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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10468 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Influence of astrocytic glutamine transporter SN1 deficiency on electrophysiological correlates of glutamatergic transmission

Authors:
Popek M, Bobula B, Sowa J, Hess G, Albrecht J, Zielinska M
Citation:
J Neurochem. 2017; 142(suppl 1):125. doi:10.1111/jnc.14093
Abstract:
The N-system glutamine transporter SN1 preferentially transfers glutamine out of astrocytes (Chaudhry et al., Cell 1999), and...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Popek M, Bobula B, Sowa J, Hess G, Albrecht J, Zielinska M. Influence of astrocytic glutamine transporter SN1 deficiency on electrophysiological correlates of glutamatergic transmission. J Neurochem. 2017; 142(suppl 1):125. doi:10.1111/jnc.14093.

Phosphatidylinositol 4 kinase-β mutations cause non-syndromic sensorineural deafness and inner ear malformation

Authors:
Su X, Feng Y, Rahman SA, Wu S, Li G, Rüschendorf F, Zhao L, Cui H, Liang J, Fang L, Hu H, Froehler S, Yu Y, Patone G, Hummel O, Chen Q, Raile K, Luft FC, Bähring S, Hussain K, Chen W, Zhang J, Gong
Citation:
J Genet Genom. 2020;[Epub] doi:10.1016/j.jgg.2020.07.008
Abstract:
Congenital hearing loss is a common disorder worldwide. Heterogeneous gene variation accounts for approximately 20% - 25% of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Su X, Feng Y, Rahman SA, Wu S, Li G, Rüschendorf F, Zhao L, Cui H, Liang J, Fang L, Hu H, Froehler S, Yu Y, Patone G, Hummel O, Chen Q, Raile K, Luft FC, Bähring S, Hussain K, Chen W, Zhang J, Gong. Phosphatidylinositol 4 kinase-β mutations cause non-syndromic sensorineural deafness and inner ear malformation. J Genet Genom. 2020;[Epub] doi:10.1016/j.jgg.2020.07.008.

Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis

Authors:
Won SY, Kwon S, Jeong HS, Chung KW, Choi BO, Chang JW, Lee JE
Citation:
Stem Cells. 2020 Oct 27. doi: 10.1002/stem.3287. Online ahead of print
Abstract:
In the peripheral nervous system (PNS), proper development of Schwann cells (SCs) contributing to axonal myelination is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Won SY, Kwon S, Jeong HS, Chung KW, Choi BO, Chang JW, Lee JE. Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis. Stem Cells. 2020 Oct 27. doi: 10.1002/stem.3287. Online ahead of print.

Sox2 and Canonical Wnt Signaling Interact to Activate a Developmental Checkpoint Coordinating Morphogenesis with Mesoderm Fate Acquisition

Authors:
Kinney BA, Anber AA, Row RH, Tseng Y-J, Weidmann MD, Knaut H, Martin BL
Citation:
Cell Rep. 2020;33(4):108311. doi:10.1016/j.celrep.2020.108311
Abstract:
Animal embryogenesis requires a precise coordination between morphogenesis and cell fate specification. During mesoderm...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kinney BA, Anber AA, Row RH, Tseng Y-J, Weidmann MD, Knaut H, Martin BL. Sox2 and Canonical Wnt Signaling Interact to Activate a Developmental Checkpoint Coordinating Morphogenesis with Mesoderm Fate Acquisition. Cell Rep. 2020;33(4):108311. doi:10.1016/j.celrep.2020.108311.

GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons

Authors:
Akamine S, Okuzono S, Yamamoto H, Setoyama D, Sagata N, Ohgidani M, Kato TA, Ishitani T, Kato H, Masuda K, Matsushita Y, Ono H, Ishizaki Y, Sanefuji M, Saitsu H, Matsumoto N, Kang D, Kanba S, Nakabeppu Y, Sakai Y, Ohga S
Citation:
FASEB J. 2020 Oct 27;[Epub ahead of print] doi:10.1096/fj.202001113R. Online ahead of print
Abstract:
Developmental and epileptic encephalopathy (DEE) represents a group of neurodevelopmental disorders characterized by infantile‐...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Akamine S, Okuzono S, Yamamoto H, Setoyama D, Sagata N, Ohgidani M, Kato TA, Ishitani T, Kato H, Masuda K, Matsushita Y, Ono H, Ishizaki Y, Sanefuji M, Saitsu H, Matsumoto N, Kang D, Kanba S, Nakabeppu Y, Sakai Y, Ohga S. GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons. FASEB J. 2020 Oct 27;[Epub ahead of print] doi:10.1096/fj.202001113R. Online ahead of print.

Actin-based protrusions lead microtubules during stereotyped axon initiation in spinal neurons in vivo

Authors:
Moore RE, Pop S, Alleyne C, Clarke JDW
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.10.24.353284
Abstract:
In vitro, developing neurons progress through well-defined stages to form an axon and multiple dendrites. In vivo, neurons are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moore RE, Pop S, Alleyne C, Clarke JDW. Actin-based protrusions lead microtubules during stereotyped axon initiation in spinal neurons in vivo. bioRxiv. 2020;[preprint] doi:10.1101/2020.10.24.353284 .

Dual function of perivascular fibroblasts in vascular stabilization in zebrafish

Authors:
Rajan AM, Ma RC, Kocha KM, Zhang DJ, Huang P
Citation:
PLoS Genet. 2020;16(10):e1008800. doi:10.1371/journal.pgen.1008800
Abstract:
Blood vessels are vital to sustain life in all vertebrates. While it is known that mural cells (pericytes and smooth muscle...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rajan AM, Ma RC, Kocha KM, Zhang DJ, Huang P. Dual function of perivascular fibroblasts in vascular stabilization in zebrafish. PLoS Genet. 2020;16(10):e1008800. doi:10.1371/journal.pgen.1008800.

Dopachrome tautomerase variants in patients with oculocutaneous albinism

Authors:
Pennamen P, Tingaud-Sequeira A, Gazova I, Keighren M, McKie L, Marlin S, Gherbi Halem S, Kaplan J, Delevoye C, Lacombe D, Plaisant C, Michaud V, Lasseaux E, Javerzat S, Jackson I, Arveiler B
Citation:
Genet Med. 2020 Oct 26. doi: 10.1038/s41436-020-00997-8. Online ahead of print
Abstract:
Purpose: Albinism is a clinically and genetically heterogeneous condition. Despite analysis of the 20 known genes, ~30%...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pennamen P, Tingaud-Sequeira A, Gazova I, Keighren M, McKie L, Marlin S, Gherbi Halem S, Kaplan J, Delevoye C, Lacombe D, Plaisant C, Michaud V, Lasseaux E, Javerzat S, Jackson I, Arveiler B. Dopachrome tautomerase variants in patients with oculocutaneous albinism. Genet Med. 2020 Oct 26. doi: 10.1038/s41436-020-00997-8. Online ahead of print.

E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow

Authors:
Grimaldi C, Schumacher I, Boquet-Pujadas A, Tarbashevich K, Vos BE, Bandemer J, Schick J, Aalto A, Olivo-Marin JC, Betz T, Raz E
Citation:
Nat Commun. 2020 Oct 26;11(1):5397. doi: 10.1038/s41467-020-19114-z
Abstract:
The migration of many cell types relies on the formation of actomyosin-dependent protrusions called blebs, but the mechanisms...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Grimaldi C, Schumacher I, Boquet-Pujadas A, Tarbashevich K, Vos BE, Bandemer J, Schick J, Aalto A, Olivo-Marin JC, Betz T, Raz E. E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow. Nat Commun. 2020 Oct 26;11(1):5397. doi: 10.1038/s41467-020-19114-z.

The cationic amino acid exporter Slc7a7 is induced and vital in zebrafish tissue macrophages with sustained efferocytic activity

Authors:
Demy DL, Carrère M, Noche R, Tauzin M, Le Bris M, Baek C, Leshchiner I, Goessling W, Herbomel P
Citation:
J Cell Sci. 2020 Oct 22;133(20):jcs249037. doi: 10.1242/jcs.249037
Abstract:
Most tissues harbor a substantial population of resident macrophages. Here, we elucidate a functional link between the Slc7a7...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Demy DL, Carrère M, Noche R, Tauzin M, Le Bris M, Baek C, Leshchiner I, Goessling W, Herbomel P. The cationic amino acid exporter Slc7a7 is induced and vital in zebrafish tissue macrophages with sustained efferocytic activity. J Cell Sci. 2020 Oct 22;133(20):jcs249037. doi: 10.1242/jcs.249037.

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