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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 11902 scientific papers returned from the database with the search filters currently being used below.
There are 11902 scientific papers returned from the database with the search filters currently being used below.
Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome
Citation:
Hum Genet Genom Adv. 2023;4(4):100232. doi:10.1016/j.xhgg.2023.100232 Epub:
Not Epub Abstract:
Hypoplastic left heart syndrome (HLHS) is a severe congenital heart defect (CHD) characterized by hypoplasia of the left... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Blue EE, White JJ, Dush MK, Gordon WW, Wyatt BH, White P, Marvin CT, Helle E, Ojala T, Priest JR, Jenkins MM, Almli LM, Reefhuis J, Pangilinan F, Brody LC, McBride KL, Garg V, Shaw GM, Romitti PA, Nembhard WN, Browne ML, Werler MM, Kay DM, Mital S, Chong JX, Nascone-Yoder NM, Bamshad MJ
. Rare variants in CAPN2 increase risk for isolated hypoplastic left heart syndrome. Hum Genet Genom Adv. 2023;4(4):100232. doi:10.1016/j.xhgg.2023.100232. |
Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy
Citation:
J Clin Invest. 2023 Jul 25:e166275. doi: 10.1172/JCI166275. Online ahead of print Epub:
Yes Abstract:
X-linked myotubular myopathy (XLMTM) is a fatal congenital disorder caused by mutations in the MTM1 gene. Currently, there are... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Karolczak S, Deshwar AR, Aristegui E, Kamath BM, Lawlor MW, Andreoletti G, Volpatti JR, Ellis JL, Yin C, Dowling JJ. Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy. J Clin Invest. 2023 Jul 25:e166275. doi: 10.1172/JCI166275. Online ahead of print. |
Paracrine regulation of neural crest EMT by placodal MMP28
Citation:
PLoS Biol. 2023 Aug 17;21(8):e3002261. doi: 10.1371/journal.pbio.3002261. Online ahead of print Epub:
Not Epub Abstract:
Epithelial–mesenchymal transition (EMT) is an early event in cell dissemination from epithelial tissues. EMT endows cells with... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Gouignard N, Bibonne A, Mata JF, Bajanca F, Berki B, Barriga EH, Saint-Jeannet JP, Theveneau E. Paracrine regulation of neural crest EMT by placodal MMP28. PLoS Biol. 2023 Aug 17;21(8):e3002261. doi: 10.1371/journal.pbio.3002261. Online ahead of print. |
“Plod2” a Lysyl Hydroxylase Required for HSC Specification
Citation:
Exp. Hematol. 2023;124 supplement:S101. doi:10.1016/j.exphem.2023.06.209 Epub:
Not Epub Abstract:
Hematopoietic stem cells (HSCs) are self-renewing precursors that continuously renew hematopoietic lineages during life and... Organism or Cell Type:
zebrafish Citation Extract: Khoury H, Clements W. “Plod2” a Lysyl Hydroxylase Required for HSC Specification. Exp. Hematol. 2023;124 supplement:S101. doi:10.1016/j.exphem.2023.06.209. |
Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons
Citation:
Commun Biol. 2023 Aug 15;6(1):849. doi: 10.1038/s42003-023-05223-0 Epub:
Not Epub Abstract:
Understanding the molecular interaction between ligand and receptor is important for providing the basis for the development of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fu CY, Chen HY, Lin CY, Chen SJ, Sheu JC, Tsai HJ. Extracellular Pgk1 interacts neural membrane protein enolase-2 to improve the neurite outgrowth of motor neurons. Commun Biol. 2023 Aug 15;6(1):849. doi: 10.1038/s42003-023-05223-0. |
Ontogenetically distinct neutrophils differ in function and transcriptional profile in zebrafish
Citation:
Nat Commun. 2023 Aug 15;14(1):4942. doi: 10.1038/s41467-023-40662-7 Epub:
Not Epub Abstract:
The current view of hematopoiesis considers leukocytes on a continuum with distinct developmental origins, and which exert non-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: García-López JP, Grimaldi A, Chen Z, Meneses C, Bravo-Tello K, Bresciani E, Banderas A, Burgess SM, Hernández PP, Feijoo CG. Ontogenetically distinct neutrophils differ in function and transcriptional profile in zebrafish. Nat Commun. 2023 Aug 15;14(1):4942. doi: 10.1038/s41467-023-40662-7. |
Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.08.14.553249 Epub:
Not Epub Abstract:
During heart development, the embryonic ventricle becomes enveloped by the epicardium, a layer of mesothelium which adheres to... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Pollitt EJG, Derrick CJ, Sánchez-Posada J, Noël ES. Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle. bioRxiv. 2023;[preprint] doi:10.1101/2023.08.14.553249. |
Lymphocyte pathway analysis using naturally lymphocyte-deficient fish
Citation:
Eur J Immunol. 2023 Aug 18:e2350577. doi: 10.1002/eji.202350577. Online ahead of print Epub:
Yes Abstract:
Comparative phylogenetic analyses are of potential value to establish the essential components of genetic networks underlying... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang G, Swann J, Felder M, O'Meara C, Boehm T. Lymphocyte pathway analysis using naturally lymphocyte-deficient fish. Eur J Immunol. 2023 Aug 18:e2350577. doi: 10.1002/eji.202350577. Online ahead of print. |
Alternative splicing of its 5’-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies
Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.02.19.529123 Epub:
Not Epub Abstract:
Aberrant skipping of coding exons in CD19 and CD22 compromises responses to immunotherapy for B-cell malignancies. Here, we... Delivery Method:
Electroporation, Vivo-Morpholino Organism or Cell Type:
cell culture: Raji, OCI-Ly8, and MEC-1 cells Citation Extract: Ang Z, Paruzzo L, Hayer KE, Schmidt C, Diz MT, Xu F, Zankharia U, Zhang Y, Soldan S, Zheng S, Falkenstein CD, Loftus JP, Yang SY, Mukta Asnani, Sainos PK, Pillai V, Chong E, Li MM, Tasian SK, Barash Y, Lieberman PM, Ruella M, Schuster SJ, Thomas-Tikhonenko A. Alternative splicing of its 5’-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. bioRxiv. 2023;[preprint] doi:10.1101/2023.02.19.529123 . |
Sequence specificity defines the effectiveness of PPMOs targeting Pseudomonas aeruginosa
Citation:
Antimicrob Agents Chemother. 2023 Aug 23:e0024523. doi: 10.1128/aac.00245-23. Online ahead of print Epub:
Yes Abstract:
Development of new therapeutics against antibiotic resistant pathogenic bacteria is recognized as a priority across the globe.... Delivery Method:
peptide-linked Organism or Cell Type:
Pseudomonas aeruginosa (bacterium) Citation Extract: Nanayakkara AK, Moustafa DA, Pifer R, Goldberg JB, Greenberg DE. Sequence specificity defines the effectiveness of PPMOs targeting Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2023 Aug 23:e0024523. doi: 10.1128/aac.00245-23. Online ahead of print. |