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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9382 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka

Authors:
Herpin A, Schmidt C, Kneitz S, Gobé C, Regensburger M, Le Cam A, Montfort J, Adolfi MC, Lillesaar C, Wilhelm D, Kraeussling M, Mourot B, Porcon B, Pannetier M, Pailhoux E, Ettwiller L, Dolle D, Guiguen Y, Schartl M
Citation:
PLoS Biol. 2019;17(4):e3000185. https://doi.org/10.1371/journal.pbio.3000185
Abstract:
Dmrt1 is a highly conserved transcription factor, which is critically involved in regulation of gonad development of...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Herpin A, Schmidt C, Kneitz S, Gobé C, Regensburger M, Le Cam A, Montfort J, Adolfi MC, Lillesaar C, Wilhelm D, Kraeussling M, Mourot B, Porcon B, Pannetier M, Pailhoux E, Ettwiller L, Dolle D, Guiguen Y, Schartl M. A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka. PLoS Biol. 2019;17(4):e3000185. https://doi.org/10.1371/journal.pbio.3000185.

The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo

Authors:
Laue K, Rajshekar S, Courtney AJ, Lewis ZA, Goll MG
Citation:
Nat Comm. 2019;10(1):1551. doi:10.1038/s41467-019-09582-3
Abstract:
The segregation of eukaryotic genomes into euchromatin and heterochromatin represents a fundamental and poorly understood...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Laue K, Rajshekar S, Courtney AJ, Lewis ZA, Goll MG. The maternal to zygotic transition regulates genome-wide heterochromatin establishment in the zebrafish embryo. Nat Comm. 2019;10(1):1551. doi:10.1038/s41467-019-09582-3.

In vivo topology converts competition for cell-matrix adhesion into directional migration

Authors:
Bajanca F, Gouignard N, Colle C, Parsons M, Mayor R, Theveneau E
Citation:
Nat Comm. 2019;10(1):1518. doi:10.1038/s41467-019-09548-5
Abstract:
When migrating in vivo, cells are exposed to numerous conflicting signals: chemokines, repellents, extracellular matrix, growth...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bajanca F, Gouignard N, Colle C, Parsons M, Mayor R, Theveneau E. In vivo topology converts competition for cell-matrix adhesion into directional migration. Nat Comm. 2019;10(1):1518. doi:10.1038/s41467-019-09548-5.

PTC-bearing mRNA elicits a genetic compensation response via Upf3a and COMPASS components

Authors:
Ma Z, Zhu P, Shi H, Guo L, Zhang Q, Chen Y, Chen S, Zhang Z, Peng J, Chen J
Citation:
Nature. 2019;[Epub ahead of print] doi:10.1038/s41586-019-1057-y
Abstract:
The genetic compensation response (GCR) has recently been proposed as a possible explanation for the phenotypic discrepancies...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma Z, Zhu P, Shi H, Guo L, Zhang Q, Chen Y, Chen S, Zhang Z, Peng J, Chen J. PTC-bearing mRNA elicits a genetic compensation response via Upf3a and COMPASS components. Nature. 2019;[Epub ahead of print] doi:10.1038/s41586-019-1057-y.

The Neuromodulator Adenosine Regulates Oligodendrocyte Migration at Motor Exit Point Transition Zones

Authors:
Fontenas L, Welsh TG, Piller M, Coughenour P, Gandhi AV, Prober DA, Kucenas S
Citation:
Cell Rep. 2019;27(1):115-128.E5 doi:10.1016/j.celrep.2019.03.013
Abstract:
During development, oligodendrocyte progenitor cells (OPCs) migrate extensively throughout the spinal cord. However, their...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fontenas L, Welsh TG, Piller M, Coughenour P, Gandhi AV, Prober DA, Kucenas S. The Neuromodulator Adenosine Regulates Oligodendrocyte Migration at Motor Exit Point Transition Zones. Cell Rep. 2019;27(1):115-128.E5 doi:10.1016/j.celrep.2019.03.013.

Zebrafish Klf4 maintains the ionocyte progenitor population by regulating epidermal stem cell proliferation and lateral inhibition

Authors:
Chen Y-C, Liao B-K, Lu Y-F, Liu Y-H, Hsieh F-C, Hwang P-P, Hwang S-PL
Citation:
PLoS Genet. 2019;15(4):e1008058. doi:10.1371/journal.pgen.1008058
Abstract:
In the skin and gill epidermis of fish, ionocytes develop alongside keratinocytes and maintain body fluid ionic homeostasis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chen Y-C, Liao B-K, Lu Y-F, Liu Y-H, Hsieh F-C, Hwang P-P, Hwang S-PL. Zebrafish Klf4 maintains the ionocyte progenitor population by regulating epidermal stem cell proliferation and lateral inhibition. PLoS Genet. 2019;15(4):e1008058. doi:10.1371/journal.pgen.1008058.

Inhibition of Neogenin Promotes Neuronal Survival and Improved Behavior Recovery after Spinal Cord Injury

Authors:
Chen J, Shifman MI
Citation:
Neuroscience. 2019;[Epub ahead of print] doi:10.1016/j.neuroscience.2019.03.055
Abstract:
Following spinal cord trauma, axonal regeneration in the mammalian spinal cord do not occur and functional recovery may be...
Organism or Cell Type:
lamprey
Citation Extract:
Chen J, Shifman MI. Inhibition of Neogenin Promotes Neuronal Survival and Improved Behavior Recovery after Spinal Cord Injury. Neuroscience. 2019;[Epub ahead of print] doi:10.1016/j.neuroscience.2019.03.055.

Time Space Translation: A Confirmed Primary Axial Patterning Mechanism in Vertebrates

Authors:
Durston AJ
Citation:
Preprints. 2019:2019030262 [preprint]
Abstract:
The vertebrate anterior-posterior (A-P) body axis arises due to time space translation (TST). BMP dependent Hox temporal...
Organism or Cell Type:
Xenopus
Citation Extract:
Durston AJ. Time Space Translation: A Confirmed Primary Axial Patterning Mechanism in Vertebrates. Preprints. 2019:2019030262 [preprint] .

A U2-snRNP-independent role of SF3b in promoting mRNA export

Authors:
Wang K, Yin C, Du X, Chen S, Wang J, Zhang L, Wang L, Yu Y, Chi B, Shi M, Wang C, Reed R, Zhou Y, Huang J, Cheng H
Citation:
Proc Natl Acad Sci USA. 2019;116(16):7837-46. doi:10.1073/pnas.1818835116
Abstract:
To ensure efficient and accurate gene expression, pre-mRNA processing and mRNA export need to be balanced. However, how this...
Delivery Method:
microinjection
Organism or Cell Type:
cell culture
Citation Extract:
Wang K, Yin C, Du X, Chen S, Wang J, Zhang L, Wang L, Yu Y, Chi B, Shi M, Wang C, Reed R, Zhou Y, Huang J, Cheng H. A U2-snRNP-independent role of SF3b in promoting mRNA export. Proc Natl Acad Sci USA. 2019;116(16):7837-46. doi:10.1073/pnas.1818835116 .

Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis

Authors:
Yokote N, Suzuki-Kosaka MY, Michiue T, Hara T, Tanegashima K
Citation:
Int J Dev Biol. 2019;63(1-2):29-35. doi: 10.1387/ijdb.180184kt
Abstract:
Latrophilin2 (Lphn2) is an adhesion-class of G protein-coupled receptor with an unknown function in development. Here, we show...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yokote N, Suzuki-Kosaka MY, Michiue T, Hara T, Tanegashima K. Latrophilin2 is involved in neural crest cell migration and placode patterning in Xenopus laevis. Int J Dev Biol. 2019;63(1-2):29-35. doi: 10.1387/ijdb.180184kt.

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