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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9382 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer

Authors:
Daulat AM, Finetti P, Revinski D, Wagner MS, Camoin L, Audebert S, Birnbaum D, Kodjabachian L, Borg J-P, Bertucci F
Citation:
Brit J Cancer. 2019;[Epub ahead of print] doi:doi.org/10.1038/s41416-019-0448-z
Abstract:
Background: Triple-negative breast cancers (TNBC) are poor-prognosis tumours candidate to chemotherapy as only systemic...
Organism or Cell Type:
Xenopus
Citation Extract:
Daulat AM, Finetti P, Revinski D, Wagner MS, Camoin L, Audebert S, Birnbaum D, Kodjabachian L, Borg J-P, Bertucci F. ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer. Brit J Cancer. 2019;[Epub ahead of print] doi:doi.org/10.1038/s41416-019-0448-z.

Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation

Authors:
Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang C-C, Lee J, Demer LL, Tintut Y, Marsden AL, Hsiai TK
Citation:
JCI Insight. 2019;[in-press preview] doi:10.1172/jci.insight.124460
Abstract:
Biomechanical forces and endothelial-to-mesenchymal transition (EndoMT) are known to mediate valvulogenesis. However, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hsu JJ, Vedula V, Baek KI, Chen C, Chen J, Chou MI, Lam J, Subhedar S, Wang J, Ding Y, Chang C-C, Lee J, Demer LL, Tintut Y, Marsden AL, Hsiai TK. Contractile and hemodynamic forces coordinate Notch1b-mediated outflow tract valve formation. JCI Insight. 2019;[in-press preview] doi:10.1172/jci.insight.124460.

The voltage sensing phosphatase (VSP) localizes to the apical membrane of kidney tubule epithelial cells

Authors:
Ratzan W, Rayaprolu V, Killian SE, Bradley R, Kohout SC
Citation:
PLoS ONE. 2019;14(4):e0209056. doi:10.1371/journal.pone.0209056
Abstract:
Voltage-sensing phosphatases (VSPs) are transmembrane proteins that couple changes in membrane potential to hydrolysis of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ratzan W, Rayaprolu V, Killian SE, Bradley R, Kohout SC. The voltage sensing phosphatase (VSP) localizes to the apical membrane of kidney tubule epithelial cells. PLoS ONE. 2019;14(4):e0209056. doi:10.1371/journal.pone.0209056.

Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis

Authors:
Gong B, Li Z, Xiao W, Li G, Ding S, Meng A, Jia S
Citation:
Nat Comm. 2019;10(1):1606 doi:10.1038/s41467-019-09604-0
Abstract:
Vascular endothelial growth factor (VEGF) regulates vasculogenesis by using its tyrosine kinase receptors. However, little is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gong B, Li Z, Xiao W, Li G, Ding S, Meng A, Jia S. Sec14l3 potentiates VEGFR2 signaling to regulate zebrafish vasculogenesis. Nat Comm. 2019;10(1):1606 doi:10.1038/s41467-019-09604-0.

Clec14a genetically interacts with Etv2 and Vegf signaling during vasculogenesis and angiogenesis in zebrafish

Authors:
Pociute K, Schumacher JA, Sumanas S
Citation:
BMC Dev Biol. 2019 Apr 5;19(1):6. doi: 10.1186/s12861-019-0188-6
Abstract:
BACKGROUND: C-lectin family 14 Member A (Clec14a) is a transmembrane protein specifically expressed in vascular endothelial...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pociute K, Schumacher JA, Sumanas S. Clec14a genetically interacts with Etv2 and Vegf signaling during vasculogenesis and angiogenesis in zebrafish. BMC Dev Biol. 2019 Apr 5;19(1):6. doi: 10.1186/s12861-019-0188-6.

Analysis of microRNA functions

Authors:
Remsburg C, Konrad K, Sampilo NF, Song JL
Citation:
Methods Cell Biol. 2019;151:323-334. doi: 10.1016/bs.mcb.2018.10.005. Epub 2018 Dec 11
Abstract:
MicroRNAs (miRNAs) are small non-coding RNAs that repress the translation and reduce the stability of target mRNAs in animal...
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Remsburg C, Konrad K, Sampilo NF, Song JL. Analysis of microRNA functions. Methods Cell Biol. 2019;151:323-334. doi: 10.1016/bs.mcb.2018.10.005. Epub 2018 Dec 11.

Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?

Authors:
Zimmer AM, Pan YK, Chandrapalan T, Kwong RWM, Perry SF
Citation:
J Exp Biol. 2019 Apr 4;222(Pt 7). pii: jeb175737. doi: 10.1242/jeb.175737. Review
Abstract:
Loss-of-function technologies, such as morpholino- and RNAi-mediated gene knockdown, and TALEN- and CRISPR/Cas9-mediated gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zimmer AM, Pan YK, Chandrapalan T, Kwong RWM, Perry SF. Loss-of-function approaches in comparative physiology: is there a future for knockdown experiments in the era of genome editing?. J Exp Biol. 2019 Apr 4;222(Pt 7). pii: jeb175737. doi: 10.1242/jeb.175737. Review.

Prostaglandin signaling regulates renal multiciliated cell specification and maturation

Authors:
Marra AN, Adeeb BD, Chambers BE, Drummond BE, Ulrich M, Addiego A, Springer M, Poureetezadi SJ, Chambers JM, Ronshaugen M, Wingert RA
Citation:
Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1813492116
Abstract:
Multiciliated cells (MCCs) are specialized epithelia with apical bundles of motile cilia that direct fluid flow. MCC...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marra AN, Adeeb BD, Chambers BE, Drummond BE, Ulrich M, Addiego A, Springer M, Poureetezadi SJ, Chambers JM, Ronshaugen M, Wingert RA. Prostaglandin signaling regulates renal multiciliated cell specification and maturation. Proc Nat Acad Sci USA. 2019;[Epub ahead of print] doi:10.1073/pnas.1813492116.

GPCR-independent activation of G proteins promotes apical cell constriction in vivo

Authors:
Marivin A, Morozova V, Walawalkar I, Leyme A, Kretov DA, Cifuentes D, Dominguez I, Garcia-Marcos M
Citation:
J Cell Biol. 2019;[Epub ahead of print] doi:10.1083/jcb.201811174
Abstract:
Heterotrimeric G proteins are signaling switches that control organismal morphogenesis across metazoans. In invertebrates,...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Marivin A, Morozova V, Walawalkar I, Leyme A, Kretov DA, Cifuentes D, Dominguez I, Garcia-Marcos M. GPCR-independent activation of G proteins promotes apical cell constriction in vivo. J Cell Biol. 2019;[Epub ahead of print] doi:10.1083/jcb.201811174.

Extracellular Matrix Signaling Through β3 Integrin Mediates Cocaine Cue-induced Transient Synaptic Plasticity and Relapse

Authors:
Garcia-Keller C, Neuhofer D, Bobadilla A-C, Spencer S, Chioma V, Monforton C, Kalivas PW
Citation:
Biol Psych. 2019;[Epub ahead of print] doi:10.1016/j.biopsych.2019.03.982
Abstract:
Background: Cue-induced relapse to drug use is a primary symptom of cocaine addiction. Cue-induced transient excitatory...
Organism or Cell Type:
rats
Citation Extract:
Garcia-Keller C, Neuhofer D, Bobadilla A-C, Spencer S, Chioma V, Monforton C, Kalivas PW. Extracellular Matrix Signaling Through β3 Integrin Mediates Cocaine Cue-induced Transient Synaptic Plasticity and Relapse. Biol Psych. 2019;[Epub ahead of print] doi:10.1016/j.biopsych.2019.03.982.

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