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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9646 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Neuroblast sensory quiescence depends of vascular cytoneme contacts and sensory neuronal differentiation requires initiation of blood flow

Authors:
Taberner L, Bañón A, Alsina B
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/667519
Abstract:
In many organs, stem cell function depends on the communication with their niche partners. Cranial sensory neurons develop in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taberner L, Bañón A, Alsina B. Neuroblast sensory quiescence depends of vascular cytoneme contacts and sensory neuronal differentiation requires initiation of blood flow. bioRxiv. 2019;[preprint] doi:10.1101/667519 .

Hingepoints and neural folds reveal conserved features of primary neurulation in the zebrafish forebrain

Authors:
Werner JM, Negesse MY, Brooks DL, Caldwell AR, Johnson JM, Brewster R
Citation:
bioRxiv. 2019;[preprint] doi:/10.1101/738161
Abstract:
Primary neurulation is the process by which the neural tube, the central nervous system precursor, is formed from the neural...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Werner JM, Negesse MY, Brooks DL, Caldwell AR, Johnson JM, Brewster R. Hingepoints and neural folds reveal conserved features of primary neurulation in the zebrafish forebrain. bioRxiv. 2019;[preprint] doi:/10.1101/738161 .

Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles

Authors:
Kuhn J, Klein PM, Al Danaf N, Nordin JZ, Reinhard S, Loy DM, Höhn M, El Andaloussi S, Lamb DC, Wagner E, Aoki Y, Lehto T, Lächelt U
Citation:
Adv Funct Mater. 2019;[Epub] doi:10.1002/adfm.201906432
Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) are oligonucleotide analogs that can be used for therapeutic modulation of pre‐...
Delivery Method:
nanoparticle
Organism or Cell Type:
cell culture: HeLa pLuc/705, mdx52 skeletal myotubes
Citation Extract:
Kuhn J, Klein PM, Al Danaf N, Nordin JZ, Reinhard S, Loy DM, Höhn M, El Andaloussi S, Lamb DC, Wagner E, Aoki Y, Lehto T, Lächelt U. Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles. Adv Funct Mater. 2019;[Epub] doi:10.1002/adfm.201906432.

Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals

Authors:
Gentsch GE, Spruce T, Owens NDL, Smith JC
Citation:
Nat Comm. 2019;10(1):4269. doi:10.1038/s41467-019-12263-w
Abstract:
Embryonic development yields many different cell types in response to just a few families of inductive signals. The property of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gentsch GE, Spruce T, Owens NDL, Smith JC. Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals. Nat Comm. 2019;10(1):4269. doi:10.1038/s41467-019-12263-w.

Loss of Nance-Horan Syndrome b (nhsb) prevents expansion growth of retinal progenitor cells by selective up-regulation of Δ113p53

Authors:
Vorster PJ, Ojumu J, Dickinson AJG, Walsh GS
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/775171
Abstract:
The regulation of cell cycle progression and differentiation in retinal progenitor cells is a fundamental feature controlling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish, Xenopus tropicalis
Citation Extract:
Vorster PJ, Ojumu J, Dickinson AJG, Walsh GS. Loss of Nance-Horan Syndrome b (nhsb) prevents expansion growth of retinal progenitor cells by selective up-regulation of Δ113p53. bioRxiv. 2019;[preprint] doi:10.1101/775171 .

The investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish

Authors:
Kim HR, Santhakumar K, Markham E, Baldera D, Bryant HE, El-Khamisy SF, van Eeden FJM
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/767459
Abstract:
pVHL is a tumor suppressor. The lack of its function leads to various tumors, among which ccRCC (clear cell renal cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim HR, Santhakumar K, Markham E, Baldera D, Bryant HE, El-Khamisy SF, van Eeden FJM. The investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish. bioRxiv. 2019;[preprint] doi:10.1101/767459.

Rgma-induced Neo1 proteolysis promotes neural tube morphogenesis

Authors:
Brown S, Jayachandran P, Negesse M, Olmo V, Vital E, Brewster R
Citation:
J Neurosci. 2019 Aug 9. pii: 3262-18. doi: 10.1523/JNEUROSCI.3262-18.2019. [Epub ahead of print]
Abstract:
Neuroepithelial cell (NEC) elongation is one of several key cell behaviors that mediate the tissue-level morphogenetic...
Organism or Cell Type:
zebrafish
Citation Extract:
Brown S, Jayachandran P, Negesse M, Olmo V, Vital E, Brewster R. Rgma-induced Neo1 proteolysis promotes neural tube morphogenesis. J Neurosci. 2019 Aug 9. pii: 3262-18. doi: 10.1523/JNEUROSCI.3262-18.2019. [Epub ahead of print].

The evolution of a new cell type was associated with competition for a signaling ligand

Authors:
Ettensohn CA, Adomako-Ankomah A
Citation:
PLoS Biol. 2019;17(9):e3000460. doi:10.1371/journal.pbio.3000460
Abstract:
There is presently a very limited understanding of the mechanisms that underlie the evolution of new cell types. The skeleton-...
Delivery Method:
microinjection
Organism or Cell Type:
Lytechinus variegatus (sea urchin)
Citation Extract:
Ettensohn CA, Adomako-Ankomah A. The evolution of a new cell type was associated with competition for a signaling ligand. PLoS Biol. 2019;17(9):e3000460. doi:10.1371/journal.pbio.3000460.

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers

Authors:
Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA
Citation:
Sci Adv. 2019;5(9):eaax1734. doi:10.1126/sciadv.aax1738
Abstract:
The BAP1 tumor suppressor is mutated in many human cancers such as uveal melanoma, leading to poor patient outcome. It remains...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kuznetsov JN, Aguero TH, Owens DA, Kurtenbach S, Field MG, Durante MA. BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers. Sci Adv. 2019;5(9):eaax1734. doi:10.1126/sciadv.aax1738.

TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in Zebrafish

Authors:
Fillatre J, Fauny JD, Fels JA, Li C, Goll M, Thisse C, Thisse B
Citation:
Elife. 2019 Sep 12;8. pii: e45241. doi: 10.7554/eLife.45241. [Epub ahead of print]
Abstract:
In many vertebrates, establishment of Left-Right (LR) asymmetry results from the activity of a ciliated organ functioning as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fillatre J, Fauny JD, Fels JA, Li C, Goll M, Thisse C, Thisse B. TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in Zebrafish. Elife. 2019 Sep 12;8. pii: e45241. doi: 10.7554/eLife.45241. [Epub ahead of print].

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