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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
Antisense phosphorodiamidate morpholino oligomers retain activity in Burkholderia cepacia complex biofilm
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Citation:
Frontiers in Microbiology. Volume 16 - 2025, 2025. doi: 10.3389/fmicb.2025.1660799 Epub:
Not Epub Abstract:
Background: Members of the Burkholderia cepacia complex (Bcc) are known to cause severe pulmonary infections in... Delivery Method:
peptide-linked Organism or Cell Type:
Burkholderia cepacia Citation Extract: Mendez AR, Pybus C, Greenberg DE. Antisense phosphorodiamidate morpholino oligomers retain activity in Burkholderia cepacia complex biofilm. Frontiers in Microbiology. Volume 16 - 2025, 2025. doi: 10.3389/fmicb.2025.1660799. |
Reactive Oxygen Species Counteract Zebrafish Wound Contraction and Promote Wound Healing
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Citation:
Biophys J. 2025 Sep 19:S0006-3495(25)00607-1. doi: 10.1016/j.bpj.2025.09.027. Epub ahead of print. PMID: 40975783 Epub:
Not Epub Abstract:
Reactive oxygen species (ROS) are second messengers that drive wound closure. However, the mechanism by which ROS regulate... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ding C, Li L, Wang Y, Nguyen HA, Chan DD, Umulis DM, Buganza AT, Deng Q. Reactive Oxygen Species Counteract Zebrafish Wound Contraction and Promote Wound Healing. Biophys J. 2025 Sep 19:S0006-3495(25)00607-1. doi: 10.1016/j.bpj.2025.09.027. Epub ahead of print. PMID: 40975783. |
Bone morphogenetic protein-mediated Ventx3.2 regulates mesendoderm patterning and gut morphogenesis during Xenopus embryogenesis
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Citation:
Biochem Biophys Res Commun. 2025 Sep 10;784:152623. doi: 10.1016/j.bbrc.2025.152623. Epub ahead of print. PMID: 40967030 Epub:
Not Epub Abstract:
Bone morphogenetic protein (BMP) signaling plays a pivotal role in germ layer specification and organogenesis during vertebrate... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Goutam RS, Kumar V, Lee U, Kim J. Bone morphogenetic protein-mediated Ventx3.2 regulates mesendoderm patterning and gut morphogenesis during Xenopus embryogenesis. Biochem Biophys Res Commun. 2025 Sep 10;784:152623. doi: 10.1016/j.bbrc.2025.152623. Epub ahead of print. PMID: 40967030. |
Dysregulated RNA splicing impairs regeneration in alcohol-associated liver disease
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Citation:
Nat Commun. 2025 Sep 10;16(1):8049. doi: 10.1038/s41467-025-63251-2. PMID: 40931030; PMCID: PMC12423296 Epub:
Not Epub Abstract:
Individuals with progressive liver failure risk dying without liver transplantation. However, our understanding of why... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: AML12 Citation Extract: Chembazhi UV, Bangru S, Dutta RK, Das D, Peiffer B, Natua S, Toohill K, Leona A, Purwar I, Bhowmik A, Goyal Y, Sun Z, Diehl AM, Kalsotra A. Dysregulated RNA splicing impairs regeneration in alcohol-associated liver disease. Nat Commun. 2025 Sep 10;16(1):8049. doi: 10.1038/s41467-025-63251-2. PMID: 40931030; PMCID: PMC12423296. |
Tulp3 deficiency results in ciliopathy phenotypes during zebrafish embryogenesis
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Citation:
Sci Rep 15, 32435 (2025). https://doi.org/10.1038/s41598-025-16584-3 Epub:
Not Epub Abstract:
Ciliopathies, caused by defective cilia biogenesis or function, comprise a genetically and clinically diverse group of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Epting D, Devane J, Mertes R, Kayser S, Helmstädter M, Metzger P, Boerries M, Bergmann C, Ott E. Tulp3 deficiency results in ciliopathy phenotypes during zebrafish embryogenesis. Sci Rep 15, 32435 (2025). https://doi.org/10.1038/s41598-025-16584-3. |
MicroRNA miR-196a controls neural crest patterning by repressing immature neural ectoderm programs in Xenopus embryos
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Citation:
Developmental Biology, 2025, ISSN 0012-1606, https://doi.org/10.1016/j.ydbio.2025.09.007 Epub:
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Neural crest (NC) cells form a multipotent stem cell population specified during neurulation, which undergo an epithelial-to-... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Godden AM, Ward N, Sittewelle M, Antonaci M, Mir R, Kotov A, Monsoro-Burq AH, Wheeler GN. MicroRNA miR-196a controls neural crest patterning by repressing immature neural ectoderm programs in Xenopus embryos. Developmental Biology, 2025, ISSN 0012-1606, https://doi.org/10.1016/j.ydbio.2025.09.007. |
Morpholino-based phosphorothioate analogs via oxathiaphospholane chemistry: synthesis, structural insights and stability
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Citation:
Org Biomol Chem. 2025 Sep 10. doi: 10.1039/d5ob01223f. Epub ahead of print. PMID: 40928893 Epub:
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We present the application of the oxathiaphospholane method for the synthesis of novel P-stereodefined phosphorothioate N-... Delivery Method:
none Organism or Cell Type:
none Citation Extract: Jastrzębska K, Szymańska A, Pawlak T, Dolot R. Morpholino-based phosphorothioate analogs via oxathiaphospholane chemistry: synthesis, structural insights and stability. Org Biomol Chem. 2025 Sep 10. doi: 10.1039/d5ob01223f. Epub ahead of print. PMID: 40928893. |
Unified mass imaging maps the lipidome of vertebrate development
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Citation:
Nat Methods. 2025 Sep 3. doi: 10.1038/s41592-025-02771-7. Epub ahead of print. PMID: 40903641 Epub:
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Embryo development entails the formation of anatomical structures with distinct biochemical compositions. Compared with the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schede HH, Alieh LHA, Rohde LA, Herrera A, Schlaeppi A, Valentin G, Gargoori Motlagh A, Dominguez Mantes A, Jollivet C, Paz-Montoya J, Capolupo L, Khven I, Oates AC, D'Angelo G, La Manno G. Unified mass imaging maps the lipidome of vertebrate development. Nat Methods. 2025 Sep 3. doi: 10.1038/s41592-025-02771-7. Epub ahead of print. PMID: 40903641. |
Unraveling the regulative development and molecular mechanisms of identical sea urchin twins
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Citation:
Nat Commun. 2025 Sep 5;16(1):8005. doi: 10.1038/s41467-025-63111-z. PMID: 40913033; PMCID: PMC12413439 Epub:
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Since Hans Driesch’s pioneering work in 1891, it has been known that animal embryos can develop into complete individuals even... Delivery Method:
microinjection Organism or Cell Type:
H. pulcherrimus, S. purpuratus, Strongylocentrotus intermedius, Temnopleurus reevesii (sea urchin) Citation Extract: Suzuki H, Yaguchi J, Tsuyuzaki K, Yaguchi S. Unraveling the regulative development and molecular mechanisms of identical sea urchin twins. Nat Commun. 2025 Sep 5;16(1):8005. doi: 10.1038/s41467-025-63111-z. PMID: 40913033; PMCID: PMC12413439. |
The role of REST in regulating the BDNF/TrkB signalling pathway in nano-alumina induced cognitive dysfunction in zebrafish
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Citation:
Ecotoxicol Environ Saf. 2025 Sep 4;303:118998. doi: 10.1016/j.ecoenv.2025.118998. Epub ahead of print. PMID: 40912099 Epub:
Not Epub Abstract:
Synaptic plasticity is fundamental for cognitive development and brain function. Aluminium nanoparticles (AlNPs), widely used... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang J, Wang S, Jin Z, Ma L, Wang Y, Zhang H, Nie J, Niu Q. The role of REST in regulating the BDNF/TrkB signalling pathway in nano-alumina induced cognitive dysfunction in zebrafish. Ecotoxicol Environ Saf. 2025 Sep 4;303:118998. doi: 10.1016/j.ecoenv.2025.118998. Epub ahead of print. PMID: 40912099. |