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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9876 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Co-ordinated targeting of galanin receptors on cholangiocytes and hepatic stellate cells ameliorates liver fibrosis in Mdr2-knockout mice

Authors:
Petrescu AD, Grant S, Williams E, Frampton G, Parks N, Blaney H, Davies M, John R, Reinhart EH, McMillin M, DeMorrow S
Citation:
Am J Pathol. 2020 Jan 14. pii: S0002-9440(20)30003-1. doi: 10.1016/j.ajpath.2019.10.023. [Epub ahead of print]
Abstract:
Galanin (Gal) is a peptide with a role in neuroendocrine regulation of the liver. In this study we assessed the role of Gal and...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Petrescu AD, Grant S, Williams E, Frampton G, Parks N, Blaney H, Davies M, John R, Reinhart EH, McMillin M, DeMorrow S. Co-ordinated targeting of galanin receptors on cholangiocytes and hepatic stellate cells ameliorates liver fibrosis in Mdr2-knockout mice. Am J Pathol. 2020 Jan 14. pii: S0002-9440(20)30003-1. doi: 10.1016/j.ajpath.2019.10.023. [Epub ahead of print].

Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model

Authors:
Da'as SI, Yalcin HC, Nasrallah GK, Mohamed IA, Nomikos M, Yacoub MH, Fakhro KA
Citation:
J Cell Physiol. 2020 Jan 13. doi: 10.1002/jcp.29441. [Epub ahead of print]
Abstract:
Myosin‐binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Da'as SI, Yalcin HC, Nasrallah GK, Mohamed IA, Nomikos M, Yacoub MH, Fakhro KA. Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model. J Cell Physiol. 2020 Jan 13. doi: 10.1002/jcp.29441. [Epub ahead of print].

Leucine-rich repeat containing 8A contributes to the expansion of brain ventricles in zebrafish embryos

Authors:
Tseng YT, Ko CL, Chang CT, Lee YH, Huang Fu WC, Liu IH
Citation:
Biol Open. 2020 Jan 15. pii: bio.048264. doi: 10.1242/bio.048264. [Epub ahead of print]
Abstract:
The sodium osmotic gradient is necessary for the initiation of brain ventricle inflation, but a previous study predicted that...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tseng YT, Ko CL, Chang CT, Lee YH, Huang Fu WC, Liu IH. Leucine-rich repeat containing 8A contributes to the expansion of brain ventricles in zebrafish embryos. Biol Open. 2020 Jan 15. pii: bio.048264. doi: 10.1242/bio.048264. [Epub ahead of print].

Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome

Authors:
Chiang CY, Ching YH, Chang TY, Hu LS, Yong YS, Keak PY, Mustika I, Lin MD, Liao BY
Citation:
Comput Struct Biotechnol J. 2019 Dec 27;18:73-82. doi: 10.1016/j.csbj.2019.12.009. eCollection 2020
Abstract:
In the last few decades, reverse genetic and high throughput approaches have been frequently applied to the mouse (Mus musculus...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chiang CY, Ching YH, Chang TY, Hu LS, Yong YS, Keak PY, Mustika I, Lin MD, Liao BY. Novel eye genes systematically discovered through an integrated analysis of mouse transcriptomes and phenome. Comput Struct Biotechnol J. 2019 Dec 27;18:73-82. doi: 10.1016/j.csbj.2019.12.009. eCollection 2020.

Germ plasm localisation dynamics mark distinct phases of transcriptional and post-transcriptional regulation control in primordial germ cells

Authors:
D'Orazio FM, Balwierz P, Guo Y, Rodriguez B, Jasiulewicz A, Vaquerizas JM, Cairns B, Lenhard B, Mueller F
Citation:
https://www.biorxiv.org/content/10.1101/2020.01.12.903336v1
Abstract:
In many animal models, primordial germ cell (PGC) development depends on maternally-deposited germ plasm to avoid somatic cell...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
D'Orazio FM, Balwierz P, Guo Y, Rodriguez B, Jasiulewicz A, Vaquerizas JM, Cairns B, Lenhard B, Mueller F. Germ plasm localisation dynamics mark distinct phases of transcriptional and post-transcriptional regulation control in primordial germ cells. https://www.biorxiv.org/content/10.1101/2020.01.12.903336v1.

Functional characterization of human myosin‐binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon‐specific cardiac phenotypes in zebrafish model

Authors:
Da'as SI, Yalcin HC, Nasrallah GK, Mohamed IA, Nomikos M, Yacoub M, Fakhro KA
Citation:
J Cellular Phys. 2020;[Epub ahead of print] doi:10.1002/jcp.29441
Abstract:
Myosin‐binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Da'as SI, Yalcin HC, Nasrallah GK, Mohamed IA, Nomikos M, Yacoub M, Fakhro KA. Functional characterization of human myosin‐binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon‐specific cardiac phenotypes in zebrafish model. J Cellular Phys. 2020;[Epub ahead of print] doi:10.1002/jcp.29441.

The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels

Authors:
Greenwood IA, Stott JB
Citation:
Front Physiol. 2020;10:1573. doi:10.3389/fphys.2019.01573
Abstract:
Within the vasculature Kv7 channels are key regulators of basal tone and contribute to a variety of receptor mediated...
Delivery Method:
Lipofectamine 2000
Organism or Cell Type:
cell culture: rat primary renal arteries
Citation Extract:
Greenwood IA, Stott JB. The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels. Front Physiol. 2020;10:1573. doi:10.3389/fphys.2019.01573.

Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes

Authors:
Cunningham CM, Bellipanni G, Habas R, Balciunas D
Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.01.12.903211
Abstract:
Two complimentary approaches are widely used to study gene function in zebrafish: induction of genetic mutations, usually using...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cunningham CM, Bellipanni G, Habas R, Balciunas D. Deletion of MOrpholino Binding Sites (DeMOBS) to Assess Specificity of Morphant Phenotypes. bioRxiv. 2020;[preprint] doi:10.1101/2020.01.12.903211 .

Slc7a14 Is Indispensable in Zebrafish Retinas

Authors:
Zhuang YY, Xiang L, Wen XR, Shen RJ, Zhao N, Zheng SS, Han RY, Qu J, Lu F, Jin ZB
Citation:
Front Cell Dev Biol. 2019 Dec 12;7:333. doi: 10.3389/fcell.2019.00333. eCollection 2019
Abstract:
Previous study has identified SLC7A14 as a new causative gene of retinitis pigmentosa (RP). However, the role of SLC7A14 has...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhuang YY, Xiang L, Wen XR, Shen RJ, Zhao N, Zheng SS, Han RY, Qu J, Lu F, Jin ZB. Slc7a14 Is Indispensable in Zebrafish Retinas. Front Cell Dev Biol. 2019 Dec 12;7:333. doi: 10.3389/fcell.2019.00333. eCollection 2019.

Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish

Authors:
El-Maï M, Marzullo M, de Castro IP, Ferreira MG
Citation:
bioRxiv. 2020;[preprint] doi:/10.1101/2020.01.10.901603
Abstract:
Progressive telomere shortening during lifespan is associated with increased genome instability, block to cell proliferation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
El-Maï M, Marzullo M, de Castro IP, Ferreira MG. Akt/Foxo pathway activation switches apoptosis to senescence in short telomere zebrafish. bioRxiv. 2020;[preprint] doi:/10.1101/2020.01.10.901603.

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