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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12092 scientific papers returned from the database with the search filters currently being used below.

Localization and function of key axonemal microtubule inner proteins and dynein docking complex members reveal extensive diversity among vertebrate motile cilia

Authors:
Roy S, Lu H, Twan WK, Ikawa Y, Khare VP, Mukherjee I, Chua KX, Chakrabarti S, Hamada H
Citation:
bioRxiv. 2024;[preprint] doi:10.1101/2024.02.14.580281
Epub:
Not Epub
Abstract:
Vertebrate motile cilia are broadly classified as (9+2) or (9+0), based on the presence or absence of the central pair...
Link:
https://www.biorxiv.org/content/10.1101/2024.02.14.580281v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Roy S, Lu H, Twan WK, Ikawa Y, Khare VP, Mukherjee I, Chua KX, Chakrabarti S, Hamada H. Localization and function of key axonemal microtubule inner proteins and dynein docking complex members reveal extensive diversity among vertebrate motile cilia. bioRxiv. 2024;[preprint] doi:10.1101/2024.02.14.580281.

Zebrafish Mbd5 binds to RNA m5C and regulates histone deubiquitylation and gene expression in development metabolism and behavior

Authors:
Guo J, Zou Z, Dou X, Zhao X, Wang Y, Wei L, Pi Y, Wang Y, He C, Guo S
Citation:
Nucleic Acids Res. 2024;[Epub]:gkae093. doi:10.1093/nar/gkae093
Epub:
Not Epub
Abstract:
Complex biological processes are regulated by both genetic and epigenetic programs. One class of epigenetic modifications is...
Link:
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkae093/7608825
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guo J, Zou Z, Dou X, Zhao X, Wang Y, Wei L, Pi Y, Wang Y, He C, Guo S. Zebrafish Mbd5 binds to RNA m5C and regulates histone deubiquitylation and gene expression in development metabolism and behavior. Nucleic Acids Res. 2024;[Epub]:gkae093. doi:10.1093/nar/gkae093.

Apela promotes blood vessel regeneration and remodeling in zebrafish

Authors:
Nys N, Khatib AM, Siegfried G
Citation:
Sci Rep. 2024 Feb 14;14(1):3718. doi: 10.1038/s41598-023-50677-1
Epub:
Not Epub
Abstract:
In contrast to adult mammals, zebrafish display a high capacity to heal injuries and repair damage to various organs. One of...
Link:
https://www.nature.com/articles/s41598-023-50677-1
Delivery Method:
microinjection, injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Nys N, Khatib AM, Siegfried G. Apela promotes blood vessel regeneration and remodeling in zebrafish. Sci Rep. 2024 Feb 14;14(1):3718. doi: 10.1038/s41598-023-50677-1.

Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm

Authors:
Luu O, Barua D, Winklbauer R
Citation:
PLoS One. 2024 Feb 12;19(2):e0297420. doi: 10.1371/journal.pone.0297420. eCollection 2024
Epub:
Not Epub
Abstract:
Convergent extension of the chordamesoderm is the best-examined gastrulation movement in Xenopus. Here we study general...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0297420
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Luu O, Barua D, Winklbauer R. Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm. PLoS One. 2024 Feb 12;19(2):e0297420. doi: 10.1371/journal.pone.0297420. eCollection 2024.

Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos

Authors:
Cairelli AG, Gendernalik A, Chan WX, Nguyen P, Vermot J, Lee J, Bark D Jr, Yap CH
Citation:
J Physiol. 2024 Feb 12. doi: 10.1113/JP285490. Online ahead of print
Epub:
Yes
Abstract:
Cardiac trabeculae are uneven ventricular muscular structures that develop during early embryonic heart development at the...
Link:
https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP285490
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cairelli AG, Gendernalik A, Chan WX, Nguyen P, Vermot J, Lee J, Bark D Jr, Yap CH. Role of tissue biomechanics in the formation and function of myocardial trabeculae in zebrafish embryos. J Physiol. 2024 Feb 12. doi: 10.1113/JP285490. Online ahead of print.

An alternative strategy to increasing influenza virus replication for vaccine production in chicken embryo fibroblast (DF-1) cells by inhibiting interferon alpha and beta using peptide-conjugated phosphorodiamidate morpholino oligomers

Authors:
Prescott MA, Moulton H, Pastey MK
Citation:
J Med Microbiol. 2024 Feb;73(2). doi: 10.1099/jmm.0.001807
Epub:
Not Epub
Abstract:
Introduction. Influenza is a global health issue causing substantial health and economic burdens on affected populations....
Link:
https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.001807
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: DF-1 chick embryo fibroblasts
Citation Extract:
Prescott MA, Moulton H, Pastey MK. An alternative strategy to increasing influenza virus replication for vaccine production in chicken embryo fibroblast (DF-1) cells by inhibiting interferon alpha and beta using peptide-conjugated phosphorodiamidate morpholino oligomers. J Med Microbiol. 2024 Feb;73(2). doi: 10.1099/jmm.0.001807.

Comprehensive analysis of diel rhythmic expression of the medaka toll-like receptor gene family

Authors:
Hata T, Shimawaki H, Setoguchi S, Morimoto N, Hikima J-i, Sakai M, Kono T
Citation:
Dev Comp Immunol. 2024;[Epub] doi:10.1016/j.dci.2024.105143
Epub:
Not Epub
Abstract:
Several immune-related genes, including Toll-like receptors (TLR), are associated with circadian rhythms in mammals. However,...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0145305X24000156
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Hata T, Shimawaki H, Setoguchi S, Morimoto N, Hikima J-i, Sakai M, Kono T. Comprehensive analysis of diel rhythmic expression of the medaka toll-like receptor gene family. Dev Comp Immunol. 2024;[Epub] doi:10.1016/j.dci.2024.105143.

Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance

Authors:
Pucci G, Minafra L, Bravatà V, Calvaruso M, Turturici G, Cammarata FP, Savoca G, Abbate B, Russo G, Cavalieri V, Forte GI
Citation:
Int J Mol Sci. 2024;25(4):2079; doi:10.3390/ijms25042079
Epub:
Not Epub
Abstract:
The hypoxic pattern of glioblastoma (GBM) is known to be a primary cause of radioresistance. Our study explored the possibility...
Link:
https://www.mdpi.com/1422-0067/25/4/2079
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: U87 human glioblastoma
Citation Extract:
Pucci G, Minafra L, Bravatà V, Calvaruso M, Turturici G, Cammarata FP, Savoca G, Abbate B, Russo G, Cavalieri V, Forte GI. Glut-3 Gene Knockdown as a Potential Strategy to Overcome Glioblastoma Radioresistance. Int J Mol Sci. 2024;25(4):2079; doi:10.3390/ijms25042079.

Znf687 recruits Brd4-Smrt complex to regulate gfi1aa during neutrophil development

Authors:
Yan L, Tan S, Wang H, Yuan H, Liu X, Chen Y, de Thé H, Zhu J, Zhou J
Citation:
Leukemia. 2024;[Epub] doi:10.1038/s41375-024-02165-2
Epub:
Not Epub
Abstract:
Neutrophils are key component of the innate immune system in vertebrates. Diverse transcription factors and cofactors act in a...
Link:
https://www.nature.com/articles/s41375-024-02165-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yan L, Tan S, Wang H, Yuan H, Liu X, Chen Y, de Thé H, Zhu J, Zhou J. Znf687 recruits Brd4-Smrt complex to regulate gfi1aa during neutrophil development. Leukemia. 2024;[Epub] doi:10.1038/s41375-024-02165-2.

Analysis of SMAD1/5 target genes in a sea anemone reveals ZSWIM4-6 as a novel BMP signaling modulator

Authors:
Knabl P, Schauer A, Pomreinke AP, Zimmermann B, Rogers KW, Čapek D, Müller P, Genikhovich G
Citation:
Elife. 2024 Feb 7;13:e80803. doi: 10.7554/eLife.80803
Epub:
Not Epub
Abstract:
BMP signaling has a conserved function in patterning the dorsal-ventral body axis in Bilateria and the directive axis in...
Link:
https://elifesciences.org/articles/80803
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Knabl P, Schauer A, Pomreinke AP, Zimmermann B, Rogers KW, Čapek D, Müller P, Genikhovich G. Analysis of SMAD1/5 target genes in a sea anemone reveals ZSWIM4-6 as a novel BMP signaling modulator. Elife. 2024 Feb 7;13:e80803. doi: 10.7554/eLife.80803.

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