You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9322 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis

Authors:
Cooper-Knock J, Moll T, Ramesh T, Castelli L, Beer A, Robins H, Fox I, Niedermoser I, Van Damme P, Moisse M, Robberecht W, Hardiman O, Panades MP, Assialioui A, Mora JS, Basak AN, Morrison KE, Shaw CE, Al-Chalabi A, Landers JE, Wyles M, Heath PR, Higginbottom A, Walsh T, Kazoka M, McDermott CJ, Hautbergue GM, Kirby J, Shaw PJ
Citation:
Cell Rep. 2019;26(9):2298-306. doi:10.1016/j.celrep.2019.02.006
Abstract:
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disorder without effective neuroprotective therapy. Known...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cooper-Knock J, Moll T, Ramesh T, Castelli L, Beer A, Robins H, Fox I, Niedermoser I, Van Damme P, Moisse M, Robberecht W, Hardiman O, Panades MP, Assialioui A, Mora JS, Basak AN, Morrison KE, Shaw CE, Al-Chalabi A, Landers JE, Wyles M, Heath PR, Higginbottom A, Walsh T, Kazoka M, McDermott CJ, Hautbergue GM, Kirby J, Shaw PJ. Mutations in the Glycosyltransferase Domain of GLT8D1 Are Associated with Familial Amyotrophic Lateral Sclerosis. Cell Rep. 2019;26(9):2298-306. doi:10.1016/j.celrep.2019.02.006.

A familial congenital heart disease with a possible multigenic origin involving a mutation in BMPR1A

Authors:
Demal TJ, Heise M, Reiz B, Dogra D, Brænne I, Reichenspurner H, Männer J, Aherrahrou Z, Schunkert H, Erdmann J, Abdelilah-Seyfried S
Citation:
Sci Rep. 2019;9:2959. doi:10.1038/s41598-019-39648-7
Abstract:
The genetics of many congenital heart diseases (CHDs) can only unsatisfactorily be explained by known chromosomal or Mendelian...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Demal TJ, Heise M, Reiz B, Dogra D, Brænne I, Reichenspurner H, Männer J, Aherrahrou Z, Schunkert H, Erdmann J, Abdelilah-Seyfried S. A familial congenital heart disease with a possible multigenic origin involving a mutation in BMPR1A. Sci Rep. 2019;9:2959. doi:10.1038/s41598-019-39648-7.

Fluid dynamics during bleb formation in migrating cells in vivo

Authors:
Goudarzi M, Boquet-Pujadas A, Olivo-Marin J-C, Raz E
Citation:
PLoS ONE. 2019;14(2): e0212699. doi:10.1371/journal.pone.0212699
Abstract:
Blebs are cellular protrusions observed in migrating cells and in cells undergoing spreading, cytokinesis, and apoptosis. Here...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goudarzi M, Boquet-Pujadas A, Olivo-Marin J-C, Raz E. Fluid dynamics during bleb formation in migrating cells in vivo. PLoS ONE. 2019;14(2): e0212699. doi:10.1371/journal.pone.0212699.

The wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis

Authors:
Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M
Citation:
Dev Biol. 2019 Feb 21. pii: S0012-1606(18)30559-1. doi: 10.1016/j.ydbio.2019.02.009. [Epub ahead of print]
Abstract:
Wnt proteins can activate different intracellular signaling pathways. These pathways need to be tightly regulated for proper...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Guo Y, Dorn T, Kühl SJ, Linnemann A, Rothe M, Pfister AS, Vainio S, Laugwitz KL, Moretti A, Kühl M. The wnt inhibitor Dkk1 is required for maintaining the normal cardiac differentiation program in Xenopus laevis. Dev Biol. 2019 Feb 21. pii: S0012-1606(18)30559-1. doi: 10.1016/j.ydbio.2019.02.009. [Epub ahead of print].

ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth

Authors:
Zhang Y, Ji D, Li L, Yang S, Zhang H, Duan X
Citation:
Theranostics. 2019;9(5):1387-1400. doi:10.7150/thno.29761
Abstract:
Human CLCN7 encodes voltage-gated chloride channel 7 (ClC-7); mutations of CLCN7 lead to osteopetrosis which is characterized...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Ji D, Li L, Yang S, Zhang H, Duan X. ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth. Theranostics. 2019;9(5):1387-1400. doi:10.7150/thno.29761.

Tulotta C, Stefanescu C, Chen Q, Torraca V, Meijer AH, Snaar-Jagalska BE

Authors:
CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells
Citation:
Sci Rep. 2019;9:2399 doi:10.1038/s41598-019-38643-2
Abstract:
Developing tumors interact with the surrounding microenvironment. Myeloid cells exert both anti- and pro-tumor functions and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
CXCR4 signaling regulates metastatic onset by controlling neutrophil motility and response to malignant cells. Tulotta C, Stefanescu C, Chen Q, Torraca V, Meijer AH, Snaar-Jagalska BE. Sci Rep. 2019;9:2399 doi:10.1038/s41598-019-38643-2.

Microinjection methods for sea urchin eggs and blastomeres

Authors:
Yaguchi J
Citation:
Methods Cell Biol. 2019;150:173-188. doi: 10.1016/bs.mcb.2018.09.013. Epub 2019 Jan 28
Abstract:
Methods for microinjection into sea urchin eggs have become relatively easier because of the technical improvements by a number...
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus, Temnopleurus reevesii, Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
Yaguchi J. Microinjection methods for sea urchin eggs and blastomeres. Methods Cell Biol. 2019;150:173-188. doi: 10.1016/bs.mcb.2018.09.013. Epub 2019 Jan 28.

Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

Authors:
Young RM, Hawkins TA, Cavodeassi F, Stickney HL, Schwarz Q, Lawrence LM, Wierzbicki C, Cheng BYL, Luo J, Ambrosio EM, Klosner A, Sealy IM, Rowell J, Trivedi CA, Bianco IH, Allende ML, Busch-Nentwich EM, Gestri G, Wilson SW
Citation:
eLife. 2019;8:e40093 doi:10.7554/eLife.40093
Abstract:
The vertebrate eye originates from the eye field, a domain of cells specified by a small number of transcription factors. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Young RM, Hawkins TA, Cavodeassi F, Stickney HL, Schwarz Q, Lawrence LM, Wierzbicki C, Cheng BYL, Luo J, Ambrosio EM, Klosner A, Sealy IM, Rowell J, Trivedi CA, Bianco IH, Allende ML, Busch-Nentwich EM, Gestri G, Wilson SW. Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification. eLife. 2019;8:e40093 doi:10.7554/eLife.40093.

Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function

Authors:
Li X-J, Zhu L, Chen L, Yan L, Perkins B, Li S, Li B, Xu HA
Citation:
Front Cell Neurosci. 2019;[Epub] doi:doi: 10.3389/fncel.2019.00081
Abstract:
Joubert syndrome (JBTS) is an inherited autosomal recessive disorder associated with cerebellum and brainstem malformation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X-J, Zhu L, Chen L, Yan L, Perkins B, Li S, Li B, Xu HA. Mutant Ahi1 affects retinal axon projection in zebrafish via toxic gain of function. Front Cell Neurosci. 2019;[Epub] doi:doi: 10.3389/fncel.2019.00081.

Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos

Authors:
Vázquez-Diez C, Paim LMG, FitzHarris G
Citation:
Curr Biol. 2019 Jan 17. pii: S0960-9822(18)31676-2. doi: 10.1016/j.cub.2018.12.042. [Epub ahead of print]
Abstract:
Chromosome segregation errors during mammalian preimplantation development cause "mosaic" embryos comprising a...
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Vázquez-Diez C, Paim LMG, FitzHarris G. Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos. Curr Biol. 2019 Jan 17. pii: S0960-9822(18)31676-2. doi: 10.1016/j.cub.2018.12.042. [Epub ahead of print].

Pages