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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 11141 scientific papers returned from the database with the search filters currently being used below.

A self-generated Toddler gradient guides mesodermal cell migration

Authors:
Stock J, Kazmar T, Schlumm F, Hannezo E, Pauli A
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.16.472981
Epub:
Not Epub
Abstract:
The sculpting of germ layers during gastrulation relies on coordinated migration of progenitor cells, yet the cues controlling...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stock J, Kazmar T, Schlumm F, Hannezo E, Pauli A. A self-generated Toddler gradient guides mesodermal cell migration. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.16.472981 .

Differential regulation of SHH signaling and the developmental control of species-specific jaw size through neural crest-mediated Gas1 expression

Authors:
Vavrusová Z, Chu DB, Nguyen A, Fish JL, Schneider RA
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.12.17.473230
Epub:
Not Epub
Abstract:
Developmental control of jaw size is crucial to prevent disease and facilitate evolution. We have shown that species-specific...
Delivery Method:
in ovo injection Vivo-Morpholino
Organism or Cell Type:
Coturnix coturnix japonica (Japanese quail)
Citation Extract:
Vavrusová Z, Chu DB, Nguyen A, Fish JL, Schneider RA. Differential regulation of SHH signaling and the developmental control of species-specific jaw size through neural crest-mediated Gas1 expression. bioRxiv. 2021;[preprint] doi:10.1101/2021.12.17.473230.

l-selenomethionine induces zebrafish embryo cardiovascular defects via down-regulating expression of lrp2b

Authors:
Zhao G, Zhu Y, Hu J, Gao M, Hong Y
Citation:
Chemosphere. 2021 Dec 18:133351. doi: 10.1016/j.chemosphere.2021.133351. Online ahead of print
Epub:
Yes
Abstract:
Selenium plays crucial roles in maintaining the growth and development of vertebrates including humans. However, excessive...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao G, Zhu Y, Hu J, Gao M, Hong Y. l-selenomethionine induces zebrafish embryo cardiovascular defects via down-regulating expression of lrp2b. Chemosphere. 2021 Dec 18:133351. doi: 10.1016/j.chemosphere.2021.133351. Online ahead of print.

Knockdown and Knockout of Tissue Factor Pathway Inhibitor in Zebrafish

Authors:
Raman R, Fallatah W, Al Qaryoute A, Ryon M, Jagadeeswaran P
Citation:
Thromb Haemost. 2021 Dec 16. doi: 10.1055/a-1723-4075. Online ahead of print
Epub:
Yes
Abstract:
Tissue Factor Pathway Inhibitor (TFPI) is an anticoagulant that inhibits factor VIIa and Xa in the blood coagulation pathways....
Delivery Method:
Vivo-Morpholino piggyback hybrid
Organism or Cell Type:
zebrafish
Citation Extract:
Raman R, Fallatah W, Al Qaryoute A, Ryon M, Jagadeeswaran P. Knockdown and Knockout of Tissue Factor Pathway Inhibitor in Zebrafish. Thromb Haemost. 2021 Dec 16. doi: 10.1055/a-1723-4075. Online ahead of print.

A novel role of PRL in regulating epithelial cell density by inducing apoptosis at confluence

Authors:
Lohani S, Funato Y, Akieda Y, Mizutani K, Takai Y, Ishitani T, Miki H
Citation:
J Cell Sci. 2021 Dec 21:jcs.258550. doi: 10.1242/jcs.258550. Online ahead of print
Epub:
Yes
Abstract:
Maintaining proper epithelial cell density is essential for the survival of multicellular organisms. While regulation of cell...
Organism or Cell Type:
zebrafish
Citation Extract:
Lohani S, Funato Y, Akieda Y, Mizutani K, Takai Y, Ishitani T, Miki H. A novel role of PRL in regulating epithelial cell density by inducing apoptosis at confluence. J Cell Sci. 2021 Dec 21:jcs.258550. doi: 10.1242/jcs.258550. Online ahead of print.

Novel pre-clinical model for CDKL5 Deficiency Disorder

Authors:
Serrano RJ, Lee C, Douek AM, Kaslin J, Bryson-Richardson RJ, Sztal TE
Citation:
Dis Model Mech 2021;[Epub] doi:10.1242/dmm.049094
Epub:
Yes
Abstract:
Cyclin-Dependent Kinase-Like-5 (CDKL5) Deficiency Disorder (CDD) is a severe X-linked neurodegenerative disease characterized...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Serrano RJ, Lee C, Douek AM, Kaslin J, Bryson-Richardson RJ, Sztal TE. Novel pre-clinical model for CDKL5 Deficiency Disorder. Dis Model Mech 2021;[Epub] doi:10.1242/dmm.049094.

Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos

Authors:
Orlov EE, Nesterenko AM, Korotkova DD, Parshina EA, Martynova NY, Zaraisky AG
Citation:
Dev Cell. 2021;[Epub] doi:10.1016/j.devcel.2021.11.021
Epub:
Yes
Abstract:
How embryos scale patterning according to size is still not fully understood. Through in silico screening and analysis of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Orlov EE, Nesterenko AM, Korotkova DD, Parshina EA, Martynova NY, Zaraisky AG. Targeted search for scaling genes reveals matrix metalloproteinase 3 as a scaler of the dorsal-ventral pattern in Xenopus laevis embryos. Dev Cell. 2021;[Epub] doi:10.1016/j.devcel.2021.11.021.

Who is the best surrogate for germ stem cell transplantation in fish?

Authors:
Franěk R, Cheng Y, Fučíková M, Kašpar V, Xie X, Shah MA, Linhart O, Šauman I, Pšenička
Citation:
Aquaculture. 2022;549:737759. [Epub] doi:10.1016/j.aquaculture.2021.737759
Epub:
Yes
Abstract:
Surrogate broodstock technology in fishes has potential for aquaculture as well as endangered species conservation and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Franěk R, Cheng Y, Fučíková M, Kašpar V, Xie X, Shah MA, Linhart O, Šauman I, Pšenička. Who is the best surrogate for germ stem cell transplantation in fish?. Aquaculture. 2022;549:737759. [Epub] doi:10.1016/j.aquaculture.2021.737759.

TNNT1 myopathy with novel compound heterozygous mutations

Authors:
Lee S, Eum J, Park S, Ki S, Hwang BJ, Kee Y, Chae JH
Citation:
Neuromuscul Disord. 2021;[Epub ahead of print] doi:10.1016/j.nmd.2021.12.003
Epub:
Not Epub
Abstract:
Nemaline myopathies are clinically and genetically heterogeneous disorders caused by several different genes. One of them is...
Organism or Cell Type:
zebrafish
Citation Extract:
Lee S, Eum J, Park S, Ki S, Hwang BJ, Kee Y, Chae JH. TNNT1 myopathy with novel compound heterozygous mutations. Neuromuscul Disord. 2021;[Epub ahead of print] doi:10.1016/j.nmd.2021.12.003.

Pharmacology and toxicology of eteplirsen and SRP-5051 for DMD exon 51 skipping: an update

Authors:
Sheikh O, Yokota T
Citation:
Arch Toxicol. 2021 Nov 19. doi: 10.1007/s00204-021-03184-z. Online ahead of print
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) afflicts 1 in 5000 newborn males, leading to progressive muscle weakening and the loss of...
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
Sheikh O, Yokota T. Pharmacology and toxicology of eteplirsen and SRP-5051 for DMD exon 51 skipping: an update. Arch Toxicol. 2021 Nov 19. doi: 10.1007/s00204-021-03184-z. Online ahead of print.

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