You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9646 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

miR-301a Regulates Inflammatory Response to Japanese Encephalitis Virus Infection via Suppression of NKRF Activity

Authors:
Hazra B, Chakraborty S, Bhaskar M, Mukherjee S, Mahadevan A, Basu A
Citation:
J Immunol. 2019;[Epub ahead of pint] doi:10.4049/jimmunol.1900003
Abstract:
Microglia being the resident macrophage of brain provides neuroprotection following diverse microbial infections. Japanese...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Hazra B, Chakraborty S, Bhaskar M, Mukherjee S, Mahadevan A, Basu A. miR-301a Regulates Inflammatory Response to Japanese Encephalitis Virus Infection via Suppression of NKRF Activity. J Immunol. 2019;[Epub ahead of pint] doi:10.4049/jimmunol.1900003.

ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) deficient zebrafish cause temporal fin development and regeneration defects

Authors:
Liedtke D, Orth M, Meissler M, Geuer S, Knaup S, Köblitz I, Klopocki E
Citation:
Sci Rep. 2019;9(1):13383. doi:10.1038/s41598-019-50055-w
Abstract:
Fin development and regeneration are complex biological processes that are highly relevant in teleost fish. They share genetic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liedtke D, Orth M, Meissler M, Geuer S, Knaup S, Köblitz I, Klopocki E. ECM alterations in Fndc3a (Fibronectin Domain Containing Protein 3A) deficient zebrafish cause temporal fin development and regeneration defects. Sci Rep. 2019;9(1):13383. doi:10.1038/s41598-019-50055-w.

Identification of ATP synthase α subunit as a new maternal factor capable of protecting zebrafish embryos from bacterial infection

Authors:
Ni S, Zhou Y, Chen Y, Du X, Zhang S
Citation:
FASEB J. 2019 Sep 13:fj201901290R. doi: 10.1096/fj.201901290R. [Epub ahead of print]
Abstract:
Previous studies have shown that ATP synthase α subunit (ATP5A1) plays multiple roles, but our understanding of its biologic...
Organism or Cell Type:
zebrafish
Citation Extract:
Ni S, Zhou Y, Chen Y, Du X, Zhang S. Identification of ATP synthase α subunit as a new maternal factor capable of protecting zebrafish embryos from bacterial infection. FASEB J. 2019 Sep 13:fj201901290R. doi: 10.1096/fj.201901290R. [Epub ahead of print].

Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2−/− mice

Authors:
Vik Meadows V, Kennedy L, Hargrove L, Demieville J, Meng F, Virani S, Reinhart E, Kyritsi K, Invernizzi P, Yang Z, Wu N, Liangpunsakul S, Alpini G, Francis H
Citation:
Biochem Biophys Acta. 2019;[Epub ahead of print] doi:10.1016/j.bbadis.2019.165557
Abstract:
Abstract: Primary sclerosing cholangitis (PSC) is characterized by increased mast cell (MC) infiltration, biliary damage and...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Vik Meadows V, Kennedy L, Hargrove L, Demieville J, Meng F, Virani S, Reinhart E, Kyritsi K, Invernizzi P, Yang Z, Wu N, Liangpunsakul S, Alpini G, Francis H. Downregulation of hepatic stem cell factor by Vivo-Morpholino treatment inhibits mast cell migration and decreases biliary damage/senescence and liver fibrosis in Mdr2−/− mice. Biochem Biophys Acta. 2019;[Epub ahead of print] doi:10.1016/j.bbadis.2019.165557.

A Complex of U1 snRNP with Cleavage and Polyadenylation Factors Controls Telescripting, Regulating mRNA Transcription in Human Cells

Authors:
So BR, Di C, Cai Z, Oh J-M, Arai C, Dreyfuss G
Citation:
Molec Cell. 2019;[Epub ahead of print] doi:10.1016/j.molcel.2019.08.007
Abstract:
Full-length transcription in the majority of human genes depends on U1 snRNP (U1) to co-transcriptionally suppress...
Citation Extract:
So BR, Di C, Cai Z, Oh J-M, Arai C, Dreyfuss G. A Complex of U1 snRNP with Cleavage and Polyadenylation Factors Controls Telescripting, Regulating mRNA Transcription in Human Cells. Molec Cell. 2019;[Epub ahead of print] doi:10.1016/j.molcel.2019.08.007.

Multisystem analyses of two Cockayne syndrome associated proteins CSA and CSB reveal shared and unique functions

Authors:
Wu Z, Yua Q, Zhu X, Xu Y, Wang Y
Citation:
DNA Repair. 2019;[Epub ahead of print] doi:10.1016/j.dnarep.2019.102696
Abstract:
Mutations in the CSA and CSB genes are causative of Cockayne syndrome neurological disorder. Since the identification of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wu Z, Yua Q, Zhu X, Xu Y, Wang Y. Multisystem analyses of two Cockayne syndrome associated proteins CSA and CSB reveal shared and unique functions. DNA Repair. 2019;[Epub ahead of print] doi:10.1016/j.dnarep.2019.102696.

BACE1 Inhibition Using 2’-OMePS Steric Blocking Antisense Oligonucleotides

Authors:
Chakravarthy M, Veedu RN
Citation:
Genes. 2019:10(9):705. doi:10.3390/genes10090705
Abstract:
Amyloid beta-peptide is produced by the cleavage of amyloid precursor protein by two secretases, a β-secretase, beta-site...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: HEK293
Citation Extract:
Chakravarthy M, Veedu RN. BACE1 Inhibition Using 2’-OMePS Steric Blocking Antisense Oligonucleotides. Genes. 2019:10(9):705. doi:10.3390/genes10090705.

Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2−/− mouse model of primary sclerosing cholangitis (PSC)

Authors:
Zhou T, Kyritsi K, Wu N, Francis H, Yang Z, Chen L, O'Brien A, Kennedy L, Ceci L, Meadows V, Kusumanchi P, Wu C, Baiocchi L, Skill NJ, Saxena R, Sybenga A, Xie L, Liangpunsakul S, Meng F, Alpini G, Glaser S
Citation:
EBioMedicine, 2019;[in press] doi:10.1016/j.ebiom.2019.09.013
Abstract:
Background: Cholangiocytes are the target cells of cholangiopathies including primary sclerosing cholangitis (PSC). Vimentin is...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Zhou T, Kyritsi K, Wu N, Francis H, Yang Z, Chen L, O'Brien A, Kennedy L, Ceci L, Meadows V, Kusumanchi P, Wu C, Baiocchi L, Skill NJ, Saxena R, Sybenga A, Xie L, Liangpunsakul S, Meng F, Alpini G, Glaser S. Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2−/− mouse model of primary sclerosing cholangitis (PSC). EBioMedicine, 2019;[in press] doi:10.1016/j.ebiom.2019.09.013.

Sonic Hedgehog repression underlies gigaxonin mutation-induced motor deficits in giant axonal neuropathy

Authors:
Arribat Y, Mysiak KS, Lescouzères L, Boizot A, Ruiz M, Rossel M, Bomont P
Citation:
J Clin Invest. 2019;{Epub ahead of print] doi:10.1172/JCI129788
Abstract:
Growing evidence shows that alterations occurring at early developmental stages contribute to symptoms manifested in adulthood...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Arribat Y, Mysiak KS, Lescouzères L, Boizot A, Ruiz M, Rossel M, Bomont P. Sonic Hedgehog repression underlies gigaxonin mutation-induced motor deficits in giant axonal neuropathy. J Clin Invest. 2019;{Epub ahead of print] doi:10.1172/JCI129788.

Biomechanical signaling within the developing zebrafish heart attunes endocardial growth to myocardial chamber dimensions

Authors:
Bornhorst D, Xia P, Nakajima H, Dingare C, Herzog W, Lecaudey V, Mochizuki N, Heisenberg C-P, Yelon D, Abdelilah-Seyfried S
Citation:
Nat Comm. 2019;10(1):4113. doi:10.1038/s41467-019-12068-x
Abstract:
Intra-organ communication guides morphogenetic processes that are essential for an organ to carry out complex physiological...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bornhorst D, Xia P, Nakajima H, Dingare C, Herzog W, Lecaudey V, Mochizuki N, Heisenberg C-P, Yelon D, Abdelilah-Seyfried S. Biomechanical signaling within the developing zebrafish heart attunes endocardial growth to myocardial chamber dimensions. Nat Comm. 2019;10(1):4113. doi:10.1038/s41467-019-12068-x.

Pages