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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 9743 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog/Gli Is Required for Tracheoesophageal Separation

Authors:
Nasr T, Mancini P, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, SL, Cha S-W, Wells JM, Kofron MJ, Zorn AM
Citation:
bioRxiv. 2019[preprint] doi:10.1101/777664
Abstract:
The trachea and esophagus arise from the separation of a common foregut tube during early fetal development. Mutations in key...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Nasr T, Mancini P, Rankin SA, Edwards NA, Agricola ZN, Kenny AP, Kinney JL, Daniels K, Vardanyan J, Han L, SL, Cha S-W, Wells JM, Kofron MJ, Zorn AM. Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog/Gli Is Required for Tracheoesophageal Separation. bioRxiv. 2019[preprint] doi:10.1101/777664 .

ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia

Authors:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P
Citation:
Cell Rep. 2019;[Epub ahead of print] doi:10.1016/j.celrep.2019.08.063
Abstract:
Mucociliary epithelia provide a first line of defense against pathogens. Impaired regeneration and remodeling of mucociliary...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Haas M, Vázquez JLG, Sun DI, Tran HT, Brislinger M, Tasca A, Shomroni O, Vleminckx K, Walentek P. ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia. Cell Rep. 2019;[Epub ahead of print] doi:10.1016/j.celrep.2019.08.063.

lncrps25 play an essential role in motor neuron development through controlling the expression of olig2 in zebrafish

Authors:
Gao T, Li J, Li N, Gao Y, Yu L, Zhuang S, Zhao Y, Dong X
Citation:
J Cell Phys. 2019;[Epub ahead of print] doi:10.1002/jcp.29237
Abstract:
lncrps25 is an intergenic long noncoding RNA (lncRNA), which is location close to rps25 (ribosomal protein S25) gene, is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao T, Li J, Li N, Gao Y, Yu L, Zhuang S, Zhao Y, Dong X. lncrps25 play an essential role in motor neuron development through controlling the expression of olig2 in zebrafish. J Cell Phys. 2019;[Epub ahead of print] doi:10.1002/jcp.29237.

Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b

Authors:
Ye D, Wang X, Wei C, He M, Wang H, Wang Y, Zhu Z, Sun Y
Citation:
PLoS Genet. 2019 Sep 23;15(9):e1008306. doi: 10.1371/journal.pgen.1008306. [Epub ahead of print]
Abstract:
During vertebrate early embryogenesis, the ventral development is directed by the ventral-to-dorsal activity gradient of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ye D, Wang X, Wei C, He M, Wang H, Wang Y, Zhu Z, Sun Y. Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b. PLoS Genet. 2019 Sep 23;15(9):e1008306. doi: 10.1371/journal.pgen.1008306. [Epub ahead of print].

Cadherin switch marks germ layer formation in the diploblastic sea anemone Nematostella vectensis

Authors:
Pukhlyakova EA, Kirillova AO, Kraus YA, Zimmermann B, Technau U
Citation:
Development. 2019 Sep 20. pii: dev.174623. doi: 10.1242/dev.174623. [Epub ahead of print]
Abstract:
Morphogenesis is a shape-building process during development of multicellular organisms. During this process the establishment...
Delivery Method:
microinjection
Organism or Cell Type:
Nematostella vectensis (sea anemone)
Citation Extract:
Pukhlyakova EA, Kirillova AO, Kraus YA, Zimmermann B, Technau U. Cadherin switch marks germ layer formation in the diploblastic sea anemone Nematostella vectensis. Development. 2019 Sep 20. pii: dev.174623. doi: 10.1242/dev.174623. [Epub ahead of print].

Hexose potentiates peptide-conjugated morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner

Authors:
Han G, Gu B, Lin C, Ning H, Song J, Gao X, Moulton HM, Yin HF
Citation:
Mol Ther Nucl Acids. 2019 Sep 23;18:341-350. doi: 10.1016/j.omtn.2019.09.012. [Epub ahead of print]
Abstract:
Insufficient delivery of oligonucleotides to muscle and heart remains a barrier for clinical implementation of antisense...
Delivery Method:
peptide-linked
Organism or Cell Type:
mice mdx
Citation Extract:
Han G, Gu B, Lin C, Ning H, Song J, Gao X, Moulton HM, Yin HF. Hexose potentiates peptide-conjugated morpholino oligomer efficacy in cardiac muscles of dystrophic mice in an age-dependent manner. Mol Ther Nucl Acids. 2019 Sep 23;18:341-350. doi: 10.1016/j.omtn.2019.09.012. [Epub ahead of print].

The gastrointestinal development ‘parts list’: transcript profiling of embryonic gut development in wildtype and Ret-deficient mice

Authors:
Chatterjee S, Nandakumar P, Auer DR, Gabriel SB, Chakravarti A
Citation:
bioRxiv. 2019;[preprint] doi: 10.1101/730010
Abstract:
The development of the gut from endodermal tissue to an organ with multiple distinct structures and functions occurs over a...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chatterjee S, Nandakumar P, Auer DR, Gabriel SB, Chakravarti A. The gastrointestinal development ‘parts list’: transcript profiling of embryonic gut development in wildtype and Ret-deficient mice. bioRxiv. 2019;[preprint] doi: 10.1101/730010 .

Neuroblast sensory quiescence depends of vascular cytoneme contacts and sensory neuronal differentiation requires initiation of blood flow

Authors:
Taberner L, Bañón A, Alsina B
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/667519
Abstract:
In many organs, stem cell function depends on the communication with their niche partners. Cranial sensory neurons develop in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Taberner L, Bañón A, Alsina B. Neuroblast sensory quiescence depends of vascular cytoneme contacts and sensory neuronal differentiation requires initiation of blood flow. bioRxiv. 2019;[preprint] doi:10.1101/667519 .

Hingepoints and neural folds reveal conserved features of primary neurulation in the zebrafish forebrain

Authors:
Werner JM, Negesse MY, Brooks DL, Caldwell AR, Johnson JM, Brewster R
Citation:
bioRxiv. 2019;[preprint] doi:/10.1101/738161
Abstract:
Primary neurulation is the process by which the neural tube, the central nervous system precursor, is formed from the neural...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Werner JM, Negesse MY, Brooks DL, Caldwell AR, Johnson JM, Brewster R. Hingepoints and neural folds reveal conserved features of primary neurulation in the zebrafish forebrain. bioRxiv. 2019;[preprint] doi:/10.1101/738161 .

Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles

Authors:
Kuhn J, Klein PM, Al Danaf N, Nordin JZ, Reinhard S, Loy DM, Höhn M, El Andaloussi S, Lamb DC, Wagner E, Aoki Y, Lehto T, Lächelt U
Citation:
Adv Funct Mater. 2019;[Epub] doi:10.1002/adfm.201906432
Abstract:
Phosphorodiamidate morpholino oligomers (PMOs) are oligonucleotide analogs that can be used for therapeutic modulation of pre‐...
Delivery Method:
nanoparticle
Organism or Cell Type:
cell culture: HeLa pLuc/705, mdx52 skeletal myotubes
Citation Extract:
Kuhn J, Klein PM, Al Danaf N, Nordin JZ, Reinhard S, Loy DM, Höhn M, El Andaloussi S, Lamb DC, Wagner E, Aoki Y, Lehto T, Lächelt U. Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles. Adv Funct Mater. 2019;[Epub] doi:10.1002/adfm.201906432.

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