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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9320 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

A zebrafish model for MonoMAC syndrome identifies an earlier role for gata2 in haemogenic endothelium programming and generation of haematopoietic stem cells

Authors:
Dobrzycki T, Krecsmarik M, Koyunlar C, Rispoli R, Peulen-Zink J, Gussinklo K, de Pater E, Patient R, Monteiro R
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/516203
Abstract:
Haematopoietic stem and progenitor cells (HSPCs) maintain the vertebrate blood system throughout life and their emergence from...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dobrzycki T, Krecsmarik M, Koyunlar C, Rispoli R, Peulen-Zink J, Gussinklo K, de Pater E, Patient R, Monteiro R. A zebrafish model for MonoMAC syndrome identifies an earlier role for gata2 in haemogenic endothelium programming and generation of haematopoietic stem cells. bioRxiv. 2019;[Preprint] doi:10.1101/516203.

A contractile acto-myosin belt promotes growth anisotropy during the early stages of pectoral fin development in zebrafish

Authors:
Kardash E, Nguyen H, Behrndt M, Heisenberg C-P, Peyrieras N, Gonzalez-Gaitan M
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/512038
Abstract:
The zebrafish pectoral fin is an in vivo model for vertebrate limb formation, well suited to investigate the integration of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kardash E, Nguyen H, Behrndt M, Heisenberg C-P, Peyrieras N, Gonzalez-Gaitan M. A contractile acto-myosin belt promotes growth anisotropy during the early stages of pectoral fin development in zebrafish. bioRxiv. 2019;[Preprint] doi:10.1101/512038.

Delta/Notch signaling controls neuroepithelial morphogenesis in the zebrafish spinal cord

Authors:
Sharma P, Saraswathy VM, Xiang L, Fürthauer M
Citation:
bioRxiv. 2019:[Preprint] doi:10.1101/517714
Abstract:
The morphogenesis of the nervous system requires coordinating the specification and differentiation of neural precursor cells...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sharma P, Saraswathy VM, Xiang L, Fürthauer M. Delta/Notch signaling controls neuroepithelial morphogenesis in the zebrafish spinal cord. bioRxiv. 2019:[Preprint] doi:10.1101/517714.

Piezo1 is required for outflow tract and aortic valve development

Authors:
Faucherre A, ou Maati HM, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Beroud GC, Avierinos JF, Lebon G, Zaffran S, Jopling C
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/528588
Abstract:
Aims: During embryogenesis, the onset of circulatory blood flow generates a variety of hemodynamic forces which reciprocally...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Faucherre A, ou Maati HM, Nasr N, Pinard A, Theron A, Odelin G, Desvignes JP, Salgado D, Beroud GC, Avierinos JF, Lebon G, Zaffran S, Jopling C. Piezo1 is required for outflow tract and aortic valve development. bioRxiv. 2019;[Preprint] doi:10.1101/528588.

CFTR Protects against Mycobacterium abscessus Infection by Fine-Tuning Host Oxidative Defenses

Authors:
Bernut A, Dupont C, Ogryzko NV, Neyret A, Herrmann J-L, Floto RA, Renshaw SA, Kremer L
Citation:
Cell Rep. 2019;26(7):1828-40. doi:10.1016/j.celrep.2019.01.071
Abstract:
Infection by rapidly growing Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF), a genetic disease...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bernut A, Dupont C, Ogryzko NV, Neyret A, Herrmann J-L, Floto RA, Renshaw SA, Kremer L. CFTR Protects against Mycobacterium abscessus Infection by Fine-Tuning Host Oxidative Defenses. Cell Rep. 2019;26(7):1828-40. doi:10.1016/j.celrep.2019.01.071.

Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate

Authors:
Araya C, Häkkinen H-M, Carcamo L, Cerda M, Savy T, Rookyard C, Peyriéras N, Clarke JDW
Citation:
Sci Rep. 2019;9:1835. doi:10.1038/s41598-018-38455-w
Abstract:
Tissue internalisation is a key morphogenetic mechanism by which embryonic tissues generate complex internal organs and a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Araya C, Häkkinen H-M, Carcamo L, Cerda M, Savy T, Rookyard C, Peyriéras N, Clarke JDW. Cdh2 coordinates Myosin-II dependent internalisation of the zebrafish neural plate. Sci Rep. 2019;9:1835. doi:10.1038/s41598-018-38455-w.

Novel mutations of AXIN2 identified in a Chinese Congenital Heart Disease Cohort

Authors:
Zhu M-J, Ma X-Y, Ding P-C, Tang H-F, Peng R, Lu L, Li P-Q, Qiao B, Yang X-Y, Zheng Y-F, Wang H-Y, Gao Y-Q, Chen F-S
Citation:
J Hum Genet. 2019;[Epub ahead of print] doi:10.1038/s10038-019-0572-x
Abstract:
Congenital heart defects (CHDs), the most common congenital human birth anomalies, involves complex genetic factors. Wnt/β-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhu M-J, Ma X-Y, Ding P-C, Tang H-F, Peng R, Lu L, Li P-Q, Qiao B, Yang X-Y, Zheng Y-F, Wang H-Y, Gao Y-Q, Chen F-S. Novel mutations of AXIN2 identified in a Chinese Congenital Heart Disease Cohort. J Hum Genet. 2019;[Epub ahead of print] doi:10.1038/s10038-019-0572-x.

tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis

Authors:
Savage AM, Kurusamy S, Chen Y, Jiang Z, Chhabria K, MacDonald RB, Kim HR, Wilson HL, van Eeden FJM, Armesilla AL, Chico TJA, Wilkinson RN
Citation:
Nat Comm. 2019;10:732. doi:10.1038/s41467-019-08590-7
Abstract:
Angiogenesis requires co-ordination of multiple signalling inputs to regulate the behaviour of endothelial cells (ECs) as they...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Savage AM, Kurusamy S, Chen Y, Jiang Z, Chhabria K, MacDonald RB, Kim HR, Wilson HL, van Eeden FJM, Armesilla AL, Chico TJA, Wilkinson RN. tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis. Nat Comm. 2019;10:732. doi:10.1038/s41467-019-08590-7.

The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand

Authors:
Pantazis CB, James MH, Bentzley BS, Aston-Jones G
Citation:
bioRxiv. 2019;[Preprint] doi:10.1101/547836
Abstract:
[no abstract included]
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Rats Sprague-Dawley male
Citation Extract:
Pantazis CB, James MH, Bentzley BS, Aston-Jones G. The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand. bioRxiv. 2019;[Preprint] doi:10.1101/547836.

A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation

Authors:
Hadzhiev Y, Qureshi HK, Wheatley L, Cooper L, Jasiulewicz A, Van Nguyen H, Wragg JW, Poovathumkadavil D, Conic S, Bajan S, Sik A, Hutvàgner G, Tora L, Gambus A, Fossey JS, Müller F
Citation:
Nat Commun. 2019 Feb 11;10(1):691. doi: 10.1038/s41467-019-08487-5
Abstract:
Most metazoan embryos commence development with rapid, transcriptionally silent cell divisions, with genome activation delayed...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hadzhiev Y, Qureshi HK, Wheatley L, Cooper L, Jasiulewicz A, Van Nguyen H, Wragg JW, Poovathumkadavil D, Conic S, Bajan S, Sik A, Hutvàgner G, Tora L, Gambus A, Fossey JS, Müller F. A cell cycle-coordinated Polymerase II transcription compartment encompasses gene expression before global genome activation. Nat Commun. 2019 Feb 11;10(1):691. doi: 10.1038/s41467-019-08487-5.

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