You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9646 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Mechanical Forces Regulate Cardiomyocyte Myofilament Maturation via the VCL-SSH1-CFL Axis

Authors:
Fukuda R, Gunawan F,Ramadass R, Beisaw A, Konzer A, Mullapudi ST, Gentile A, Maischein H-M, Graumann J, Stainier DYR
Citation:
Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.08.006
Abstract:
Mechanical forces regulate cell behavior and tissue morphogenesis. During cardiac development, mechanical stimuli from the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fukuda R, Gunawan F,Ramadass R, Beisaw A, Konzer A, Mullapudi ST, Gentile A, Maischein H-M, Graumann J, Stainier DYR. Mechanical Forces Regulate Cardiomyocyte Myofilament Maturation via the VCL-SSH1-CFL Axis. Dev Cell. 2019;[Epub ahead of print] doi:10.1016/j.devcel.2019.08.006.

Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome

Authors:
Greenberg RS, Long HK, Swigut T, Wysocka J
Citation:
Cell. 2019;178(6):1421-36. doi:10.1016/j.cell.2019.08.002
Abstract:
The developmental disorder Floating-Harbor syndrome (FHS) is caused by heterozygous truncating mutations in SRCAP, a gene...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Greenberg RS, Long HK, Swigut T, Wysocka J. Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome. Cell. 2019;178(6):1421-36. doi:10.1016/j.cell.2019.08.002.

Inhibition of mmp13a during zebrafish fin regeneration disrupts fin growth, osteoblasts differentiation and Laminin organization

Authors:
Li L, Zhang J, Akimenko MA
Citation:
Dev Dyn. 2019 Sep 5. doi: 10.1002/dvdy.112. [Epub ahead of print]
Abstract:
BACKGROUND: Matrix metalloproteinases 13 (MMP13) is a potent endopeptidase that regulate cell growth, migration, and...
Delivery Method:
injection, electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Li L, Zhang J, Akimenko MA. Inhibition of mmp13a during zebrafish fin regeneration disrupts fin growth, osteoblasts differentiation and Laminin organization. Dev Dyn. 2019 Sep 5. doi: 10.1002/dvdy.112. [Epub ahead of print].

Aspergillus fumigatus establishes infection in zebrafish by germination of phagocytized conidia, while Aspergillus niger relies on extracellular germination

Authors:
Koch BEV, Hajdamowicz NH, Lagendijk E, Ram AFJ, Meijer AH
Citation:
Sci Rep. 2019;9(1):12791. doi:10.1038/s41598-019-49284-w
Abstract:
Among opportunistically pathogenic filamentous fungi of the Aspergillus genus, Aspergillus fumigatus stands out as a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Koch BEV, Hajdamowicz NH, Lagendijk E, Ram AFJ, Meijer AH. Aspergillus fumigatus establishes infection in zebrafish by germination of phagocytized conidia, while Aspergillus niger relies on extracellular germination. Sci Rep. 2019;9(1):12791. doi:10.1038/s41598-019-49284-w.

TRPV4-Mediated Detection of Hyposmotic Stress by Skin Keratinocytes Activates Developmental Immunity

Authors:
Galindo-Villegas J, Montalban-Arques A, Liarte S, de Oliveira S, Pardo-Pastor C, Rubio-Moscardo F, Meseguer J, Valverde MA, Mulero V
Citation:
J Immunol. 2016 Jan 15;196(2):738-49. doi: 10.4049/jimmunol.1501729. Epub 2015 Dec 16. Erratum in: J Immunol. 2016 Apr 15;196(8):3494
Abstract:
As an organism is exposed to pathogens during very early development, specific defense mechanisms must take effect. In this...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Galindo-Villegas J, Montalban-Arques A, Liarte S, de Oliveira S, Pardo-Pastor C, Rubio-Moscardo F, Meseguer J, Valverde MA, Mulero V. TRPV4-Mediated Detection of Hyposmotic Stress by Skin Keratinocytes Activates Developmental Immunity. J Immunol. 2016 Jan 15;196(2):738-49. doi: 10.4049/jimmunol.1501729. Epub 2015 Dec 16. Erratum in: J Immunol. 2016 Apr 15;196(8):3494.

Disruption of splicing-regulatory elements using CRISPR/Cas9 rescues spinal muscular atrophy in human iPSCs and mice

Authors:
Li J-J, Lin X, Cheng Tang, Lu Y-Q, Hu X, Zuo E, Li H, Ying W, Sun Y, Lai L-L, Chen H-Z, Guo X-X, Zhang Q-J, Wu S, Zhou C, Shen X, Wang Q, Lin M-T, Ma L-X, Wang N, Krainer AR, Shi L, Yang H, Chen W-J
Citation:
Nat Sci Rev. 2019;[Epub] doi:10.1093/nsr/nwz131
Abstract:
We here report a genome-editing strategy to correct spinal muscular atrophy (SMA). Rather than directly targeting the...
Organism or Cell Type:
cell culture: SMA-2 iPSC
Citation Extract:
Li J-J, Lin X, Cheng Tang, Lu Y-Q, Hu X, Zuo E, Li H, Ying W, Sun Y, Lai L-L, Chen H-Z, Guo X-X, Zhang Q-J, Wu S, Zhou C, Shen X, Wang Q, Lin M-T, Ma L-X, Wang N, Krainer AR, Shi L, Yang H, Chen W-J. Disruption of splicing-regulatory elements using CRISPR/Cas9 rescues spinal muscular atrophy in human iPSCs and mice. Nat Sci Rev. 2019;[Epub] doi:10.1093/nsr/nwz131.

Myotubularin related protein 7 is essential for the spermatogonial stem cell homeostasis via PI3K/AKT signaling

Authors:
Zhao D, Shen C, Gao T, Li H, Guo Y, Li F, Liu C, Liu Y, Chen X, Zhang X, Wu Y, Yu Y, Lin M, Yuan Y, Chen X, Huang X, Yang S, Yu J, Zhang J, Zheng B
Citation:
Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661174
Abstract:
Myotubularin related protein 7 (MTMR7), a key member of the MTMR family, depicts phosphatase activity and is involved in...
Organism or Cell Type:
mouse testis
Citation Extract:
Zhao D, Shen C, Gao T, Li H, Guo Y, Li F, Liu C, Liu Y, Chen X, Zhang X, Wu Y, Yu Y, Lin M, Yuan Y, Chen X, Huang X, Yang S, Yu J, Zhang J, Zheng B. Myotubularin related protein 7 is essential for the spermatogonial stem cell homeostasis via PI3K/AKT signaling. Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661174.

MicroRNA-mediated control of developmental lymphangiogenesis

Authors:
Jung HM, Hu CT, Fister AM, Davis AE, Castranova D, Pham VN, Price LM, Weinstein BM
Citation:
eLife. 2019;8:e46007. doi: 10.7554/eLife.46007
Abstract:
The post-transcriptional mechanisms contributing to molecular regulation of developmental lymphangiogenesis and lymphatic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jung HM, Hu CT, Fister AM, Davis AE, Castranova D, Pham VN, Price LM, Weinstein BM. MicroRNA-mediated control of developmental lymphangiogenesis. eLife. 2019;8:e46007. doi: 10.7554/eLife.46007.

Loss of CENPF leads to developmental failure in mouse embryos

Authors:
Zhou C-J, Wang X-Y, Han Z, Wang D-H, Ma Y-Z, Liang C-G
Citation:
Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661173
Abstract:
Aneuploidy caused by abnormal chromosome segregation during early embryo development leads to embryonic death or congenital...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte, embryo
Citation Extract:
Zhou C-J, Wang X-Y, Han Z, Wang D-H, Ma Y-Z, Liang C-G. Loss of CENPF leads to developmental failure in mouse embryos. Cell Cycle. 2019;[Epub ahead of print] doi:10.1080/15384101.2019.1661173.

Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice

Authors:
Klein AF, Varela MA, Arandel L, Holland A, Naouar N, Arzumanov A, Seoane D, Revillod L, Bassez G, Ferry A, Jauvin D, Gourdon G, Puymirat J, Gait MJ, Furling D, Wood MJA
Citation:
J Clin Invest. 2019;[Epub ahead of print] doi:10.1172/JCI128205
Abstract:
Antisense oligonucleotides (ASOs) targeting pathologic RNAs have shown promising therapeutic corrections for many genetic...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: patient-derived muscle DM1 mice
Citation Extract:
Klein AF, Varela MA, Arandel L, Holland A, Naouar N, Arzumanov A, Seoane D, Revillod L, Bassez G, Ferry A, Jauvin D, Gourdon G, Puymirat J, Gait MJ, Furling D, Wood MJA. Peptide-conjugated oligonucleotides evoke long-lasting myotonic dystrophy correction in patient-derived cells and mice. J Clin Invest. 2019;[Epub ahead of print] doi:10.1172/JCI128205.

Pages