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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12338 scientific papers returned from the database with the search filters currently being used below.
There are 12338 scientific papers returned from the database with the search filters currently being used below.
Double assurance in the induction of axial development by egg dorsal determinants in Xenopus embryos
Citation:
Proc Natl Acad Sci U S A. 2025 Feb 18;122(7):e2421772122. doi: 10.1073/pnas.2421772122. Epub 2025 Feb 10. PMID: 39928870; PMCID: PMC11848351 Epub:
Not Epub Abstract:
We recently reported that microinjection of Xenopus nodal-related (xnr) mRNAs into β-catenin-depleted Xenopus embryos rescued a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Azbazdar Y, De Robertis EM. Double assurance in the induction of axial development by egg dorsal determinants in Xenopus embryos. Proc Natl Acad Sci U S A. 2025 Feb 18;122(7):e2421772122. doi: 10.1073/pnas.2421772122. Epub 2025 Feb 10. PMID: 39928870; PMCID: PMC11848351. |
Alternative splicing of CADM1 is associated with endothelial progenitor cell dysfunction in preeclampsia
Citation:
Physiol Genomics. 2025 Feb 10. doi: 10.1152/physiolgenomics.00006.2024. Epub ahead of print. PMID: 39928918 Epub:
Not Epub Abstract:
Preeclampsia is a pregnancy specific hypertensive disorder and is associated with an increased postpartum risk of... Delivery Method:
Lipofectamine 3000 Organism or Cell Type:
cell culture: cord blood endothelial colony forming cells (ECFCs) Citation Extract: Welz R, Ramachandran D, Schröder-Heurich B, Richter K, Geffers R, von Kaisenberg CS, Dörk T, von Versen-Höynck F. Alternative splicing of CADM1 is associated with endothelial progenitor cell dysfunction in preeclampsia. Physiol Genomics. 2025 Feb 10. doi: 10.1152/physiolgenomics.00006.2024. Epub ahead of print. PMID: 39928918. |
CMTM4 is an adhesion modulator that regulates skeletal patterning and primary mesenchyme cell migration in sea urchin embryos
Citation:
Dev Biol. 2025 Feb 11;521:85-95. doi: 10.1016/j.ydbio.2025.02.009. Epub ahead of print. PMID: 39947420 Epub:
Not Epub Abstract:
MARVEL proteins, including those of the CMTM gene family, are multi-pass transmembrane proteins that play important roles in... Delivery Method:
microinjection Organism or Cell Type:
Lytechinus variegatus (sea urchin) Citation Extract: Descoteaux AE, Radulovic M, Alburi D, Bradham CA. CMTM4 is an adhesion modulator that regulates skeletal patterning and primary mesenchyme cell migration in sea urchin embryos. Dev Biol. 2025 Feb 11;521:85-95. doi: 10.1016/j.ydbio.2025.02.009. Epub ahead of print. PMID: 39947420. |
CRISPR-Cas13d as a molecular tool to achieve targeted gene expression knockdown in chick embryos
Citation:
Dev Biol. 2025 Mar;519:5-12. doi: 10.1016/j.ydbio.2024.11.013. Epub 2024 Nov 30. PMID: 39622311; PMCID: PMC11824683 Epub:
Not Epub Abstract:
The chick embryo is a classical model system commonly used in developmental biology due to its amenability to gene perturbation... Delivery Method:
electroporation Organism or Cell Type:
chick embryo Citation Extract: Kim M, Hutchins EJ. CRISPR-Cas13d as a molecular tool to achieve targeted gene expression knockdown in chick embryos. Dev Biol. 2025 Mar;519:5-12. doi: 10.1016/j.ydbio.2024.11.013. Epub 2024 Nov 30. PMID: 39622311; PMCID: PMC11824683. |
A peptide conjugate enables systemic injection of the morpholino inducer and more durable induction of T3H38 ribozyme-controlled AAV transgene in mice
Citation:
Gene Ther. 2025 Feb 12. doi: 10.1038/s41434-025-00519-8. Epub ahead of print. PMID: 39939797 Epub:
Not Epub Abstract:
Genetic switches that allow for precise control over transgene expression timing or levels may improve the safety and expand... Delivery Method:
peptide-linked, Vivo-Morpholino Organism or Cell Type:
mouse Citation Extract: Tang X, Wang H, Yin Y, Zhong G. A peptide conjugate enables systemic injection of the morpholino inducer and more durable induction of T3H38 ribozyme-controlled AAV transgene in mice. Gene Ther. 2025 Feb 12. doi: 10.1038/s41434-025-00519-8. Epub ahead of print. PMID: 39939797. |
A Population Pharmacokinetic Model to Inform Extension of the Eteplirsen Dosing Regimen Across the Broad DMD Population
Citation:
CPT Pharmacometrics Syst Pharmacol. 2025 Feb 26. doi: 10.1002/psp4.70001. Epub ahead of print. PMID: 40009522 Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is characterized by progressive, irreversible muscle damage that usually leads to premature... Delivery Method:
intravenous (i.v.) infusion Organism or Cell Type:
human Citation Extract: Patel Y, Orogun L, Yocum N, Rodino-Klapac LR, East L. A Population Pharmacokinetic Model to Inform Extension of the Eteplirsen Dosing Regimen Across the Broad DMD Population. CPT Pharmacometrics Syst Pharmacol. 2025 Feb 26. doi: 10.1002/psp4.70001. Epub ahead of print. PMID: 40009522. |
Improved induction of ribozyme-controlled AAV transgene via peptide-conjugated morpholino oligos
Citation:
Gene Ther. 2025 Feb 26. doi: 10.1038/s41434-025-00520-1. Epub ahead of print. PMID: 40011707 Epub:
Not Epub Abstract:
Genetic switches that allow for precise control over transgene expression timing or levels may improve the safety and expand... Delivery Method:
peptide-linked Organism or Cell Type:
mouse Citation Extract: Cheng T, Chen B, Zou W. Improved induction of ribozyme-controlled AAV transgene via peptide-conjugated morpholino oligos. Gene Ther. 2025 Feb 26. doi: 10.1038/s41434-025-00520-1. Epub ahead of print. PMID: 40011707. |
Unveiling the role of RPS17 and SLC4A1 in diamond-Blackfan Anemia: A zebrafish-based study
Citation:
Blood Cells Mol Dis. 2025 Feb 25;112:102912. doi: 10.1016/j.bcmd.2025.102912. Epub ahead of print. PMID: 40015014 Epub:
Not Epub Abstract:
Diamond-Blackfan Anemia (DBA) is a rare congenital disorder characterized by macrocytic anemia, physical abnormalities, and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kim K, Lee H, Ahn S, Kim YH, Oh CK . Unveiling the role of RPS17 and SLC4A1 in diamond-Blackfan Anemia: A zebrafish-based study. Blood Cells Mol Dis. 2025 Feb 25;112:102912. doi: 10.1016/j.bcmd.2025.102912. Epub ahead of print. PMID: 40015014. |
TGF-β signaling controls neural crest developmental plasticity via SMAD2/3
Citation:
Dev Cell. 2025 Feb 18:S1534-5807(25)00059-0. doi: 10.1016/j.devcel.2025.01.018. Epub ahead of print. PMID: 39983721 Epub:
Not Epub Abstract:
The neural crest is a highly plastic stem cell population that represents an exception to the germ layer theory. Despite being... Delivery Method:
electroporation Organism or Cell Type:
chick embryo Citation Extract: Rothstein M, Azambuja AP, Kanno TY, Breen C, Simoes-Costa M. TGF-β signaling controls neural crest developmental plasticity via SMAD2/3. Dev Cell. 2025 Feb 18:S1534-5807(25)00059-0. doi: 10.1016/j.devcel.2025.01.018. Epub ahead of print. PMID: 39983721. |
Dominant rhabdomyolysis linked to a recurrent ATP2A2 variant reducing SERCA2 function in muscle
Citation:
Brain. 2025 Feb 19:awaf067. doi: 10.1093/brain/awaf067. Epub ahead of print. PMID: 39970126 Epub:
Not Epub Abstract:
Rhabdomyolysis is an acute failure of cellular homeostasis resulting in muscle breakdown, triggered by trauma, infection, drugs... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Malaichamy S, Idoux R, Polavarapu K, Šikić K, Holla E, Thompson R, Spendiff S, Schänzer A, Kusters B, Freeman E, Hentschel A, O'Neil D, Carmona-Martinez R, Dobelmann V, Tucht C, Schouten M, Ruck T, Schara-Schmidt U, Kamsteeg EJ, Ramadža DP, Jakovčević A, Zigman T, Čavka M, Karcagi V, Herczegfalvi A, Laurie S, Matalonga L, Beltran S, Horvath R, Voermans N, Roos A, Barić I, Lochmüller H. Dominant rhabdomyolysis linked to a recurrent ATP2A2 variant reducing SERCA2 function in muscle. Brain. 2025 Feb 19:awaf067. doi: 10.1093/brain/awaf067. Epub ahead of print. PMID: 39970126. |