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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9716 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

MicroRNAs Establish the Right-Handed Dominance of the Heart Laterality Pathway in Vertebrates

Authors:
Rago L, Castroviejo N, Fazilaty H, Garcia-Asencio F, Ocaña OH, Galcerán J, Nieto MA
Citation:
Dev Cell. 2019 Oct 17. pii: S1534-5807(19)30768-3. doi: 10.1016/j.devcel.2019.09.012. [Epub ahead of print]
Abstract:
Despite their external bilateral symmetry, vertebrates have internal left/right (L/R) asymmetries required for optimal organ...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rago L, Castroviejo N, Fazilaty H, Garcia-Asencio F, Ocaña OH, Galcerán J, Nieto MA. MicroRNAs Establish the Right-Handed Dominance of the Heart Laterality Pathway in Vertebrates. Dev Cell. 2019 Oct 17. pii: S1534-5807(19)30768-3. doi: 10.1016/j.devcel.2019.09.012. [Epub ahead of print].

YWHA (14-3-3) protein isoforms and their interactions with CDC25B phosphatase in mouse oogenesis and oocyte maturation

Authors:
Eisa AA, De S, Detwiler A, Gilker E, Ignatious AC, Vijayaraghavan S, Kline D
Citation:
BMC Dev Biol. 2019 Oct 22;19(1):20. doi: 10.1186/s12861-019-0200-1
Abstract:
BACKGROUND: Immature mammalian oocytes are held arrested at prophase I of meiosis by an inhibitory phosphorylation of cyclin-...
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Eisa AA, De S, Detwiler A, Gilker E, Ignatious AC, Vijayaraghavan S, Kline D. YWHA (14-3-3) protein isoforms and their interactions with CDC25B phosphatase in mouse oogenesis and oocyte maturation. BMC Dev Biol. 2019 Oct 22;19(1):20. doi: 10.1186/s12861-019-0200-1.

Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation

Authors:
Schwartz AL, Nath PR, Allgauer M, Lessey-Morillon EC, Sipes JM, Ridnour LA, Morillon Ii YM, Yu Z, Restifo NP, Roberts DD
Citation:
Cancer Immunol Immunother. 2019 Oct 18. doi: 10.1007/s00262-019-02397-7. [Epub ahead of print]
Abstract:
Antibodies targeting the T-cell immune checkpoint cytotoxic T-lymphocyte antigen-4 (CTLA4) enhance the effectiveness of...
Delivery Method:
oligo bathing; injection
Organism or Cell Type:
cell culture: human T cells; C57BL/6 mice with B16F10 melanomas
Citation Extract:
Schwartz AL, Nath PR, Allgauer M, Lessey-Morillon EC, Sipes JM, Ridnour LA, Morillon Ii YM, Yu Z, Restifo NP, Roberts DD. Antisense targeting of CD47 enhances human cytotoxic T-cell activity and increases survival of mice bearing B16 melanoma when combined with anti-CTLA4 and tumor irradiation. Cancer Immunol Immunother. 2019 Oct 18. doi: 10.1007/s00262-019-02397-7. [Epub ahead of print].

Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies

Authors:
Deniz E, Jonas S, Khokha MK, Choma MA
Citation:
Front Physiol. 2019 Sep 20;10:1197. doi:10.3389/fphys.2019.01197. eCollection 2019
Abstract:
Congenital heart disease (CHD) is a significant cause of mortality in infants and adults. Currently human genomic analysis has...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Deniz E, Jonas S, Khokha MK, Choma MA. Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies. Front Physiol. 2019 Sep 20;10:1197. doi:10.3389/fphys.2019.01197. eCollection 2019.

Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish

Authors:
Burczyk MS, Burkhalter MD, Tena TC, Grisanti LA, Kauk M, Matysik S, Donow C, Kustermann M, Rothe M, Cui Y, Raad F, Laue S, Moretti A, Zimmermann W-H, Wess J, Kühl M, Hoffmann C, Tilley DG, Philipp M
Citation:
JCI Insight. 2019;4(20:e121971. doi:10.1172/jci.insight.121971
Abstract:
Deterioration or inborn malformations of the cardiac conduction system (CCS) interfere with proper impulse propagation in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burczyk MS, Burkhalter MD, Tena TC, Grisanti LA, Kauk M, Matysik S, Donow C, Kustermann M, Rothe M, Cui Y, Raad F, Laue S, Moretti A, Zimmermann W-H, Wess J, Kühl M, Hoffmann C, Tilley DG, Philipp M. Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish. JCI Insight. 2019;4(20:e121971. doi:10.1172/jci.insight.121971.

Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia

Authors:
Cheng Chen, Haigen Huang, Ruibin Yan, Shuo Lin and Wei Qin
Citation:
G3 (Bethesda). 2019;9(10):[Epub] doi:10.1534/g3.119.400585
Abstract:
Ribosome is a vital molecular machine for protein translation in the cell. Defects in several ribosomal proteins including...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng Chen, Haigen Huang, Ruibin Yan, Shuo Lin and Wei Qin. Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia. G3 (Bethesda). 2019;9(10):[Epub] doi:10.1534/g3.119.400585.

Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo

Authors:
Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, Masuda T, Shimizu N, Ohkawa Y, Ishitani T
Citation:
Nat Comm. 2019;10(1):4710. doi:10.1038/s41467-019-12609-4
Abstract:
Morphogen signalling forms an activity gradient and instructs cell identities in a signalling strength-dependent manner to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, Masuda T, Shimizu N, Ohkawa Y, Ishitani T. Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo. Nat Comm. 2019;10(1):4710. doi:10.1038/s41467-019-12609-4.

An adhesion code ensures robust pattern formation during tissue morphogenesis

Authors:
Tsai TY-C, Sikora M, Xia P, Colak-Champollion T, Knaut H, Heisenberg C-P, Megason SG
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/803635
Abstract:
An outstanding question in embryo development is how spatial patterns are formed robustly. In the zebrafish spinal cord, neural...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsai TY-C, Sikora M, Xia P, Colak-Champollion T, Knaut H, Heisenberg C-P, Megason SG. An adhesion code ensures robust pattern formation during tissue morphogenesis. bioRxiv. 2019:[preprint] doi:10.1101/803635.

POPDC3 gene variants associate with a new form of limb girdle muscular dystrophy

Authors:
Vissing J, Johnson K, Töpf A, Nafissi S, Díaz-Manera J, French VM, Schindler RF, Sarathchandra P, Løkken N, Rinné S, Freund M, Decher N, Müller T, Duno M, Krag T, Brand T, Straub V
Citation:
Ann Neurol. 2019 Oct 14. doi: 10.1002/ana.25620. [Epub ahead of print]
Abstract:
OBJECTIVE: The Popeye domain containing 3 (POPDC3) gene encodes a membrane protein involved in cAMP signaling. Besides gastric...
Organism or Cell Type:
zebrafish
Citation Extract:
Vissing J, Johnson K, Töpf A, Nafissi S, Díaz-Manera J, French VM, Schindler RF, Sarathchandra P, Løkken N, Rinné S, Freund M, Decher N, Müller T, Duno M, Krag T, Brand T, Straub V. POPDC3 gene variants associate with a new form of limb girdle muscular dystrophy. Ann Neurol. 2019 Oct 14. doi: 10.1002/ana.25620. [Epub ahead of print].

Silencing Breast Cancer Genes using Morpholino Embedded DNA-Tile-AuNPs Nanostructures

Authors:
Tunç CÜ, Öztaş DY, Uzunoglu D, Bayrak ÖF, Culha M
Citation:
Hum Gene Ther. 2019 Oct 14. doi: 10.1089/hum.2019.119. [Epub ahead of print]
Abstract:
There is an ongoing effort to increase the efficiency of gene delivery for the regulation of diseases related genes. In this...
Delivery Method:
nanoparticle
Organism or Cell Type:
cell culture: breast cancer
Citation Extract:
Tunç CÜ, Öztaş DY, Uzunoglu D, Bayrak ÖF, Culha M. Silencing Breast Cancer Genes using Morpholino Embedded DNA-Tile-AuNPs Nanostructures. Hum Gene Ther. 2019 Oct 14. doi: 10.1089/hum.2019.119. [Epub ahead of print].

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