You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9320 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

A genetic model of CEDNIK syndrome in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development

Authors:
Mastrodonato V, Beznoussenko G, Mironov A, Ferrari L, Deflorian G, Vaccari T
Citation:
Sci Rep. 2019:1211. doi:10.1038/s41598-018-37780-4
Abstract:
Homozygous mutations in SNAP29, encoding a SNARE protein mainly involved in membrane fusion, cause CEDNIK (Cerebral Dysgenesis...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mastrodonato V, Beznoussenko G, Mironov A, Ferrari L, Deflorian G, Vaccari T. A genetic model of CEDNIK syndrome in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development. Sci Rep. 2019:1211. doi:10.1038/s41598-018-37780-4.

Prickle1 is required for EMT and migration of zebrafish cranial neural crest

Authors:
Ahsan K, Singh N, Rocha M, Huang C, Prince VE
Citation:
Dev Biol. 2019;[Epub ahead of print] doi:10.1016/j.ydbio.2019.01.018
Abstract:
The neural crest -- a key innovation of the vertebrates -- gives rise to diverse cell types including melanocytes, neurons and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ahsan K, Singh N, Rocha M, Huang C, Prince VE. Prickle1 is required for EMT and migration of zebrafish cranial neural crest. Dev Biol. 2019;[Epub ahead of print] doi:10.1016/j.ydbio.2019.01.018.

Biallelic KARS pathogenic variants cause an early-onset progressive leukodystrophy

Authors:
Itoh M, Dai H, Horike SI, Gonzalez J, Kitami Y, Meguro-Horike M, Kuki I, Shimakawa S, Yoshinaga H, Ota Y, Okazaki T, Maegaki Y, Nabatame S, Okazaki S, Kawawaki H, Ueno N, Goto YI, Kato Y
Citation:
Brain. 2019 Feb 3. doi: 10.1093/brain/awz001. [Epub ahead of print]
Abstract:
The leukodystrophies cause severe neurodevelopmental defects from birth and follow an incurable and progressive course that...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Itoh M, Dai H, Horike SI, Gonzalez J, Kitami Y, Meguro-Horike M, Kuki I, Shimakawa S, Yoshinaga H, Ota Y, Okazaki T, Maegaki Y, Nabatame S, Okazaki S, Kawawaki H, Ueno N, Goto YI, Kato Y. Biallelic KARS pathogenic variants cause an early-onset progressive leukodystrophy. Brain. 2019 Feb 3. doi: 10.1093/brain/awz001. [Epub ahead of print].

AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate

Authors:
Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, Traver D, Cooke JP, Li W, Zon LI, Chen K, Bai Y, Fang L
Citation:
Science. 2019 Jan 31. pii: eaav1749. doi: 10.1126/science.aav1749. [Epub ahead of print]
Abstract:
Hypercholesterolemia, the driving force of atherosclerosis, accelerates the expansion and mobilization of hematopoietic stem...
Citation Extract:
Gu Q, Yang X, Lv J, Zhang J, Xia B, Kim JD, Wang R, Xiong F, Meng S, Clements TP, Tandon B, Wagner DS, Diaz MF, Wenzel PL, Miller YI, Traver D, Cooke JP, Li W, Zon LI, Chen K, Bai Y, Fang L. AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science. 2019 Jan 31. pii: eaav1749. doi: 10.1126/science.aav1749. [Epub ahead of print].

A novel nonosteocytic regulatory mechanism of bone modeling

Authors:
Ofer L, Dean MN, Zaslansky P, Kult S, Shwartz Y, Zaretsky J, Griess-Fishheimer S, Monsonego-Ornan E, Zelzer E, Shahar R
Citation:
PLoS Biol. 2019 Feb 1;17(2):e3000140. doi: 10.1371/journal.pbio.3000140. [Epub ahead of print]
Abstract:
Osteocytes, cells forming an elaborate network within the bones of most vertebrate taxa, are thought to be the master...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Ofer L, Dean MN, Zaslansky P, Kult S, Shwartz Y, Zaretsky J, Griess-Fishheimer S, Monsonego-Ornan E, Zelzer E, Shahar R. A novel nonosteocytic regulatory mechanism of bone modeling. PLoS Biol. 2019 Feb 1;17(2):e3000140. doi: 10.1371/journal.pbio.3000140. [Epub ahead of print].

Peli1b governs the brain patterning via ERK signaling pathways in zebrafish embryos

Authors:
Kumar A, Anuppalle M, Maddirevula S, Huh TL, Choe J, Rhee M
Citation:
Gene. 2019 Feb 1. pii: S0378-1119(19)30074-5. doi: 10.1016/j.gene.2018.12.078. [Epub ahead of print]
Abstract:
Pellino proteins are associated with immune and stress responses through their effects on NF-κB signaling and B-cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumar A, Anuppalle M, Maddirevula S, Huh TL, Choe J, Rhee M. Peli1b governs the brain patterning via ERK signaling pathways in zebrafish embryos. Gene. 2019 Feb 1. pii: S0378-1119(19)30074-5. doi: 10.1016/j.gene.2018.12.078. [Epub ahead of print].

Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits

Authors:
Turner KJ, Hoyle J, Valdivia LE, Cerveny KL, Hart W, Mangoli M, Geisler R, Rees M, Houart C, Poole RJ, Wilson SW, Gestri G
Citation:
PLoS One. 2019 Jan 29;14(1):e0211073. doi: 10.1371/journal.pone.0211073. eCollection 2019
Abstract:
Through forward genetic screening for mutations affecting visual system development, we identified prominent coloboma and cell-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Turner KJ, Hoyle J, Valdivia LE, Cerveny KL, Hart W, Mangoli M, Geisler R, Rees M, Houart C, Poole RJ, Wilson SW, Gestri G. Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits. PLoS One. 2019 Jan 29;14(1):e0211073. doi: 10.1371/journal.pone.0211073. eCollection 2019.

ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development

Authors:
Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, Boivin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu C, Jeyasuria P, Bader GD, Hughes TR, Morris QD, Scott MS, Krause H, Angers S, Blencowe BJ, Cummins CL
Citation:
Nucleic Acids Res. 2019 Jan 30. doi: 10.1093/nar/gkz010. [Epub ahead of print]
Abstract:
Stress hormones bind and activate the glucocorticoid receptor (GR) in many tissues including the brain. We identified arginine...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, Boivin V, Robitaille M, Gueroussov S, Irimia M, Ray D, Patel R, Xu C, Jeyasuria P, Bader GD, Hughes TR, Morris QD, Scott MS, Krause H, Angers S, Blencowe BJ, Cummins CL. ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development. Nucleic Acids Res. 2019 Jan 30. doi: 10.1093/nar/gkz010. [Epub ahead of print].

Analysis of cilia dysfunction phenotypes in zebrafish embryos depleted of Origin recognition complex factors

Authors:
Maerz LD, Casar Tena T, Gerhards J, Donow C, Jeggo PA, Philipp M
Citation:
Eur J Hum Genet. 2019 Jan 29. doi: 10.1038/s41431-019-0338-0. [Epub ahead of print]
Abstract:
Meier-Gorlin syndrome (MGS) is a rare, congenital primordial microcephalic dwarfism disorder. MGS is caused by genetic variants...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maerz LD, Casar Tena T, Gerhards J, Donow C, Jeggo PA, Philipp M. Analysis of cilia dysfunction phenotypes in zebrafish embryos depleted of Origin recognition complex factors. Eur J Hum Genet. 2019 Jan 29. doi: 10.1038/s41431-019-0338-0. [Epub ahead of print].

CPSF1 mutations are associated with early-onset high myopia and involved in retinal ganglion cell axon projection

Authors:
Ouyang J, Sun W, Xiao X, Li S, Jia X, Zhou L, Wang P, Zhang Q
Citation:
Hum Mol Genet. 2019 Jan 26. doi: 10.1093/hmg/ddz029. [Epub ahead of print]
Abstract:
High myopia is a severe form of nearsightedness, which can result in blindness due to its associated complications. While both...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ouyang J, Sun W, Xiao X, Li S, Jia X, Zhou L, Wang P, Zhang Q. CPSF1 mutations are associated with early-onset high myopia and involved in retinal ganglion cell axon projection. Hum Mol Genet. 2019 Jan 26. doi: 10.1093/hmg/ddz029. [Epub ahead of print].

Pages