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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 11761 scientific papers returned from the database with the search filters currently being used below.
There are 11761 scientific papers returned from the database with the search filters currently being used below.
CCN6 influences transcription and controls mitochondrial mass and muscle organization
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Citation:
FASEB J. 2023 Mar;37(3):e22815. doi: 10.1096/fj.202201533R Epub:
Yes Abstract:
Mutations in Cellular Communication Network Factor 6 (CCN6) are linked to the debilitating musculoskeletal disease Progressive... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ganguly A, Padhan DK, Sengupta A, Chakraborty P, Sen M. CCN6 influences transcription and controls mitochondrial mass and muscle organization. FASEB J. 2023 Mar;37(3):e22815. doi: 10.1096/fj.202201533R. |
EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy
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Citation:
Arterioscler Thromb Vasc Biol. 2023 Feb 16. doi: 10.1161/ATVBAHA.122.318110. Online ahead of print Epub:
Yes Abstract:
Background: Hemodynamic wall shear stress (WSS) exerted on the endothelium by flowing blood determines the spatial distribution... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Canham L, Sendac S, Diagbouga MR, Wolodimeroff E, Pirri D, Tardajos Ayllon B, Feng S, Souilhol C, Chico TJA, Evans PC, Serbanovic-Canic J. EVA1A (Eva-1 Homolog A) Promotes Endothelial Apoptosis and Inflammatory Activation Under Disturbed Flow Via Regulation of Autophagy. Arterioscler Thromb Vasc Biol. 2023 Feb 16. doi: 10.1161/ATVBAHA.122.318110. Online ahead of print. |
Therapeutic Phosphorodiamidate Morpholino Oligonucleotides, an RNA mimic: Physical Properties, Solution Structures, and Folding Thermodynamics
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Citation:
Mol Ther Nucleic Acids. 2023 Feb 14;31:631-647. doi:10.1016/j.omtn.2023.02.007 Epub:
Yes Abstract:
Elucidating the structure-function relationships for therapeutic RNA mimicking phosphorodiamidate morpholino oligonucleotides (... Citation Extract: Maksudov F, Kliuchnikov E, Pierson D, Ujwal ML, Marx KA, Chanda A, Barsegov V. Therapeutic Phosphorodiamidate Morpholino Oligonucleotides, an RNA mimic: Physical Properties, Solution Structures, and Folding Thermodynamics. Mol Ther Nucleic Acids. 2023 Feb 14;31:631-647. doi:10.1016/j.omtn.2023.02.007. |
The genetic basis and potential molecular mechanism of yellow-albino northern snakehead (Channa argus)
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Citation:
Open Biol. 2023 Feb;13(2):220235. doi: 10.1098/rsob.220235. Epub 2023 Feb 15 Epub:
Not Epub Abstract:
Body colour is an important economic trait for commercial fishes. Recently, a new colour morph displaying market-favoured... Delivery Method:
microinjection Organism or Cell Type:
Channa argus (northern snakehead fish) Citation Extract: Sun D, Qi X, Wen H, Li C, Li J, Chen J, Tao Z, Zhu M, Zhang X, Li Y. The genetic basis and potential molecular mechanism of yellow-albino northern snakehead (Channa argus). Open Biol. 2023 Feb;13(2):220235. doi: 10.1098/rsob.220235. Epub 2023 Feb 15. |
Milk fat globule epidermal growth factor 8a regulates neurogenesis in telencephalon and affects larval behavior in zebrafish
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Citation:
Stem Cells Dev. 2023 Feb 14. doi: 10.1089/scd.2022.0247. Online ahead of print Epub:
Yes Abstract:
Mfge8, a secreted glycoprotein, is a key molecule that mediates the phagocytosis of apoptotic cells. Previous research reported... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Luo Y, Lu D, Zhou J, Wu J, Wang W, Qian L. Milk fat globule epidermal growth factor 8a regulates neurogenesis in telencephalon and affects larval behavior in zebrafish. Stem Cells Dev. 2023 Feb 14. doi: 10.1089/scd.2022.0247. Online ahead of print. |
Clcf1/Crlf1a-mediated signaling is neuroprotective and required for Müller glia proliferation in the light-damaged zebrafish retina
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Citation:
Front Cell Dev Biol. 2023;11:1142586. doi:10.3389/fcell.2023.1142586 Epub:
Not Epub Abstract:
Zebrafish possess the innate ability to fully regenerate any neurons lost following a retinal injury. This response is mediated... Delivery Method:
intravitreal (intraocular) injection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Boyd P, Campbell LJ, Hyde DR. Clcf1/Crlf1a-mediated signaling is neuroprotective and required for Müller glia proliferation in the light-damaged zebrafish retina. Front Cell Dev Biol. 2023;11:1142586. doi:10.3389/fcell.2023.1142586. |
Human genetic defects in SRP19 and SRPRA cause severe congenital neutropenia with distinctive proteome changes
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Citation:
Blood. 2023;141(6):645-58. doi:10.1182/blood.2022016783 Epub:
Not Epub Abstract:
The mechanisms of coordinated changes in proteome composition and their relevance for the differentiation of neutrophil... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Linder MI, Mizoguchi Y, Hesse S, Csaba G, Tatematsu M, Łyszkiewicz M, Ziȩtara N, Jeske T, Hastreiter M, Rohlfs M, Liu Y, Grabowski P, Ahomaa K, Maier-Begandt D, Schwestka M, Pazhakh V, Isiaku AI, Miranda BB, Blombery P, Saito MK, Rusha E, Alizadeh Z, Pourpak Z, Kobayashi M, Rezaei N, Unal E, Hauck F, Drukker M, Walzog B, Rappsilber J, Zimmer R, Lieschke GJ, Klein C. Human genetic defects in SRP19 and SRPRA cause severe congenital neutropenia with distinctive proteome changes. Blood. 2023;141(6):645-58. doi:10.1182/blood.2022016783. |
Converging Role for REEP1/SPG31 in Oxidative Stress
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Citation:
Int J Mol Sci. 2023;24(4):3527. doi:10.3390/ijms24043527 Epub:
Not Epub Abstract:
Mutations in the receptor expression-enhancing protein 1 gene (REEP1) are associated with hereditary spastic paraplegia type 31... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Naef V, Meschini MC, Tessa A, Morani F, Corsinovi D, Ogi A, Marchese M, Ori M, Santorelli FM, Doccini S. Converging Role for REEP1/SPG31 in Oxidative Stress. Int J Mol Sci. 2023;24(4):3527. doi:10.3390/ijms24043527. |
Systemic administration of the antisense oligonucleotide NS-089/NCNP-02 for skipping of exon 44 in patients with Duchenne muscular dystrophy: study protocol for a phase I/II clinical trial
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Citation:
medRxiv. 2023;[preprint] doi:10.1101/2023.02.06.23285500 Epub:
Not Epub Abstract:
Aim: The purpose of this study is to evaluate the safety and pharmacokinetics of the novel morpholino oligomer NS-089/NCNP-02... Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Ishizuka T, Komaki H, Asahina Y, Nakamura H, Motohashi N, Takeshita E, Motohashi Y, Ishiyama A, Yonee C, Maruyama S, Hida E, Aoki Y. Systemic administration of the antisense oligonucleotide NS-089/NCNP-02 for skipping of exon 44 in patients with Duchenne muscular dystrophy: study protocol for a phase I/II clinical trial. medRxiv. 2023;[preprint] doi:10.1101/2023.02.06.23285500 . |
Specific Activation of Yamanaka Factors via HSF1 Signaling in the Early Stage of Zebrafish Optic Nerve Regeneration
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Citation:
Int J Mol Sci. 2023;24(4):3253. doi:10.3390/ijms24043253 Epub:
Not Epub Abstract:
In contrast to the case in mammals, the fish optic nerve can spontaneously regenerate and visual function can be fully restored... Delivery Method:
Vivo-Morpholino intraocular injection Organism or Cell Type:
zebrafish Citation Extract: Sugitani K, Mokuya T, Homma S, Maeda M, Konno A, Ogai K. Specific Activation of Yamanaka Factors via HSF1 Signaling in the Early Stage of Zebrafish Optic Nerve Regeneration. Int J Mol Sci. 2023;24(4):3253. doi:10.3390/ijms24043253. |