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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 10988 scientific papers returned from the database with the search filters currently being used below.

If you know of a publication that is not in this database and you feel it should be, please submit a new publication to the database and we'll get it in there.

Disc and Actin-Associated Protein 1 Influence Host Attachment in the Intestinal Parasite Giardia lamblia

Authors:
Steele-Ogus MC, Obenaus AM, Sniadecki NJ, Paredez AR
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.06.455446
Epub:
Not Epub
Abstract:
The deep-branching eukaryote Giardia lamblia is an extracellular parasite that attaches to the host intestine via a microtubule...
Delivery Method:
electroporation
Organism or Cell Type:
Giardia lamblia
Citation Extract:
Steele-Ogus MC, Obenaus AM, Sniadecki NJ, Paredez AR. Disc and Actin-Associated Protein 1 Influence Host Attachment in the Intestinal Parasite Giardia lamblia. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.06.455446.

Neuron Navigator 3 (NAV3) is Required for Heart Development

Authors:
Lv F, Yuan F, Lu X, Ge X, Shi L, Wang X, Liu D, Chen C
Citation:
Research Square. 2021;[preprint] doi:10.21203/rs.3.rs-734749/v1
Epub:
Not Epub
Abstract:
Background: As a tightly controlled biological process, cardiogenesis requires the specification and migration of a suite of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lv F, Yuan F, Lu X, Ge X, Shi L, Wang X, Liu D, Chen C. Neuron Navigator 3 (NAV3) is Required for Heart Development. Research Square. 2021;[preprint] doi:10.21203/rs.3.rs-734749/v1.

Adequate expression of neuropeptide Y is essential for the recovery of zebrafish motor function following spinal cord injury

Authors:
Cui C, Wang LF, Huang SB, Zhao P, Chen YQ, Wu YB, Qiao CM, Zhao WJ, Shen YQ
Citation:
Exp Neurol. 2021 Aug 4:113831. doi: 10.1016/j.expneurol.2021.113831. Online ahead of print
Epub:
Yes
Abstract:
In strong contrast to limited repair within the mammalian central nervous system, the spinal cord of adult zebrafish is capable...
Organism or Cell Type:
zebrafish
Citation Extract:
Cui C, Wang LF, Huang SB, Zhao P, Chen YQ, Wu YB, Qiao CM, Zhao WJ, Shen YQ. Adequate expression of neuropeptide Y is essential for the recovery of zebrafish motor function following spinal cord injury. Exp Neurol. 2021 Aug 4:113831. doi: 10.1016/j.expneurol.2021.113831. Online ahead of print.

Endothelial Semaphorin 3fb regulates Vegf pathway-mediated angiogenic sprouting

Authors:
Watterston C, Halabi R, McFarlane S, Childs SJ
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.03.454978
Epub:
Not Epub
Abstract:
Vessel growth integrates diverse extrinsic signals with intrinsic signaling cascades to coordinate cell migration and sprouting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Watterston C, Halabi R, McFarlane S, Childs SJ. Endothelial Semaphorin 3fb regulates Vegf pathway-mediated angiogenic sprouting. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.03.454978.

Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish

Authors:
Gao S, Wang Z, Wang L, Wang H, Yuan H, Liu X, Chen S, Chen Z, de Thé H, Zhang W, Zhang Y, Zhu J, Zhou J
Citation:
PLoS Genet. 2021;17(8):e1009693. doi:10.1371/journal.pgen.1009693
Epub:
Not Epub
Abstract:
The ubiquitin-proteasome system plays important roles in various biological processes as it degrades the majority of cellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao S, Wang Z, Wang L, Wang H, Yuan H, Liu X, Chen S, Chen Z, de Thé H, Zhang W, Zhang Y, Zhu J, Zhou J. Irf2bp2a regulates terminal granulopoiesis through proteasomal degradation of Gfi1aa in zebrafish. PLoS Genet. 2021;17(8):e1009693. doi:10.1371/journal.pgen.1009693.

Open-Label Evaluation of Eteplirsen in Patients with Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping: PROMOVI Trial

Authors:
McDonald CM, Shieh PB, Abdel-Hamid HZ, Connolly AM, Ciafaloni E, Wagner KR, Goemans N, Mercuri E, Khan N, Koenig E, Malhotra J, Zhang W, Han B, Mendell JR, the Italian DMD Telethon Registry Study Group, Leuven NMRC Registry Investigators, CINRG Duchenne Natural History Investigators, and PROMOVI Trial Clinical Investigators
Citation:
J Neuromuscul Dis. 2021 Jun 8;[Epub ahead of print]. doi:10.3233/JND-210643
Epub:
Yes
Abstract:
Background: Eteplirsen received accelerated FDA approval for treatment of Duchenne muscular dystrophy (DMD) with mutations...
Delivery Method:
i.v. infusion
Organism or Cell Type:
human
Citation Extract:
McDonald CM, Shieh PB, Abdel-Hamid HZ, Connolly AM, Ciafaloni E, Wagner KR, Goemans N, Mercuri E, Khan N, Koenig E, Malhotra J, Zhang W, Han B, Mendell JR, the Italian DMD Telethon Registry Study Group, Leuven NMRC Registry Investigators, CINRG Duchenne Natural History Investigators, and PROMOVI Trial Clinical Investigators. Open-Label Evaluation of Eteplirsen in Patients with Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping: PROMOVI Trial. J Neuromuscul Dis. 2021 Jun 8;[Epub ahead of print]. doi:10.3233/JND-210643.

The role of Musashi-1 in CEP290 c.2991+1655A>G cryptic exon splicing in Leber Congenital Amaurosis

Authors:
Ottaviani D, Lane A, Jovanovic K, Gardner JC, Sladen PE, Hau KL, Panes AB, Guarascio R, Hardcastle AJ, Cheetham ME
Citation:
bioRXiv. 2021;[preprint] doi:10.1101/2021.08.04.454918
Epub:
Not Epub
Abstract:
Human photoreceptors maximise alternative exon splicing to generate a unique set of gene isoforms. Conversely, the inclusion of...
Organism or Cell Type:
cell culture: human retinal organoids
Citation Extract:
Ottaviani D, Lane A, Jovanovic K, Gardner JC, Sladen PE, Hau KL, Panes AB, Guarascio R, Hardcastle AJ, Cheetham ME. The role of Musashi-1 in CEP290 c.2991+1655A>G cryptic exon splicing in Leber Congenital Amaurosis. bioRXiv. 2021;[preprint] doi:10.1101/2021.08.04.454918.

An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus

Authors:
Godden AM, Ward NJ, van der Lee M, Abu-Daya A, Guille M, Wheeler GN
Citation:
bioRxiv. 2021;[preprint] doi:10.1101/2021.08.05.454468
Epub:
Not Epub
Abstract:
In recent years CRISPR-Cas9 knockouts (KO) have become increasingly ultilised to study gene function. MicroRNAs (miRNAs) are...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Godden AM, Ward NJ, van der Lee M, Abu-Daya A, Guille M, Wheeler GN. An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus. bioRxiv. 2021;[preprint] doi:10.1101/2021.08.05.454468 .

Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis

Authors:
García-Castillo J, Alcaraz-Pérez F, Martínez-Balsalobre E, García-Moreno D, Rossmann MP, Fernández-Lajarín M, Bernabé-García M, Pérez-Oliva AB, Rodríguez-Cortez VC, Clara Bueno C, Adatto I, Agarwal S, Menéndez P, Zon LI, Mulero V, Cayuela ML
Citation:
Proc Nat Acad Sci. 2021;118(32):e2015528118. doi:10.1073/pnas.2015528118
Epub:
Not Epub
Abstract:
Dyskeratosis congenita (DC) is a rare inherited bone marrow failure and cancer predisposition syndrome caused by mutations in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
García-Castillo J, Alcaraz-Pérez F, Martínez-Balsalobre E, García-Moreno D, Rossmann MP, Fernández-Lajarín M, Bernabé-García M, Pérez-Oliva AB, Rodríguez-Cortez VC, Clara Bueno C, Adatto I, Agarwal S, Menéndez P, Zon LI, Mulero V, Cayuela ML. Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis. Proc Nat Acad Sci. 2021;118(32):e2015528118. doi:10.1073/pnas.2015528118.

Identification of de novo EP300 and PLAU variants in a patient with Rubinstein-Taybi syndrome-related arterial vasculopathy and skeletal anomaly

Authors:
Park JE, Kim E, Lee D-W, Park TK, Kim MS, Jang SY, Ahn J, Park KB, Kim K-H, Park H-C, Ki C-S, Kim D-K
Citation:
Sci Rep. 2021;11(1):15931. doi:0.1038/s41598-021-95133-0
Epub:
Not Epub
Abstract:
Rubinstein-Taybi syndrome (RSTS) is a human genetic disorder characterized by distinctive craniofacial features, broad thumbs...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Park JE, Kim E, Lee D-W, Park TK, Kim MS, Jang SY, Ahn J, Park KB, Kim K-H, Park H-C, Ki C-S, Kim D-K. Identification of de novo EP300 and PLAU variants in a patient with Rubinstein-Taybi syndrome-related arterial vasculopathy and skeletal anomaly. Sci Rep. 2021;11(1):15931. doi:0.1038/s41598-021-95133-0.

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