You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9561 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication

Authors:
Halder S, Torrecilla I, Burkhalter MD, Popović M, Fielden J, Vaz B, Oehler J, Pilger D, Lessel D, Wiseman K, Singh AN, Vendrell I, Fischer R, Philipp M, Ramadan K
Citation:
Nat Comm. 2019;10(1):3142. doi:10.1038/s41467-019-11095-y
Abstract:
The SPRTN metalloprotease is essential for DNA-protein crosslink (DPC) repair and DNA replication in vertebrate cells. Cells...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Halder S, Torrecilla I, Burkhalter MD, Popović M, Fielden J, Vaz B, Oehler J, Pilger D, Lessel D, Wiseman K, Singh AN, Vendrell I, Fischer R, Philipp M, Ramadan K. SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication. Nat Comm. 2019;10(1):3142. doi:10.1038/s41467-019-11095-y.

Functions of thioredoxin1 in brain development and in response to environmental chemicals in zebrafish embryos

Authors:
Yang L, Zeng C, Zhang Y, Wang F, Takamiya M, Strähle U
Citation:
Toxicol Lett. 2019:[Epub ahead of print] doi:10.1016/j.toxlet.2019.07.009
Abstract:
Thioredoxin is an evolutionarily conserved antioxidant protein that plays a crucial role for fundamental cellular processes and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang L, Zeng C, Zhang Y, Wang F, Takamiya M, Strähle U. Functions of thioredoxin1 in brain development and in response to environmental chemicals in zebrafish embryos. Toxicol Lett. 2019:[Epub ahead of print] doi:10.1016/j.toxlet.2019.07.009.

The splicing factor Sf3b1 regulates erythroid maturation and proliferation via TGFβ signaling in zebrafish

Authors:
De La Garza A, Cameron RC, Gupta V, Fraint E, Nik S, Bowman TV
Citation:
Blood Adv. 2019 Jul 23;3(14):2093-2104. doi: 10.1182/bloodadvances.2018027714
Abstract:
The spliceosomal component Splicing Factor 3B, subunit 1 (SF3B1) is one of the most prevalently mutated factors in the bone...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
De La Garza A, Cameron RC, Gupta V, Fraint E, Nik S, Bowman TV. The splicing factor Sf3b1 regulates erythroid maturation and proliferation via TGFβ signaling in zebrafish. Blood Adv. 2019 Jul 23;3(14):2093-2104. doi: 10.1182/bloodadvances.2018027714.

Topologically correct central projections of tetrapod inner ear afferents require Fzd3

Authors:
Duncan JS, Fritzsch B, Houston DW, Ketchum EM, Kersigo J, Deans MR, Elliott KL
Citation:
Sci Rep. 2019;9(1):10298. doi:10.1038/s41598-019-46553-6
Abstract:
Inner ear sensory afferent connections establish sensory maps between the inner ear hair cells and the vestibular and auditory...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Duncan JS, Fritzsch B, Houston DW, Ketchum EM, Kersigo J, Deans MR, Elliott KL. Topologically correct central projections of tetrapod inner ear afferents require Fzd3. Sci Rep. 2019;9(1):10298. doi:10.1038/s41598-019-46553-6.

The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand

Authors:
Pantazis CB, James MH, Bentzley BS, Aston-Jones G
Citation:
Addict Biol. 2019 Jul 11:e12795. doi: 10.1111/adb.12795. [Epub ahead of print]
Abstract:
Lateral hypothalamus (LH) orexin neuron signaling has been implicated in the motivation to seek and take drugs of abuse. The...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Rats Sprague-Dawley male
Citation Extract:
Pantazis CB, James MH, Bentzley BS, Aston-Jones G. The number of lateral hypothalamus orexin/hypocretin neurons contributes to individual differences in cocaine demand. Addict Biol. 2019 Jul 11:e12795. doi: 10.1111/adb.12795. [Epub ahead of print].

The human nephrin Y1139RSL motif is essential for podocyte foot process organization and slit diaphragm formation during glomerular development

Authors:
Espiritu EB, Jiang H, Moreau-Marquis S, Sullivan M, Yan K, Beer Stolz D, Sampson MG, Hukriede NA, Swiatecka-Urban A
Citation:
J Biol Chem. 2019 May 31. pii: jbc.RA119.008235. doi: 10.1074/jbc.RA119.008235. [Epub ahead of print]
Abstract:
Nephrin is an immunoglobulin-type cell-adhesion molecule with a key role in the glomerular interpodocyte slit diaphragm....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Espiritu EB, Jiang H, Moreau-Marquis S, Sullivan M, Yan K, Beer Stolz D, Sampson MG, Hukriede NA, Swiatecka-Urban A. The human nephrin Y1139RSL motif is essential for podocyte foot process organization and slit diaphragm formation during glomerular development. J Biol Chem. 2019 May 31. pii: jbc.RA119.008235. doi: 10.1074/jbc.RA119.008235. [Epub ahead of print].

Pectoral Fin Anomalies in tbx5a Knockdown Zebrafish Embryos Related to the Cascade Effect of N-Cadherin and Extracellular Matrix Formation

Authors:
Lu JK, Tsai T-C, Lee H, Hsia K, Lin C-H, Lu J-H
Citation:
J Dev Biol. 2019;7(3):[Epub ahead of print] doi:10.3390/jdb7030015
Abstract:
Functional knockdown of zebrafish tbx5a causes hypoplasia or aplasia of pectoral fins. This study aimed to assess developmental...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu JK, Tsai T-C, Lee H, Hsia K, Lin C-H, Lu J-H. Pectoral Fin Anomalies in tbx5a Knockdown Zebrafish Embryos Related to the Cascade Effect of N-Cadherin and Extracellular Matrix Formation. J Dev Biol. 2019;7(3):[Epub ahead of print] doi:10.3390/jdb7030015.

Zebrafish Wtx is a negative regulator of Wnt signaling but is dispensable for embryonic development and organ homeostasis

Authors:
Große A, Perner B, Naumann U, Englert C
Citation:
Dev Dyn. 2019 Jul 10. doi: 10.1002/dvdy.84. [Epub ahead of print]
Abstract:
BACKGROUND: The X-chromosomally linked gene WTX is a human disease gene and a member of the AMER family. Mutations in WTX are...
Organism or Cell Type:
zebrafish
Citation Extract:
Große A, Perner B, Naumann U, Englert C. Zebrafish Wtx is a negative regulator of Wnt signaling but is dispensable for embryonic development and organ homeostasis. Dev Dyn. 2019 Jul 10. doi: 10.1002/dvdy.84. [Epub ahead of print].

High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration

Authors:
Owens DA, Butler AM, Aguero TH, Newman KM, Van Booven D, King ML
Citation:
Development. 2017 Jan 15;144(2):292-304. doi: 10.1242/dev.139220
Abstract:
During oogenesis, hundreds of maternal RNAs are selectively localized to the animal or vegetal pole, including determinants of...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Owens DA, Butler AM, Aguero TH, Newman KM, Van Booven D, King ML. High-throughput analysis reveals novel maternal germline RNAs crucial for primordial germ cell preservation and proper migration. Development. 2017 Jan 15;144(2):292-304. doi: 10.1242/dev.139220.

Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis

Authors:
Kim S, Chung A-H, Na JE, Lee SJ, Jeong SH, Kim E, Sun W, Rhyu IJ, Park H-C
Citation:
Glia. 2019;[Epub ahead of print] doi:10.1002/glia.23669
Abstract:
Myelin is a specialized membrane that wraps around nerve fibers and is essential for normal axonal conduction in neurons. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kim S, Chung A-H, Na JE, Lee SJ, Jeong SH, Kim E, Sun W, Rhyu IJ, Park H-C. Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis. Glia. 2019;[Epub ahead of print] doi:10.1002/glia.23669.

Pages