualitative fibrinogen disorders. Injury-induced thrombosis in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fish RJ, Freire C, Di Sanza C, Neerman-Arbez M. Venous Thrombosis and Thrombocyte Activity in Zebrafish Models of Quantitative and Qualitative Fibrinogen Disorders. Int J Molec Sci. 2021;22(2):1422-0067 doi:10.3390/ijms22020655.

The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos

Authors:
Mignani L, Zizioli D, Borsani G, Monti E, Finazzi D
Citation:
Front Cell Dev Biol. 2020 Dec 23;8:596069. doi: 10.3389/fcell.2020.596069. eCollection 2020
Abstract:
Mitochondrial membrane Protein Associated Neurodegeneration (MPAN) is a rare genetic disorder due to mutations in C19orf12 gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mignani L, Zizioli D, Borsani G, Monti E, Finazzi D. The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos. Front Cell Dev Biol. 2020 Dec 23;8:596069. doi: 10.3389/fcell.2020.596069. eCollection 2020.

Yulink, predicted from evolutionary analysis, is involved in cardiac function

Authors:
Kuo MW, Tsai HH, Wang SH, Chen YY, Yu AL, Yu J
Citation:
J Biomed Sci. 2021 Jan 11;28(1):7. doi: 10.1186/s12929-020-00701-7
Abstract:
Background: The comparative evolutionary genomics analysis was used to study the functions of novel Ka/Ks-predicted human exons...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kuo MW, Tsai HH, Wang SH, Chen YY, Yu AL, Yu J. Yulink, predicted from evolutionary analysis, is involved in cardiac function. J Biomed Sci. 2021 Jan 11;28(1):7. doi: 10.1186/s12929-020-00701-7.

NF-Y is critical for the proper growth of zebrafish embryonic heart and its cardiomyocyte proliferation

Authors:
Chen J
Citation:
Genesis. 2021 Jan 8:e23408. doi: 10.1002/dvg.23408. Online ahead of print
Abstract:
The ubiquitous NF-Y gene regulates the expression of different genes in various signaling pathways. However, the function of NF...
Organism or Cell Type:
zebrafish
Citation Extract:
Chen J. NF-Y is critical for the proper growth of zebrafish embryonic heart and its cardiomyocyte proliferation. Genesis. 2021 Jan 8:e23408. doi: 10.1002/dvg.23408. Online ahead of print.

A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord

Authors:
Tsata V, Möllmert S, Schweitzer C, Kolb J, Möckel C, Böhm B, Rosso G, Lange C, Lesche M, Hammer J, Kesavan G, Beis D, Guck J, Brand M, Wehner D
Citation:
Dev Cell. 2021;[Epub ahead of print] doi:10.1016/j.devcel.2020.12.009
Abstract:
In mammals, perivascular cell-derived scarring after spinal cord injury impedes axonal regrowth. In contrast, the extracellular...
Delivery Method:
Vivo-Morpholino pericardial vein injection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsata V, Möllmert S, Schweitzer C, Kolb J, Möckel C, Böhm B, Rosso G, Lange C, Lesche M, Hammer J, Kesavan G, Beis D, Guck J, Brand M, Wehner D. A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord. Dev Cell. 2021;[Epub ahead of print] doi:10.1016/j.devcel.2020.12.009.

Ectoderm to mesoderm transition by down-regulation of actomyosin contractility

Authors:
Kashkooli L, Rozema D, Espejo-Ramirez L, Lasko P, Fagotto F
Citation:
PLoS Biol. 2021;19(1):e3001060. doi:10.1371/journal.pbio.3001060
Abstract:
Collective migration of cohesive tissues is a fundamental process in morphogenesis and is particularly well illustrated during...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kashkooli L, Rozema D, Espejo-Ramirez L, Lasko P, Fagotto F. Ectoderm to mesoderm transition by down-regulation of actomyosin contractility. PLoS Biol. 2021;19(1):e3001060. doi:10.1371/journal.pbio.3001060.

The administration of antisense oligonucleotide golodirsen reduces pathological regeneration in patients with Duchenne muscular dystrophy

Authors:
Scaglioni D, Catapano F, Ellis M, Torelli S, Chambers D, Feng L, Beck M, Sewry C, Monforte M, Harriman S, Koenig E, Malhotra J, Popplewell L, Guglieri M, Straub V, Mercuri E, Servais L, Phadke R, Morgan J, Muntoni F
Citation:
Acta Neuropathol Commun. 2021 Jan 6;9(1):7. doi: 10.1186/s40478-020-01106-1
Abstract:
During the last decade, multiple clinical trials for Duchenne muscular dystrophy (DMD) have focused on the induction of...
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Scaglioni D, Catapano F, Ellis M, Torelli S, Chambers D, Feng L, Beck M, Sewry C, Monforte M, Harriman S, Koenig E, Malhotra J, Popplewell L, Guglieri M, Straub V, Mercuri E, Servais L, Phadke R, Morgan J, Muntoni F. The administration of antisense oligonucleotide golodirsen reduces pathological regeneration in patients with Duchenne muscular dystrophy. Acta Neuropathol Commun. 2021 Jan 6;9(1):7. doi: 10.1186/s40478-020-01106-1.

Leucyl-tRNA Synthetase Deficiency Systemically Induces Excessive Autophagy in Zebrafish

Authors:
Shiraishi H, Shimizu N, Tsumori M, Kiyota K, Maeda M, Ishitani T, Hanada R, Ihara K, Hanada T, Inoue M, Miyahara H
Citation:
Research Square. 2021;[preprint] doi:10.21203/rs.3.rs-132893/v1
Abstract:
Leucyl-tRNA synthetase (LARS) is an enzyme that catalyses the ligation of leucine with leucine tRNA. LARS is also essential to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shiraishi H, Shimizu N, Tsumori M, Kiyota K, Maeda M, Ishitani T, Hanada R, Ihara K, Hanada T, Inoue M, Miyahara H. Leucyl-tRNA Synthetase Deficiency Systemically Induces Excessive Autophagy in Zebrafish. Research Square. 2021;[preprint] doi:10.21203/rs.3.rs-132893/v1.

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