You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10101 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Complement component C1q plays a critical role in VLRA/VLRC-mediated immune response

Authors:
Li J, Ma Q, Liu H, Song X, Pang Y, Su P, Sun F, Gou M, Lu J, Shan Y, Liu X, Li Q, Han Y
Citation:
Dev Comp Immunol. 2020;[Epub ahead of print] doi:10.1016/j.dci.2020.103750
Abstract:
In jawless vertebrates, the lamprey complement component C1q (LC1q) acts as a lectin and activates lamprey complement component...
Delivery Method:
microinjection
Organism or Cell Type:
Lampetra morii (lamprey)
Citation Extract:
Li J, Ma Q, Liu H, Song X, Pang Y, Su P, Sun F, Gou M, Lu J, Shan Y, Liu X, Li Q, Han Y. Complement component C1q plays a critical role in VLRA/VLRC-mediated immune response. Dev Comp Immunol. 2020;[Epub ahead of print] doi:10.1016/j.dci.2020.103750.

Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development

Authors:
Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDC, Gaulton KJ, Sander M
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.18.101071
Abstract:
Genetic variants associated with type 2 diabetes (T2D) risk affect gene regulation in metabolically relevant tissues, such as...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDC, Gaulton KJ, Sander M. Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.18.101071 .

Cadherin-11 is required for neural crest determination and survival

Authors:
Manohar S, Camacho-Magallanes A, Rogers CD
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.18.066613
Abstract:
Neural crest (NC) cells are multipotent embryonic cells that form melanocytes, craniofacial bone and cartilage, and the...
Delivery Method:
injection then electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Manohar S, Camacho-Magallanes A, Rogers CD. Cadherin-11 is required for neural crest determination and survival. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.18.066613.

Zygotic Vsx1 Plays a Key Role in Defining V2a Interneuron Sub-Lineage by Directly Repressing tal1 Transcription in Zebrafish

Authors:
Zhang Q, Xu H, Zhao W, Zheng J, Sun L, Luo C
Citation:
Int J Mol Sci. 2020;21(10):2020. doi:10.3390/ijms21103600
Abstract:
In the spinal cord, excitatory V2a and inhibitory V2b interneurons are produced together by the final division of common P2...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Q, Xu H, Zhao W, Zheng J, Sun L, Luo C. Zygotic Vsx1 Plays a Key Role in Defining V2a Interneuron Sub-Lineage by Directly Repressing tal1 Transcription in Zebrafish. Int J Mol Sci. 2020;21(10):2020. doi:10.3390/ijms21103600.

Identification of Transient Receptor Potential Channel 4-Associated Protein as a Novel Candidate Gene Causing Congenital Primary Hypothyroidism

Authors:
Choukair D, Eberle B, Vick P, Hermanns P, Weiss B, Paramasivam N, Schlesner M, Lornsen K, Roeth R, Klutmann C, Kreis J, Hoffmann GF, Pohlenz J, Rappold GA, Bettendorf M
Citation:
Horm Res Paediatr. 2020;[Epub aheaed of print] doi:10.1159/000507114
Abstract:
Background: Congenital primary hypothyroidism (CH) is the most common endocrine disorder in neonates. Methods: To identify...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Choukair D, Eberle B, Vick P, Hermanns P, Weiss B, Paramasivam N, Schlesner M, Lornsen K, Roeth R, Klutmann C, Kreis J, Hoffmann GF, Pohlenz J, Rappold GA, Bettendorf M. Identification of Transient Receptor Potential Channel 4-Associated Protein as a Novel Candidate Gene Causing Congenital Primary Hypothyroidism. Horm Res Paediatr. 2020;[Epub aheaed of print] doi:10.1159/000507114.

Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish

Authors:
El Maï M, Marzullo M, de Castro IP, Ferreira MG
Citation:
eLife. 2020;9:e54935. doi:10.7554/eLife.54935
Abstract:
Progressive telomere shortening during lifespan is associated with restriction of cell proliferation, genome instability and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
El Maï M, Marzullo M, de Castro IP, Ferreira MG. Opposing p53 and mTOR/AKT promote an in vivo switch from apoptosis to senescence upon telomere shortening in zebrafish. eLife. 2020;9:e54935. doi:10.7554/eLife.54935.

De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome

Authors:
Ufartes R, Berger H, Till K, Salinas G, Sturm M, Altmüller J, Nürnberg P, Thiele H, Funke R, Apeshiotis N, Langen H, Wollnik B, Borchers A, Pauli S
Citation:
Hum Genet. 2020 May 18. doi: 10.1007/s00439-020-02175-x. Online ahead of print
Abstract:
We report truncating de novo variants in specific exons of FBRSL1 in three unrelated children with an overlapping syndromic...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ufartes R, Berger H, Till K, Salinas G, Sturm M, Altmüller J, Nürnberg P, Thiele H, Funke R, Apeshiotis N, Langen H, Wollnik B, Borchers A, Pauli S. De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome. Hum Genet. 2020 May 18. doi: 10.1007/s00439-020-02175-x. Online ahead of print.

The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology

Authors:
Barnum CE, Al Saai S, Patel SD, Cheng C, Anand D, Xu X, Dash S, Siddam AD, Glazewski L, Paglione E, Polson SW, Chuma S, Mason RW, Wei S, Batish M, Fowler VM, Lachke SA
Citation:
Hum Molec Genet. 2020;[Epub ahead of print] doi:10.1093/hmg/ddaa096
Abstract:
Mutations of the RNA-granule component TDRD7 (OMIM: 611258) cause pediatric cataract. We applied an integrated approach to...
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Barnum CE, Al Saai S, Patel SD, Cheng C, Anand D, Xu X, Dash S, Siddam AD, Glazewski L, Paglione E, Polson SW, Chuma S, Mason RW, Wei S, Batish M, Fowler VM, Lachke SA. The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology. Hum Molec Genet. 2020;[Epub ahead of print] doi:10.1093/hmg/ddaa096.

RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function

Authors:
Shi B, Zhang J, Heng J, Gong J, Zhang T, Li P, Sun B-F, Yang Y, Zhang N, Zhao Y-L, Wang H-L, Liu F, Zhang QC, Yang Y-G
Citation:
Genome Biol. 2020;21(1):120 doi:10.1186/s13059-020-02022-2
Abstract:
Background: Vertebrate early embryogenesis is initially directed by a set of maternal RNAs and proteins, yet the mechanisms...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shi B, Zhang J, Heng J, Gong J, Zhang T, Li P, Sun B-F, Yang Y, Zhang N, Zhao Y-L, Wang H-L, Liu F, Zhang QC, Yang Y-G. RNA structural dynamics regulate early embryogenesis through controlling transcriptome fate and function. Genome Biol. 2020;21(1):120 doi:10.1186/s13059-020-02022-2.

Polarized endosome dynamics engage cytosolic Par-3 and dynein during asymmetric division

Authors:
Zhao X, Tong K, Chen X, Yang B, Li Q, Dai Z, Shi X, Seiple I, Huang B, Guo S
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.05.15.098012
Abstract:
Asymmetric cell division (ACD), which produces two daughters with different fates, is fundamental for generating cellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao X, Tong K, Chen X, Yang B, Li Q, Dai Z, Shi X, Seiple I, Huang B, Guo S. Polarized endosome dynamics engage cytosolic Par-3 and dynein during asymmetric division. bioRxiv. 2020;[preprint] doi:10.1101/2020.05.15.098012 .

Pages