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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9743 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies

Authors:
Deniz E, Jonas S, Khokha MK, Choma MA
Citation:
Front Physiol. 2019 Sep 20;10:1197. doi:10.3389/fphys.2019.01197. eCollection 2019
Abstract:
Congenital heart disease (CHD) is a significant cause of mortality in infants and adults. Currently human genomic analysis has...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Deniz E, Jonas S, Khokha MK, Choma MA. Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies. Front Physiol. 2019 Sep 20;10:1197. doi:10.3389/fphys.2019.01197. eCollection 2019.

Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish

Authors:
Burczyk MS, Burkhalter MD, Tena TC, Grisanti LA, Kauk M, Matysik S, Donow C, Kustermann M, Rothe M, Cui Y, Raad F, Laue S, Moretti A, Zimmermann W-H, Wess J, Kühl M, Hoffmann C, Tilley DG, Philipp M
Citation:
JCI Insight. 2019;4(20:e121971. doi:10.1172/jci.insight.121971
Abstract:
Deterioration or inborn malformations of the cardiac conduction system (CCS) interfere with proper impulse propagation in the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burczyk MS, Burkhalter MD, Tena TC, Grisanti LA, Kauk M, Matysik S, Donow C, Kustermann M, Rothe M, Cui Y, Raad F, Laue S, Moretti A, Zimmermann W-H, Wess J, Kühl M, Hoffmann C, Tilley DG, Philipp M. Muscarinic receptors promote pacemaker fate at the expense of secondary conduction system tissue in zebrafish. JCI Insight. 2019;4(20:e121971. doi:10.1172/jci.insight.121971.

Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia

Authors:
Cheng Chen, Haigen Huang, Ruibin Yan, Shuo Lin and Wei Qin
Citation:
G3 (Bethesda). 2019;9(10):[Epub] doi:10.1534/g3.119.400585
Abstract:
Ribosome is a vital molecular machine for protein translation in the cell. Defects in several ribosomal proteins including...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cheng Chen, Haigen Huang, Ruibin Yan, Shuo Lin and Wei Qin. Loss of rps9 in Zebrafish Leads to p53-Dependent Anemia. G3 (Bethesda). 2019;9(10):[Epub] doi:10.1534/g3.119.400585.

Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo

Authors:
Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, Masuda T, Shimizu N, Ohkawa Y, Ishitani T
Citation:
Nat Comm. 2019;10(1):4710. doi:10.1038/s41467-019-12609-4
Abstract:
Morphogen signalling forms an activity gradient and instructs cell identities in a signalling strength-dependent manner to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, Masuda T, Shimizu N, Ohkawa Y, Ishitani T. Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo. Nat Comm. 2019;10(1):4710. doi:10.1038/s41467-019-12609-4.

An adhesion code ensures robust pattern formation during tissue morphogenesis

Authors:
Tsai TY-C, Sikora M, Xia P, Colak-Champollion T, Knaut H, Heisenberg C-P, Megason SG
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/803635
Abstract:
An outstanding question in embryo development is how spatial patterns are formed robustly. In the zebrafish spinal cord, neural...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsai TY-C, Sikora M, Xia P, Colak-Champollion T, Knaut H, Heisenberg C-P, Megason SG. An adhesion code ensures robust pattern formation during tissue morphogenesis. bioRxiv. 2019:[preprint] doi:10.1101/803635.

POPDC3 gene variants associate with a new form of limb girdle muscular dystrophy

Authors:
Vissing J, Johnson K, Töpf A, Nafissi S, Díaz-Manera J, French VM, Schindler RF, Sarathchandra P, Løkken N, Rinné S, Freund M, Decher N, Müller T, Duno M, Krag T, Brand T, Straub V
Citation:
Ann Neurol. 2019 Oct 14. doi: 10.1002/ana.25620. [Epub ahead of print]
Abstract:
OBJECTIVE: The Popeye domain containing 3 (POPDC3) gene encodes a membrane protein involved in cAMP signaling. Besides gastric...
Organism or Cell Type:
zebrafish
Citation Extract:
Vissing J, Johnson K, Töpf A, Nafissi S, Díaz-Manera J, French VM, Schindler RF, Sarathchandra P, Løkken N, Rinné S, Freund M, Decher N, Müller T, Duno M, Krag T, Brand T, Straub V. POPDC3 gene variants associate with a new form of limb girdle muscular dystrophy. Ann Neurol. 2019 Oct 14. doi: 10.1002/ana.25620. [Epub ahead of print].

Silencing Breast Cancer Genes using Morpholino Embedded DNA-Tile-AuNPs Nanostructures

Authors:
Tunç CÜ, Öztaş DY, Uzunoglu D, Bayrak ÖF, Culha M
Citation:
Hum Gene Ther. 2019 Oct 14. doi: 10.1089/hum.2019.119. [Epub ahead of print]
Abstract:
There is an ongoing effort to increase the efficiency of gene delivery for the regulation of diseases related genes. In this...
Delivery Method:
nanoparticle
Organism or Cell Type:
cell culture: breast cancer
Citation Extract:
Tunç CÜ, Öztaş DY, Uzunoglu D, Bayrak ÖF, Culha M. Silencing Breast Cancer Genes using Morpholino Embedded DNA-Tile-AuNPs Nanostructures. Hum Gene Ther. 2019 Oct 14. doi: 10.1089/hum.2019.119. [Epub ahead of print].

Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1-/- zebrafish

Authors:
Soman S, Keatinge M, Moein M, Da Costa M, Mortiboys H, Skupin A, Sugunan S, Bazala M, Kuznicki J, Bandmann O
Citation:
Eur J Neurosci. 2017 Feb;45(4):528-535. doi: 10.1111/ejn.13473. Epub 2016 Dec 28
Abstract:
Mutations in PTEN-induced putative kinase 1 (PINK1) are a cause of early onset Parkinson's disease (PD). Loss of PINK1...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Soman S, Keatinge M, Moein M, Da Costa M, Mortiboys H, Skupin A, Sugunan S, Bazala M, Kuznicki J, Bandmann O. Inhibition of the mitochondrial calcium uniporter rescues dopaminergic neurons in pink1-/- zebrafish. Eur J Neurosci. 2017 Feb;45(4):528-535. doi: 10.1111/ejn.13473. Epub 2016 Dec 28.

CTENO64 Is Required for Coordinated Paddling of Ciliary Comb Plate in Ctenophores

Authors:
Jokura K, Shibata D, Yamaguchi K, Shiba K, Makino Y, Shigenobu S, Inaba K
Citation:
Curr Biol. 2019;29:[Epub in press] doi:10.1016/j.cub.2019.08.059
Abstract:
Ctenophores, or comb jellies, are one of the earliestbranching basal metazoan groups, whose phyloge-netic position continues to...
Delivery Method:
microinjection
Organism or Cell Type:
Bolinopsis mikado (Ctenophore, comb jelly)
Citation Extract:
Jokura K, Shibata D, Yamaguchi K, Shiba K, Makino Y, Shigenobu S, Inaba K. CTENO64 Is Required for Coordinated Paddling of Ciliary Comb Plate in Ctenophores. Curr Biol. 2019;29:[Epub in press] doi:10.1016/j.cub.2019.08.059.

Systematic Approach to Developing Splice Modulating Antisense Oligonucleotides

Authors:
Aung-Htut MT, McIntosh CS, Ham KA, Pitout IL, Flynn LL, Greer K, Fletcher S, Wilton SD
Citation:
Int J Mol Sci. 2019;20(20):5030. doi:10.3390/ijms20205030
Abstract:
The process of pre-mRNA splicing is a common and fundamental step in the expression of most human genes. Alternative splicing,...
Citation Extract:
Aung-Htut MT, McIntosh CS, Ham KA, Pitout IL, Flynn LL, Greer K, Fletcher S, Wilton SD. Systematic Approach to Developing Splice Modulating Antisense Oligonucleotides. Int J Mol Sci. 2019;20(20):5030. doi:10.3390/ijms20205030.

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