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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9561 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia

Authors:
McLennan R, McKinney MC, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Ridenour DA, Manthe CA, Giniunaite R, Robinson M, Baker RE, Maini PK, Kulesa PM
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/719666
Abstract:
Neural crest migration requires cells to move through an environment filled with dense extracellular matrix and mesoderm to...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McLennan R, McKinney MC, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Ridenour DA, Manthe CA, Giniunaite R, Robinson M, Baker RE, Maini PK, Kulesa PM. Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia. bioRxiv. 2019:[preprint] doi:10.1101/719666.

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence

Authors:
Torraca V, Kaforou M, Watson J, Duggan GM, Guerrero-Gutierrez H, Krokowski S, Hollinshead M, Thomas B. Clarke TB, Mostowy RJ, Tomlinson GS, Sancho-Shimizu V, Clements A, Mostowy S
Citation:
BioRxiv. 2019:[preprint] doi:10.1101/719781
Abstract:
Shigella flexneri is historically regarded as the primary agent of bacillary dysentery, yet the closely-related Shigella sonnei...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Torraca V, Kaforou M, Watson J, Duggan GM, Guerrero-Gutierrez H, Krokowski S, Hollinshead M, Thomas B. Clarke TB, Mostowy RJ, Tomlinson GS, Sancho-Shimizu V, Clements A, Mostowy S. Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence. BioRxiv. 2019:[preprint] doi:10.1101/719781.

Early expression of Tubulin Beta-III in avian cranial neural crest cells

Authors:
Chacon J, Rogers CD
Citation:
Gene Expr Patt. 2019;[Epub ahead of print] doi:10.1016/j.gep.2019.119067
Abstract:
Neural crest cells are a transient stem-like cell population that forms in the dorsal neural tube of vertebrate embryos and...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Chacon J, Rogers CD. Early expression of Tubulin Beta-III in avian cranial neural crest cells. Gene Expr Patt. 2019;[Epub ahead of print] doi:10.1016/j.gep.2019.119067.

THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis

Authors:
Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/719823
Abstract:
Apoptosis of cochlear hair cells is a key step towards age-related hearing loss. Although numerous genes have been implicated...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D. THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis. bioRxiv. 2019;[preprint] doi:10.1101/719823 .

Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas

Authors:
Hoang T, Wang J, Boyd P, Wang F, Santiago C, Jiang L, Lahne M, Todd L, Saez C, Yoo S, Keuthan C, Palazzo I, Squires N, Campbell W, Jia M, Rajaii F, Parayil T, Wang G, Ash J, Fischer A, Hyde D, Qian J, Blackshaw S
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/717876
Abstract:
Injury induces retinal Muller glia of cold-blooded, but not mammalian, vertebrates to generate neurons. To identify gene...
Delivery Method:
intravitreal injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Hoang T, Wang J, Boyd P, Wang F, Santiago C, Jiang L, Lahne M, Todd L, Saez C, Yoo S, Keuthan C, Palazzo I, Squires N, Campbell W, Jia M, Rajaii F, Parayil T, Wang G, Ash J, Fischer A, Hyde D, Qian J, Blackshaw S. Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas. bioRxiv. 2019:[preprint] doi:10.1101/717876 .

Therapeutic Silencing of Centromere Protein X Ameliorates Hyperglycemia in Zebrafish and Mouse Models of Type 2 Diabetes Mellitus

Authors:
Zang L, Shimada Y, Nakayama H, Chen W, Okamoto A, Koide H, Oku N, Dewa T, Shiota M, Nishimura N
Citation:
Front Genet. 2019;10:693. doi:10.3389/fgene.2019.00693
Abstract:
Type 2 diabetes mellitus (T2DM) is characterized by persistent hyperglycemia and is influenced by genetic and environmental...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Zang L, Shimada Y, Nakayama H, Chen W, Okamoto A, Koide H, Oku N, Dewa T, Shiota M, Nishimura N. Therapeutic Silencing of Centromere Protein X Ameliorates Hyperglycemia in Zebrafish and Mouse Models of Type 2 Diabetes Mellitus. Front Genet. 2019;10:693. doi:10.3389/fgene.2019.00693.

FoxH1 represses miR-430 during early embryonic development of zebrafish via non-canonical regulation

Authors:
Fischer P, Chen H, Pacho F, Rieder D, Kimmel RA, Meyer D
Citation:
BMC Biol. 2019 Jul 30;17(1):61. doi: 10.1186/s12915-019-0683-z
Abstract:
BACKGROUND: FoxH1 is a forkhead transcription factor with conserved key functions in vertebrate mesoderm induction and left-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fischer P, Chen H, Pacho F, Rieder D, Kimmel RA, Meyer D. FoxH1 represses miR-430 during early embryonic development of zebrafish via non-canonical regulation. BMC Biol. 2019 Jul 30;17(1):61. doi: 10.1186/s12915-019-0683-z.

TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis

Authors:
Ogata S, Morokuma J, Hayata T, Kolle G, Niehrs C, Ueno N, Cho KW
Citation:
Genes Dev. 2007 Jul 15;21(14):1817-31
Abstract:
The molecular mechanisms governing the cell behaviors underlying morphogenesis remain a major focus of research in both...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ogata S, Morokuma J, Hayata T, Kolle G, Niehrs C, Ueno N, Cho KW. TGF-beta signaling-mediated morphogenesis: modulation of cell adhesion via cadherin endocytosis. Genes Dev. 2007 Jul 15;21(14):1817-31.

Ability of prebiotic polysaccharides to activate a HIF1α-antimicrobial peptide axis determines liver injury risk in zebrafish

Authors:
Zhang Z, Ran C, Ding Q-w, Liu H-l, Xie M-x, Yang Y-l, Ya-dong Xie Y-d, Gao C-c, Zhang H-l, Zhou Z-g
Citation:
Comm Biol. 2019;2(1):274. doi:10.1038/s42003-019-0526-z
Abstract:
Natural polysaccharides have received much attention for their ability to ameliorate hepatic steatosis induced by high-fat diet...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Z, Ran C, Ding Q-w, Liu H-l, Xie M-x, Yang Y-l, Ya-dong Xie Y-d, Gao C-c, Zhang H-l, Zhou Z-g. Ability of prebiotic polysaccharides to activate a HIF1α-antimicrobial peptide axis determines liver injury risk in zebrafish. Comm Biol. 2019;2(1):274. doi:10.1038/s42003-019-0526-z.

Evolution and Developmental Diversity of Skin Spines in Pufferfishes

Authors:
Shono T, Thiery AP, Cooper RL, Kurokawa D, Britz R, Okabe M, Fraser GJ
Citation:
iScience. 2019 Jun 19. pii: S2589-0042(19)30185-3. doi: 10.1016/j.isci.2019.06.003. [Epub ahead of print]
Abstract:
Teleost fishes develop remarkable varieties of skin ornaments. The developmental basis of these structures is poorly understood...
Delivery Method:
microinjection
Organism or Cell Type:
Takifugu niphobles (pufferfish)
Citation Extract:
Shono T, Thiery AP, Cooper RL, Kurokawa D, Britz R, Okabe M, Fraser GJ. Evolution and Developmental Diversity of Skin Spines in Pufferfishes. iScience. 2019 Jun 19. pii: S2589-0042(19)30185-3. doi: 10.1016/j.isci.2019.06.003. [Epub ahead of print].

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