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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10798 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Somite morphogenesis is required for axial blood vessel formation

Authors:
Paulissen E, Waxman JS, Martin BL
Citation:
bioRxiv. 2021;[preprint] doi:/10.1101/2021.04.07.438831
Epub:
Not Epub
Abstract:
Angioblasts that form the major axial blood vessels of the dorsal aorta and cardinal vein migrate towards the embryonic midline...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Paulissen E, Waxman JS, Martin BL. Somite morphogenesis is required for axial blood vessel formation. bioRxiv. 2021;[preprint] doi:/10.1101/2021.04.07.438831.

Sox8 is sufficient to reprogram ectoderm into ear vesicles and associated neurons

Authors:
Buzzi AL, Chen J, Thiery A, Delile J, Streit A
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.04.20.440617
Epub:
Not Epub
Abstract:
The vertebrate inner ear arises from a pool of progenitors with the potential to give rise to all the sense organs and cranial...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Buzzi AL, Chen J, Thiery A, Delile J, Streit A. Sox8 is sufficient to reprogram ectoderm into ear vesicles and associated neurons. bioRxiv. 2021;[preprint] doi:10.1101/2021.04.20.440617 .

Involvement of Huntingtin in Development and Ciliary Beating Regulation of Larvae of the Sea Urchin, Hemicentrotus pulcherrimus

Authors:
Katow H, Katow T, Yoshida H, Kiyomoto M
Citation:
Int J Mol Sci. 2021;22(10):5116. doi:10.3390/ijms22105116
Epub:
Not Epub
Abstract:
The multiple functions of the wild type Huntington’s disease protein of the sea urchin Hemicentrotus pulcherrimus (Hp-Htt) have...
Delivery Method:
Endo-Porter PEG
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Katow H, Katow T, Yoshida H, Kiyomoto M. Involvement of Huntingtin in Development and Ciliary Beating Regulation of Larvae of the Sea Urchin, Hemicentrotus pulcherrimus. Int J Mol Sci. 2021;22(10):5116. doi:10.3390/ijms22105116.

Knockdown of miR-26a in Zebrafish Leads to Impairment of the Anti-Inflammatory Function of TnP in the Control of Neutrophilia

Authors:
Falcao MAP, Walker COB, Disner GR, Batista-Filho J, Soares ABS, Balan-Lima L, Lima C, Lopes-Ferreira M
Citation:
Fish Shellfish Immunol. 2021;[Epub] doi:10.1016/j.fsi.2021.04.029
Epub:
Yes
Abstract:
Our recent data show the valuable potential of TnP for the development of a new and safe anti-inflammatory drug due to its...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Falcao MAP, Walker COB, Disner GR, Batista-Filho J, Soares ABS, Balan-Lima L, Lima C, Lopes-Ferreira M. Knockdown of miR-26a in Zebrafish Leads to Impairment of the Anti-Inflammatory Function of TnP in the Control of Neutrophilia. Fish Shellfish Immunol. 2021;[Epub] doi:10.1016/j.fsi.2021.04.029.

Identification of Zebrafish Ortholog for Human Coagulation Factor IX and its Age-dependent Expression

Authors:
Iyer N, Al Qaryoute A, Kacham M, Jagadeeswaran P
Citation:
J Thromb Haemost. 2021 May 11. doi: 10.1111/jth.15365. Online ahead of print
Epub:
Yes
Abstract:
Background: Coagulation factor IX (FIX) is a serine protease zymogen involved in the intrinsic blood coagulation pathway, and...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Iyer N, Al Qaryoute A, Kacham M, Jagadeeswaran P. Identification of Zebrafish Ortholog for Human Coagulation Factor IX and its Age-dependent Expression. J Thromb Haemost. 2021 May 11. doi: 10.1111/jth.15365. Online ahead of print.

The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus

Authors:
Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y
Citation:
Proc Nat Acad Sci USA. 2021;118(20):e2100342118. doi:10.1073/pnas.2100342118
Epub:
Not Epub
Abstract:
Fibroblast growth factor (FGF)/extracellular signal-regulated kinase (ERK) signaling plays a crucial role in anterior–posterior...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhang F, Zhu X, Wang P, He Q, Huang H, Zheng T, Li Y, Jia H, Xu L, Zhao H, Colozza G, Tao Q, De Robertis EM, Ding Y. The cytokine FAM3B/PANDER is an FGFR ligand that promotes posterior development in Xenopus. Proc Nat Acad Sci USA. 2021;118(20):e2100342118. doi:10.1073/pnas.2100342118.

High-resolution mapping of the period landscape reveals polymorphism in cell cycle frequency tuning

Authors:
Li Z, Wang S, Sun M, Jin M, Khain D, Yang Q
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.10.442602
Epub:
Not Epub
Abstract:
Many biological oscillators exhibit widely tunable frequency in adapting to environmental changes. Although theoretical studies...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Li Z, Wang S, Sun M, Jin M, Khain D, Yang Q. High-resolution mapping of the period landscape reveals polymorphism in cell cycle frequency tuning. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.10.442602 .

RNA m6A methyltransferase Mettl3 regulates spatial neural patterning in Xenopus

Authors:
Kim H, Jang S
Citation:
Mol Cell Biol. 2021 May 10:MCB.00104-21. doi: 10.1128/MCB.00104-21. Online ahead of print
Epub:
Yes
Abstract:
N6-methyladenosine (m6A) is the most prevalent internal RNA modification, and has a widespread impact on mRNA stability and...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Kim H, Jang S. RNA m6A methyltransferase Mettl3 regulates spatial neural patterning in Xenopus. Mol Cell Biol. 2021 May 10:MCB.00104-21. doi: 10.1128/MCB.00104-21. Online ahead of print.

Cardioluminescence in transgenic zebrafish embryos: a Ca2+ imaging tool to study drug effects and pathological modeling

Authors:
Vicente M, Salgado-Almario J, Collins MM, Martínez-Sielva A, Minoshima M, Kikuchi K, Domingo B, Llopis J
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.05.06.442917
Epub:
Not Epub
Abstract:
The zebrafish embryo has emerged as an excellent model in cardiovascular research. The existing techniques to monitor Ca2+ in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vicente M, Salgado-Almario J, Collins MM, Martínez-Sielva A, Minoshima M, Kikuchi K, Domingo B, Llopis J. Cardioluminescence in transgenic zebrafish embryos: a Ca2+ imaging tool to study drug effects and pathological modeling. bioRxiv. 2021;[preprint] doi:10.1101/2021.05.06.442917.

Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia

Authors:
Wiessner M, Maroofian R, Ni M-Y, Pedroni A, Müller JS, Stucka R, Beetz C, Efthymiou S, Santorelli FM, Alfares AA, Zhu C, Uhrova MA, Alehabib E, Bakhtiari S, Janecke AR, Otero MG, Chen JYH, Peterson JT, Strom TM, De JP, Deconinck T, De Ridder W, De Winter J, Pasquariello R, Ricca I,Alfadhel M, van de Warrenburg BP, Portier R, Bergmann C, Ghasemi FS,Jin SC, Bilguvar K, Hamed S, Abdelhameed M, Haridy NA, Maqbool S, Rahman F, Anwar N, Carmichael J, Pagnamenta A, Wood NW, Tran Mau-Them F, Haack T, Genomics England Research Consortium PREPARE network, Di Rocco M, <authors deleted - database limit> Shamseldin H, Al Tala S, Rezazadeh VJ, Najafi M, Deschner S, Gläser D, Hüttel W, Kruer MC, Kamsteeg E-J, Takiyama Y, Züchner S, Baets J, Synofzik M, Schüle R, Horvath R, Houlden H, Bartesaghi L, Lee H-J, Ampatzis K, Pierson TM, Senderek J
Citation:
Brain. 2021;[Epub] doi:10.1093/brain/awab041
Epub:
Not Epub
Abstract:
Human 4-hydroxyphenylpyruvate dioxygenase-like (HPDL) is a putative iron-containing non-heme oxygenase of unknown specificity...
Organism or Cell Type:
zebrafish
Citation Extract:
Wiessner M, Maroofian R, Ni M-Y, Pedroni A, Müller JS, Stucka R, Beetz C, Efthymiou S, Santorelli FM, Alfares AA, Zhu C, Uhrova MA, Alehabib E, Bakhtiari S, Janecke AR, Otero MG, Chen JYH, Peterson JT, Strom TM, De JP, Deconinck T, De Ridder W, De Winter J, Pasquariello R, Ricca I,Alfadhel M, van de Warrenburg BP, Portier R, Bergmann C, Ghasemi FS,Jin SC, Bilguvar K, Hamed S, Abdelhameed M, Haridy NA, Maqbool S, Rahman F, Anwar N, Carmichael J, Pagnamenta A, Wood NW, Tran Mau-Them F, Haack T, Genomics England Research Consortium PREPARE network, Di Rocco M, <authors deleted - database limit> Shamseldin H, Al Tala S, Rezazadeh VJ, Najafi M, Deschner S, Gläser D, Hüttel W, Kruer MC, Kamsteeg E-J, Takiyama Y, Züchner S, Baets J, Synofzik M, Schüle R, Horvath R, Houlden H, Bartesaghi L, Lee H-J, Ampatzis K, Pierson TM, Senderek J. Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia. Brain. 2021;[Epub] doi:10.1093/brain/awab041.

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